A Review on Fish Skin-Derived Gelatin: Elucidating the Gelatin PeptidesPreparation, Bioactivity, Mechanistic Insights, and Strategies for Stability Improvement
applications; bio-functionality; characteristics; fish skin; gelatin; gelatin peptides; limitations; stability
Fish skin-derived gelatin has garnered significant attention recently due to its abundant availability and promising bioactive properties. This comprehensive review elucidates various intricacies concerning fish skin-derived gelatin peptides, including their preparation techniques, bioactive profiles, underlying mechanisms, and methods for stability enhancement. The review investigates diverse extraction methods and processing approaches for acquiring gelatin peptides from fish skin, emphasizing their impact on the peptide composition and functional characteristics. Furthermore, the review examines the manifold bioactivities demonstrated by fish skin-derived gelatin peptides, encompassing antioxidant, antimicrobial, anti-inflammatory, and anticancer properties, elucidating their potential roles in functional food products, pharmaceuticals, and nutraceuticals. Further, mechanistic insights into the functioning of gelatin peptides are explored, shedding light on their interactions with biological targets and pathways. Additionally, strategies aimed at improving the stability of gelatin peptides, such as encapsulation, modification, and integration into delivery systems, are discussed to extend the shelf life and preserve the bioactivity. Overall, this comprehensive review offers valuable insights into using fish skin-derived gelatin peptides as functional ingredients, providing perspectives for future research endeavors and industrial applications within food science, health, and biotechnology. 2024 by the authors.
Joy J.M.; Padmaprakashan A.; Pradeep A.; Paul P.T.; Mannuthy R.J.; Mathew S.
Multidisciplinary Digital Publishing Institute (MDPI)
https://doi.org/10.3390/foods13172793 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85203655048&doi=10.3390%2ffoods13172793&partnerID=40&md5=e94564c423f3a2e64b8006357c0255e9
Joy J.M., Biochemistry and Nutrition Division, ICAR-Central Institute of Fisheries Technology, Kerala, Cochin, 682029, India, Faculty of Marine Sciences, Cochin University of Science and Technology, Kerala, Cochin, 682022, India, Department of Zoology, St. Teresas College (Autonomous), Kerala, Ernakulam, 682011, India; Padmaprakashan A., Biochemistry and Nutrition Division, ICAR-Central Institute of Fisheries Technology, Kerala, Cochin, 682029, India, Faculty of Marine Sciences, Cochin University of Science and Technology, Kerala, Cochin, 682022, India, Department of Life Sciences, Christ University, Hosur Main Road, Bhavani Nagar, Karnataka, Bangalore, 560029, India; Pradeep A., Biochemistry and Nutrition Division, ICAR-Central Institute of Fisheries Technology, Kerala, Cochin, 682029, India, Faculty of Marine Sciences, Cochin University of Science and Technology, Kerala, Cochin, 682022, India; Paul P.T., Biochemistry and Nutrition Division, ICAR-Central Institute of Fisheries Technology, Kerala, Cochin, 682029, India, Faculty of Marine Sciences, Cochin University of Science and Technology, Kerala, Cochin, 682022, India; Mannuthy R.J., Biochemistry and Nutrition Division, ICAR-Central Institute of Fisheries Technology, Kerala, Cochin, 682029, India, Faculty of Marine Sciences, Cochin University of Science and Technology, Kerala, Cochin, 682022, India; Mathew S., Biochemistry and Nutrition Division, ICAR-Central Institute of Fisheries Technology, Kerala, Cochin, 682029, India
Emerging Nanomaterials as Versatile Nanozymes: A New Dimension in Biomedical Research
Bioimaging; Biomedical application; Biosensing; Carbon dots; Covalent organic framework; Metalorganic framework; Nanozymes
The enzyme-mimicking nature of versatile nanomaterials proposes a new class of materials categorized as nano-enzymes, ornanozymes. They are artificial enzymes fabricated by functionalizing nanomaterials to generate active sites that can mimic enzyme-like functions. Materials extend from metals and oxides to inorganic nanoparticles possessing intrinsic enzyme-like properties. High cost, low stability, difficulty in separation, reusability, and storage issues of natural enzymes can be well addressed by nanozymes. Since 2007, more than 100 nanozymes have been reported that mimic enzymes like peroxidase, oxidase, catalase, protease, nuclease, hydrolase, superoxide dismutase, etc. In addition, several nanozymes can also exhibit multi-enzyme properties. Vast applications have been reported by exploiting the chemical, optical, and physiochemical properties offered by nanozymes. This review focuses on the reported nanozymes fabricated from a variety of materials along with their enzyme-mimicking activity involving tuning of materials such as metal nanoparticles (NPs), metal-oxide NPs, metalorganic framework (MOF), covalent organic framework (COF), and carbon-based NPs. Furthermore, diverse applications of nanozymes in biomedical research are discussed in detail. The Author(s), under exclusive licence to Springer Nature Switzerland AG 2024.
Jacob E.; Mathew D.; Benny L.; Varghese A.
Topics in Current Chemistry, Vol-382, No. 3
Springer Science and Business Media Deutschland GmbH
Jacob E., Department of Chemistry, Christ University, Hosur Road, Bengaluru, 560029, India; Mathew D., Department of Chemistry, Christ University, Hosur Road, Bengaluru, 560029, India; Benny L., Department of Chemistry, Christ University, Hosur Road, Bengaluru, 560029, India; Varghese A., Department of Chemistry, Christ University, Hosur Road, Bengaluru, 560029, India
A rapid investigation of near-infrared (NIR) fluorescent switch-on probes for detection and in cellulo tracking of G-quadruplex and double-stranded DNA
This review provides a comprehensive overview of the recent advancements in Near Infrared (NIR) fluorescence switch-on probes designed for the detection and in cellulo tracking of G-quadruplex and double-stranded DNA (dsDNA). G-quadruplexes, non-canonical DNA structures, play pivotal roles in regulating various biological processes, making them critical targets for therapeutic and diagnostic applications. The unique properties of NIR fluorescence probes, such as deep tissue penetration, minimal photodamage, and low autofluorescence background, offer significant advantages for bioimaging. We critically analyze the design strategies, photophysical properties, and binding mechanisms of various NIR fluorescence switch-on probes. Additionally, we discuss their efficacy and specificity in identifying G-quadruplexes and dsDNA within cellular environments. Key challenges and future directions for improving the sensitivity, selectivity, and biocompatibility of these probes are also highlighted. This review aims to underscore the potential of NIR fluorescence probes in advancing our understanding of DNA dynamics and their applications in biomedical research. 2024 The Royal Society of Chemistry.
https://doi.org/10.1039/d4ra06207h https://www.scopus.com/inward/record.uri?eid=2-s2.0-85205460531&doi=10.1039%2fd4ra06207h&partnerID=40&md5=3c777d933a574f7f7f95bafabb28cf75
Shinziya H., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bangalore, 560029, India; Menon R.S., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bangalore, 560029, India; Das A.K., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bangalore, 560029, India
Nanomaterials as novel elicitors of pharmacologically active plant specialized metabolites in cell and organ cultures: current status and future outlooks
Cell cultures; Elicitor; Nanomaterials; Organ cultures
Specialized plant metabolites, such as phenolics, terpenes, terpenoids, nitrogen-containing compounds, and sulfur-containing compounds, are commercially valuable owing to their wide array of applications in the medical, pharmacological, cosmetic, agriculture, and food industries. Procuring valuable specialized metabolites from wild or cultivated plants is desirable; however, the concentrations and quality of secondary compounds vary between samples. Therefore, plant cells and organ cultures have been selected as viable alternatives for producing specialized metabolites. Elicitation is a strategy used to enhance the accumulation of specialized compounds in cell and organ cultures. Different biotic substances, including signaling chemicals such as salicylic acid and methyl jasmonate, elements of plant cell walls (cellulose and pectin), polysaccharides from microbes (chitin and glucan), and abiotic substances such as inorganic salts, heavy metals, UV radiation, and high salinity, have been successfully tested and used as elicitors for the hyperaccumulation of bioactive substances in cell and organ cultures. Recently, metals, metal oxide nanoparticles, and carbon-based nanomaterials have been used as unique elicitors to boost the synthesis of bioactive compounds in cell and organ cultures. The applications and usage of nanoparticles as elicitors in plant cell and organ cultures are summarized in this review. The mechanism of elicitation, toxicity, benefits, and drawbacks of using nanoparticles in plant cell and organ cultures are discussed. Graphical abstract: (Figure presented.) The Author(s), under exclusive licence to Springer Nature B.V. 2023.
Murthy H.N.; Joseph K.S.; Paek K.Y.; Park S.Y.
Plant Growth Regulation, Vol-104, No. 1, pp. 5-30.
Springer Science and Business Media B.V.
Murthy H.N., Department of Botany, Karnatak University, Dharwad, 580003, India, Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea; Joseph K.S., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, 560029, India; Paek K.Y., Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea; Park S.Y., Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea
Mapping the literature on school bullying in India: A scoping review
Bullying; Cyberbullying; India; Schools; Scoping review
School bullying has been identified as a major issue among students throughout the world. With around 260 million school students, the largest student population in the world, it becomes essential to investigate this issue in the Indian context. The present work uses the Arksey and O'Malley (2005) framework for scoping review to examine the nature of research on school bullying in India and identify research gaps to be addressed by future research. The review maps the concepts examined, research approaches used, sample characteristics, data collection methods, researcher characteristics, and nature of publications in relation to bullying. Seven databases - JSTOR, PsycNET, Cochrane Reviews, ERIC, MEDLINE, Web of Science, and Cochrane Central Register for Controlled Trials - were searched for sources containing the terms bullying and India published in English and between the years 2015 and 2022. Thirty-eight sources selected for the review suggest that existing research in India on school bullying is limited compared to the West and yet provides a guiding light to future researchers. The findings from this review highlight research gaps in the existing literature and outline areas for further exploration. 2024 Elsevier Ltd
https://doi.org/10.1016/j.avb.2024.101978 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85197395351&doi=10.1016%2fj.avb.2024.101978&partnerID=40&md5=0ecd51ee5d8505a4f52520df2120f829
Suresh S., Department of Psychology, CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Vijaya R., Department of Psychology, CHRIST (Deemed to be University), Karnataka, Bengaluru, India
Developmental prospects of carrageenan-based wound dressing films: Unveiling techno-functional properties and freeze-drying technology for the development of absorbent films A review
Advanced wound dressings; Biodegradable dressings; Carrageenan biocomposites; Freeze-drying techniques; Wound healing process
This review explores the intricate wound healing process, emphasizing the critical role of dressing material selection, particularly for chronic wounds with high exudate levels. The aim is to tailor biodegradable dressings for comprehensive healing, focusing on maximizing moisture retention, a vital element for adequate recovery. Researchers are designing advanced wound dressings that enhance techno-functional and bioactive properties, minimizing healing time and ensuring cost-effective care. The study delves into wound dressing materials, highlighting carrageenan biocomposites superior attributes and potential in advancing wound care. Carrageenan's versatility in various biomedical applications demonstrates its potential for tissue repair, bone regeneration, and drug delivery. Ongoing research explores synergistic effects by combining carrageenan with other novel materials, aiming for complete biocompatibility. As innovative solutions emerge, carrageenan-based wound-healing medical devices are poised for global accessibility, addressing challenges associated with the complex wound-healing process. The exceptional physico-mechanical properties of carrageenan make it well-suited for highly exudating wounds, offering a promising avenue to revolutionize wound care through freeze-drying techniques. This thorough approach to evaluating the wound healing effectiveness of carrageenan-based films, particularly emphasizing the development potential of lyophilized films, has the potential to significantly improve the quality of life for patients receiving wound healing treatments. 2024 Elsevier B.V.
Amruth P.; Akshay P.; Rosemol Jacob M.; Joy J.M.; Mathew S.
International Journal of Biological Macromolecules, Vol-276
ISSN: 1418130; PubMed ID: 38992537; CODEN: IJBMD
https://doi.org/10.1016/j.ijbiomac.2024.133668 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198581517&doi=10.1016%2fj.ijbiomac.2024.133668&partnerID=40&md5=f3497478739ed27b63ed5bdc9731e43d
Amruth P., Biochemistry and Nutrition Division, ICAR-Central Institute of Fisheries Technology, Kerala, Cochin, 682029, India, Faculty of Marine Sciences, Cochin University of Science and Technology, Kerala, Cochin, 682022, India, Department of Life Sciences, Christ University, Hosur Main Road, Bhavani Nagar, Karnataka, Bangalore, 560029, India; Akshay P., Biochemistry and Nutrition Division, ICAR-Central Institute of Fisheries Technology, Kerala, Cochin, 682029, India, Faculty of Marine Sciences, Cochin University of Science and Technology, Kerala, Cochin, 682022, India; Rosemol Jacob M., Biochemistry and Nutrition Division, ICAR-Central Institute of Fisheries Technology, Kerala, Cochin, 682029, India, Faculty of Marine Sciences, Cochin University of Science and Technology, Kerala, Cochin, 682022, India; Joy J.M., Biochemistry and Nutrition Division, ICAR-Central Institute of Fisheries Technology, Kerala, Cochin, 682029, India, Faculty of Marine Sciences, Cochin University of Science and Technology, Kerala, Cochin, 682022, India, St.Teresa's College (Autonomous), Kerala, Ernakulam, 682011, India; Mathew S., Biochemistry and Nutrition Division, ICAR-Central Institute of Fisheries Technology, Kerala, Cochin, 682029, India
Review on lightweight cryptography techniques and steganography techniques for IoT environment
Block cipher; Internet of things; Lightweight security solutions; Steganography
In the modern world, technology has connected to our day-to-day life in different forms. The Internet of Things (IoT) has become an innovative criterion for mass implementations and a part of daily life. However, this rapid growth leads the huge traffic and security problems. There are several challenges arise while deploying IoT. The most common challenges are privacy and security during data transmission. To address these issues, various lightweight cryptography and steganography techniques were introduced. These techniques help secure the data over the IoT. The hybrid of cryptography and steganography mechanisms provides enhanced security to confidential messages. Any messages can be secured by cryptography or by embedding the messages into any media files including text, audio, image, and video using steganography. Hence, this article has provided a detailed review of efficient, lightweight security solutions based on cryptography and steganography and their function over IoT applications. The objective of the paper is to study and analyze various Lightweight cryptography techniques and Steganography techniques for IoT. A few works of literature were reviewed in addition to their merits and limitations. Furthermore, the common problems in the reviewed techniques are explained in the discussion section with their parametric comparison. Finally, the future scope to improve IoT security solutions based on lightweight cryptography and steganography is mentioned in the conclusion part. The Author(s) under exclusive licence to The Society for Reliability Engineering, Quality and Operations Management (SREQOM), India and The Division of Operation and Maintenance, Lulea University of Technology, Sweden 2024.
International Journal of System Assurance Engineering and Management, Vol-15, No. 9, pp. 4210-4228.
Supriya K S., Christ University, Kengeri, India; Lovesum S. P J., Christ University, Kengeri, India
GrapheneLiquid Crystal Synergy: Advancing Sensor Technologies across Multiple Domains
This review explores the integration of graphene and liquid crystals to advance sensor technologies across multiple domains, with a focus on recent developments in thermal and infrared sensing, flexible actuators, chemical and biological detection, and environmental monitoring systems. The synergy between graphenes exceptional electrical, optical, and thermal properties and the dynamic behavior of liquid crystals leads to sensors with significantly enhanced sensitivity, selectivity, and versatility. Notable contributions of this review include highlighting key advancements such as graphene-doped liquid crystal IR detectors, shape-memory polymers for flexible actuators, and composite hydrogels for environmental pollutant detection. Additionally, this review addresses ongoing challenges in scalability and integration, providing insights into current research efforts aimed at overcoming these obstacles. The potential for multi-modal sensing, self-powered devices, and AI integration is discussed, suggesting a transformative impact of these composite sensors on various sectors, including health, environmental monitoring, and technology. This review demonstrates how the fusion of graphene and liquid crystals is pushing the boundaries of sensor technology, offering more sensitive, adaptable, and innovative solutions to global challenges. 2024 by the authors.
Adeshina M.A.; Ogunleye A.M.; Lee H.; Mareddi B.; Kim H.; Park J.
https://doi.org/10.3390/ma17174431 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85203624000&doi=10.3390%2fma17174431&partnerID=40&md5=127b8e1c4ac0b5593aec6b3526677016
Adeshina M.A., School of Electronic and Electrical Engineering, Kyungpook National University, Daegu, 41566, South Korea, Division of Biotechnology, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, 42988, South Korea; Ogunleye A.M., School of Electronic and Electrical Engineering, Kyungpook National University, Daegu, 41566, South Korea; Lee H., School of Electronic and Electrical Engineering, Kyungpook National University, Daegu, 41566, South Korea; Mareddi B., Electronics and Communication Engineering, Christ University, Bangalore, 560074, India; Kim H., Division of Biotechnology, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, 42988, South Korea; Park J., School of Electronic and Electrical Engineering, Kyungpook National University, Daegu, 41566, South Korea
Light as an elicitor for enhanced production of secondary metabolites in plant cell, tissue, and organ cultures
Cell culture; Cryptochromes; Elicitor; Fluorescent light; Light emitting diodes; Photoreceptors; Phytochromes; Ultraviolet light
Currently, in vitro cell, tissue, and organ cultures are used to produce plant secondary metabolites that are used as natural coloring agents, nutraceuticals, and medications. Various strategies have been applied for the hyperaccumulation of biomass and bioactive secondary compounds in vitro. The elicitation of cultured cells and organs with biotic and abiotic elicitors is an excellent strategy that has yielded promising results. Among various abiotic elicitors, light parameters such as light quality, intensity, and photoperiod have evolved as biotechnological tools to elicit cultures. Of the various light sources tested, ultraviolet (UV) lights, particularly UV-B, red, blue, and a mixture of light emitted by fluorescent light or light-emitting diodes, have yielded outstanding results and boosted the accumulation of bioactive compounds in cultured cells and organs. The objective of the current study was to evaluate light as an elicitor source and summarize the advantages and limitations of various light sources as elicitors for the bioaccumulation of secondary metabolites in vitro. The mechanism of the elicitation of secondary metabolism by UV and spectral light is discussed in this review. The Author(s), under exclusive licence to Springer Nature B.V. 2024.
Plant Growth Regulation, Vol-104, No. 1, pp. 31-49.
Murthy H.N., Department of Botany, Karnatak University, Dharwad, 580003, India, Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea, Department of Biotechnology, KLE Technological University, Hubballi, India; Joseph K.S., Department of Life Sciences, CHRIST (Deemed to be University), Bengaluru, 560029, India; Paek K.Y., Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea; Park S.Y., Department of Horticultural Science, Chungbuk National University, Cheongju, 28644, South Korea
Unraveling connections with artificial sweeteners and their impact on human health: A comprehensive review
artificial sweeteners; cancer; human health; neurological complications; synthetic food
There is a recent trend showing an uptick in the artificial sweetener's usage, particularly the nonnourishing variety. The allure of a low-calorie choice that lets people indulge in their sweet tooths while consuming less calories overall is what motivates this. Children's food products often contain a substantial number of artificial sweeteners due to their properties that aid in moisture retention, act as fillers, and serve as bulking agents. This article provides a comprehensive overview of artificial sweeteners and influences in human wealth. Studies have linked the use of artificial sweeteners to premature birth, highlighting the teratogenic potential of these compounds, particularly in beverages. Pregnant women who incorporate nonnutritive sweeteners into their diet during pregnancy are more likely to have children with birth defects, as indicated by studies on the subject. Artificial sweeteners should not be added to food for children because studies show that eating them while a child's body is still developing might disturb the balance of gut microbiota and cause potential problems like heart disease, stroke, and cognitive decline. The ingestion of nonnourishing sweeteners has adverse effects on the fertility of both men and women. Studies indicate that exceeding the recommended daily consumption that the FDA has set for artificial sweeteners can result in conditions of infertility for both genders. Additionally, there is a connection between the onset of cancer and the use of artificial sweeteners. Presently, a considerable amount of research relies on animal models rather than human ones, creating a notable gap in research. The limitation of extensive human model studies represents a drawback in validating results. Furthermore, there is a necessity for increased research focused on advancing techniques that can minimize the adverse effects of artificial sweeteners, making them more suitable for addressing issues related to obesity and various types of diabetes. 2024 The Author(s). eFood published by John Wiley & Sons Australia, Ltd. on behalf of International Association of Dietetic Nutrition and Safety.
Gopalakrishnan N.K.; Balasubramanian B.; Kundapur R.; Chaudhary A.; Meyyazhagnan A.; Pappuswamy M.
https://doi.org/10.1002/efd2.184 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85203202744&doi=10.1002%2fefd2.184&partnerID=40&md5=4c33aff55997dae5b4a3819e67077ced
Gopalakrishnan N.K., Department of Life Sciences, Christ University, Karnataka, Bangalore, India; Balasubramanian B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, South Korea; Kundapur R., Department of Life Sciences, Christ University, Karnataka, Bangalore, India; Chaudhary A., Department of Life Sciences, Christ University, Karnataka, Bangalore, India; Meyyazhagnan A., Department of Life Sciences, Christ University, Karnataka, Bangalore, India; Pappuswamy M., Department of Life Sciences, Christ University, Karnataka, Bangalore, India
Bioactive nanoparticles derived from marine brown seaweeds and their biological applications: a review
Bioactive compounds; Green synthesis; Metal nanoparticles; Reducing agent; Seaweeds
The biosynthesis of novel nanoparticles with varied morphologies, which has good implications for their biological capabilities, has attracted increasing attention in the field of nanotechnology. Bioactive compounds present in the extract of fungi, bacteria, plants and algae are responsible for nanoparticle synthesis. In comparison to other biological resources, brown seaweeds can also be useful to convert metal ions to metal nanoparticles because of the presence of richer bioactive chemicals. Carbohydrates, proteins, polysaccharides, vitamins, enzymes, pigments, and secondary metabolites in brown seaweeds act as natural reducing, capping, and stabilizing agents in the nanoparticles synthesis. There are around 2000 species of seaweed that dominate marine resources, but only a few have been reported for nanoparticle synthesis. The presence of bioactive chemicals in the biosynthesized metal nanoparticles confers biological activity. The biosynthesized metal and non-metal nanoparticles from brown seaweeds possess different biological activities because of their different physiochemical properties. Compared with terrestrial resources, marine resources are not much explored for nanoparticle synthesis. To confirm their morphology, characterization methods are used, such as absorption spectrophotometer, X-ray diffraction, Fourier transforms infrared spectroscopy, scanning electron microscope, and transmission electron microscopy. This review attempts to include the vital role of brown seaweed in the synthesis of metal and non-metal nanoparticles, as well as the method of synthesis and biological applications such as anticancer, antibacterial, antioxidant, anti-diabetic, and other functions. Graphical abstract: (Figure presented.). The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024.
Jaison J.P.; Balasubramanian B.; Gangwar J.; Pappuswamy M.; Meyyazhagan A.; Kamyab H.; Paari K.A.; Liu W.-C.; Taheri M.M.; Joseph K.S.
Bioprocess and Biosystems Engineering, Vol-47, No. 10, pp. 1605-1618.
ISSN: 16157591; PubMed ID: 38856773; CODEN: BBEIB
Jaison J.P., Department of Life Sciences, Christ University, Karnataka, Bangalore, 560 029, India; Balasubramanian B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, South Korea; Gangwar J., Department of Life Sciences, Christ University, Karnataka, Bangalore, 560 029, India; Pappuswamy M., Department of Life Sciences, Christ University, Karnataka, Bangalore, 560 029, India; Meyyazhagan A., Department of Life Sciences, Christ University, Karnataka, Bangalore, 560 029, India; Kamyab H., Department of Biomaterials, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, 600 077, India, Faculty of Architecture and Urbanism, UTE University, Calle Rumipamba S/N and Bourgeois, Quito, Ecuador; Paari K.A., Department of Life Sciences, Christ University, Karnataka, Bangalore, 560 029, India; Liu W.-C., Department of Animal Science, College of Coastal Agricultural Sciences, Guangdong Ocean University, P.R., Zhanjiang, 524088, China; Taheri M.M., Department of Pharmaceutical Biomaterials, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; Joseph K.S., Department of Life Sciences, Christ University, Karnataka, Bangalore, 560 029, India
Exploring the far-reaching consequences of malnutrition during pregnancy and beyond: A comprehensive review
Deficiency manifestations; Development; Fetal; Malnutrition; Microbiome; Supplementation
In India, maternal and infant malnutrition continues to be a significant contributor to health problems. Fetal malnutrition can result from an inadequate nutrient supply, necessary nutrition services, and ideal practices before, during, and following pregnancy. This comprehensive review delves into the complex relationships among hormone changes, microbial ecosystems, and nutrition, and how these relationships affect the health of mothers and their offspring. The review highlights how important it is to maintain good nutrition during pregnancy and to comprehend the dietary modifications that pregnant people make on their own to create interventions that work. Important minerals like calcium, iron, folic acid, iodine, and vitamin D are covered. Acknowledging the mutualistic association between the eating habits of mothers and the diverse microbiomes found in their gut, vagina, and oral channels, the review explores the influence on hormone levels and their consequences during gestation. Diverse fetal developmental needs are depicted by the table that outlines food requirements for each of the three trimesters. The detrimental effects of poor prenatal nutrition on a mothers health and its repercussions for neonates are examined. The effects of malnutrition after delivery, including difficulties throughout pregnancy, healing periods, and general effects on mental and physical health, are well studied. The study, which adopts a worldwide viewpoint, finds that societal norms, information gaps, and poverty are the main causes of malnutrition. Prevention techniques are discussed, emphasizing the significance of taking a comprehensive approach to addressing this vital issue in both the Indian and global contexts. 2024 Visagaa Publishing House.
Prabhakar L.; Herenjal S.S.; Deshpande M.K.; Choudhary A.; Chaudhary A.; Sana Ansar S.; Pappuswamy M.; Balasubramanian B.
Natural Resources for Human Health, Vol-4, No. 4, pp. 427-452.
All Open Access; Hybrid Gold Open Access
https://doi.org/10.53365/nrfhh/192940 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85205689509&doi=10.53365%2fnrfhh%2f192940&partnerID=40&md5=2a8dd173845ac82a4fd80149061d0453
Prabhakar L., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560 029, India; Herenjal S.S., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560 029, India; Deshpande M.K., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560 029, India; Choudhary A., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560 029, India; Chaudhary A., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560 029, India; Sana Ansar S., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560 029, India; Pappuswamy M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560 029, India; Balasubramanian B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, South Korea
Spiritual Intelligence and Spiritual Care in Nursing Practice: A Bibliometric Review
Bibliometric analysis; Bibliometric indicators; Healthcare; Nursing; Spiritual care; Spiritual intelligence; Spiritual quotient
Spiritual intelligence (SI) has recently gained traction in various fields, including nursing. Given the increasing emphasis on patient-centred care and the holistic well-being of patients and nurses, SI is particularly relevant in nursing practice. A bibliometric analysis of recent publications (20142024) in the field helps synthesise and evaluate the existing research on SI in the general field of nursing, identify literature gaps, suggest future research directions and raise awareness of the importance of SI in nursing practice. The present study reports bibliometric data (n = 461) from the Scopus database on SI, spiritual quotient and spiritual care in nursing and health care. The data are analysed using MS Excel and VOSviewer software. The publications trend analysis revealed a significant increase in SI-related publications since 2015. The study presents top-cited articles. Journal of Religion and Health was found to be a prominent journal with the maximum number of publications, and Sage was found to be the top publisher of journals with articles on SI. Network visualisation reveals central figures such as Wilfred McSherry, Trove Giske, Elizabeth Johnston Taylor, Fiona Timmins, Silvia Caldeira and Linda Ross as key researchers in the field. The United States and Iran have the most substantial connections of authors publishing on SI. This study reveals an increasing interest in SI and care within nursing research, confirming its growing significance in the field. By reporting areas where research on SI in nursing remains underdeveloped, the study paves the way for the development of new or updated curricula in nursing programs. The study can guide faculty development initiatives by highlighting the importance of SI and providing resources for educators to incorporate these concepts into their teaching. This study presents specific research questions to address these knowledge gaps. Future studies which can address these questions will enrich nursing education and practice, leading to improved patient outcomes and enhanced nurse well-being using the full potential of SI in nursing practice. 2024 Published by Scientific Scholar on behalf of Indian Journal of Palliative Care.
Indian Journal of Palliative Care, Vol-30, No. 4, pp. 304-314.
https://doi.org/10.25259/IJPC_155_2024 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85210966001&doi=10.25259%2fIJPC_155_2024&partnerID=40&md5=096c790ffc9efe266becb69491ef0d78
Stiliya J.K., Department of Psychology, Christ University, Karnataka, Bengaluru, India; Antony J.M., Department of Psychology, Christ University, Karnataka, Bengaluru, India; Joseph J., Department of Psychology, Christ University, Karnataka, Bengaluru, India
Amyotrophic Lateral Sclerosis: Insights and New Prospects in Disease Pathophysiology, Biomarkers and Therapies
amyotrophic lateral sclerosis; diagnosis; neuroinflammation; pathology; therapies
Amyotrophic Lateral Sclerosis (ALS) is a severe neurodegenerative disorder marked by the gradual loss of motor neurons, leading to significant disability and eventual death. Despite ongoing research, there are still limited treatment options, underscoring the need for a deeper understanding of the diseases complex mechanisms and the identification of new therapeutic targets. This review provides a thorough examination of ALS, covering its epidemiology, pathology, and clinical features. It investigates the key molecular mechanisms, such as protein aggregation, neuroinflammation, oxidative stress, and excitotoxicity that contribute to motor neuron degeneration. The role of biomarkers is highlighted for their importance in early diagnosis and disease monitoring. Additionally, the review explores emerging therapeutic approaches, including inhibitors of protein aggregation, neuroinflammation modulators, antioxidant therapies, gene therapy, and stem cell-based treatments. The advantages and challenges of these strategies are discussed, with an emphasis on the potential for precision medicine to tailor treatments to individual patient needs. Overall, this review aims to provide a comprehensive overview of the current state of ALS research and suggest future directions for developing effective therapies. 2024 by the authors.
Al-Khayri J.M.; Ravindran M.; Banadka A.; Vandana C.D.; Priya K.; Nagella P.; Kukkemane K.
https://doi.org/10.3390/ph17101391 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85207648670&doi=10.3390%2fph17101391&partnerID=40&md5=3cc971028850c6a78e095fc813a793bc
Al-Khayri J.M., Department of Agricultural Biotechnology, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa 31982, Saudi Arabia; Ravindran M., Department of Biotechnology and Genetics, School of Sciences, JAIN (Deemed-to-be-University), Bangalore, 560027, India; Banadka A., Department of Biotechnology and Genetics, School of Sciences, JAIN (Deemed-to-be-University), Bangalore, 560027, India; Vandana C.D., Department of Biotechnology and Genetics, School of Sciences, JAIN (Deemed-to-be-University), Bangalore, 560027, India; Priya K., Department of Biotechnology and Genetics, School of Sciences, JAIN (Deemed-to-be-University), Bangalore, 560027, India; Nagella P., Department of Life Sciences, School of Sciences, Christ University, Bengaluru, 560029, India; Kukkemane K., Department of Life Sciences, School of Sciences, Christ University, Bengaluru, 560029, India
Influencer Marketing and Consumer Behaviour: A Systematic Literature Review
Consumer Behaviour; Persuasion; Psychological Factors; Social Media Influencer; Social Networking Sites
Influencer marketing is an emerging area in the field of marketing. Specifically, this topic grabs the attention of several academicians and practitioners because of the key role played by influencers to stimulate consumer behaviour. Significantly, a systematic way of analysing and summarising the works of literature in this nascent area is necessary. A systematic literature review provides a comprehensive overview of the whole literature studied. From this knowledge, a systematic literature review has been undertaken from the period of 2016 to 2021 based on 65 articles from the ABDC journal to fetch relevant research themes, methodology, theories, variables, antecedents and consequences and potential research gaps. From this information, this research proposed an integrative framework which depicts the role of social media influencers in activating consumer behaviour. Future research direction has presented comprising of knowledge gap in the existing literature from key areas such as theory, methodology and settings. This research provides implications for both theories and practice. 2022 Management Development Institute.
Kanaveedu A., School of Business and Management, CHRIST (Deemed to be University), Karnataka, Bangalore, India; Kalapurackal J.J., School of Business and Management, CHRIST (Deemed to be University), Karnataka, Bangalore, India
Partition Refugees in Jammu Cry for Protection of Land and Job Rights
Article 370 was presented as an obstacle in the complete integration of Kashmir and it had denied citizenship and land rights to around 1.5 lakh West Pakistan Refugees (all Hindus) since their migration in 1947. However, after the lapse of merely five years of the abrogation, these WPRs, the new citizens of Jammu and Kashmir, have started feeling disillusioned and demanding protection of lands and jobs under Article 371 of the Indian Constitution. 2024 Economic and Political Weekly. All rights reserved.
Economic and Political Weekly, Vol-59, No. 42, pp. 18-21.
Slathia M., Christ (Deemed to be University), Bengaluru, India, The Department of International Studies, Political Science and History; Kumar A., Christ (Deemed to be University), Bengaluru, India, The Department of Media Studies
Will the antioxidant supplements impact the mitigation of oxidative stress in Parkinsons disease?
Antioxidants; Food supplements; Natural compounds; Neurodegenerative disorders; Oxidative stress
Parkinsons disease is a frequent neurodegenerative condition marked by both non-motor and motor symptoms. It is brought on by the selective depletion of dopamine neurons from the substantia nigra region of the midbrain. Numerous variables, including lifestyle, environment, age, smoking, and underlying medical disorders, affect the occurrence of Parkinsons disease. The free radicals created by oxidative stress have an impact on the morphology and function of neuronal cells and are a factor in many neurodegenerative disorders, including Parkinsons and Alzheimers, disorder. Although the pathophysiological mechanism causing neuronal degeneration is still unknown, oxidative stress plays a critical role in the pathogenesis of idiopathic Parkinsons disease. It also has an association with numerous proteins, including ?-synuclein, amyloid, DJ-1 protein and several signalling pathways like extracellular regulated protein kinases. Reactive oxygen species also contribute to complex Is mitochondrial respiratory activity. The naturally occurring antioxidants are the phenols, anthocyanins, carotenoids, flavonoids, vitamins, and lignans. These antioxidants retain the reactive oxygen species generation and plays a role in several biological effects. As a result, natural plant antioxidants may have an impact on Parkinsons disease and offer an alternative therapy that minimises oxidative stress and slows down the evolution of the disease. 2024 Visagaa Publishing House.
Anil Kumar D.; Balamuralikrishnan B.; Bharathi K.; Pushparaj K.; Pappuswamy M.; Meyyazhagan A.; Sangeetha T.; Kaviya M.; Vijaya Anand A.
Natural Resources for Human Health, Vol-4, No. 4, pp. 415-426.
https://doi.org/10.53365/nrfhh/192939 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85205707738&doi=10.53365%2fnrfhh%2f192939&partnerID=40&md5=1b74be25d6b72b33e61a924e07f4d329
Anil Kumar D., Medical Genetics and Epigenetics Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, Coimbatore, India; Balamuralikrishnan B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, South Korea; Bharathi K., Medical Genetics and Epigenetics Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, Coimbatore, India; Pushparaj K., Department of Zoology, School of Biosciences, Avinashilingam Institute for Home Science and Higher Education for Women, Tamil Nadu, Coimbatore, India; Pappuswamy M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560 029, India; Meyyazhagan A., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560 029, India; Sangeetha T., Medical Genetics and Epigenetics Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, Coimbatore, India; Kaviya M., Medical Genetics and Epigenetics Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, Coimbatore, India; Vijaya Anand A., Medical Genetics and Epigenetics Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, Coimbatore, India
Harnessing transition metal oxide?carbon heterostructures: Pioneering electrocatalysts for energy systems and other applications
Batteries; Composites; HER; OER; Supercapacitors; Transition metal oxides
Exponential demand for energy resources and fossil fuel substitution with green alternatives are essential to bringing sustainable development and a solution to the energy crisis. Transition metal oxides (TMOs) and their composites (TMOCs) as promising electrocatalysts to develop potential energy conversion and storage devices contribute to the solution to this crisis. The productivity of green fuels such as hydrogen from water-splitting reactions, the efficiency of energy storage and harvesting devices including supercapacitors and batteries, and the performance of electrochemical sensors can be remarkably enhanced with TMOs and their composites. Excellent electrochemical attributes, stability, abundant reserves, low cost, environment-friendly, and low toxicity make TMOs and their composites an excellent choice. The tunability of the physical and chemical properties of TMOs makes them attractive for research in designing different energy storage devices. This review presents a concise overview of the unique physical and electrochemical aspects of various TMOs and TMOCs, such as spinels, perovskites, and TMO-integrated carbon-based compounds, and their relevance for specific applications, emphasizing energy-related fields. The recent research advancements of TMOs-based functional materials for emerging applications, such as water splitting, fuel cells, supercapacitors, batteries, and sensing, are discussed. This review also highlights the advantageous properties and pertinent fabrication methods of TMOs and TMOCs for electrocatalysis, along with the methods to enhance their electrocatalytic abilities, which improve the overall efficiency of the desired applications. 2024
Merlin V S M.; Sariga; Jose S.; Varghese A.
Merlin V S M., Department of Chemistry, Christ University, Bengaluru, 560029, India; Sariga, Department of Chemistry, Christ University, Bengaluru, 560029, India; Jose S., Department of Chemistry, Christ University, Bengaluru, 560029, India; Varghese A., Department of Chemistry, Christ University, Bengaluru, 560029, India
Updated aspects of alpha-Solanine as a potential anticancer agent: Mechanistic insights and future directions
anticancer mechanisms; apoptosis; glycoalkaloids; Solanaceae; ?-Solanine
Cancer remains a critical global health challenge, with limited progress in reducing mortality despite advancements in diagnosis and treatment. The growing resistance of tumors to existing chemotherapy exacerbates this burden. In response, the search for new anticancer compounds from plants has intensified, given their historical success in yielding effective treatments. This review focuses on ?-solanine, a glycoalkaloid primarily derived from potato tubers and nightshade family plants, recognized for its diverse biological activities, including anti-allergic, antipyretic, anti-inflammatory, anti-diabetic, and antibiotic properties. Recently, ?-solanine has gained attention as a potential anticancer agent. Utilizing resources like PubMed/MedLine, ScienceDirect, Web of Science, Scopus, the American Chemical Society, Google Scholar, Springer Link, Wiley, and various commercial websites, this review consolidates two decades of research on ?-solanine's anticancer effects and mechanisms against nine different cancers, highlighting its role in modulating various signaling pathways. It also discusses ?-solanine's potential as a lead compound in cancer therapy. The abundant availability of potato peel, often discarded as waste or sold cheaply, is suggested as a sustainable source for large-scale ?-solanine extraction. The study concludes that ?-solanine holds promise as a standalone or adjunctive cancer treatment. However, further research is necessary to optimize this lead compound and mitigate its toxicity through various strategies. 2024 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC.
Nandi S.; Sikder R.; Nag A.; Khatua S.; Sen S.; Chakraborty N.; Naskar A.; Zhakipbekov K.; Acharya K.; Habtemariam S.; ArslanAte??ahin D.; Goloshvili T.; AhmedAldahish A.; Sharifi-Rad J.; Calina D.
Food Science and Nutrition, Vol-12, No. 10, pp. 7088-7107.
All Open Access; Green Open Access; Hybrid Gold Open Access
https://doi.org/10.1002/fsn3.4221 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85202883746&doi=10.1002%2ffsn3.4221&partnerID=40&md5=80d4618f510a22cd628ac2a5fc4f0aff
Nandi S., Molecular and Applied Mycology and Plant Pathology Laboratory, Department of Botany, University of Calcutta, Kolkata, India; Sikder R., Molecular and Applied Mycology and Plant Pathology Laboratory, Department of Botany, University of Calcutta, Kolkata, India; Nag A., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, India; Khatua S., Department of Botany, Faculty of Science, University of Allahabad, Uttar Pradesh, Prayagraj, India; Sen S., Department of Botany, Fakir Chand College, Kolkata, India; Chakraborty N., Department of Botany, Scottish Church College, Kolkata, India; Naskar A., Molecular and Applied Mycology and Plant Pathology Laboratory, Department of Botany, University of Calcutta, Kolkata, India; Zhakipbekov K., Department of Organization and Management and Economics of Pharmacy and Clinical Pharmacy, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan; Acharya K., Molecular and Applied Mycology and Plant Pathology Laboratory, Department of Botany, University of Calcutta, Kolkata, India; Habtemariam S., Pharmacognosy Research & Herbal Analysis Services UK, Kent, United Kingdom; ArslanAte??ahin D., Department of Plant and Animal Production, Baskil Vocational School, F?rat University, Elaz?g, Turkey; Goloshvili T., Department of Plant Physiology and Genetic Resources, Institute of Botany, Ilia State University, Tbilisi, Georgia; AhmedAldahish A., Department of Pharmacology, College of Pharmacy, King Khalid University, Abha, Saudi Arabia; Sharifi-Rad J., Department of Biomedical Sciences, College of Medicine, Korea University, Seoul, South Korea; Calina D., Department of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, Craiova, Romania
Heavy metal ion sensing strategies using fluorophores for environmental remediation
Analytical techniques; Biological fluorophores; Environmental issues; Heavy metal ions; Organic dyes; Quantum dots
The main aim of this review is to provide a holistic summary of the latest advances within the research area focusing on the detection of heavy metal ion pollution, particularly the sensing strategies. The review explores various heavy metal ion detection approaches, encompassing spectrometry, electrochemical methods, and optical techniques. Numerous initiatives have been undertaken in recent times in response to the increasing demand for fast, sensitive, and selective sensors. Notably, fluorescent sensors have acquired prominence owing to the numerous advantages such as good specificity, reversibility, and sensitivity. Further, this review also explores the advantages of various nanomaterials employed in sensing heavy metal ions. In this regard, exclusive emphasis is placed on fluorescent nanomaterials based on organic dyes, quantum dots, and fluorescent aptasensors for metal ion removal from aqueous systems, and to identify the fate of heavy metal ions in the natural environment. 2024
Shanmugavel A.; Rene E.R.; Balakrishnan S.P.; Krishnakumar N.; Jose S.P.
ISSN: 139351; PubMed ID: 38969312; CODEN: ENVRA
https://doi.org/10.1016/j.envres.2024.119544 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85200471128&doi=10.1016%2fj.envres.2024.119544&partnerID=40&md5=77478c78683400a0fb41579c4daf21d8
Shanmugavel A., School of Physics, Madurai Kamaraj University, Tamil Nadu, Madurai, 625021, India; Rene E.R., Department of Water Supply, Sanitation and Environmental Engineering, IHE Delft Institute for Water Education, Westvest 7, 2601DA, Delft, Netherlands; Balakrishnan S.P., Department of Chemistry, CHRIST (Deemed to Be University), Karnataka, Bengaluru, 560029, India; Krishnakumar N., School of Physics, Madurai Kamaraj University, Tamil Nadu, Madurai, 625021, India; Jose S.P., School of Physics, Madurai Kamaraj University, Tamil Nadu, Madurai, 625021, India