Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource George, Arvind; Paari, Kuppusamy Alagesan Title A name given to the resource Sustainable mosquito control: A tool in the fight against Aedes aegypti using Flemingia wightiana Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2025 Source A related resource from which the described resource is derived Plant Science Today;Volume;12;Issue;3; Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.14719/pst.7292" target="_blank" rel="noreferrer noopener">https://doi.org/10.14719/pst.7292</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105009516456?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105009516456?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant George A., Department of Life Sciences, CHRIST University, Karnataka, Bengaluru, 560 029, India; Paari K.A. Description An account of the resource Mosquito-borne diseases, particularly those transmitted by Aedes aegypti, have been proven to be a global health challenge. A. aegypti, a major vector of Zika virus, Dengue virus, Chikungunya, is traditionally controlled through synthetic insecticides. However, the factor of environmental issues and rising insecticide resistant breeds have prompted the exploration of eco-friendly and sustainable alternatives. Here, we attempt to use the leaf extract of Flemingia wightiana to produce silver nanoparticles (FWAgNP). The construct of AgNPs was first indicated by UV-Vis spectroscopy, with a peak at 461 nm. NP was then characterized by SEM, EDX and functional groups were analyzed using FTIR spectroscopy. Safety assessments of synthesized NP were carried out on Oreochromis niloticus. Percentage mortality was studied on A. Aegypti with both test samples, FWAgNP and FWME. FWAgNP were found to be effective; the lowest percentage mortality of 70 % was recorded for forth instar larvae and 100 % mortality was observed in the first and second instar larvae. Oxidative stress assays such as AChe, SOD, CAT, GSH and GST were carried out. SOD, CAT and GSH showed significant elevated levels. GST and AChe levels reduced as the concentration increased, indicating the role of test samples in oxidative stress. Antiviral assay was conducted to check the effect of AgNPs in inhibiting the growth and infection of Zika virus (ZIKV) on Vero cells. The percentage inhibition property of AgNP was found to be 25 %. In conclusion, the developed FWAgNPs have significant potential in the control of vectors and a limited inhibitory activity on Zika virus. The Author(s). Subject The topic of the resource larvicide; nanoparticles; oxidative stress; Zika virus Publisher An entity responsible for making the resource available Horizon e-Publishing Group Relation A related resource ISSN: 23481900; Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource All Open Access; Gold Open Access; Green Open Access Format The file format, physical medium, or dimensions of the resource online