A data-driven approach to predicting breast cancer recurrence with hybrid machine learning models
breast cancer; logistic regression; machine learning; random forest; recurrence
Breast cancer recurrence is one of the most significant medical concern, and accurate recurrence models can assist in early intervention and treatment planning. Breast cancer recurrent remains as one of the most critical concern for patients prognosis and treatment planning. Accuracy Predicting individual recurrence risk is crucial for the development of precise therapy, specialy for those patients with high-risk profiles. In the study proposes a hybrid machine learning approach that uses the computational modeling and the medical information to predict the recurrence of breast cancer in a patient. The dataset contains the medical and patient information like the age, tumor size, lymph node involvement, malignancy degree, location, irradiation status and recurrence class. This proposed approach begins with the process of data processing, handling the missing data values, features normalization and encoding of categorical variable into numerical format. The dataset is divided into two parts the training set and the testing set and the two selected models random forest and logistic regression models are trained independently. The predictions form both the model is stacked and a logistic regression meta-model is trained on these combined predictions. The evaluation of the model was conducted using the metrics such as accuracy, precision, recall, and F1 score. The designed hybrid model was able to achieve the accuracy of 97.66% with the precision, recall and F1 score all reaching around 98.15%. This study highlights the potential of hybrid machine learning techniques, improving the accuracy and reliability of machine learning models for breast cancer recurrence prediction. This development model can serve as a valuable tool for the medical industry to support decision making and assist in personalized treatment decisions, offering early detection of recurrence. This can enhance the treatment of a patient by supporting early detection and patients outcomes through targeted therapy. Copyright 2026 Techno-Press
Deepa, B.G.; Velmurugan, R.; Narender, M.; Suhaas, K.P.
Advances in Computational Design;Volume;11;Issue;1;pp.79-96
Restricted Access; Hardcopy may be available in the library
https://doi.org/10.12989/acd.2026.11.1.079 https://www.scopus.com/pages/publications/105031064136?origin=resultslist
Deepa B.G., Department of Computer Science, Christ University, Bangalore, India; Velmurugan R., Department of Computer Science, Kristu Jayanti (Deemed to be University), Bangalore, India; Narender M., Department of Computer Science and Engineering, The National Institute of Engineering, Mysore, India; Suhaas K.P., Department of Computer Science and Engineering, The National Institute of Engineering, Mysore, India
Balancing patient privacy and predictive accuracy through data anonymization in healthcare
AI analytics; data anonymization; GDPR; healthcare; HIPAA; k-anonymity; MIMIC-III; patient privacy; pseudonymization
Data anonymization in healthcare is essential for protecting sensitive patient information while enabling secure usage for research, analytics, and AI-driven clinical decision-making. In this study, the MIMIC-III - Deep Reinforcement Learning dataset was used, which contains comprehensive electronic health records (EHRs) of ICU patients. Data preprocessing was performed using Min-Max Normalization to scale numerical features and ensure consistency. Anonymization techniques such as pseudonymization, generalization, suppression, data masking, and statistical methods like k-anonymity, l-diversity, and t-closeness were applied to safeguard patient privacy. The anonymized dataset was then utilized for predictive modelling using AI techniques including Random Forest and LSTM. Results demonstrated that privacy was maintained with 0% PII leakage, while predictive accuracy remained high, achieving accuracy of 94.6%, precision of 93.8%, recall of 92.5%, and F1-score of 93.1%. This study highlights that effective data anonymization ensures compliance with HIPAA and GDPR while retaining the utility of healthcare data for advanced analytics and AI applications. 2026 Techno-Press
Kumar, Prem M.; Bhat, Archana; Bhagyalakshmi, Macherla; Nikila, G.S.
Advances in Computational Design;Volume;11;Issue;1;pp.47-62
https://doi.org/10.12989/acd.2026.11.1.047 https://www.scopus.com/pages/publications/105030972227?origin=resultslist
Kumar P.M., Willron Electronics, Bangalore, India; Bhat A., Department of Artificial Intelligence and Machine Learning, BMS Institute of Technology and Management, Bengaluru, India; Bhagyalakshmi M., School of Commerce, Finance and Accountancy, Christ University, Bangalore, India; Nikila G.S., OnGen, Bangalore, India
Stress-Driven Changes in Ascorbic Acid Levels in Raphanus Sativus: A Comparative Study
Abiotic Stress; Antioxidant Activity; Ascorbic Acid (AA); Reactive Oxygen Species (ROS); Red Radish (Raphanus Sativus)
Abiotic stresses such as extreme temperatures and salinity are known to significantly influence the nutritional quality of vegetables during cultivation and postharvest handling. However comparative study on how different abiotic stresses alter ascorbic acid stability in root vegetables like red radish is understudied. Thus, the present study was conducted to evaluate the effect of various abiotic stresses (heat, cold and salinity) on ascorbic acid (AA) levels and antioxidant activity in red radish (Raphanus sativus L.). DCPIP titration and DNPH UV-Vis spectrophotometric techniques were used to analyse the ascorbic acid content, and the DPPH radical scavenging assay was used to measure antioxidant capacity. The findings showed that as stress duration and intensity increased, the total AA content decreased significantly (p < 0.05). At high temperature (90 C), heat treatment resulted in a progressive decrease from 27.7 mg/100g to 20.8 mg/100g. Under cold stress, AA content increased slightly initially and then dropped by 22% on day 8. A two-phase response to salt stress was seen mild salt concentration leading to a moderately increased AA content, while severe salt concentration caused a 55% reduction after 72 hours. With an IC50 value of 8.27mg/mL, the antioxidant activity increased as extract concentration increased from 3.8% to 62.1% inhibition. According to these findings, red radish exhibits a short-term adaptive defence in mild stress situations but a significant decrease in AA in severe stress situations. These findings are consistent with previous reports in other related vegetables such as tomato, broccoli and spinach, where moderate abiotic stress increases antioxidant defences before degradation occurs. These results suggest the need for efficient postharvest management and stress-aware storage techniques to preserve the functional and health-promoting qualities of red radish. 2026 The Author(s).
Current Research in Nutrition and Food Science;Volume;14;Issue;1;pp.383-391
https://doi.org/10.12944/CRNFSJ.14.1.26 https://www.scopus.com/pages/publications/105037972599?origin=resultslist
Sridhar A., Department of Life Sciences, Christ University, Karnataka, Bangalore, India; Umesh M., Department of Life Sciences, Christ University, Karnataka, Bangalore, India
Feature Engineering for Epileptic Seizure Classification Using SeqBoostNet
AdaBoost; Deep Learning; Epileptic Seizure; FFT; LSTM; Machine Learning; UMAP
Epileptic seizure, a severe neurological condition, profoundly impacts patients social lives, necessitating precise diagnosis for classification and prediction. This study addresses the need for reliable automated seizure detection in epilepsy by employing Artificial Intelligence (AI) driven analysis of Electroencephalography (EEG) signals. Key innovations include combining spectral and temporal features using Uniform Manifold Approximation and Projection (UMAP) with Fast Fourier Transformation (FFT), and the introduction of the Sequential Boosting Network (SeqBoostNet), a robust stacking model integrating machine learning and deep learning for effective seizure classification. Validated on benchmark datasets such as the BONN dataset from the UCI repository and the BEED from the Bangalore EEG Epilepsy Dataset, this approach achieved high accuracy, distinguishing Focal and Generalized seizure onsets with 95.91% accuracy and overall average accuracies of 96.71% on BEED and 97.11% on BONN. Existing models frequently struggle with the variability of seizure events. However, these findings underscore the models strength in distinguishing between seizure onset types, even with the inherent fluctuations in seizure patterns. This research not only advances automated seizure detection but also underscores the value of integrating AI with EEG analysis to improve neurological diagnostics, offering the potential for significant enhancements in diagnostic accuracy and patient outcomes. 2025 University of Bahrain. All rights reserved.
International Journal of Computing and Digital Systems;Volume;17;Issue;1;
https://doi.org/10.12785/ijcds/1571020131 https://www.scopus.com/pages/publications/85217538815?origin=resultslist
Najmusseher, Department, of Computer Science, CHRIST (Deemed to be University), Central Campus, Bangalore, 560029, India; Banu N.P.K., Department, of Computer Science, CHRIST (Deemed to be University), Central Campus, Bangalore, 560029, India
ODD SUN-FREE TRIANGULATED GRAPHS ARE S-PERFECT
Extended sun graph; S-perfect graphs; Sun graph
For a graph G with the vertex set V (G) and the edge set E(G) and a star subgraph S of G, let ?S(G) be the maximum number of vertices in G such that no two of them are in the same star subgraph S and ?S(G) be the minimum number of star sub-graph S that cover the vertices of G. A graph G is called S-perfect if for every induced subgraph H of G, ?S(H) = ?S(H). Motivated by perfect graphs discovered by Berge, Ravindra in-troduced S-perfect graphs. In this paper we prove that a trian-gulated graph is S-perfect if and only if G is odd sun-free. This result leads to a conjecture which if proved is a structural char-acterization of S-perfect graphs in terms of forbidden subgraphs. 2025, Diogenes Co. Ltd.. All rights reserved.
Ravindra, G.; Ghosh, Sanghita; Abraham, V.M.
International Journal of Applied Mathematics;Volume;38;Issue;2S;pp.423-432
https://doi.org/10.12732/ijam.v38i2s.92 https://www.scopus.com/pages/publications/105017183803?origin=resultslist
Ravindra G., Department of Mathematics, CHRIST (Deemed to be University), Bengaluru, India; Ghosh S., Department of Mathematics, CHRIST (Deemed to be University), Bengaluru, India; Abraham V.M., Department of Mathematics, CHRIST (Deemed to be University), Bengaluru, India
VERTEX COLOURING OF FINITE NETWORKS WITH RESPECT TO AVERAGE DISTANCE
and Phrases: graph colouring; average distance; average distance colouring
For a finite network, represented as a graph G = (V, E) with average distance (G), the average distance colouring of G is a function c from V to the set of non-negative integers, such that for any v ? V, |c(v) ? c(u)| ? 1 for all u ? V such that d(u, v) ? ??. In this paper, we find the average distance colouring number of some special types of networks and present a greedy algorithm to colour any graph with average distance colouring constraint. 2025, Diogenes Co. Ltd.. All rights reserved.
International Journal of Applied Mathematics;Volume;38;Issue;2s;pp.682-694
https://doi.org/10.12732/ijam.v38i2s.109 https://www.scopus.com/pages/publications/105017179082?origin=resultslist
Pandey P., CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Joseph M., CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India
Cancer survivors; Existential gratitude; Mortality; Post-traumatic growth; Spirituality
Cancer survivorship is often accompanied by existential distress as individuals confront mortality and search for meaning in their experiences. This study examines existential gratitude, which is a heightened appreciation of life shaped by suffering and impermanence, as a mediator between spirituality and post-traumatic growth (PTG) among Indian cancer survivors. Grounded in Terror Management Theory (TMT), this research explores how spirituality, rather than directly fostering PTG, requires existential gratitude as a transformative mechanism. A sample of 118 Indian cancer survivors, at least six months post-active treatment, participated in the study. Spearmans rho correlations revealed significant positive associations between existential gratitude, spirituality, and PTG. Mediation analysis demonstrated that existential gratitude fully mediated the relationship between spirituality and PTG (? = .16, p = .003), with spirituality showing no direct effect on PTG (? = .08, p = .414) when existential gratitude was introduced. These findings challenge traditional views of spirituality as an inherent driver of growth, highlighting instead that PTG arises when existential gratitude transforms mortality awareness into an appreciation of lifes fragility. 2025, Layah Liz Jacob, Anuradha Sathiyaseela.
Jacob, Layah Liz; Sathiyaseelan, Anuradha
All Open Access; Gold Open Access; Green Open Access
https://doi.org/10.12681/psy_hps.40933 https://www.scopus.com/pages/publications/105022875439?origin=resultslist
Jacob L.L., Department of Psychology, CHRIST University, India; Sathiyaseelan A., Department of Psychology, CHRIST University, India
Trauma, Ontological Exile, and the Trans Self: Reading Transgender Autobiographical Narratives from the Global South
autobiographical narratives; ontological exile; politics of unbelonging; transgender existential displacement; transgender trauma
Scholarly understanding of exile usually foregrounds the forced displacement of human beings from one geographical location to another due to war, violence, or fear of persecution. However, exile is also a psychological state of being caused by external factors that need not necessarily be limited to the physicality of dislodgement from a sense of home. This paper explores exile as an ontological condition informed by experiences of trauma, selfhood, and marginalisation from the vantage point of transgender lived experiences from India. The philosophical engagement of these ideas is exemplified by the autobiographical work of a transgender woman, A. Revathi, titled The Truth About Me: A Hijra Life Story. The paper facilitates dialogues between narrativising trauma, psychological exile, and the trans self-using interdisciplinary frameworks of Paul Ilie, Maurice Merleau-Ponty, Edward W. Said, Judith Butler, Cathy Caruth, Sara Ahmed, and Shoshana Felman to examine the interconnection between thoughts on trauma, testimony, inner exile, lived experiences, queer phenomenology, and gender performativity. The study observes that the reclamation of transgender selfhood emerges through the act of self-narration. It also reimagines exile and trauma as philosophical processes of self-awareness and becoming. 2025, University of Western Macedonia. All rights reserved.
Vineshkumar, Vineetha Anitha; Dazo, Kekhronguu
https://doi.org/10.12681/dia.43470 https://www.scopus.com/pages/publications/105027078333?origin=resultslist
Vineshkumar V.A., Department of English and Cultural Studies, CHRIST University, Bengaluru, India; Dazo K., Department of English and Cultural Studies, CHRIST University, Bengaluru, India
Development of carbonaceous anode battery materials from cornstalk and their electrochemical characterization using cyclic voltammetry
Anode materials; Biomass-derived carbon; Carbonaceous materials; Cobalt oxide; Cyclic voltammetry; Energy storage; Nickel oxide
This paper presents a study on the development of carbonaceous battery anode material derived from biomass sources, particularly cornstalk for energy storage applications. The carbonization process was optimized, followed by activation and doping with transition metal oxides like nickel and cobalt to enhance the electrochemical performance of the anode material. Cyclic voltammetry and chronopotentiometry studies were employed to characterize the electrochemical properties, specifically the charge storage behavior of the synthesized materials. Fourier transform infrared spectroscopy spectrum, BrunauerEmmettTeller analysis, and scanning electron microscopy were employed to study the impact of doping, surface area, pore size distribution, and surface morphology. The results indicate that doping with metal oxides significantly improves the conductivity and charge storage capacity of the carbon-based materials, making them promising candidates for sustainable battery applications. The Author(s) 2025.
Journal of Engineering and Applied Science;Volume;72;Issue;1;Article No.;100;
https://doi.org/10.1186/s44147-025-00658-0 https://www.scopus.com/pages/publications/105009984516?origin=resultslist
Xavier L.F., Department of Mechanical and Automobile Engineering, CHRIST University, Karnataka, Bangalore, 560074, India
Measuring autonomy in hybrid work: scale development
Autonomy in work; Hybrid workplace; India; Information Technology Industry; Scale development
Background: Autonomy is a core element in many established management theories, consistently linked to positive employee outcomes. However, the COVID-19 pandemic and rapid technological advancements have transformed workplace dynamics, particularly in the information technology (IT) sector in India, where hybrid work models have gained prominence. Despite this shift, no standardized measure exists to assess the autonomy experienced by employees in hybrid work environments, hindering deeper analysis and understanding. Objective: This study aims to contextualize, develop, and validate the Autonomy in Hybrid Work Scale (AHWS) for the Indian context, providing a tool for researchers and practitioners to systematically examine the impact of autonomy in hybrid work. Methods: A descriptive two-phase study was conducted following DeVelliss scale development framework. Phase 1 focused on conceptualizing and developing the construct through a comprehensive literature review, item generation, and assessment of content and face validity by experts, followed by a pilot test. Phase 2 encompassed the scale validation process, which included Exploratory Factor Analysis (EFA) to identify the underlying factor structure and Confirmatory Factor Analysis (CFA) to validate the model and assess its fit. Results: The data collected from 313 IT employees working in Bengaluru, India, was analyzed to confirm data normality (below 2.58). The items showed a strong and positive correlation (r =.734) with the Work Design Questionnaire which indicated convergent validity. Discriminant validity was confirmed through Fornell-Larcker and Heterotrait-Monotrait (HTMT) criteria, with HTMT values below 0.90. The final analysis yielded an 18-item scale with a Cronbachs alpha of 0.825, comprising four distinct dimensions: (a) work location autonomy, (b) work time autonomy, (c) work scheduling autonomy, and (d) work decision autonomy. Implications: The AHWS offers a valuable tool for both managers and academics to assess how different forms of autonomy influence employee well-being and productivity in hybrid work settings. It also addresses a gap in the literature, providing a foundation for further empirical research on autonomy in hybrid work models. The Author(s) 2025.
Datta, Pallavi; Balasundaram, Sathiyaseelan; N, Elangovan; Nair, Sridevi
Psicologia: Reflexao e Critica;Volume;38;Issue;1;Article No.;8;
Springer Science and Business Media Deutschland GmbH
https://doi.org/10.1186/s41155-025-00338-1 https://www.scopus.com/pages/publications/105001165192?origin=resultslist
Datta P., School of Business and Management, Christ University, Karnataka, Bengaluru, 560029, India; Balasundaram S., School of Business and Management, Christ University, Karnataka, Bengaluru, 560029, India; N E., School of Business and Management, Christ University, Karnataka, Bengaluru, 560029, India; Nair S., School of Business and Management, Christ University, Karnataka, Bengaluru, 560029, India
Is your phone ruining your well-being? Exploring the role of phubbing and mobile phone usage addiction on the well-being of users
A-C-E framework; Mobile phone addiction; Need Satisfaction; Phubbing behaviour; Self Determination theory; Well Being
Background: The consumption of mobile screen time is increasing day by day. When a person engages with the mobile phone for an extended period of time, it depicts addiction and escapes from the surroundings, leading to phubbing behavior. Therefore, this study investigates mobile phone addiction and how phubbing behavior affects psychological well-being. In addition, this paper examines the moderating role of self-determination theory in the aforesaid relationship. Methods: To examine the cause-and-effect relationship among the examined variables, PLS-SEM is used as a statistical tool for analysis. The data was collected from 450 participants via a survey through mall-intercept method, using a non-probability purposive sampling technique. Results: The results exhibited that mobile phone addiction is a significant determinant of phubbing behavior and well-being. The results also indicated that phubbing behavior negatively influences the well-being of the mobile phone user. It was also found that need satisfaction theory moderated the relationship between mobile phone usage, phubbing behavior, and well-being. The role of gender and time spent on mobile phones as control variables was also found to be significant. Originality: This current study offers insights into mobile phone addiction, phubbing behavior, and well-being, offering theoretical and practical implications fordigitalhealth, underpinned by the need satisfaction theory on the mobile phone user. The Author(s) 2026.
BMC Psychology;Volume;14;Issue;1;Article No.;415;
https://doi.org/10.1186/s40359-026-04143-y https://www.scopus.com/pages/publications/105034456205?origin=resultslist
Baber P., Symbiosis Law School, Symbiosis International Deemed University Pune, Noida, India; Baber R., School of Business & Management, Christ University, Karnataka, Bengaluru, India
Mediating role of resilience on the relationship between meta emotions and emotional regulation among neglected adolescents
Emotional Regulation; Meta emotions; Neglected adolescents; Resilience
Background: Adolescence is a pivotal stage in human development, marked by significant biological, cognitive, and emotional transformations that shape an individual's character and future behaviour. The emotional strategies and behavioural patterns inculcated during this phase become integral aspects of one's personality, influencing how one navigates through various life challenges. For vulnerable adolescents, such as neglected children in institutional care or orphans, negative life experiences can heighten the risk of developing psychological concerns. This heightened vulnerability is often exacerbated by impaired emotional regulation and low resilience, which may contribute to the emergence of internalising disorders. Methods: The present study was conducted to examine the relationship between meta emotions and difficulties in emotional regulation among neglected adolescents and to analyse the mediating effect of resilience on this relationship. The participants of the study were 667 neglected adolescents: 335 males (50.2%) and 332 females (49.8%) who belong to the age group 13 to 17years (mean age = 14.60, S.D = 1.16) years from various institutional homes across Bangalore. Results: The results of this study confirm that in the presence of increased levels of negative meta emotions in an individual, despite the mediating effects of resilience, difficulties in emotional regulation will be further worsened. This was substantiated by the positive correlation between negative meta emotion and difficulties in emotional regulation. Contrastingly, elevated positive meta emotions in an individual, along with the mediating effects of resilience, reduce the difficulties in emotional regulation. This was also reinforced by the strong relationship between positive meta emotions and difficulties in emotion regulation. Conclusion: The findings of the study highlight the prevalence of increased negative meta emotions and poor emotional regulation among neglected adolescents, which is of utmost importance from a psychological, social and policy-making perspective. This calls for the need for tailored and individual-focused interventional strategies to improve the psychological health of these vulnerable children. Moreover, the critical period of adolescence is a crucial time for implementing effective policies in order to shape the behavioural and cognitive aspects of personality with much-needed care, support, and professional guidance. The Author(s) 2025.
Jesline, Joshy; Romate, John; Diya, Elizabeth; Rajkumar, Eslavath
BMC Psychology;Volume;13;Issue;1;Article No.;622;
https://doi.org/10.1186/s40359-025-02856-0 https://www.scopus.com/pages/publications/105007449281?origin=resultslist
Jesline J., Department of Psychology, CHRIST University, Hosur Road, Karnataka, Bengaluru, 560029, India; Romate J., Department of Psychology, Central University of Karnataka, Kalaburagi, India; Diya E., Department of Psychology, CHRIST University, Hosur Road, Karnataka, Bengaluru, 560029, India; Rajkumar E., Department of Liberal Arts, Indian Institute of Technology (IIT), Bhilai, India
Sexual harassment complaints across BSE100 companies: a longitudinal dataset (20132023)
Behavioural trends; Bombay stock exchange; Disciplinary proceedings; Internal complaints committee; Sexual harassment; Workplace misconduct
Objective: This dataset offers empirical support for understanding the number of sexual harassment complaints across various industries and sectors, and for analysing patterns over a decade. The data was manually collected from the annual integrated report or business responsibility report of each company on the BSE100 list. This dataset can be utilised by the Indian Ministry of Women & Child Development and related stakeholders as a foundation for studying the impact of previous interventions and policy changes on complaint reporting rates. Additionally, it can also be used to analyse patterns and trends and give way to revisions to existing legal frameworks and improvements to grievance redressal mechanisms for sexual harassment complaints. Data description: Data includes descriptive statistics for all variables and compares complaints received between each year and the subsequent year, with a total of 10 year-to-year comparisons for the period: 20132024. The variables are: (1) List of BSE100 Companies, (2) Industry, (3) Sector, (4) Number of sexual harassment complaints received for the periods: 20132024, (5) Number of sexual harassment complaints pending during the periods: 20132024. The Author(s) 2025.
BMC Research Notes;Volume;18;Issue;1;Article No.;227;
https://doi.org/10.1186/s13104-025-07294-0 https://www.scopus.com/pages/publications/105005979891?origin=resultslist
R D., School of Law Christ (Deemed to be) University, Bangalore, India; Nath V G.R., School of Law Christ (Deemed to be) University, Bangalore, India
The role of psychological capital in shaping climate anxiety across generations
Climate anxiety; Environmental identity theory; Generational differences; Psychological capital; Resilience; Self-efficacy
Background: Climate change has transitioned from a distant environmental issue to an immediate psychological reality that profoundly affects how individuals perceive their future and well-being. This study investigates generational differences in climate anxiety and examines the role of psychological capital (PsyCap) as a potential protective resource through the lens of Environmental Identity Theory (EIT). Methods: A cross-sectional survey was conducted among 384 participants in Kerala, India, comprising Generation X (33.6%), Millennials (29.9%), and Generation Z (36.5%). Climate anxiety was measured using the Climate Anxiety Scale (Clayton & Karazsia, 2020), and PsyCap was assessed through the PCQ-12, encompassing hope, efficacy, resilience, and optimism. Data were analyzed using ANOVA and multiple regression, with effect sizes and confidence intervals reported. Results: Significant generational differences emerged for both cognitiveemotional impairment (F(2,381) = 3.83, p =.023) and functional impairment (F(2,381) = 6.15, p =.002). Gen Z reported significantly higher anxiety levels than Millennials (p =.045, d = ? 0.29*) and Gen X (p =.011, d = ? 0.35*). Regression analyses indicated that PsyCap and generation jointly predicted cognitiveemotional (R = 0.04, p =.008) and functional impairments (R = 0.056, p =.001), with self-efficacy emerging as a significant negatively associated with functional impairment (B = ? 0.12, p =.043). Conclusion: Gen Z experiences greater emotional and functional impacts of climate anxiety compared to older cohorts, while self-efficacy offers a modest buffering effect for functional impairment. These findings underscore the need for interventions that strengthen psychological resources and adaptive coping to mitigate climate-related distress among younger populations. The Author(s) 2026.
Kappan, Elsa; Thiagarajan, Vijayalaya Srinivas
Discover public health;Volume;23;Issue;1;Article No.;251;
https://doi.org/10.1186/s12982-026-01580-3 https://www.scopus.com/pages/publications/105030993046?origin=resultslist
Kappan E., Department of Psychology, CHRIST (Deemed to be University, Karnataka, Bengaluru, India; Thiagarajan V.S., Department of Psychology, CHRIST (Deemed to be University, Karnataka, Bengaluru, India
Addressing quarter life crisis as a public health priority
Developmental crisis; Public health; Quarter life crisis; SDG 3; Young adults
The Quarter-Life Crisis (QLC), a period of intense self-doubt, anxiety, and identity confusion during early adulthood has become a widespread phenomenon affecting mental health and well-being globally. In the Indian context, this phase is further shaped by cultural expectations, economic uncertainty, and social transitions that shape young adults sense of purpose and stability. Although often discussed in psychological and sociological terms, the QLC remains under-addressed in public health discourse. This perspective paper argues for the recognition of QLC as a legitimate public health issue with cross-sector implications. Economic precarity, including unstable employment, student debt, and housing insecurity, plays a critical role in exacerbating this crisis, making it not only a psychological experience but also a condition influenced by broader socioeconomic and cultural forces. Drawing on developmental psychology, sociocultural theory, and the framework of the Sustainable Development Goals (SDGs), this paper situates the Quarter-Life Crisis within Indias evolving social landscape and examines it as a social determinant of mental health. It further highlights community-based and digital interventions, such as resilience and self-compassion apps, that can support young adults. Integrating QLC into public health frameworks particularly those focused on Good Health and Well-Being (SDG 3) can offer timely, systemic solutions to a rising mental health concern among Indias youth and the global young adult population. The Author(s) 2026.
Glenda, Fernandes; Rajan, Aiswarya Vaderiyattil
Discover public health;Volume;23;Issue;1;Article No.;239;
https://doi.org/10.1186/s12982-026-01557-2 https://www.scopus.com/pages/publications/105030693604?origin=resultslist
Glenda F., CHRIST University, Bengaluru, India; Rajan A.V., CHRIST University, Bengaluru, India
Impact of job stress and work-life balance on turnover intention among Indian healthcare workers
Healthcare; Job stress; Turnover intentions; Work-life balance
The Healthcare sector is widely regarded as a high-stress-inducing environment, with considerable studies examining job stress and work-life balance in the healthcare sector since the COVID-19 pandemic. While these factors are well-documented, there is a growing need to shift the focus towards rising turnover rates within the industry post-pandemic. With this background, the study aims to examine the impact of job stress and work-life balance on turnover intentions among doctors by delving deeper into the dimensions of these variables and probing the effect of demographics on these variables. The proposed research employed a quantitative design to gather data from 127 healthcare doctors using purposive sampling. The data for this study were collected through an online Google form designed with three validated scales, which comprised doctors from diverse specializations and years of experience. The findings revealed that time stress significantly impacts work interference with personal life (WIPL) and personal life interference with work (PLIW). Personal life interference with work (PLIW) emerged as the strongest determinant of turnover intentions. Further, a greater psychological strain was encountered among female doctors than their male counterparts, implying that gender also had a potential influence on the outcome of the study. As a result, the study offers recommendations that can guide the retention strategies in healthcare organizations and promote a healthier and sustainable workforce. The Author(s) 2026.
Prabhu, Samhita; Thomas, Princy; Singh, Haobijam Brijesh
Discover public health;Volume;23;Issue;1;Article No.;140;
https://doi.org/10.1186/s12982-026-01426-y https://www.scopus.com/pages/publications/105029352141?origin=resultslist
Prabhu S., Christ University, Bengaluru, India; Thomas P., Christ University, Bengaluru, India; Singh H.B., Christ University, Bengaluru, India
Awareness and perception of adolescent boys about menstruation: an exploratory study from rural India
Adolescent boys; Focus group discussion; Gender-inclusive education; Menstrual awareness; Menstrual hygiene management; Menstrual taboos; Menstruation; Thematic analysis
Background/objectives: Menstruation, despite being a natural process, remains stigmatized in many patriarchal societies, where taboos and misinformation perpetuate silence and misconceptions. This study investigates adolescent boys awareness and perceptions of menstruation in rural India, examining the influence of cultural, educational, and social factors on their understanding. Methods: Employing an exploratory qualitative design, a focus group discussion (FGD) was conducted with eight 15-year-old boys from a rural secondary school in Kerala, India. The session was audio-recorded and supplemented with detailed field notes to capture verbal and non-verbal insights. Braun and Clarkes thematic analysis framework was used to identify key themes. Results: Three primary themes emerged: Levels of awareness (ranging from correct but insufficient to lack), Sources of knowledge (media, peers, cultural practices), and Desire for further knowledge. Findings indicate that fragmented or inaccurate knowledge, shaped by cultural and societal norms, reinforces stereotypes and stigma around menstruation. Conclusions: Findings underscore the need for inclusive and culturally sensitive educational interventions for boys, aimed at dispelling myths and fostering empathy. Such programs can contribute to improved awareness, reduced stigma, and greater support for menstrual hygiene management (MHM) practices. Future research should assess similar interventions across broader contexts to determine their impact on challenging menstrual taboos. The Author(s) 2025.
Discover public health;Volume;22;Issue;1;Article No.;205;
https://doi.org/10.1186/s12982-025-00600-y https://www.scopus.com/pages/publications/105003857781?origin=resultslist
Abraham D.M., Department of Psychology, University of Calicut, Calicut University (P.O.), Kerala, Malappuram, 673635, India, Christ University, Karnataka, Bangalore, 560029, India; Saliha F.B., Department of Psychology, University of Calicut, Calicut University (P.O.), Kerala, Malappuram, 673635, India, Farook College (Autonomous), P.O. Farook College, Kerala, Kozhikode, 673632, India
We just keep pushing through: a mixed-method study on musculoskeletal discomfort and mental well-being among nurses in resource-limited settings
Healthcare policy; Mixed methods; Musculoskeletal discomfort; Nursing workforce; Occupational health; Well-being
Background: Nurses in under-resourced settings frequently report high levels of musculoskeletal (MSK) discomfort, which significantly affects their mental well-being. While workplace strain is well documented, the combined impact of physical burden and institutional neglect remains underexplored in these environments. Aim: The study aims to examine the prevalence of MSK discomfort and its association with psychological well-being among nurses in under-resourced healthcare environments in Northeast India, and to explore the experiential and structural factors contributing to these occupational health risks. Methods: A sequential mixed-methods study design was employed, following an explanatory approach. The study commenced with a survey to gather quantitative data. Quantitative data were collected from 216 nurses using the Extended Nordic Musculoskeletal Questionnaire (Extended-NMQ) and the WHO-5 Well-Being Index, the results of which informed the development of subsequent interview questions. Semi-structured interviews were then conducted with 11 nurses to capture experiential and structural factors. This structure enabled deeper contextual understanding and facilitated triangulation across data types. Results: Among the participants, 47.2% reported experiencing lower back pain, followed by discomfort in the knees (27.3%) and upper back (25%). Higher levels of MSK discomfort were significantly associated with employment in the public sector and more than ten years of work experience. A strong negative correlation was observed between MSK discomfort and mental well-being. Thematic analysis revealed key stressors: physical depletion, emotional exhaustion, organizational apathy, and limited healthcare access. In response to these challenges, nurses often relied on self-management due to insufficient institutional support. Triangulated findings underscored how structural deficiencies intensified both physical and psychological strain among nurses. Conclusions: There is an urgent need for evidence-based occupational health interventions to address ergonomic, psychosocial, and institutional challenges, particularly in low-resource healthcare settings, to safeguard the well-being of frontline nursing staff. This study offers novel understanding from a high-need yet under-researched geographic context, namely the northeastern states of India, bridging empirical gaps in MSK health literature through the integration of experiential and structural factors. Clinical trial number: Not applicable. The Author(s) 2025.
Patangia, Bishal; Srinivasan, Priyadarshini Moharkonda; Lee, Michelle Chin Chin
BMC Nursing;Volume;24;Issue;1;Article No.;1301;
https://doi.org/10.1186/s12912-025-03698-2 https://www.scopus.com/pages/publications/105019378394?origin=resultslist
Patangia B., School of Psychological Sciences, Christ University, Bangalore, India; Srinivasan P.M., School of Psychological Sciences, Christ University, Bangalore, India; Lee M.C.C., School of Psychology, Massey University, Level 3, Albany Village Library Building, Kell Drive, Auckland, 0632, New Zealand
An in vitro slow-growth callus conservation strategy for several medicinal plants using response surface methodology and machine learning
Antioxidant capacity; Citric acid; In vitro conservation; Methyl jasmonate; Plant cell culture; Response surface methodology
Background: In vitro culture of callus is an effective method for conserving the genetic resources of economically important crops. However, continuous subculturing is a costly and labor-intensive process. Therefore, establishing an efficient in vitro long-term conservation system applicable to various plant species is required. In this study, calli derived from five medicinal plant species, Camellia japonica (Cj), Centella asiatica (Ca), Ligusticum afficinale (Lo), Panax ginseng (Pg), and Sageratia thea (St) were used to optimize storage conditions and establish a suitable in vitro conservation strategy. Calli cultures were maintained on the appropriate culture medium at 5C for 120 days. Cell viability and regrowth rate were assessed during the storage period, and correlations between growth and antioxidant traits were examined. Subsequently, pretreatment optimization using sucrose (39%), MeJA (0-200 M), and CTR (020mg/L) was performed using RSM, and the effects of pretreatment and storage temperature on callus conservation were evaluated. In addition, machine learning models such as GRNN, MLP, RF, SVR, and XGBoost were applied to the experimental data. Results: The findings demonstrated that, in comparison to Ca and St, Lo, Pg, and Cj exhibited noticeably higher antioxidant capacity while maintaining high cell viability and regrowth rates. Interestingly, Ca and St drastically decreased viability and regrowth after 60 days, whereas Lo, Pg, and Cj maintained viability and regeneration for up to 90 days. Both TPC and AC (measured by FRAP assay) showed a high positive correlation with cell viability and growth rate, according to correlation analysis. RSM predicted that the optimal pretreatment medium for enhancing antioxidant capacity was the species-specific proliferation medium supplemented with 3% sucrose, 135 M MeJA, and 20mg/L CTR, while the highest TSSC was achieved using the species-specific proliferation medium supplemented with 9% sucrose and 200 M MeJA. When the storage temperature was set to 15C following the antioxidant-enhancing pretreatment derived from the RSM optimization, all five species showed improved cell viability and regrowth rates, among the storage methods. Among the ML models tested, XGBoost demonstrated the most stable and accurate predictive performance for both viability and regrowth during in vitro conservation. SHAP-based analysis of the XGBoost model, focusing on regrowth rate, revealed that storage duration was the most influential factor affecting regrowth prediction, followed by storage temperature, while pretreatment conditions showed secondary but meaningful contributions. Conclusions: This study demonstrates that long-term callus conservation is closely associated with AC and TPC. Medium supplemented with sucrose 3%, 135 M MeJA, and 20mg/L CTR, followed by storage at 15C, significantly improved viability and regrowth, and calli could be maintained up to 120 days without subculturing. This approach provides an efficient and broadly applicable in vitro strategy for the conservation of diverse plant genetic resources. The Author(s) 2026.
Kim, Ye-Won; Lee, Han-Sol; Murthy, Hosakatte Niranjana; Lee, Hyoshin; Park, So-Young
BMC Biotechnology;Volume;26;Issue;1;Article No.;49;
https://doi.org/10.1186/s12896-026-01129-x https://www.scopus.com/pages/publications/105036335427?origin=resultslist
Kim Y.-W., Department of Horticultural Science, Division of Animal, Horticultural and Food Sciences, Chungbuk National University, Cheongju, 28644, South Korea; Lee H.-S., Department of Horticultural Science, Division of Animal, Horticultural and Food Sciences, Chungbuk National University, Cheongju, 28644, South Korea; Murthy H.N., Department of Horticultural Science, Division of Animal, Horticultural and Food Sciences, Chungbuk National University, Cheongju, 28644, South Korea, Department of Life Sciences, Christ University, Bengaluru, 560029, India; Lee H., Department of Horticultural Science, Division of Animal, Horticultural and Food Sciences, Chungbuk National University, Cheongju, 28644, South Korea; Park S.-Y., Department of Horticultural Science, Division of Animal, Horticultural and Food Sciences, Chungbuk National University, Cheongju, 28644, South Korea
Comprehensive transcriptomic and functional characterization of protoplast regeneration in Angelica gigas Nakai
Angelica gigas; Cell identity transition; Protoplast regeneration; Stem cell; Totipotency; Transcriptional transition
Background: Protoplasts that are isolated from various plant sources, including leaf mesophyll tissue, callus, will continue to have the ability to take part in cell wall regeneration, division, and expression of totipotency. In model systems like Arabidopsis thaliana, it has been thoroughly established. Meanwhile, the fate of protoplasts isolated from both embryogenic (EC) and non-embryogenic callus (NEC) in other plants is unknown. Thus, we conducted transcriptome analyses of protoplasts produced from both EC and NEC in Angelica gigas in the present investigation. To achieve this, three stages of RNA sequencing were carried out: (1) EC, (2) freshly isolated protoplasts (Pt), and (3) cells undergoing cell division (CD) during A. gigas in vitro protoplast regeneration. Different gene expression programs were identified across stages through transcriptome profiling, which highlighted early stress responses, transcriptional changes, and the acquisition of stem cell identity following protoplast isolation. Results: A pre-existing stem cell-like condition was shown by the strong expression of WUSCHEL-RELATED HOMEOBOX5 (WOX5) and CUP-SHAPED COTYLEDON2 (CUC2) genes at the EC stage. Important genes linked to stress reactions and cellular transcriptional changes, as WOX13 and WOUND INDUCED DEDIFFERENTIATION1 (WIND1), were significantly elevated at the Pt stage. Additionally, during this phase, genes associated with the cell cycle, auxin and cytokinin signaling, and cell wall regeneration were also active, indicating a dynamic shift toward regaining stem cell identity. Key regulators of stem cell maintenance and proliferation, such as LATERAL ORGAN BOUNDARIES DOMAIN16 (LBD16) and ENHANCER OF SHOOT REGENERATION2 (ESR2), were then substantially expressed at the CD stage, encouraging the start of cell division. The dynamic regulation of embryogenesis-related genes, including SOMACTIC EMBRYOGENESIS RECEPTOR-LIKE KINASE 2 (SERK2), LBD29, ESR2, LBD16, D-TYPE CYCLINS (CYCD3-2), and WOX1, during protoplast culture was validated by real-time quantitative polymerase chain reaction (RT-qPCR). Conclusions: WOX5 and CUC2 genes were found to be significantly expressed at the EC stage, suggesting a pre-existing stem cell-like state. Important genes linked to stress reactions and cellular transcriptional changes, as WOX13 and WIND1, were clearly elevated at the Pt stage. The activation of genes linked to cell wall renewal, auxin and cytokinin signaling, and the cell cycle during this phase also suggested a dynamic transition toward regaining stem cell identity. Additionally, the findings previously reported show that the EC-derived protoplasts successfully underwent cell division and contributed to the development of somatic embryos. Although the NEC-generated protoplasts did not divide upon culture, these results show that embryogenic cells maintain their embryogenic potential even after protoplast isolation and culture. The Author(s) 2026.
Lee, Han-Sol; Han, Jong-Eun; Shim, Donghwan; Choi, Bae Young; Cho, Hyunwoo; Murthy, Hosakatte Niranjana; Park, So-Young
BMC Plant Biology;Volume;26;Issue;1;Article No.;208;
https://doi.org/10.1186/s12870-025-08075-4 https://www.scopus.com/pages/publications/105029171322?origin=resultslist
Lee H.-S., Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea; Han J.-E., Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea; Shim D., Department of Biological Sciences, Chungnam National University, Daejeon, 34134, South Korea; Choi B.Y., Department of Biological Sciences, Chungnam National University, Daejeon, 34134, South Korea, School of Liberal Arts and Sciences, Korea National University of Transportation, Chungju, 27469, South Korea; Cho H., Department of Industrial Plant Science and Technology, Chungbuk National University, Cheongju, 28644, South Korea; Murthy H.N., Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea, Department of Life Sciences, Christ University, Central Campus, Bengaluru, 560029, India; Park S.-Y., Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea