ItemArticle

Phytochemical screening, GC-MS profiling and in vitro antioxidant activity of leaves of Dysoxylum malabaricum Bedd. ex C. DC.

Title
Phytochemical screening, GC-MS profiling and in vitro antioxidant activity of leaves of Dysoxylum malabaricum Bedd. ex C. DC.
Creator
Mathew, Ann Susan; Xavier, Jobi
Description
Plants are a rich source of phytocompounds, have remained an integral part of traditional medicine and serve as alternativesto modern medical treatments. They are powerful sources of antioxidants and the bioactive compounds in plants are associated with a wide range of pharmacological activities. Dysoxylum malabaricum is a species of medium to large-sized trees from the Meliaceae family that is widely found in the Southern Western Ghats and its bark and fruits are used in traditional medicine. Even though it is widely used as ethnomedicinal plant, limited research has been done on its phytochemical constituents, especially the phytocompounds presentin the leaves. Therefore, this study aims to extensively explore and identify the phytocompounds and bioactive elements found in the leaf extracts of D. malabaricum. Extract was prepared from leaves of D. malabaricum using soxhlet extraction method in different solvents (methanol, water and chloroform). Quantitative estimation of phytochemicals and in vitro antioxidant assays were carried out, followed by chemical profiling of the extracts using GC-MS, which revealed the presence of many important secondary bioactive compounds. The methanolic extract showed a higher concentration of phenolics (67.88 0.26 mg GAE/g) and flavonoids (57.55 0.23 mg QE/g) when compared to aqueous and chloroform extracts. The methanolic extract also demonstrated remarkable DPPH scavenging (with IC50value 32.45 0.22 g/mL) and ferric reduction activities. The results demonstrate that D. malabaricum is an effective source of bioactive and antioxidant compounds. 2025 Horizon e-Publishing Group. All rights reserved.
Source
Plant Science Today;Volume;12;Issue;3;
Date
01-01-2025
Publisher
Horizon e-Publishing Group
Subject
antioxidants; bioactive compounds; dysoxylum; GC-MS analysis
Coverage
Mathew A.S., Department of Life Sciences, Christ University, Karnataka, Bangalore, 560 029, India; Xavier J., Department of Life Sciences, Christ University, Karnataka, Bangalore, 560 029, India
Rights
All Open Access; Gold Open Access; Green Open Access
Relation
ISSN: 23481900;
Format
online
Language
English
Type
Article

Citation

Mathew, Ann Susan; Xavier, Jobi, “Phytochemical screening, GC-MS profiling and in vitro antioxidant activity of leaves of Dysoxylum malabaricum Bedd. ex C. DC.,” CHRIST (Deemed To Be University) Institutional Repository, accessed June 18, 2026, https://archives.christuniversity.in/items/show/23279.

Output Formats