Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Thippesh, Deepak; Velayudhannair, Krishnakumar Title A name given to the resource Exploring the Pharmaceutical Potential of Meretrix casta (Gmelin, 1791) (Mollusca: Bivalvia) Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2025 Source A related resource from which the described resource is derived Asian Journal of Chemistry;Volume;37;Issue;6;pp.1469-1476 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.14233/ajchem.2025.33827" target="_blank" rel="noreferrer noopener">https://doi.org/10.14233/ajchem.2025.33827</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105012758639?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105012758639?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Thippesh D., Department of Life Sciences, Christ University, Dharmaram College Post, Hosur Road,, Bengaluru, 560029, India; Velayudhannair K., Department of Life Sciences, Christ University, Dharmaram College Post, Hosur Road,, Bengaluru, 560029, India Description An account of the resource Meretrix casta, a marine mollusk, has been recognized traditionally for its nutritional and medicinal properties. This study aims to investigate the pharmacological potential of M. casta extracts, specifically focusing on the antioxidant, hemolytic, anti-inflammatory and antimicrobial activities. The antioxidant activity, assessed via hydrogen peroxide scavenging and phosphomolybdate assays, revealed concentration-dependent inhibition, with the methanol extract showing 61.04% inhibition at 100 g/mL compared to 61.19% for ethyl acetate, while the standard ascorbic acid exhibited 87.80%. Anti-inflammatory activity was evaluated using heat-induced hemolysis, hypotonicity-induced hemolysis and protein denaturation assays. Both extracts demonstrated significant anti-inflammatory effects, with the ethyl acetate extract achieving 85.40% inhibition of hemolysis, closely matching acetylsalicylic acids 90.50% and methanol extract showing 87.60% at 100 g/mL. Antibacterial and antifungal assays demonstrated significant inhibitory effects against pathogenic bacteria and fungi, with the methanolic extract frequently exhibiting higher efficacy. These findings highlight the therapeutic potential of M. casta extracts as natural bioactive agents. Future investigations should aim to isolate and characterize the specific bioactive compounds underlying these pharmacological effects and to explore their mechanisms of action in detail. Such studies could pave the way for new therapies derived from marine biodiversity, addressing various health challenges. 2025 Asian Publication Corporation. All rights reserved. Subject The topic of the resource Medicinal marine mollusks; Meretrix casta; Natural antioxidants; Therapeutic marine resources Publisher An entity responsible for making the resource available Asian Publication Corporation Relation A related resource ISSN: 9707077; CODEN: AJCHE Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource All Open Access; Gold Open Access Format The file format, physical medium, or dimensions of the resource online