Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Faculty Publications Book Chapter Faculty Publications- Book Chapter Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Jadhav, Vikram; Pardeshi, Shaktising; More, Bhagyashri; Merugu, Ramchander; Mayegowda, Shilpa Borehalli Title A name given to the resource Quorum quenching for biocontrol of plant diseases Date A point or period of time associated with an event in the lifecycle of the resource 01-01-2025 Source A related resource from which the described resource is derived Harnessing Quorum Quenching for Disease Management;pp.201-224 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/B978-0-443-34178-6.00007-5" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/B978-0-443-34178-6.00007-5</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105023921004?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105023921004?origin=resultslist</a> Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Jadhav V., Department of Chemistry, K. K. Wagh Arts. Science and Commerce College Pimpalgaon (B), Maharashtra, Nashik, India; Pardeshi S., Karmaveer Punjababa Goverdhane Arts, Commerce, and Science College Igatpuri, Maharashtra, Nashik, India; More B., Camp Education Society's, Dr. Arvind B. Telang Senior College Arts, Commerce and Science, Pradhikaran Nigdi, Maharashtra, Pune, India; Merugu R., Department of Biochemistry, Mahatma Gandhi University, Telengana, Nalgonda, India; Mayegowda S.B., Department of Psychology, CHRIST University, Kengeri Campus, Karnataka, Bengaluru, India Description An account of the resource Bacterial pathogens have become a significant threat to world agriculture, causing tremendous crop losses and economic instability. The traditional mode of disease control by chemical pesticides is quickly becoming obsolete with resistant strains and environmental issues. Quorum quenching (QQ) is thus a promising alternative that is sustainable enough to target the bacterial communication system known as quorum sensing (QS). QS enables bacteria to coordinate their virulence factors, biofilm formation, and host colonization according to population density. Attenuating bacterial virulence is achieved through QQ by enzymatic degradation, signal molecule mimicry, or inactivation of autoinducers but without directly killing the pathogens, thereby not allowing resistance. This chapter describes the mechanism of QQ and several applications of this principle in controlling plant diseases through biocontrol agents. Enzymatic hydrolysis catalyzed by lactonases, acylases, and oxidoreductases inactivate autoinducers that include acyl-homoserine lactones and autoinducer-2 (AI-2). Mimicry of QS signal molecules is through synthetic or natural analogs that competitively inhibit QS receptors; sequestration occurs when autoinducers are captured to avert their involvement in QS. QQ is quite efficient in the lab and the field, both as microbial biocontrol agents against the pathogens Pectobacterium carotovorum and Xanthomonas campestris, as well as in transgenic plants expressing QQ enzymes. QQ still faces challenges in developing resistance, delivering QQ enzymes, and integrating with integrated pest management strategies. Future research could be concentrated on optimizing QQ strategies, designing new enzymes with better stability and specificity, and assessing the environmental impact of QQ-based biocontrol. Breakthroughs in synthetic biology and protein engineering would give way to new opportunities in the form of more potent biocontrol agents. The method of disease control in an environment-friendly manner and ensuring food security across the globe will be targeted by overcoming the challenges and through novel research with QQ-based biocontrol. 2026 Elsevier Inc. All rights reserved. Subject The topic of the resource bacterial pathogens; biocontrol; plant diseases; Quorum quenching; quorum sensing Publisher An entity responsible for making the resource available Elsevier Relation A related resource ISBN: 978-044334178-6; 978-044334179-3; Language A language of the resource English Type The nature or genre of the resource Book chapter Rights Information about rights held in and over the resource Restricted Access; Hardcopy may be available in the library Format The file format, physical medium, or dimensions of the resource online