ItemArticle

Boron-/nitrogen-doped Ti3C2Tx MXene quantum dot-based sensor for determining an acute kidney injury biomarker

Title
Boron-/nitrogen-doped Ti3C2Tx MXene quantum dot-based sensor for determining an acute kidney injury biomarker
Creator
Rajeev, Rijo; Mariella Babu, Ann; Varghese, Anitha
Description
In this study, boron/nitrogen-doped Ti3C2Tx MXene quantum dots (BNMQDs) were synthesized via a hydrothermal technique and successfully brush-coated on a carbon fiber paper (CFP)-based electrode to detect creatinine (crt). The prepared MQDs were characterized by employing transmission electron microscopy (TEM), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), infrared spectroscopy (IR), and X-ray diffraction (XRD) analysis to study their physicochemical properties. The electrochemical performance of the modified CFP-based sensors toward crt detection was analyzed by employing cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Ti3C2Tx MQDs were prepared using the hydrothermal method and further doped with B and N using boric acid and p-phenylene diamine, respectively. The morphology of the obtained BNMQDs was quasi-spherical and exhibited uniform size with scattered particle sizes ranging from 5 to 9.5 nanometers. Owing to several surface-active sites, edge effects, and quantum confinement, the synthesized MQDs demonstrated enhanced electrooxidation of crt. Compared to BMQDs and NMQDs, BNMQDs showed superior sensing performance, with a wide linear range of 0.104-135 ?M and an LOD of 34.53 nM. The fabricated electrode also demonstrated high stability, reproducibility, and selectivity for the electrocatalytic oxidation of crt in real samples. 2025 The Royal Society of Chemistry.
Source
RSC Advances;Volume;15;Issue;39;pp.32929-32941
Date
01-01-2025
Publisher
Royal Society of Chemistry
Coverage
Rajeev R., Department of Chemistry, Christ University, Karnataka, Bangalore, 560029, India, Centre for Renewable Energy and Environmental Sustainability, Christ University, Karnataka, 560 029, India; Mariella Babu A., Department of Chemistry, Christ University, Karnataka, Bangalore, 560029, India, Centre for Renewable Energy and Environmental Sustainability, Christ University, Karnataka, 560 029, India; Varghese A., Department of Chemistry, Christ University, Karnataka, Bangalore, 560029, India, Centre for Renewable Energy and Environmental Sustainability, Christ University, Karnataka, 560 029, India
Rights
All Open Access; Gold Open Access; Green Open Access
Relation
ISSN: 20462069; CODEN: RSCAC
Format
online
Language
English
Type
Article

Citation

Rajeev, Rijo; Mariella Babu, Ann; Varghese, Anitha, “Boron-/nitrogen-doped Ti3C2Tx MXene quantum dot-based sensor for determining an acute kidney injury biomarker,” CHRIST (Deemed To Be University) Institutional Repository, accessed June 18, 2026, https://archives.christuniversity.in/items/show/22580.

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