Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Priyadarshini, Pragyan; Sarojini, Suma Title A name given to the resource Metabolite profiling and bioactivity assessment of diverse endophytic fungi from the endangered plant, Nilgirianthus ciliatus Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2025 Source A related resource from which the described resource is derived Plant Science Today;Volume;12;Issue;2; Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.14719/pst.5333" target="_blank" rel="noreferrer noopener">https://doi.org/10.14719/pst.5333</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105001959992?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105001959992?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Priyadarshini P., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560 029, India; Sarojini S., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560 029, India Description An account of the resource Endophytic fungi are potential sources of bioactive compounds with therapeutic properties. This study investigated the fungal endophytes associated with Nilgirianthus ciliatus, an endangered medicinal plant, to discover its secondary metabolites and bioactivities. Molecular analysis revealed the prominent species to be Aspergillus niger, Didymella sp., Trichoderma viride, Bipolaris zeicola and Nigrospora sphaerica. Alkaloids, flavonoids, phenolics, terpenes and saponins were detected in ethyl acetate extracts employing phytochemical screening. Didymella sp. has showed the highest level of antioxidant activity, demonstrating strong DPPH radical scavenging and reduction capability. T. viride had strong antibacterial action against Klebsiella pneumoniae and Escherichia coli, meanwhile Didymella sp. and N. sphaerica were most effective against E. coli. GC-MS analysis uncovered many bioactive chemicals, including trans-farnesol and pentadecanoic acid, which are renowned for their antibacterial and antioxidant properties. These findings highlight the presence of the rich variety of diverse endophytic fungi harboring such medicinal plants, which offer promising applications in medicine, biotechnology and agriculture as sources of novel bioactive compounds. Further exploration and characterization of these strains could unlock valuable sustainable resources for various industries. The Author(s). Subject The topic of the resource antibacterial; antioxidant; didymellanosine; endophytic fungi; Nilgirianthus ciliatus Publisher An entity responsible for making the resource available Horizon e-Publishing Group Relation A related resource ISSN: 23481900; Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource All Open Access; Gold Open Access; Green Open Access Format The file format, physical medium, or dimensions of the resource online