Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Santhosh, Sandhya Kalathilparambil; Sarojini, Suma Title A name given to the resource Antibiofilm and anti-quorum properties of ethanolic leaf extracts of Syzygium jambos and Psidium guajava and their gel formulation for wound healing applications Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2025 Source A related resource from which the described resource is derived Plant Science Today;Volume;12;Issue;2; Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.14719/pst.6365" target="_blank" rel="noreferrer noopener">https://doi.org/10.14719/pst.6365</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105001875275?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105001875275?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Santhosh S.K., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560 029, India; Sarojini S., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560 029, India Description An account of the resource Most bacterial species today have evolved with time and gained resistance to a wide range of antibiotics, primarily due to formation of biofilms and ?-lactamases. Many phytochemicals have been explored for their ability to inhibit bacterial biofilms. The present study sheds light on antibiofilm properties of two such plants viz. Psidium guajava and Syzygium jambos, of the Myrtaceae family. They were found to be effective against four different biofilm forming pathogens - Chromobacterium violaceum, Klebsiella pneumoniae, Pseudomonas aeruginosa and Staphylococcus aureus. Synergistic use of the plant extracts showed slightly better antibacterial activity than a single extract. Quorum sensing being one of the key factors required for biofilm formation, the isolate Chromobacterium violaceum was used as the indicator organism to study the anti-quorum properties of the plant extracts. At 10 mg/mL, ethanolic extract of S. jambos inhibited violacein pigment the most (78.84%) and therefore can be considered as a quorum sensing inhibitor (QSI). Since silver nanoparticles (AgNPs) have become increasingly significant in the field of drug delivery, they may be utilized to coat implants to avoid subsequent infections in patients who have had implant surgery and to reduce biofilm development in pathogens. In the present study, five gels were formulated using plant extracts and AgNPs, of which two showed promising results in wound healing assay. The non-toxic nature of the synthesized gels has been verified by studies on L-929 mouse fibroblast cell lines, which opens the door for their prospective application as topical treatments to accelerate the healing process in both acute and chronic wounds. Given that S. aureus and P. aeruginosa are the most commonly isolated bacteria from diabetic foot ulcers, the resulting gels can considerably curb the spread of infection and gangrene and thus prevent amputation. Copyright: The Author(s) Subject The topic of the resource AgNPs; anti-quorum; antibiofilm; Psidium guajava; Syzygium jambos; wound healing Publisher An entity responsible for making the resource available Horizon e-Publishing Group Relation A related resource ISSN: 23481900; Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource All Open Access; Gold Open Access; Green Open Access Format The file format, physical medium, or dimensions of the resource online