ItemArticle

A highly effective curcumin analogue as naked eye colorimetric and fluorescent sensor for sensitive and selective detection of Hg2+ ions and its application on test strips and real sample analysis

Title
A highly effective curcumin analogue as naked eye colorimetric and fluorescent sensor for sensitive and selective detection of Hg2+ ions and its application on test strips and real sample analysis
Creator
Ramesh, D.K.; Pujar, Prasad Pralhad
Description
A thiophene appended curcumin-based colorimetric and fluorescent receptor (TAA) for selective recognition of Hg2+ ions was synthesized and characterized using 1H NMR, 13C NMR and LC-MS spectroscopic techniques. TAA facilitates detection of Hg2+ by a naked-eye color change from yellow to colorless in visible light, and fluorescence turn-off in UV light (365 nm). The observed fluorescence quenching is due to the chelation-enhanced fluorescence quenching (CHEQ). TAA exhibited excellent selectivity and sensitivity toward Hg2+ ions, even in the presence of competing cations. The binding constant (Ka) for Hg2+ ions was found to be 3.4 105 M?1, indicating a strong binding affinity. The binding mechanism was elucidated using DFT calculations and supported by LC-MS and FT-IR studies. TAA forms a 1 : 1 complex with Hg2+ ions, as confirmed by Job's plot analysis. Additionally, the colorimetric limit of detection was found to be 0.67 ?M, while the fluorometric limit of detection was found to be 0.24 ?M, which demonstrates the high sensitivity of TAA towards Hg2+. Furthermore, TAA probe exhibited successful detection of Hg2+ ions in real water samples. Also, it can serve as an effective on-site detection tool for mercury ions by a simple test strip method that requires no additional instrumentation. 2025 The Royal Society of Chemistry.
Source
RSC Advances;Volume;15;Issue;32;pp.25811-25822
Date
01-01-2025
Publisher
Royal Society of Chemistry
Coverage
Ramesh D.K., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bangalore, 560029, India, Centre for Renewable Energy and Environmental Sustainability, Christ University, Bangalore, 560029, India; Pujar P.P., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bangalore, 560029, India, Centre for Renewable Energy and Environmental Sustainability, Christ University, Bangalore, 560029, India
Rights
All Open Access; Gold Open Access; Green Open Access
Relation
ISSN: 20462069; CODEN: RSCAC
Format
online
Language
English
Type
Article

Citation

Ramesh, D.K.; Pujar, Prasad Pralhad, “A highly effective curcumin analogue as naked eye colorimetric and fluorescent sensor for sensitive and selective detection of Hg2+ ions and its application on test strips and real sample analysis,” CHRIST (Deemed To Be University) Institutional Repository, accessed June 18, 2026, https://archives.christuniversity.in/items/show/22578.

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