Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Book Chapter Faculty Publications- Book Chapter Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Manuel, Manju Title A name given to the resource Biocompatibility and toxicity of nanomaterials in the designing of tools for the diagnosis of infectious diseases Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2025 Source A related resource from which the described resource is derived Nano-Biosensor Technologies for Diagnosis of Infectious Diseases;pp.449-468 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1002/9781394287697.ch15" target="_blank" rel="noreferrer noopener">https://doi.org/10.1002/9781394287697.ch15</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105010120402?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105010120402?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Manuel M., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India Description An account of the resource Nanomaterials have revolutionized the landscape of infectious disease diagnostics by offering unparalleled advantages in terms of sensitivity, specificity, and rapidity. However, their integration into diagnostic tools necessitates a profound understanding of their biocompatibility and toxicity profiles to ensure both diagnostic accuracy and patient life. The successful translation of these nanomaterials into practical diagnostic tools hinges on a thorough understanding of their biocompatibility and toxicity. Biocompatibility, a fundamental characteristic of nanomaterials refers to their ability to coexist with biological systems without causing harm or triggering immune responses. This chapter unfolds the pivotal role of biocompatibility assessment, examining the compatibility of nanomaterials with biological systems. In vitro and in vivo evaluation methods, and adherence to regulatory standards, are emphasized as essential components of biocompatibility analysis. Simultaneously, the exploration of nanotoxicity and its hazardous effect highlights the significance of establishing safe exposure limits. Toxicity is a pressing concern when dealing with nanomaterials. The chapter explores the factors that contribute to nanomaterials toxicity, including size-dependent effects, surface modifications, and the route of exposure. It also delves into the mechanisms by which nanomaterials can exert toxicity, such as reactive oxygen species, reaction with surface expanded group, and penetration into the cell. To mitigate the potential risk associated with nanomaterials, the chapter discusses strategies for improving biocompatibility. Finally, it gives a glance into the various tools prepared highlighting the successful integration of biocompatible nanotoxicity of nanomaterials into infectious disease diagnostics. Ultimately, this chapter emphasizes the need for comprehensive biocompatibility and toxicity evaluation as integral components of designing effective and safe diagnostic tools thereby contributing to the advancement of healthcare through cutting-edge nanotechnology. 2025 Scrivener Publishing LLC. All rights reserved. Subject The topic of the resource Biocompatibility; Infectious diseases; Nanomaterials; Toxicity Publisher An entity responsible for making the resource available wiley Relation A related resource ISBN: 978-139428769-7; 978-139428766-6; Language A language of the resource English Type The nature or genre of the resource Book chapter Rights Information about rights held in and over the resource Restricted Access; Hardcopy may be available in the library Format The file format, physical medium, or dimensions of the resource online