Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource George, Merin; Krishnan, Sharath; Madan, Anshika; Ansar, Syed Sana; Merston, John; Meganathan, Gomathy; Pappuswamy, Manikantan Title A name given to the resource Antibacterial Efficacy of Oreochromis niloticus Mucus and its Characterization Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2025 Source A related resource from which the described resource is derived Journal of Pure and Applied Microbiology;Volume;19;Issue;2;pp.1448-1459 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.22207/JPAM.19.2.48" target="_blank" rel="noreferrer noopener">https://doi.org/10.22207/JPAM.19.2.48</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105007430754?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105007430754?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant George M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Krishnan S., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Madan A., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Ansar S.S., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Merston J., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Meganathan G., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Pappuswamy M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, India Description An account of the resource Investigating new antimicrobial agents from various biological sources is necessary due to the rise of bacteria that are resistant to drugs. A neglected source of bioactive substances with possible antibacterial qualities is fish, especially Oreochromis niloticus (Nile tilapia). This study identifies the bioactive components of extracts made from O. niloticus and examines their antibacterial activity. PBS and sterile water were used to remove fish mucus using a solvent. Using the agar well diffusion method, extracts were tested for antibacterial activity against a panel of Gram-positive bacteria (Staphylococcus aureus, B. cereus), Gram-negative bacteria (Klebsiella pneumoniae, P. aeruginosa), and fungus (Candida albicans). The presence of hydroxyl and amide functional groups, which are suggestive of proteins and polyphenolic substances, was further validated by Fourier-transform infrared spectroscopy (FTIR). The study demonstrates O. niloticuss antibacterial potential, with its mucus being an exceptionally abundant source of bioactive substances. These results highlight the potential of fish-derived antimicrobial compounds as substitutes for traditional antibiotics. The isolation, structural clarification, and possible therapeutic uses of these chemicals should be the main areas of future study. Furthermore, to guarantee the efficacy and safety of these natural compounds, knowledge of their toxicity profiles and mechanisms of action is crucial. In the fight against antibiotic resistance, this study helps to establish sustainable bioresources and expands our knowledge of O. niloticuss antibacterial potential. The Author(s) 2025. Subject The topic of the resource Aqueous Extract; Lyophilised Mucus; Nile Tilapia; Physical Barrier; Well Diffusion Assay Publisher An entity responsible for making the resource available Journal of Pure and Applied Microbiology Relation A related resource ISSN: 9737510; Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource All Open Access; Gold Open Access; Green Open Access Format The file format, physical medium, or dimensions of the resource online