Mediating and moderating variables of employee relations and sustainable organizations: a systematic literature review and future research agenda
Conceptual framework; Employee relations; Mediating variables; Moderating variables; Sustainable organizations
Purpose: This study aims to perform a systematic literature review to organize the abundance of information on employee relations (ER) and sustainable organizations. Moreover, this study identifies the research gaps by investigating the review of ER mediating and moderating variables and the relationship between ER and sustainable organizations. Design/methodology/approach: This study is based on the systematic literature review methodology involving 257 studies in the final stage. The Scopus and Google Scholar databases with search criteria employee relations and employee relations and sustainable organization were used to achieve the research objective. After applying inclusion and exclusion criteria, researchers come to the distribution of the articles based on the subthemes, geographical region, types of methods, top authors with affiliation and complete research articles based on the citation. In the final stage, this study concluded with the conceptual model comprising mediators and moderators of ER as well as the mediating and moderating variables of the relationship between ER and sustainable organizations. Findings: The reviewed literature shows that employee relation is an optimal strategy for retaining employees via proper disclosure of human resources (HRs) and ER Index. This study included the top six publishers, namely, Emerald, Elsevier, Sage, Springer, Taylor and Francis and Wiley Online Library, to do an exhaustive review on a specific topic. The findings indicate that after COVID-19, the ER index, HR disclosures and the sustainability of ER are among the new and required paradigm shifts needed to manage a crisis impact and perform productively. The mediator and moderator variables that can improve employeeemployer relationships are organizational trusts, organizational justice, perceived job satisfaction, organizational structure and firm ownership. On the other hand, variables that mediate and moderate the relationship between ER and sustainable organizations are organizational climate, organization trust, organization culture, perceived organization support, psychological empowerment, firm ownership, leadership behavior and attitude, respectively. The findings concluded that harmonious and cordial ER are pertinent in building sustainable organizations and accomplishing organizational goals. Practical implications: The mediating and moderating variables that have been identified can be helpful for enthusiastic researchers in contributing to empirical research. Practitioners and managers can use the findings in making an effective organizational model that develops good employeeemployer relationships and helps create a culture of trust and harmony. This study focuses on exploring the variables of ER, which strengthens employeeemployer relationships and supports organizations to stay agile and attain sustainability to endure in the future. Originality/value: This study insights on the specific mediating and moderating variables of ER and sustainable organizations. Till date, studies exploring constructs of ER and sustainable organizations are still in deficit. Better employee relation reflects and leads to a more resilient organization. Future researchers should explore the connection between pandemics and ER which is done insufficiently in the present time. 2022, Emerald Publishing Limited.
Yadav R.; Chaudhary N.S.; Kumar D.; Saini D.
International Journal of Organizational Analysis, Vol-31, No. 7, pp. 3023-3050.
https://doi.org/10.1108/IJOA-12-2021-3091 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85136016705&doi=10.1108%2fIJOA-12-2021-3091&partnerID=40&md5=b847b62f0043357cad00a414fed6466a
Yadav R., School of Business and Management, CHRIST (Deemed to be University), Bangalore, India; Chaudhary N.S., Soil School of Business Design, Gurugram, India; Kumar D., Department of Management Studies, Delhi College of Technology and Management, Palwal, India; Saini D., Indian Institute of Management, Raipur, India
Comprehensive understanding of biomedical usages of metal and non metal doped carbon dots
Biomedical applications; Carbon dots; Doping; Nitrogen-carbon dots
In recent years, carbon dots have garnered significant attention, particularly within the biomedical realm, owing to their exceptional characteristics. The unique attributes of carbon dots can be further enhanced through the introduction of heteroatom via doping. Various techniques have been devised by researchers to facilitate the doping of carbon dots, with both metallic and non-metallic elements. Elements such as nitrogen (81%), sulfur (67%), and silicon (64.1%) have been successfully employed for doping carbon dots leading to heightened quantum yields. This review compiles the diverse methodologies and elements employed in doping of carbon dots, and their applications in the biomedical domain in recent times. This review discusses the uses of doped carbon dots, both metal and non-metal-doped variants, elucidating their manifold utilities in various biomedical sectors, notably bioimaging, wound healing, and cancer therapy. The discussion culminates by addressing present challenges and offering insights into future prospects of doped carbon dots. 2023 Elsevier Ltd
Mathew A.; Varghese A.; Devi K.R. S.; Pinheiro D.
https://doi.org/10.1016/j.mtcomm.2023.106991 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85170412455&doi=10.1016%2fj.mtcomm.2023.106991&partnerID=40&md5=dbbd05d4426c8daf473a6f1fc05ecfc1
Mathew A., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Varghese A., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Devi K.R. S., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Pinheiro D., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India
Stability Analysis and Navigational Techniques of Wheeled Mobile Robot: A Review
dynamic analysis; kinematic analysis; navigation; path planning; WMR
Wheeled mobile robots (WMRs) have been a focus of research for several decades, particularly concerning navigation strategies in static and dynamic environments. This review article carefully examines the extensive academic efforts spanning several decades addressing navigational complexities in the context of WMR route analysis. Several approaches have been explored by various researchers, with a notable emphasis on the inclusion of stability and intelligent capabilities in WMR controllers attracting the attention of the academic community. This study traces historical and contemporary WMR research, including the establishment of kinetic stability and the construction of intelligent WMR controllers. WMRs have gained prominence in various applications, with precise navigation and efficient control forming the basic prerequisites for their effective performance. The review presents a comprehensive overview of stability analysis and navigation techniques tailored for WMRs. Initially, the exposition covers the basic principles of WMR dynamics and kinematics, explaining the different wheel types and their associated constraints. Subsequently, various stability analysis approaches, such as Lyapunov stability analysis and passivation-based control, are discussed in depth in the context of WMRs. Starting an exploration of navigation techniques, the review highlights important aspects including path planning and obstacle avoidance, localization and mapping, and trajectory tracking. These techniques are carefully examined in both indoor and outdoor settings, revealing their benefits and limitations. Finally, the review ends with a comprehensive discussion of the current challenges and possible routes in the field of WMR. The discourse includes the fusion of advanced sensors and state-of-the-art control algorithms, the cultivation of more robust and reliable navigation strategies, and the continued exploration of novel WMR applications. This article also looks at the progress of mobile robotics during the previous three decades. Motion planning and path analysis techniques that work with single and multiple mobile robots have been discussed extensively. One common theme in this research is the use of soft computing methods to give mobile robot controllers cognitive behaviors, such as artificial neural networks (ANNs), fuzzy logic control (FLC), and genetic algorithms (GAs). Nevertheless, there is still a dearth of applications for mobile robot navigation that leverage nature-inspired algorithms, such as firefly and ant colony algorithms. Remarkably, most studies have focused on kinematics analysis, with a small number also addressing dynamics analysis. 2023 by the authors.
Borkar K.K.; Aljrees T.; Pandey S.K.; Kumar A.; Singh M.K.; Sinha A.; Singh K.U.; Sharma V.
Multidisciplinary Digital Publishing Institute (MDPI)
https://doi.org/10.3390/pr11123302 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85180667057&doi=10.3390%2fpr11123302&partnerID=40&md5=bd8fcd0c2718c1d839a07ab75af9e0e3
Borkar K.K., Department of Industrial & Production Engineering, School of Studies of Engineering & Technology, GGV, Bilaspur, 495001, India; Aljrees T., Department College of Computer Science and Engineering, University of Hafr Al-Batin, Hafar Al-Batin, 39524, Saudi Arabia; Pandey S.K., Department of Computer Engineering & Applications, GLA University, Mathura, 281406, India; Kumar A., Department of Computer Engineering & Applications, GLA University, Mathura, 281406, India; Singh M.K., Department of Industrial & Production Engineering, School of Studies of Engineering & Technology, GGV, Bilaspur, 495001, India; Sinha A., Department of Computer Science and Information Technology, IGNOU, New Delhi, 110001, India; Singh K.U., School of Computing, Graphic Era Hill University, Dehradun, 248002, India; Sharma V., Computer Science Department, CHRIST (Deemed to be University), Delhi-NCR Campus, Ghaziabad, 201204, India
Synthesis, mechanisms, challenges, and future prospects of Ti3C2 MXene and its heterojunctions for photocatalytic dye degradation efficiency: a comprehensive review
2D material; Co-catalyst; Degradation; Dye; MXene; Nanocomposite; Photocatalysis; S-Scheme; Z-Scheme
In recent years, significant attention has been given to developing novel two-dimensional (2D) materials, including MXenes. Titanium carbide (Ti3C2) is one such MXene with a bandgap ranging from 0.92 eV to 1.75 eV. MXenes possess unique physical and chemical properties that make them useful in various applications, including electrocatalysis, supercapacitors, semiconductors, batteries, sensing, biomedicine, water splitting, and photocatalysis. Research on environmental photocatalysis has focused on enhancing properties such as high conductivity, structural stability, and morphology. However, a single catalytic material may not be sufficient to achieve high catalytic efficiency. Hence, there is a need to modify MXenes. This review provides an overview of the various synthesis methods of MXene and their remarkable properties. It also discusses recent advances in MXene composites and catalytic mechanisms for dye degradation. To improve the catalytic performance of MXene, a heterojunction and Schottky junction are proposed. 2023 Elsevier Ltd
Mathew S.; Ramachandra M.; Devi K R S.; Pinheiro D.; Manickam S.; Pang C.H.; Sonawane S.H.
https://doi.org/10.1016/j.mtsust.2023.100568 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85175182399&doi=10.1016%2fj.mtsust.2023.100568&partnerID=40&md5=4466fa9c8abb6139bb7bf38a902242a4
Mathew S., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Ramachandra M., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Devi K R S., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Pinheiro D., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Manickam S., Petroleum and Chemical Engineering, Faculty of Engineering, Universiti Teknologi Brunei, Bandar Seri Begawan, BE1410, Brunei Darussalam; Pang C.H., Department of Chemical and Environmental Engineering, University of Nottingham Ningbo China, Ningbo, 315100, China; Sonawane S.H., Chemical Engineering Department, National Institute of Technology, Telangana State, Warangal, 506 004, India
Short-chain fatty acid: An updated review on signaling, metabolism, and therapeutic effects
Anticancer; antidiabetic; antioxidant; HDAC inhibition; SCFAs
Fatty acids are good energy sources (9 kcal per gram) that aerobic tissues can use except for the brain (glucose is an alternative source). Apart from the energy source, fatty acids are necessary for cell signaling, learning-related memory, modulating gene expression, and functioning as cytokine precursors. Short-chain fatty acids (SCFAs) are saturated fatty acids arranged as a straight chain consisting minimum of 6 carbon atoms. SCFAs possess various beneficial effects like improving metabolic function, inhibiting insulin resistance, and ameliorating immune dysfunction. In this review, we discussed the biogenesis, absorption, and transport of SCFA. SCFAs can act as signaling molecules by stimulating G protein-coupled receptors (GPCRs) and suppressing histone deacetylases (HDACs). The role of SCFA on glucose metabolism, fatty acid metabolism, and its effect on the immune system is also reviewed with updated details. SCFA possess anticancer, anti-diabetic, and hepatoprotective effects. Additionally, the association of protective effects of SCFA against brain-related diseases, kidney diseases, cardiovascular damage, and inflammatory bowel diseases were also reviewed. Nanotherapy is a branch of nanotechnology that employs nanoparticles at the nanoscale level to treat various ailments with enhanced drug stability, solubility, and minimal side effects. The SCFA functions as drug carriers, and nanoparticles were also discussed. Still, much research was not focused on this area. SCFA functions in host gene expression through inhibition of HDAC inhibition. However, the study has to be focused on the molecular mechanism of SCFA against various diseases that still need to be investigated. 2022 Taylor & Francis Group, LLC.
Rekha K.; Venkidasamy B.; Samynathan R.; Nagella P.; Rebezov M.; Khayrullin M.; Ponomarev E.; Bouyahya A.; Sarkar T.; Shariati M.A.; Thiruvengadam M.; Simal-Gandara J.
Critical Reviews in Food Science and Nutrition, Vol-64, No. 9, pp. 2461-2489.
ISSN: 10408398; PubMed ID: 36154353; CODEN: CRFND
Rekha K., Department of Environmental and Herbal Science, Tamil University, Tamil Nadu, Thanjavur, India; Venkidasamy B., Department of Oral and Maxillofacial Surgery, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Tamil Nadu, Chennai, India; Samynathan R., R&D Division, Alchem Diagnostics, Tamil Nadu, Coimbatore, India; Nagella P., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, India; Rebezov M., Department of Scientific Research, V. M. Gorbatov Federal Research Center for Food Systems, Moscow, Russian Federation, Department of Scientific Research, Russian State Agrarian UniversityMoscow Timiryazev Agricultural Academy, Moscow, Russian Federation, Department of Scientific Research, K. G. Razumovsky Moscow State University of technologies and management (The First Cossack University), Moscow, Russian Federation; Khayrullin M., Department of Scientific Research, K. G. Razumovsky Moscow State University of technologies and management (The First Cossack University), Moscow, Russian Federation; Ponomarev E., Department of Scientific Research, K. G. Razumovsky Moscow State University of technologies and management (The First Cossack University), Moscow, Russian Federation; Bouyahya A., Laboratory of Human Pathologies Biology, Faculty of Sciences, Mohammed V University in Rabat, Rabat, Morocco; Sarkar T., Department of Food Processing Technology, Malda Polytechnic, West Bengal State Council of Technical Education, Government of West Bengal, West Bengal, Malda, India; Shariati M.A., Department of Scientific Research, Russian State Agrarian UniversityMoscow Timiryazev Agricultural Academy, Moscow, Russian Federation, Department of Scientific Research, K. G. Razumovsky Moscow State University of technologies and management (The First Cossack University), Moscow, Russian Federation; Thiruvengadam M., Department of Crop Science, College of Sanghuh Life Sciences, Konkuk University, Seoul, South Korea; Simal-Gandara J., Analytical Chemistry and Food Science Department, Faculty of Science, Universidade de Vigo, Nutrition and Bromatology Group, Ourense, Spain
Recent advances in the development, design and mechanism of negative electrodes for asymmetric supercapacitor applications
Asymmetric supercapacitor; charging-discharging; nanoparticles; negative electrodes; specific capacitance
Continuous technical advancements in a variety of industries, such as portable electronics, transportation, green energy, are frequently hampered by the inadequacy of energy-storage technologies. Asymmetric supercapacitors can expand their operating voltage window past the thermodynamic breakdown voltage of electrolytes by utilizing two distinct electrode materials, providing a workaround for the symmetric supercapacitors energy storage constraints. This evaluation offers a thorough understanding of this area. To comprehend the extensive research done in this field, we first examine the fundamental energy-storage mechanisms and performance evaluation standards for asymmetric supercapacitors. The most recent developments in the design and manufacture of electrode materials as well as the general structure of asymmetric supercapacitors. We have also discussed a number of significant scientific issues and offer our opinions on how to improve the electrochemical properties of future asymmetric energy storage devices. First, methods for designing high-performance electrode materials for supercapacitors must be developed; next, controllably built supercapacitor types must be attained (such as symmetric capacitors including double-layer and pseudocapacitors, asymmetric capacitors, and Li-ion capacitors). This review is timely because of the rapid expansion of research in this area. It summarizes recent developments in the study and creation of high-performance electrode materials with high supercapacitors. A number of crucial topics for enhancing the energy density of supercapacitors are examined, along with some reciprocal correlations between the main impacting parameters. Difficulties and prospects in this fascinating field are also covered. This offers a fundamental understanding of supercapacitors and serves as a crucial design rule for enhanced next-generation supercapacitors that will be used in both industrial and consumer applications. In this context, we extensively reviewed the classification of supercapacitor, EDLC (activated carbon, carbon aerogel, carbon nanotube), Pseudocapacitors, conducting polymers, metal oxides, hybrid materials, composite hybrids, rechargeable batteries, asymmetric devices and its design, aqueous solid state, fiber based asymmetric device, graphene based asymmetric device, terminologies used during the electrode selection, positive and negative electrodes in asymmetric device, material used for fabrication of negative electrodes, electrochemical performance of various devices which are fabricated by different electrode materials. Performance of material for various asymmetric device applications, conclusions outlook, recent developments in asymmetric devices. The current review may offer a thorough understanding and future prospects for developing negative electrodes to enhance asymmetric supercapacitor performance. 2023 Taylor & Francis Group, LLC.
Vandana M.; Bijapur K.; Soman G.; Hegde G.
Critical Reviews in Solid State and Materials Sciences, Vol-49, No. 3, pp. 335-370.
Vandana M., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, India, Centre for Advanced Research and Development (CARD), CHRIST (Deemed to be University), Bangalore, India; Bijapur K., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, India, Centre for Advanced Research and Development (CARD), CHRIST (Deemed to be University), Bangalore, India; Soman G., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, India, Centre for Advanced Research and Development (CARD), CHRIST (Deemed to be University), Bangalore, India; Hegde G., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, India, Centre for Advanced Research and Development (CARD), CHRIST (Deemed to be University), Bangalore, India
Extrinsic pseudocapacitance: Tapering the borderline between pseudocapacitive and battery type electrode materials for energy storage applications
Batteries; Energy storage; Extrinsic pseudocapacitance; Hybrid energy storage devices; Pseudocapacitance; Supercapacitor
Extrinsic pseudocapacitance, which can also be referred to as induced pseudocapacitance, is, at present, one of the most widely explored fields in energy storage. Extrinsic pseudocapacitive mechanism can be imparted to an otherwise diffusion-controlled faradaic energy storage material by external methods like size engineering, compositional modification, doping, anion intercalation, and morphological modifications. As a significant mechanism that plays a borderline role between battery-type and pseudocapacitive nature of energy storage, extrinsic pseudocapacitance tends to narrow down the boundary between these conventionally diverse systems, which in turn would contribute a lot to the development of hybrid energy storage technologies. For effective utilization in upcoming energy storage technologies, a critical analysis on the effect of this mechanism on reported devices shall turn into a valid account. This review gives a detailed insight into extrinsic pseudocapacitance, its significance, and recently reported materials, methods, and devices. The future outlook and challenges in transforming extrinsic pseudocapacitive mechanisms into a promising strategy for next-generation energy storage devices are also discussed. 2023 Elsevier Ltd
https://doi.org/10.1016/j.est.2023.109292 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85174438814&doi=10.1016%2fj.est.2023.109292&partnerID=40&md5=e84fc3edd5e662961738992ebad2a4d8
George J., Department of Physics and Electronics, Christ (Deemed To Be University), Bangalore, 560029, India; Balachandran M., Department of Physics and Electronics, Christ (Deemed To Be University), Bangalore, 560029, India
A Comprehensive Review on the Antimicrobial and Photocatalytic Properties of Green Synthesized Silver Nanoparticles
antibacterial; antimicrobial; green synthesis; photocatalysis; silver nanoparticles
With the advancement of technology, there is a growing demand for new nanoparticles that are viable, eco-friendly, non-toxic, and non-hazardous, as well as having unique chemical and physical properties. Silver nanoparticles are currently promising for antibacterial, antimicrobial, and photocatalytic applications. Because of their toxicity, nanosilver particles are now widely used in various applications, including cosmetics, clothing, sunscreen, medicinal, sensing, antibacterial, antimicrobial, and photocatalytic. The importance of plant extracts in the synthesis of AgNPs is emphasized. The various mechanisms and characterization techniques used in the study of silver nanoparticles will also be covered. This review also discusses the role of green synthesized AgNPs in antimicrobial and photocatalytic applications, which adds to our understanding of improving health, and the environment and preventing contagious diseases. 2022 by the authors.
Narayanaswamy S.; Bhaskar R.; Jayadevappa R.K.K.; Ramachandran S.K.M.; Prasad M.A.
Letters in Applied NanoBioScience, Vol-12, No. 4
https://doi.org/10.33263/LIANBS124.140 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85151958470&doi=10.33263%2fLIANBS124.140&partnerID=40&md5=54318f0ec590b38ac7acd50f3d1be812
Narayanaswamy S., Department of Physics, RV Institute of Technology and Management, Bengaluru, 560 076, India; Bhaskar R., Department of Life Sciences, Christ (Deemed to be University), Hosur Road, Bengaluru, 560 029, India; Jayadevappa R.K.K., Department of Chemistry, RV Institute of Technology and Management, Bengaluru, 560 076, India; Ramachandran S.K.M., Department of Physics, RV Institute of Technology and Management, Bengaluru, 560 076, India; Prasad M.A., Department of Physics, Dayananda Sagar College of Engineering, Kumaraswamy Layout, Karnataka, Bangalore, 560 078, India
Biopolymers as promising vehicles for drug delivery to the brain
biopolymers; Blood brain barrier; drug targeting; neuroprotection; therapeutics
The brain is a privileged organ, tightly guarded by a network of endothelial cells, pericytes, and glial cells called the blood brain barrier. This barrier facilitates tight regulation of the transport of molecules, ions, and cells from the blood to the brain. While this feature ensures protection to the brain, it also presents a challenge for drug delivery for brain diseases. It is, therefore, crucial to identify molecules and/or vehicles that carry drugs, cross the blood brain barrier, and reach targets within the central nervous system. Biopolymers are large polymeric molecules obtained from biological sources. In comparison with synthetic polymers, biopolymers are structurally more complex and their 3D architecture makes them biologically active. Researchers are therefore investigating biopolymers as safe and efficient carriers of brain-targeted therapeutic agents. In this article, we bring together various approaches toward achieving this objective with a note on the prospects for biopolymer-based neurotherapeutic/neurorestorative/neuroprotective interventions. Finally, as a representative paradigm, we discuss the potential use of nanocarrier biopolymers in targeting protein aggregation diseases. 2023 Informa UK Limited, trading as Taylor & Francis Group.
Drug Metabolism Reviews, Vol-56, No. 1, pp. 46-61.
ISSN: 3602532; PubMed ID: 37955126; CODEN: DMTRA
Mythri R.B., Department of Psychology, Christ (Deemed to be University), Dharmaram College Post, Karnataka, Bengaluru, India; Aishwarya M.R.B., Department of Engineering, University of Strathclyde, Glasgow, United Kingdom
Greener Assembly of Nano Catalysts and Sustainable Applications of Magnetically Retrievable and Plasmonic Nano Catalysts
Green synthesis; Magnetically retrievable; Nano catalysts; Nanocomposite; Plasmonic
Since ages, catalysts have played a pivotal role in accelerating the production and lowering the cost of a plethora of industrially important commodities. The latest in the scenario are nanocatalysts, which offer a wide array of advantages ranging from improved reaction rates to higher rates of recyclability. However, factors such as stability and support systems must be fine-tuned to achieve maximum efficiency. In accordance with the principle of sustainability, green synthesis methods have propelled the development of a range of nanocatalysts that can be applied in various domains, such as the food industry and biofuel production. Simultaneously, heterogeneous catalysis is gaining more attention globally, primarily due to the ease of recoverability of the nanocatalysts and in this context, magnetically retrievable nanocatalysts are indeed a boon for the green synthesis and sustainable production. Nanocomposites combining plasmonic and catalytic components with noble metal nanoparticles (Au and Ag) and doped semiconductor nanostructures have gained interest in recent years owing to their utility in multiple sectors by virtue of their ability to convert sunlight to chemical energy. The current review describes some methods for the synthesis of such nanocatalysts and their applications in diverse domains. Graphical Abstract: (Figure presented.) The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023.
Sridhar A.; Sunil C.K.; Sarkar R.; Sarojini S.
Topics in Catalysis, Vol-67, No. 45748, pp. 265-279.
Sridhar A., Department of Life Sciences, CHRIST (Deemed to Be University), Bangalore, India; Sunil C.K., Department of Life Sciences, CHRIST (Deemed to Be University), Bangalore, India; Sarkar R., Department of Life Sciences, CHRIST (Deemed to Be University), Bangalore, India; Sarojini S., Department of Life Sciences, CHRIST (Deemed to Be University), Bangalore, India
Bioactive compounds from Cordyceps and their therapeutic potential
Bioactive compounds; C. militaris; Cordycepin; Cordyceps sinesis; Himalayan viagra; Keeda Jadi
The Clavicipitaceae familys largest and most diverse genus is Cordyceps. They are most abundant and diverse in humid temperate and tropical forests and have a wide distribution in: Europe, North America, and East and Southeast Asian countries, particularly: Bhutan, China, Japan, Nepal, Korea, Thailand, Vietnam, Tibet, and the Himalayan region of India, and Sikkim. It is a well-known parasitic fungus that feeds on insects and other arthropods belonging to 10 different orders. Over 200 bioactive metabolites, that include: nucleotides and nucleosides, polysaccharides, proteins, polypeptides, amino acids, sterols, and fatty acids, among others have been extracted from Cordyceps spp. demonstrating the phytochemical richness of this genus. These components have been associated with a variety of pharmacological effects, including: anti-microbial, anti-apoptotic, anti-cancer, anti-inflammatory, antioxidant, and immunomodulatory activities. In this paper, the bioactivity of various classes of metabolites produced by Cordyceps spp., and their therapeutic properties have been reviewed in an attempt to update the existing literature. Furthermore, one of its nucleoside and a key bioactive compound, cordycepin has been critically elaborated with regard to its biosynthesis pathway and the recently proposed protector-protmechanism as well as various biological and pharmacological effects, such as: suppression of purine and nucleic acid biosynthesis, induction of apoptosis, and cell cycle regulation with their mechanism of action. This review provides current knowledge on the bioactive potential of Cordyceps spp. 2023 Informa UK Limited, trading as Taylor & Francis Group.
Critical Reviews in Biotechnology, Vol-44, No. 5, pp. 753-773.
ISSN: 7388551; PubMed ID: 37518188; CODEN: CRBTE
Krishna K.V., Applied and Industrial Biotechnology Laboratory, Christ (Deemed-to-be University), Karnataka, Bangalore, India; Ulhas R.S., Institute of Biochemistry and Biophysics, Faculty of Life Sciences, University of Jena (Friedrich-Schiller-Universit Jena), Jena, Germany; Malaviya A., Applied and Industrial Biotechnology Laboratory, Christ (Deemed-to-be University), Karnataka, Bangalore, India, Division of Life Sciences, Gyeongsang National University, Gyeongsangnam-do, South Korea, QuaLife Biotech Pvt Ltd, Bangalore, India
Anthocyanin Production from Plant Cell and Organ Cultures In Vitro
anthocyanins; colorants; elicitation; metabolic engineering; plant cell cultures; secondary metabolites
Anthocyanins are water-soluble pigments found in plants. They exist in various colors, including red, purple, and blue, and are utilized as natural colorants in the food and cosmetics industries. The pharmaceutical industry uses anthocyanins as therapeutic compounds because they have several medicinal qualities, including anti-obesity, anti-cancer, antidiabetic, neuroprotective, and cardioprotective effects. Anthocyanins are conventionally procured from colored fruits and vegetables and are utilized in the food, pharmaceutical, and cosmetic industries. However, the composition and concentration of anthocyanins from natural sources vary quantitively and qualitatively; therefore, plant cell and organ cultures have been explored for many decades to understand the production of these valuable compounds. A great deal of research has been carried out on plant cell cultures using varied methods, such as the selection of suitable cell lines, medium optimization, optimization culture conditions, precursor feeding, and elicitation for the production of anthocyanin pigments. In addition, metabolic engineering technologies have been applied for the hyperaccumulation of these compounds in varied plants, including tobacco and arabidopsis. In this review, we describe various strategies applied in plant cell and organ cultures for the production of anthocyanins. 2023 by the authors.
Murthy H.N.; Joseph K.S.; Paek K.Y.; Park S.-Y.
All Open Access; Gold Open Access; Green Open Access
https://doi.org/10.3390/plants13010117 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85182177725&doi=10.3390%2fplants13010117&partnerID=40&md5=26314728f6c1b7245cf605bb45ff8360
Murthy H.N., Department of Botany, Karnatak University, Dharwad, 580003, India, Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea; Joseph K.S., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, 560029, India; Paek K.Y., Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea; Park S.-Y., Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea
Bioreactor configurations for adventitious root culture: recent advances toward the commercial production of specialized metabolites
Adventitious roots; airlift bioreactors; bubble column bioreactors; cell cultures; organ cultures; scale-up process; specialized metabolites; stirred tank bioreactors
In vitro plant cell and organ cultures are appealing alternatives to traditional methods of producing valuable specialized metabolites for use as: pharmaceuticals, food additives, cosmetics, perfumes, and agricultural chemicals. Cell cultures have been adopted for the production of specialized metabolites in certain plants. However, in certain other systems, adventitious roots are superior to cell suspension cultures as they are organized structures that accumulate high levels of specialized metabolites. The cultivation of adventitious roots has been investigated in various bioreactor systems, including: mechanically agitated, pneumatically agitated, and modified bioreactors. The main relevance and importance of this work are to develop a long-lasting industrial biotechnological technology as well as to improve the synthesis of these metabolites from the plant in vitro systems. These challenges are exacerbated by: the peculiarities of plant cell metabolism, the complexity of specialized metabolite pathways, the proper selection of bioreactor systems, and bioprocess optimization. This reviews major objective is to analyze several bioreactor types for the development of adventitious roots, as well as the advantages and disadvantages of each type of bioreactor, and to describe the strategies used to increase the synthesis of specialized metabolites. This review also emphasizes current advancements in the field, and successful instances of scaled-up cultures and the generation of specialized metabolites for commercial purposes are also covered. 2023 Informa UK Limited, trading as Taylor & Francis Group.
Murthy H.N.; Joseph K.S.; Paek K.Y.; Park S.Y.
Critical Reviews in Biotechnology, Vol-44, No. 5, pp. 837-859.
Murthy H.N., Department of Botany, Karnatak University, Dharwad, India, Department of Horticultural Science, Chungbuk National University, Cheongju, South Korea; Joseph K.S., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, India; Paek K.Y., Department of Horticultural Science, Chungbuk National University, Cheongju, South Korea; Park S.Y., Department of Horticultural Science, Chungbuk National University, Cheongju, South Korea
Origin, ecotoxicity, and analytical methods for microplastic detection in aquatic systems
Analytical methods; Aquatic ecosystem; Challenges and bottlenecks; Characterization; Microplastics; Toxicity
Over the decades, interaction of microplastics with other pollutants in a dynamic environmental set up was observed to increase their toxic effects. This scenario is worse in aquatic environments due to the entry of huge loads of microplastic components into the waterbodies through direct plastic dumping and those delivered from effluents originating from various treatment plants. Although extensive research was done to understand the issue associated with microplastic contamination of various aquatic environments, a huge research gap still exists in areas like their ecotoxicology, fate, distribution, and detection methods in aquatic environments. Moreover, the combined deleterious effect of microplastics in association with other environmental pollutants is not widely studied and requires more research focus. The major scope of this review is to present a comprehensive outlook on the recent studies carried out to understand the types, origin, distribution, transport, fate, and toxicity of microplastics in aquatic environments, both fresh water and marine. The review summarizes the ecotoxicological effects of microplastic contaminants in aquatic environment like the oxidative damage, neurotoxicity and decreased reproductive potential. An in-depth discussion regarding the ability of the microplastics in combination with other pollutants to serve as potentially hazardous agents in aquatic environment is also elaborated in the review. Further a summary on various microplastic detection methods, challenges associated with microplastic detection and management is carefully reviewed and compiled in this work. The need for proper awareness programs to general public highlighting the toxicity of microplastics and strict regulations regarding their continuous assessment and management in waterbodies are essential factors in controlling their adverse effect on aquatic environment. 2023 Elsevier B.V.
Kumar V.; Umesh M.; Chakraborty P.; Sharma P.; Sarojini S.; Basheer T.; Kaur K.; Pasrija R.; Barcelo D.
TrAC - Trends in Analytical Chemistry, Vol-170
https://doi.org/10.1016/j.trac.2023.117392 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85179130183&doi=10.1016%2fj.trac.2023.117392&partnerID=40&md5=a0ad0de11608ef742fd33a767ca126a1
Kumar V., Bioconversion and Tissue Engineering Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602105, India; Umesh M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Chakraborty P., School of Allied Healthcare and Sciences, Jain (Deemed to be University), Whitefield, Karnataka, Bangalore, 560066, India; Sharma P., Department of Biochemistry, Maharshi Dayanand University, Rohtak, India; Sarojini S., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Basheer T., Waste Management Division, Integrated Rural Technology Centre (IRTC), Mundur, Kerala, Palakkad, 678592, India; Kaur K., Punjab Agricultural University, Institute of Agriculture, Punjab, Gurdaspur, 143521, India; Pasrija R., Department of Biochemistry, Maharshi Dayanand University, Rohtak, India; Barcelo D., Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research, IDAEA-CSIC, Jordi Girona, 18-26, Barcelona, 08034, Spain, Sustainability Cluster, School of Engineering, UPES, Dehradun, India
Review on the fish collagen-based scaffolds in wound healing and tissue engineering
Fish Collagen; In vivo studies; Scaffolds; Tissue Regeneration; Wound healing
Collagen from marine organisms is an emerging source in tissue engineering, an alternative to bovine and porcine collagen. Despite the positive results on wound healing from fish collagen scaffolds, the comprehension and advancements in its properties are limited. Given this context, this study aimed to carry out a systematic review to examine the effects of collagen scaffolds on different models of experimental skin wounds, the advantages and its limitations. The search was conducted according to the orientations of Preferred Reporting Items for Systematic review and Meta-Analysis (PRISMA) and the MeSH (Medical Subject Healings) terms used were Fish Collagen AND Wound Healing AND Scaffold. 36 articles in total were sorted out from the databases of Google Scholar and PubMed. After the analysis, the current review covers 10 articles from the beginning of 2017 to March 2023. The results are mainly focused on the different methods of collagen extraction, preparation of scaffolds and its treatment on the animal model along with its effects. To infer, this current review states that, despite the positive effects of collagen on tissue repair and regeneration, no product is available for medical purposes. Thus, this review also demonstrates the huge potential for collagen in tissue engineering. 2024 Visagaa Publishing House.
Meganathan G.; Balasubramanian B.; Meyyazhagan A.; Paul J.; Chaudhary A.; Pappuswamy M.
Natural Resources for Human Health, Vol-4, No. 1, pp. 1-23.
All Open Access; Hybrid Gold Open Access
https://doi.org/10.53365/nrfhh/175205 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85181529124&doi=10.53365%2fnrfhh%2f175205&partnerID=40&md5=e7b001442ca8a50e9519d04202e69bc0
Meganathan G., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, 560029, India; Balasubramanian B., Department of Food Science and Biotechnology, College of Life Sciences, Sejong University, Seoul, South Korea; Meyyazhagan A., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, 560029, India; Paul J., Department of Zoology, St. Josephs University, 36 Lalbagh Road, Karnataka, Bengaluru, India; Chaudhary A., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, 560029, India; Pappuswamy M., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, 560029, India
Production of biomass and bioactive compounds from cell and organ cultures of ginseng, He-shou-wu, purple coneflower, and St. John's wort for the use in cosmetic industry
Bioactive compounds; Bioreactors; Cosmeceuticals; Cosmetics; Scale-up process
Plants and their products have been utilized as raw materials in the preparation of cosmetics for millennia. Currently, research is being done to find new plant materials that may be used as ingredients in cosmetic preparations, including body sprays, shampoos, conditioners, hair dyes/sprays, and other cosmetics. The plants that are used in the preparation of cosmetic products are usually procured from nature, however, the quality and quantity of bioactive ingredients present in the biomass vary based on the species, environment, and geographical locations from where the material has been procured. In addition, procurement of plant material from natural resources may lead to a shortage of material and even endanger the status of rare plants in the natural environment. Therefore, there is increased interest in the use of plant cell, tissue, and organ cultures (PCTOC) for the production of raw materials and bioactive specialized metabolites. There is also scope for increasing the accumulation of biomass and bioactive compounds in PCTOC by adopting various strategies such as optimization of culture medium, culture environment, elicitation, and other bioprocess methods. Furthermore, PCTOC-produced raw materials are free from contaminants, pesticides, and heavy metals and an important benefit of producing biomass in vitro is that it is easily accepted by regulatory authorities and consumers. In the current review, we describe the bioactive compounds of ginseng, purple coneflower, He-shou-wu, and St. John's wort which have cosmetological importance. Additionally, we elucidate the PCTOC method adopted for the production of biomass and bioactive compounds in these plants. 2023 SAAB
South African Journal of Botany, Vol-164, pp. 334-344.
https://doi.org/10.1016/j.sajb.2023.12.007 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85179604803&doi=10.1016%2fj.sajb.2023.12.007&partnerID=40&md5=89c875025069a3ec0473c4cf79219f6a
Murthy H.N., Department of Botany, Karnatak University, Dharwad, 580003, India, Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea; Joseph K.S., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, 560029, India; Paek K.Y., Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea; Park S.Y., Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea
Prevalence of Cardiovascular Diseases in South Asians: Scrutinizing Traditional Risk Factors and Newly Recognized Risk Factors Sarcopenia and Osteopenia/Osteoporosis
One of the primary reasons for complications and death worldwide are cardiovascular diseases (CVDs), with a death toll of approximately 18 million per year. CVDs include cardiomyopathy, hypertension, ischemic heart disease, coronary heart disease, myocardial infarction, heart attack, hearth failure, etc. Over 80% of the CVD mortality is recorded from lower and middle-income countries. Records from the past decade have highlighted the increase of CVDs among the South Asian populations, and the prime purpose of the review is to jot down the reasons for the steep spike in CVDs. Studies analyzing the causative factors for the increase of CVDs in South Asians are still to be verified. Apart from known predisposing and lifestyle factors, other emerging risk factors associated with CVDs, namely the musculoskeletal diseases sarcopenia and osteopenia, should be tracked to tackle research gaps in upcoming analyses. This requires loads of scientific efforts. With proper monitoring, the raising alarm that the CVD burden generates can be reduced. This review discusses the already established signs and recognizes important clues to the emerging etiology of CVDs in the Asian population and prevention measures to keep it at bay. 2023 Elsevier Inc.
Kuchi Bhotla H.; Meyyazhagan A.; Pushparaj K.; Pappuswamy M.; Chaudhary A.; Arumugam V.A.; Balasubramanian B.; Ragu Varman D.; Orlacchio A.; Rengasamy K.R.R.
Current Problems in Cardiology, Vol-49, No. 1
https://doi.org/10.1016/j.cpcardiol.2023.102071 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85172758893&doi=10.1016%2fj.cpcardiol.2023.102071&partnerID=40&md5=0bb9765a72ab5224310af0e3f57af93f
Kuchi Bhotla H., Department of Life Science, CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Meyyazhagan A., Department of Life Science, CHRIST (Deemed to be University), Karnataka, Bengaluru, India, Dipartimento di Medicina e Chirurgia, Universitdi Perugia, Perugia, Italy; Pushparaj K., Department of Zoology, School of Biosciences, Avinashilingam Institute for Home Science and Higher Education for Women, Tamil Nadu, Coimbatore, India; Pappuswamy M., Department of Life Science, CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Chaudhary A., Department of Life Science, CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Arumugam V.A., Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, Coimbatore, India; Balasubramanian B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, South Korea; Ragu Varman D., Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA, United States; Orlacchio A., Laboratorio di Neurogenetica, Centro Europeo di Ricerca sul Cervello (CERC), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, Rome, Italy, Dipartimento di Medicina e Chirurgia, Universitdi Perugia, Perugia, Italy; Rengasamy K.R.R., Laboratory of Natural Products and Medicinal Chemistry (LNPMC), Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, India
Excited state intramolecular proton transfer dual emission Schiff bases for metal detection and cell imaging
cell imaging; dual emission; environmental monitoring; Fluorescent probes; Schiff base
Fluorescent probes incorporating the excited-state intramolecular proton transfer (ESIPT) phenomenon have emerged as versatile tools in scientific research. These probes exhibit dual emission, resulting from the unique transfer of a proton within the molecule upon excitation. This property makes ESIPT-based Schiff bases highly attractive for metal detection, cell imaging, and sensing biologically important molecules. In metal detection, the spectral changes of ESIPT-based Schiff bases upon interaction with metal ions enable the development of sensitive and selective sensors. For cell imaging, their photophysical properties make them ideal for labeling cellular components and facilitating multicolor imaging. In sensing biomolecules, ESIPT-based Schiff bases offer selective detection of interactions and enzymatic activities. Integration of these probes holds great promise for applications in environmental monitoring, biomedical research, and healthcare. This review focuses on the photoluminescent properties and application of ESIPT dual emission Schiff bases for sensing of metal ions, biologically relevant molecules and cell imaging. 2023 Taylor & Francis Group, LLC.
Applied Spectroscopy Reviews, Vol-59, No. 7, pp. 959-988.
Joy F., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India; Aakash V., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India; Devasia J., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India; Nizam A., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India
Carbon Dot-Based Fluorescence Resonance Energy Transfer (FRET) Systems for Biomedical, Sensing, and Imaging Applications
bio-imaging; carbon dots; environmental sensing; FRET; membrane dynamics; metal sensing
Carbon dots (CDs) emerge as a potential group of photo-luminescent nano-materials due to their excellent optical, electrical, and chemical properties, as well as their competence in a wide range of environmental applications. CDs have unique and appealing properties such as excellent stability, low toxicity, water solubility, and derivability. When coupled with CDs, fluorescence resonance energy transfer (FRET) results in the development of highly sensitive ratiometric fluorescence sensor probes with potential applications in bio-imaging, metal sensing, membrane dynamics, and environmental sensing. In this review, the progress and recent developments in CDs based FRET systems utilized for various environmental applications are conferred. An in-depth description is provided regarding the numerous donor/acceptor systems which when integrated with CDs generate efficient FRET systems. The review enables researchers to identify and develop specific systems which can be utilized to generate a FRET pair with potential physicochemical properties that aid the development of the same for various applications. 2023 Wiley-VCH GmbH.
Gopal A.R.; Joy F.; Dutta V.; Devasia J.; Dateer R.; Nizam A.
Particle and Particle Systems Characterization, Vol-41, No. 1
https://doi.org/10.1002/ppsc.202300072 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85174722877&doi=10.1002%2fppsc.202300072&partnerID=40&md5=7e4c80f22b3280cff9fa799f606d7a84
Gopal A.R., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bengaluru, 560029, India; Joy F., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bengaluru, 560029, India; Dutta V., Department of Chemistry, University Centre for Research and Development, Chandigarh University, Punjab, Mohali, 140413, India; Devasia J., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bengaluru, 560029, India; Dateer R., Centre for Nano and Material Science, Jain (Deemed to be University), Jain Global Campus, Jakkasandra Post, Karnataka, Ramanagara, Kanakapura, 562112, India; Nizam A., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bengaluru, 560029, India
Production of specialized metabolites in plant cell and organo-cultures: the role of gamma radiation in eliciting secondary metabolism
Elicitation; gamma rays; ionizing radiation; mutants; reactive oxygen species; secondary metabolites
Purpose: To provide an updated summary of recent advances in the application of gamma irradiation to elicit secondary metabolism and for induction of mutations in plant cell and organ cultures for the production of industrially important specialized metabolites (SMs). Conclusions: Research on the application of gamma radiation with plants has contributed a lot to microbial decontamination of seeds, and the promotion of physiological processes such as seed germination, seedling vigor, plant growth, and development. Various studies have demonstrated the influence of gamma rays on the morphology, physiology, and biochemistry of plants. Recent research efforts have also shown that low-dose gamma (5100 Gy) irradiation can be utilized as an expedient solution to alleviate the deleterious effect of abiotic stresses and to obtain better yields of plants. Inducing mutagenesis using gamma irradiation has also evolved as a better option for inducing genetic variability in crops, vegetables, medicinal and ornamentals for their genetic improvement. Plant SMs are gaining increasing importance as pharmaceutical, therapeutic, cosmetic, and agricultural products. Plant cell, tissue, and organ cultures represent an attractive alternative to conventional methods of procuring useful SMs. Among the varied approaches the elicitor-induced in vitro culture techniques are considered an efficient tool for studying and improving the production of SMs. This review focuses on the utilization of low-dose gamma irradiation in the production of high-value SMs such as phenolics, terpenoids, and alkaloids. Furthermore, we present varied successful examples of gamma-ray-induced mutations in the production of SMs. Copyright 2024 Taylor & Francis Group LLC.
International Journal of Radiation Biology, Vol-100, No. 5, pp. 678-688.
ISSN: 9553002; PubMed ID: 38451191; CODEN: IJRBA