Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Paladhi, Amogha G.; Manjunath, B.T. Title A name given to the resource An ethnopharmacological investigation of antidiabetic plants used in Gudibande Taluk, Chikkaballapur District, Karnataka, India Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2025 Source A related resource from which the described resource is derived Medicinal Plants;Volume;17;Issue;2;pp.272-279 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.5958/0975-6892.2025.00027.2" target="_blank" rel="noreferrer noopener">https://doi.org/10.5958/0975-6892.2025.00027.2</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105012557789?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105012557789?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Paladhi A.G., Department of Life Sciences, Christ (Deemed to be University), Hosur Main Road, Karnataka, Bengaluru, 560029, India; Manjunath B.T., Department of Life Sciences, Christ (Deemed to be University), Hosur Main Road, Karnataka, Bengaluru, 560029, India Description An account of the resource This research offers an ethnopharmacological investigation of the application of medicinal plants for treating diabetes. An ethnobotanical survey was conducted in Gudibande Taluk, Chikkaballapur District, Karnataka, India. Traditional healers were interviewed about 28 plant species belonging to 22 families being used in treating diabetes. Fabaceae was recorded as the most prevalent family with maximum number of plant species. Leaves of 41.9% plant species were noticed as the most frequently plant parts used followed by fruits (12.9%), seeds (12.9%), and root (6.5%) for the treatment of diabetes. The study also comprized molecular docking and molecular dynamics simulations to assess the pharmacological potential of bioactive compounds, focused on interactions with human pancreatic alpha-amylase. Two ligands, metformin and compound 197678, were examined with GROMACS for 200 ns. The findings showed that all protein-ligand complexes maintained structural stability, with RMSD, RMSF, Rg, SASA, and hydrogen bonding metrics indicating the stability and possible effectiveness of these compounds. Conservation issues were also recognized, such as habitat loss and ignorance of younger generations about exposure of traditional knowledge. The results of the study underscored the healing potential of neglected medicinal flora and promote community-driven conservation of plants important for diabetes treatment. 2025, Indian journals. All rights reserved. Subject The topic of the resource Conservation; diabetes; ethnobotany; ethnomedicine; simulation; traditional healer Publisher An entity responsible for making the resource available Indian journals Relation A related resource ISSN: 9754261; Language A language of the resource English Type The nature or genre of the resource Article Rights Information about rights held in and over the resource All Open Access; Hybrid Gold Open Access Format The file format, physical medium, or dimensions of the resource online