Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Ahmed, Nihal; Nagella, Praveen Title A name given to the resource Effect of heavy metal elicitation on antioxidants and andrographolide content in cell suspension cultures of Andrographis paniculata Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2025 Source A related resource from which the described resource is derived Plant Science Today;Volume;12;Issue;2; Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.14719/pst.3473" target="_blank" rel="noreferrer noopener">https://doi.org/10.14719/pst.3473</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105007621743?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105007621743?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Ahmed N., Department of Life Science, CHRIST (Deemed to be University), Bengaluru, 560 029, India; Nagella P., Department of Life Science, CHRIST (Deemed to be University), Bengaluru, 560 029, India Description An account of the resource Andrographolide, a bicyclic diterpene from Andrographis paniculata is of immense pharmaceutical importance. A. paniculata, an annual herb from Acanthaceae is widespread in the Indian subcontinent. Heavy metals act as abiotic elicitors. The study deals with the effect of mercury (Hg), cadmium (Cd) and arsenic (As) on andrographolide content, phenols and flavonoids and each of their correlation with the metal chelating and radical scavenging activity, in cell suspension cultures of A. paniculata. Andrographolide was estimated using HPLC, while other estimation methods were used for other metabolites. Four different concentrations of each of the heavy metal salts CdCl2, As2O3and HgCl2, were administered in liquid MS media containing 1 g of cells. Media without any metal served as control. Higher concentrations of Cd and As imparted a positive effect on andrographolide content, Hg imparted a negative effect. The cells were most sensitive to Hg and most tolerant to Cd. Cd could be the best choice as an elicitor for increased production of andrographolide. While phenols show a positive correlation with antioxidants, flavonoids and andrographolides do not show a positive correlation with antioxidants. The Author(s). Subject The topic of the resource Andrographis paniculata; andrographolide; arsenic; cadmium; flavonoids; mercury; phenols Publisher An entity responsible for making the resource available Horizon e-Publishing Group Relation A related resource ISSN: 23481900; Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource All Open Access; Gold Open Access; Green Open Access Format The file format, physical medium, or dimensions of the resource online