Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Lakshman, Priyanka; Mayegowda, Shilpa Borehalli.; Murthy, Sushma S.; Gadilingappa, Manjula Nagalapur Title A name given to the resource Phenotypic detection of ?-lactamases producing Klebsiella pneumoniae and Acinetobacter baumannii isolated from the respiratory tract infections Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2025 Source A related resource from which the described resource is derived IP International Journal of Medical Microbiology and Tropical Diseases;Volume;11;Issue;4;pp.483-492 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.18231/j.ijmmtd.11625.1758782202" target="_blank" rel="noreferrer noopener">https://doi.org/10.18231/j.ijmmtd.11625.1758782202</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105035090671?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105035090671?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Lakshman P., Dept. of Microbiology, School of Basic and Applied Sciences, Dayananda Sagar University, Karnataka, Bengaluru, India; Mayegowda S.B., Dept. of Psychology, CHRIST University, Kengeri Campus, Karnataka, Bengaluru, India; Murthy S.S., Dept. of Microbiology and Botany, School of Sciences Jain (Deemed to be university), Karnataka, Bengaluru, India; Gadilingappa M.N., Dept. of Microbiology, School of Basic and Applied Sciences, Dayananda Sagar University, Karnataka, Bengaluru, India Description An account of the resource Introduction: With limited treatment options and emerging antimicrobial resistance amongst bacterial pathogens in hospital settings, the alarming condition needs to be addressed. Aim and Objective: The study aimed to determine the antibiotic susceptibility (AST) patterns, and extended spectrum ?-lactamases (ESBL) and Metallo ?-lactamases (MBL) production in Klebsiella pneumoniae and Acinetobacter baumannii isolated from respiratory tract infections (RTI). Materials and Methods: Current study, 1624 samples (sputum, tracheal secretions, suction tip) were collected during June 2020 to September 2022, phenotypically characterized by antibiotic sensitivity test (AST), Extended Spectrum Beta lactamases and Metallo Beta lactamases detection. Results: Of 12.3% (200 isolates), recorded prevalence rate of K. pneumoniae was 10.3% while, A. baumannii showed 1.9%. Following AST, K. pneumoniae displayed highest resistance against Ampicillin (95%), followed by Amoxycillin/clavulanic acid (91%), lowest recorded susceptibility for Tigecycline (39.2%). While, A. baumannii expressed susceptibility to Carbapenem group and Ciprofloxacin (84.3%), lowest Tigecycline (50%). Overall study exhibited Colistin retaining its activity with 100% sensitivity. ESBL production in K. pneumoniae was 31% and 0% in A. baumannii. While, MBL producers was 11%, K. pneumoniae and A. baumannii recorded at 9.5% and 25% respectively. Conclusion: The increasing rates of ESBL producers is concerning, and the current study highlights use of Colistin as the best available antimicrobial for treating such RTI pathogens. Therefore, continuous monitoring of antibiotic-resistant profiles will help to guide effective antimicrobial therapy and management. 2025 The Author(s), Published by Innovative Publications. This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. https://creativecommons.org/licenses/by-nc-sa/4.0/ Subject The topic of the resource Antibiotic susceptibility test; Antimicrobials; Colistin; ESBL; MBL Publisher An entity responsible for making the resource available IP Innovative Publication Pvt. Ltd. Relation A related resource ISSN: 25814753; Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource All Open Access; Hybrid Gold Open Access Format The file format, physical medium, or dimensions of the resource online