Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Kanalli, Prakruthi; Kundapur, Rohan R.; Joseph, Manu M. Title A name given to the resource Betel leaf-mediated zinc oxide nanoparticle-coated silk fibres: a sustainable approach for biomedical applications Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2025 Source A related resource from which the described resource is derived RSC Advances;Volume;15;Issue;38;pp.31162-31175 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1039/d5ra03600c" target="_blank" rel="noreferrer noopener">https://doi.org/10.1039/d5ra03600c</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105014610505?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105014610505?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Kanalli P., Department of Life Sciences, CHRIST University, Karnataka, Bengaluru, 560029, India; Kundapur R.R., Department of Life Sciences, CHRIST University, Karnataka, Bengaluru, 560029, India; Joseph M.M., Department of Life Sciences, CHRIST University, Karnataka, Bengaluru, 560029, India Description An account of the resource Clinical management of surgical site infections remains a challenge in biomedicine, where novel wound dressing materials are tested with a plethora of features. Here we describe a green and sustainable route to prepare biogenic zinc oxide nanoparticles (BZnONPs) using Piper betle leaf extract, which acts as a green reducing and stabilising agent. These biosynthesised nanoparticles were then used for the functional coating of degummed Bombyx mori silk fibers. Physico-chemical characterisation supports the efficient synthesis of crystalline, nanosized, and colloidal stable BZnONPs. The functionalization of silk fibers with BZnONPs resulted in the enhancement of the mechanical properties, tensile strength, and elasticity. Antibacterial testing proved the capability of the functional fibers against the strain Staphylococcus aureus. The as-synthesised fibers were biocompatible towards normal blood components, normal cells and exhibited slight toxicity toward cancer cells. Enhanced mechanical properties, antimicrobial action, and biocompatibility make BZnONP-coated silk fibers a leading player in various advanced biomedical devices, including sutures, wound dressings, tissue engineering scaffolds, and localised therapeutic platforms. Hence, this green nanotechnology approach opens up an alternative pathway toward the fabrication of multifunctional biomaterials with high translational value. 2025 The Royal Society of Chemistry. Publisher An entity responsible for making the resource available Royal Society of Chemistry Relation A related resource ISSN: 20462069; CODEN: RSCAC Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource All Open Access; Gold Open Access; Green Open Access Format The file format, physical medium, or dimensions of the resource online