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                <text>Faculty Publications</text>
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          <name>Creator</name>
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              <text>Meganathan, Gomathy; Pappuswamy, Manikantan</text>
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          <name>Title</name>
          <description>A name given to the resource</description>
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              <text>Characterization, molecular docking, and therapeutic properties of biomaterial obtained from Pangasianodon hypopthalmus</text>
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          <name>Date</name>
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              <text>01-01-2026</text>
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              <text>Natural Resources for Human Health;Volume;6;Issue;1;pp.40-56</text>
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              <text>&lt;a href="https://doi.org/10.53365/nrfhh/210624" target="_blank" rel="noreferrer noopener"&gt;https://doi.org/10.53365/nrfhh/210624&lt;/a&gt; &lt;br /&gt;&lt;br /&gt;&lt;a href="https://www.scopus.com/pages/publications/105028306910?origin=resultslist" target="_blank" rel="noreferrer noopener"&gt;https://www.scopus.com/pages/publications/105028306910?origin=resultslist&lt;/a&gt;</text>
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              <text>Meganathan G., Department of Life Sciences, Christ University (Deemed to be University), Bengaluru, India; Pappuswamy M., Department of Life Sciences, Christ University (Deemed to be University), Bengaluru, India</text>
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              <text>The therapeutic properties of fish have been recognized since ancient times because of the presence of various fatty acids. Oleic acid, which is a mono-unsaturated fatty acid, is known for curing heart-related diseases and promoting brain health. Our study is a first attempt to evaluate the Anti-inflammatory activity, Anti-oxidant activity and perform characterization studies on mucus obtained from Pangasianodon hypopthalmus and explore its therapeutic properties. Anti-inflammatory property evaluation was performed via, albumin denaturation assay showing an 81% inhibition rate and RBC hemolysis assay with a 76.79% inhibition rate, anti-oxidant activity evaluation performed using the DPPH assay showed an 80% radical scavenging activity at 150?g/mL concentration. Overall results showed that anti-inflammatory was highest at 100mg/mL concentration and anti-oxidant activity was highest at 150?g/mL concentration. Characterization studies involved FTIR, NMR and GCMS analysis. Simulation study was performed on selected compound (ligand) against selected targets. From GC-MS analysis, C18 H34 O2 (Oleic acid), was found to be present at higher concentration. Docking studies revealed good binding energy and strong hydrogen bonding between oleic acid and TNF-?, with a binding energy of ?5.3 kcal/mol, thereby demonstrating strong anti-inflammatory activity and wound-healing potency. Further in-vitro and in-vivo analysis has to be performed to develop potential drug for therapeutic purpose.  2026 Visagaa Publishing House.</text>
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              <text>Anti-inflammatory property; Biomaterial characterization; Molecular docking studies bioactive compounds; Pangasianodon hypopthalmus</text>
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              <text>Visagaa Publishing House</text>
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              <text>ISSN: 25831194;</text>
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              <text>English</text>
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              <text>All Open Access; Hybrid Gold Open Access</text>
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