Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Adhikari, Suman; Nath, Sourav; Saha, Koushik; Baildya, Nabajyoti; Kaminsky, Werner; Kumar, Malavika S; Roy, Subhadip; Das, Avijit Kumar Title A name given to the resource A turn-on bis-hydrazone fluorescent chemosensor for selective Cd2+ detection: synthesis, structural insights, and theoretical validation Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2026 Source A related resource from which the described resource is derived New Journal of Chemistry; Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1039/d6nj00362a" target="_blank" rel="noreferrer noopener">https://doi.org/10.1039/d6nj00362a</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105037888529?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105037888529?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Adhikari S., Department of Chemistry, Govt. Degree College, Tripura, Dharmanagar, (N)-799253, India; Nath S., Department of Chemistry, Govt. Degree College, Tripura, Dharmanagar, (N)-799253, India, Department of Chemistry and Vivekananda Centre for Research, Ramakrishna Mission Residential College, Narendrapur, Kolkata, 700103, India; Saha K., Department of Chemistry, Jadavpur University, West Bengal, Kolkata, 700032, India; Baildya N., Department of Chemistry, Milki High School, Milki, Malda, 732209, India; Kaminsky W., Department of Chemistry, University of Washington, Seattle, 98195, Washington, United States; Kumar M.S., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bangalore, 560029, India; Roy S., Department of Chemistry, The ICFAI University Tripura, Kamalghat, Mohanpur, Tripura, Agartala, 799210, India; Das A.K., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bangalore, 560029, India Description An account of the resource Heavy metal pollution, particularly from cadmium(ii) ions (Cd2+), causes severe environmental and health risks due to its acute toxicity, carcinogenicity, and bioaccumulation, leading to kidney damage, neurological disorders, and other physiological issues. Herein, we report the one-pot synthesis of a bis-hydrazone-based fluorescent probe L2H2O (1) for selective detection of Cd2+. Probe 1 was derived from isophthalaldehyde and 3-pyridylcarbonyl hydrazine and single-crystal X-ray diffraction discloses a well-defined binding pocket with pyridyl, imine, and carbonyl donor sites suitable for Cd2+ coordination. Probe 1 exhibits weak emission in CH3CN/HEPES buffer (9?:?1, v/v, pH 7.4) due to photoinduced electron transfer (PET) and unrestricted intramolecular rotations. Upon selective binding to Cd2+, 1 displays a pronounced turn-on fluorescence response with intensity enhancements of at ?324 nm and at 420 nm, accompanied by bathochromic shifts to 327 nm (?? = 3 nm) and 445 nm (?? = 25 nm) (?ex = 295 nm). The limit of detection (LOD) for probe 1 with metal Cd2+ is 3.39 M, with a binding constant of 5 103 M?1. 1H NMR titration, DFT-optimized geometries (B3LYP/6-31+G(d)/LANL2DZ), and simulated UV-Vis spectra further confirm binding of Cd2+, blocking PET and rigidifying the structure via chelation-enhanced fluorescence (CHEF). This work presents a modular hydrazone scaffold for developing selective Cd2+ sensors with potential application in environmental and biological monitoring. The Royal Society of Chemistry and the Centre National de la Recherche Scientifique, 2026. Publisher An entity responsible for making the resource available Royal Society of Chemistry Relation A related resource ISSN: 11440546; CODEN: NJCHE Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource Restricted Access; Hardcopy may be available in the library Format The file format, physical medium, or dimensions of the resource online