Evaluation of Photoswitching Properties for Hockey Stick-Shaped Mesogens Bearing Azo Benzene Moieties
azobenzene; hockey stick; optical storage devices; photoisomerization; thermal back relaxation
In this paper, we report the photoresponsive behavior of hockey stick-shaped mesogens bearing azo wing with different terminal alkoxy chains at one terminal end. Except for the compound E16, which exhibits SmC along with nematic phase, all other mentioned compounds exhibit nematic phase alone. Influence of chain length on the photophysical properties were investigated using UV-Vis spectroscopy. It is observed here that influence of chain length is negligible on thermal back relaxation time. Spectroscopic investigation with variable intensities of UV light studies reveals that reverse cis-trans isomerization process was inversely proportional to the intensity of illuminated light. The present study also reveals that the structure-property relationship plays a dominant role on shape anisotropic structures. A spectroscopic study of the solid sample using guest-host mixture was also carried out and the compilation of results forecast these mesogens as ideal candidates for optical storage devices. Copyright 2021 Sunil, Monika, Shanker, Hegde and Prasad.
Sunil B.N.; Monika M.; Shanker G.; Hegde G.; Prasad V.
https://doi.org/10.3389/fphy.2021.728632 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118639160&doi=10.3389%2ffphy.2021.728632&partnerID=40&md5=018023fede3f2e0ab1a850ff7fa0c566
Sunil B.N., BSN Centre for Nano-materials and Displays, B.M.S. College of Engineering, Bengaluru, India; Monika M., Centre for Nano and Soft Matter Sciences, Bengaluru, India; Shanker G., Department of Chemistry, Jnana Bharathi Campus, Bangalore University, Bengaluru, India; Hegde G., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India; Prasad V., Centre for Nano and Soft Matter Sciences, Bengaluru, India
Evaluation of physicochemical and biological properties of SnO2 and Fe doped SnO2 nanoparticles
Anticancer; Doping concentration; Green synthesis; Nanoparticles; Structural analysis
In recent decades, nanoparticle synthesis has been used for various physical and chemical methods. However, different toxic chemicals are used during this synthesis process to address these concerns, which has multiple effects on environmental toxicity and high cost. To avoid these problems, we need a cost-effective and environmentally friendly approach. In this study, green synthesis was used to make tin oxide (SnO2) and ferrous doped tin oxide (SFO) nanoparticles (NPs) from Morinda citrifolia leaf extracts. The X-ray diffraction patterns of SnO2 and SFO NPs reveal a tetragonal crystalline structure. From the FESEM image of synthesized SnO2 and SFO NPs, their spherical structure and chemical composition were identified by EDX spectrum. Through the DLS spectrum, the hydrodynamic size was observed at 66 and 61 nm for SnO2 and SFO NPs, respectively. In the FTIR spectrum, the OSnO stretching vibration peak arises at (606 & 509 cm?1 for SnO2 NPs) and (613 & 538 cm?1 for SFO NPs). Photoluminescence is used in materials to detect surface defects and impurity levels. The antibacterial activity of the SnO2, SFO NPs, and conventional antibiotics like amoxicillin NPs is effectively inhibited against S. aureus and E. coli bacterial strains. SFO NPs exhibit a higher antibacterial activity as compared to SnO2 and amoxicillin. The anticancer efficacy of increased SFO NPs compared to SnO2 NPs was tested against (MDA-MB-237) human breast cancer cells. These results suggest that Fe ions modified SnO2 NPs could be used in healthcare industrial applications to improve human health. 2022 Elsevier Ltd and Techna Group S.r.l.
Elamin N.Y.; Indumathi T.; Ranjith Kumar E.
Ceramics International, Vol-49, No. 2, pp. 2388-2393.
https://doi.org/10.1016/j.ceramint.2022.09.211 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85139025089&doi=10.1016%2fj.ceramint.2022.09.211&partnerID=40&md5=b2364d9c92201c5d935a29b12127d0b4
Elamin N.Y., Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11623, Saudi Arabia, Department of Chemistry, Sudan University of Science and Technology, Khartoum, Sudan; Indumathi T., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Ranjith Kumar E., Department of Physics, KPR Institute of Engineering and Technology, Tamil Nadu, Coimbatore, 641407, India
Evaluation of phytoconstituents of Triticum aestivum grass extracts on nutritional attributes, antioxidant, and antimicrobial activities against food pathogens with molecular in silico investigation
carbohydrates; diphenyl-1-picryl-hydrazyl; gas columnmass spectroscopy; proteins; Pseudomonas aeruginosa; Staphylococcus aureus
The plant-based medicine and diet is gaining importance in recent days. The consumption of Triticum aestivum grass in the form of juice and tablets is increasing among common people. The present study elaborates on the nutritional, antioxidant, and antimicrobial potential of a nongenetically modified type of T. aestivum grass, along with the evidence of molecular docking studies. The T. aestivum grass extracts like decoction, aqueous, ethanol, and chloroform were subjected to preliminary phytochemical tests, quantitative estimation, antioxidant analysis, and antimicrobial activity determination. The ethanolic extract that had good antioxidant and antimicrobial potential was subjected to gas columnmass spectroscopy (GCMS) analysis and the compounds identified were docked against the antioxidant and antimicrobial receptors. The decoction and aqueous extracts performed well in preliminary qualitative tests with the presence of most of the phytochemicals tested. The decoction, aqueous, and ethanolic extracts possessed good concentrations of the phytochemicals. The decoction had about 210.839.16 and 154.160.33mg/g of carbohydrates and proteins, respectively, while the aqueous extract had about 10.910.08mg/g of amino acids and the ethanolic extract had about 52.51.4mg/g of phenolic content, which were the highest concentration of the phytochemicals observed among the extracts. Along with phytochemical potential, good antioxidant potential in the DPPH and ABTS by decoction as well as ethanolic extract with nearly 40 and 90% inhibition, respectively, and in FRAP by aqueous extract with maximum OD value. The ethanolic extract exhibited the best inhibition potential against the Staphylococcus aureus about 281mm, Pseudomonas aeruginosa with 202mm, Bacillus cereus at 201mm by the ethanolic extract at 200?g concentration, and Aspergillus fumigatus and A. niger at 150mm by the aqueous extract at 200?g concentration. The GCMS analysis revealed the presence of terpenoids, alkaloids, and phenols, which on docking had highest binding capacity toward the antioxidant and antimicrobial receptors. 2023 The Authors. Food Frontiers published by John Wiley & Sons Australia, Ltd and Nanchang University, Northwest University, Jiangsu University, Zhejiang University, Fujian Agriculture and Forestry University.
Kaviya M.; Balamuralikrishnan B.; Sangeetha T.; Senthilkumar N.; Malaisamy A.; Sivasamy M.; Poorni L.; Pushparaj K.; Arun M.; Anand A.V.
Food Frontiers, Vol-4, No. 2, pp. 831-848.
https://doi.org/10.1002/fft2.233 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85157983994&doi=10.1002%2ffft2.233&partnerID=40&md5=2a68fedd40afeae4218bfbacb781054e
Kaviya M., Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, Coimbatore, India; Balamuralikrishnan B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, South Korea; Sangeetha T., Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, Coimbatore, India; Senthilkumar N., Department of Bioprospecting of Forest Resources, Institute of Forest Genetics and Tree Breeding (IFGTB), Forest Campus, Tamil Nadu, Coimbatore, India; Malaisamy A., Transcription Regulation Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India; Sivasamy M., Division of Crops Improvement, Indian Council of Agricultural Research (ICAR) - Indian Agricultural Research Institute, Regional Station, Wellington, Tamil Nadu, Nilgiris, India; Poorni L., Department of Biochemistry, Vivekanandha College of Arts and Sciences for Women, Tamil Nadu, Namakkal, India; Pushparaj K., Department of Zoology, School of Biosciences, Avinashilingam Institute for Home Science and Higher Education for Women, Tamil Nadu, Coimbatore, India; Arun M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Anand A.V., Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, Coimbatore, India
Evaluation of potential larvicidal and pupicidal activity of Cassia fistula L. synthesized silver nanoparticles against Aedes aegypti
Aedes aegypti; Cassia fistula; larvicidal; plant drugs; plant metabolites; pupicidal
Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHF) are fatal and are spread primarily by Aedes aegypti. Control measures against vector causing disease have still not been well documented. The fatality of these diseases has alarmed a need for the development of promising methods to control A. aegypti. Nanotechnology offers the utilization of nanosized particles to target specific disease causing vectors such as mosquitoes. In the present study, an attempt was designed to synthesize silver nanoparticles from Cassia fistula leaf extract and to test its efficacy in vector control. The synthesized silver nanoparticles were sized in the range of 59-62 nm. The silver nanoparticles were tested for their capability in larvicidal and pupicidal activity against all the larval stages and pupal stages of A. aegypti. The LC50 values demonstrated the lethal effect of the nano material against all the stages of A. aegypti. The study draws attention towards the usage of plant parts in nano product synthesis that can act as a potential insecticide. 2023, Indian journals. All rights reserved.
George J.A.; Rajendran R.; Anand A.; Paari K.A.
Medicinal Plants, Vol-15, No. 1, pp. 185-193.
George J.A., Department of Life Sciences, CHRIST University, Karnataka, Bangalore, 560029, India; Rajendran R., Department of Energy and Environmental Engineering, IICT, Hyderabad, 500007, India; Anand A., Department of Plant Science, Madurai Kamaraj University, Tamil Nadu, Madurai, 625021, India; Paari K.A., Department of Life Sciences, CHRIST University, Karnataka, Bangalore, 560029, India
Evaluation of Potential Toxicity of Calotropis gigantea Leaf Extract on Danio rerio: Bioactive Compounds, Oxidative Stress and Histological Toxicity Analysis
Calotropis gigantea; Histology; Oxidative Stress; Phytochemical Analysis; Zebrafish
A greater understanding of the ecotoxicological effects of plant-based products is required due to their increasing use. Despite its long-recognised medicinal properties, Calotropis gigantea possesses toxic characteristics that necessitate further investigation into its chemical composition and biological effects. This study evaluates the toxicity of crude C. gigantea leaf extracts on the freshwater fish Danio rerio over a 30-day exposure period. Alongside GCMS analysis, which identified 48 major constituents, the total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activity were assessed using the DPPH assay. The extracts exhibited a higher flavonoid content than phenolic content, indicating strong antioxidant potential. In contrast, biochemical analyses revealed that exposed fish showed significantly elevated levels of oxidative stress biomarkers, including succinate dehydrogenase (SDH), glutathione S-transferase (GST), glutathione reductase (GR), catalase (CAT), and superoxide dismutase (SOD), signifying cellular stress and disruption of redox homeostasis. Histological examinations of the liver, brain, muscle, and gills of treated fish demonstrated notable alterations. The gills exhibited lamellar fusion and epithelial lifting, impairing respiration. The brain showed neuronal vacuolation and degeneration, suggesting neurotoxicity, while muscle tissues displayed myofibrillar degeneration. Liver samples revealed hepatocyte necrosis and vacuolisation, indicative of metabolic dysfunction. Collectively, these enzymatic and systemic histopathological responses emphasise the toxicological impacts of C. gigantea extracts on aquatic organisms. The findings underscore the importance of ecotoxicological evaluations and the dual nature of medicinal plants such as C. gigantea, which can be both therapeutic and harmful. In addition to stressing the necessity for cautious application and further research to elucidate the mechanisms underlying their toxicity, this study provides valuable insights into the biological effects of plant-derived compounds. 2025, Dr Tarak Nath Podder Memorial Foundation. All rights reserved.
International Journal of Advancement in Life Sciences Research;Volume;8;Issue;4;pp.111-127
Dr Tarak Nath Podder Memorial Foundation
https://doi.org/10.31632/ijalsr.2025.v08i04.009 https://www.scopus.com/pages/publications/105023296898?origin=resultslist
Ganavi B.B., Department of Life Sciences, CHRIST University, Hosur Road, Bengaluru, 560029, India; Paari K.A., Department of Life Sciences, CHRIST University, Hosur Road, Bengaluru, 560029, India
Evaluation of relation of personality, parenting, stress and depression in patients with secondary amenorrhoea
Depression; Parenting style; Personality; Secondary amenorrhea; Stress
Background: Relatively few studies have assessed psychosocial correlates for secondary amenorrhea. Our study of the Gynaecological condition concerning personality factor (on introversion-extroversion dimension), parenting (authoritarian and authoritative) style, depression and perceived stress addresses this gap in the literature. The study inquires, whether these variables are related. Aims and objectives: To evaluate the relation of personality, parenting, stress and depression in patients with secondary amenorrhoea. Methods: Evaluation was done for forty-four young-adult female patients (with their fathers alive) affected by secondary amenorrhea, requesting help for menstrual disorders. The Parental Authority Questionnaire administered on the parent of patients, and Beck Depression Inventory, Perceived stress scale, Kundu Introversion-Extraversion Inventory on patients. In addition to that sixty healthy participants were recruited. The 104 participants were divided into two groups according to the presence (44 cases) or the absence (60 cases) of clinically diagnosed secondary amenorrhea. Results: Appropriate use of correlation coefficient followed by a test of significance revealed significant correlations between the variables which were hypothesised in accordance and hadbeen discussedregarding future research. Conclusions: Secondary amenorrhea was found to be possibly associated with personality factors, stress, depression and the kind of parenting individuals receive during their lifetime.
Andhra Pradesh Journal of Psychological Medicine, Vol-16, No. 2, pp. 138-145.
Reddy J.K., Department of Psychology, Christ University, Bangalore, Karnataka, India; Ghosh C.C., Department of Psychology, Christ University, Bangalore, Karnataka, India
Evaluation of Remote Sensing and Meteorological parameters for Yield Prediction of Sugarcane (Saccharum officinarum L.) Crop
Farming; MLR; NDVI; Prediction; Sugarcane; VCI; Yield
In the Agriculture sector, the farmers need a reliable estimation for pre-harvest crop yield prediction to decide their import-export policies. The present work aims to assess the impact of remote sensing-based derived products with Climate data on the accuracy of a prediction model for the sugarcane yield. The regression method was used to develop an empirical model based on VCI, Historical Sugarcane Yield, and Climatic Parameters of 75 districts of six major sugar-producing states of India. The MOD13Q1 product of MODIS on Board Terra Satellite at 16-day intervals was accessed during the growing season of sugarcane crop with 36 meteorological parameters for experimentation. The accuracy of the model was evaluated using R2, Root Mean square Metric (RMSE), Mean Absolute Error (MAE), and mean square error (MSE). The preliminary results concluded that the proposed methodology achieved the highest accuracy with (R2 =0.95, MAE=5.18, MSE=34.5, RMSE=5.87). The conclusion of the study highlighted that the coefficient of determination can be improved significantly by incorporating maximum and minimum temperature parameters with Remote sensing derived vegetation indices for the sugarcane yield. 2023 by the authors. Submitted for possible open access publication under the terms and conditions of the Creative Commons Attribution (CC BY NC) license (https://creativecommons.org/licenses/by-nc/4.0/).
Brazilian Archives of Biology and Technology, Vol-66
Saini P., NSUT East Campus (Formerly AIACTR), Guru Gobind Singh Indraprastha University, USICT, Delhi, India; Nagpal B., NSUT East Campus (Formerly AIACTR), Department of Computer Science and Engineering, Delhi, India; Garg P., Christ University, School of Sciences, Delhi, India; Kumar S., South Ural State University, Big Data & Machine Learning Lab, Chelyabinsk, Russian Federation
Evaluation of Social Media Marketing Literature in the Tourism Industry Using PRISMA
destination image; literature review; PRISMA; Social media marketing; tourism recovery
Social media is an effective communication and information-sharing tool for tourism enterprises and organisations. Tourism marketing shall tap the growing popularity of social media and internet users, embracing a technological shift by optimising the potential of social media. This research study evaluates the academic journal articles related to social media in the tourism industry published on EBSCOhost, ScienceDirect and Google Scholar academic databases from 2005 to 2022. The article adopts a content analysis approach to review the articles and to evaluate the present state of knowledge of social media marketing in academic literature. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) is used for reporting and screening the review papers. The articles were coded and categorised under six major themes: Marketing, Destination experience/image, Tourism recovery, Smart tourism, Communication and Promotion. The research analysis has identified two major areas: (a) Travellers/tourists Perspective which has a focus on their behavioural attitude and (b) Tourism Agencies Perspective which has a functional approach. Based on the review of the literature to give direction for further research, an improvised version of the definition for the term social media with the inclusion of more specific terms in it has been proposed with theoretical and practical implications. 2023 MICA-The School of Ideas.
Solanki M.S., Christ University, Karnataka, Bengaluru, India; Thomas J., Christ University, Karnataka, Bengaluru, India
Journal of Creative Communications;Volume;20;Issue;2;pp.263-279
Restricted Access; Hardcopy may be available in the library
https://doi.org/10.1177/09732586231202610 https://www.scopus.com/pages/publications/85176931662?origin=resultslist
Evaluation of tea (Camellia sinensis L.) phytochemicals as multi-disease modulators, a multidimensional in silico strategy with the combinations of network pharmacology, pharmacophore analysis, statistics and molecular docking
Diseases; Molecular docking; Network pharmacology; Phytochemicals; Simulation; Statistics; Tea
Tea (Camellia sinensis L.) is considered as to be one of the most consumed beverages globally and a reservoir of phytochemicals with immense health benefits. Despite numerous advantages, tea compounds lack a robust multi-disease target study. In this work, we presented a unique in silico approach consisting of molecular docking, multivariate statistics, pharmacophore analysis, and network pharmacology approaches. Eight tea phytochemicals were identified through literature mining, namely gallic acid, catechin, epigallocatechin gallate, epicatechin, epicatechin gallate (ECG), quercetin, kaempferol, and ellagic acid, based on their richness in tea leaves. Further, exploration of databases revealed 30target proteins related to the pharmacological properties of tea compounds and multiple associated diseases. Molecular docking experiment with eight tea compounds and all 30proteins revealed that except gallic acid all other seven phytochemicals had potential inhibitory activities against these targets. The docking experiment was validated by comparing the binding affinities (Kcalmol?1) of the compounds with known drug molecules for the respective proteins. Further, with the aid of the application of statistical tools (principal component analysis and clustering), we identified two major clusters of phytochemicals based on their chemical properties and docking scores (Kcalmol?1). Pharmacophore analysis of these clusters revealed the functional descriptors of phytochemicals, related to the ligandprotein docking interactions. Tripartite network was constructed based on the docking scores, and it consisted of seven tea phytochemicals (gallic acid was excluded) targeting five proteins and ten associated diseases. Epicatechin gallate (ECG)-hepatocyte growth factor receptor (PDB id 1FYR) complex was found to be highest in docking performance (10kcalmol?1). Finally, molecular dynamic simulation showed that ECG-1FYR could make a stable complex in the near-native physiological condition. Graphical abstract: [Figure not available: see fulltext.]. 2022, The Author(s), under exclusive licence to Springer Nature Switzerland AG.
Molecular Diversity, Vol-27, No. 1, pp. 487-509.
All Open Access; Bronze Open Access; Green Open Access
ISSN: 13811991; PubMed ID: 35536529; CODEN: MODIF
Nag A., Department of Life Sciences, Christ (Deemed to be University), Bangalore, India; Dhull N., Department of Life Sciences, Christ (Deemed to be University), Bangalore, India; Gupta A., Department of Life Sciences, Christ (Deemed to be University), Bangalore, India
Evaluation of test methods for fracture resistance of high modulus asphalt binders from rheological and mechanical perspectives
Fracture behavior; High modulus asphalt binder; Intermediate temperatures; Test method
High modulus asphalt binder (HMAB) has excellent rutting resistance but it might have premature cracking concerns due to its high stiffness. In this study, the intermediate temperature fracture performance of six HMABs was evaluated from a rheological and mechanical standpoint. The linear amplitude sweep (LAS) test, Glover-Rowe (G-R) parameter, and pure linear amplitude sweep (PLAS) test were employed for the rheological characterization, while the binder fracture energy (BFE) test and the double-edge notched tensile (DENT) test were implemented to investigate mechanical performance. The results show that HMABs have lower cracking resistance than conventional asphalt binders, and this was due to the insufficient ductility of their internal polymer networks. Of the five test methods, the PLAS, BFE, and DENT tests are highly recommended for evaluating the cracking resistance of HMABs at intermediate temperatures. 2022 Elsevier Ltd
Chen Y.; Zheng W.; Gao R.; Tebaldi G.; Hossiney N.
Construction and Building Materials, Vol-329
https://doi.org/10.1016/j.conbuildmat.2022.127216 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85126566675&doi=10.1016%2fj.conbuildmat.2022.127216&partnerID=40&md5=ecacfb113f24f0c67c22de48cfbee98d
Chen Y., School of Highway, Chang'an University, Middle Section of NanErhuan Road, Xi'an, 710064, China; Zheng W., School of Highway, Chang'an University, Middle Section of NanErhuan Road, Xi'an, 710064, China; Gao R., School of Highway, Chang'an University, Middle Section of NanErhuan Road, Xi'an, 710064, China; Tebaldi G., Department of Engineering and Architecture, University of Parma, Parma, I-43125, Italy; Hossiney N., Department of Civil Engineering, CHRIST University, Kumbalgodu, Karnataka, Bengaluru, 560074, India
EVALUATION OF THE ENVIRONMENTAL EFFECTS OF MEDICAL WASTE AND ITS INCREASE AFTER COVID-19 PANDEMIC
environmental impact; groundwater pollution; hazardous waste; heavy metals and mitigation strategies; improper disposal; medical waste; public health
Medical waste is a special course of harmful contaminants. Improper treatment would cause tributary environmental pollution, expressly when countering to communal health tragedies. However, there are quite few explores on the peer group of medical waste, and there is a deficiency of basic considerate of its spatial-temporal heterogeneity. The purpose of this study is to conduct a systematic estimation of the effectiveness of these incongruous discarding procedures in expressions of water eminence and wellbeing. The research is centred on municipal areas characterised by vital medical waste production, which has the probable to taint groundwater and water sources. A complex approach is exploited in the procedure, which comprises of water sample collection, laboratory analysis, field surveys, and GIS-based spatial mapping. Medical waste disposal hotspots, such as healthcare facilities, waste collection points, and disposal sites, will be acknowledged through field surveys. Inspects will be showed on water samples poised from a variability of sources, including lakes, rivers, and groundwater wells, to find pathogens, medical residues, heavy metals, and organic pollutants, which are all gauges of medical waste contamination. The test centre analysis will utilise chic policies to portion the deliberation of pollutants in water samples, thereby gauging the likely hazards they pose to marine ecosystems and human health. Longitudinal visualisation of uncleanness distribution through GIS-based mapping facilitates the credentials of vulnerable areas and potential pathways for pollutant transport. The findings of this research will offer significant helps to our understanding of the extent of environmental deterioration resulting from the inadequate disposal of medical refuse into urban water sources. The results of this study will provide valuable insights for the creation of alertness campaigns, regulatory frameworks, and mitigation strategies that are operative in talking this urgent environmental concern and shielding the truthfulness of water in municipal regions. 2024, Scibulcom Ltd.. All rights reserved.
Sharma B.; Sailaja M.; Bansal R.; Soujanya K.; Nerlekar T.; Acharjee P.B.; Rajagopal R.
Journal of Environmental Protection and Ecology, Vol-25, No. 6, pp. 1833-1845.
Sharma B., Geeta University, Panipat, India; Sailaja M., Department of CSE, Ravindra College of Engineering for Women, Kurnool, India; Bansal R., Department of Mittal School of Business, Lovely Professional University, Punjab, Phagwara, India; Soujanya K., Department of BBA, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Andhra Pradesh, Guntur, India; Nerlekar T., Department of Civil Engineering, Dr. D. Y. Patil Institute of Technology, Pimpri, Pune, India; Acharjee P.B., Department of Computer Science, CHRIST University, Bangalore, India; Rajagopal R., Department of Computer Science and Engineering, Alliance School of Advanced Computing, Alliance University, Karnataka, Bengaluru, India
Evaluation of the inhibition efficiency of Pogonatum microstomum for mild steel in acid medium using gravimetric, kinetics, electrochemical studies and statistical modeling
Electrochemical studies; Mild steel; Pogonatum microstomum; Statistical modelling
Mosses from a distinct lineage of bryophyte family are found as thick green carpet on the moist rocks, trees, soil or streams. It is acclaimed for its good antimicrobial properties and is a reservoir of various phytochemicals. The nontoxicity nature and abundant availability in nature was exploited for the first time to investigate its effectiveness as novel and green corrosion. Present study deals with the evaluation of corrosion inhibition efficiency of the moss, Pogonatum microstomum using the electrochemical studies and weight loss studies. The moss extract showed a maximum corrosion inhibition efficiency of 95.28 % for 3hrs of immersion period at 303 K. Increase in the inhibition efficiency with concentration of moss extract is the result of adsorption of the constituents which are active on the surface of the metal. Tafel polarization and electrochemical impedance studies gave results on par with the weight loss measurements. The experimental results obtained were further validated by statistical analysis and statistical modeling using SPSS 20 software. 2020 American Institute of Physics Inc.. All rights reserved.
Jomy J.; Hepziba Magie Jessima S.J.; Subhashini S.
https://doi.org/10.1063/5.0019455 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096428789&doi=10.1063%2f5.0019455&partnerID=40&md5=c7034e349bb337d13aa4f459f3800a6b
Jomy J., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560029, India; Hepziba Magie Jessima S.J., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560029, India; Subhashini S., Department of Chemistry, Avinashilingam Institute for Home Science and Higher Education for Women, Deemed to be University, Coimbatore, 641043, India
Evaluation of the Neuroprotective Efficacies and Related Mechanisms of Cirsimaritin in MPTP-Induced Parkinson in Mice with Following the Molecular Docking Studies
Apoptosis; Cirsimaritin; Dopamine; Neurodegeneration; Oxidative stress
Parkinsons disease (PD) is a progressive neurodegenerative disorder characterized by dopaminergic neuronal loss and oxidative stressinduced apoptosis. The present study evaluated the neuroprotective potential of cirsimaritin against MPTP-induced PD in mice and explored its possible mechanism through combined in silico and in vivo approaches. Molecular docking using AutoDock Vina revealed that cirsimaritin exhibits strong binding affinities with key antioxidant enzymes (CAT, GPx, and SOD) and apoptosis-related proteins (Bcl-2, Bax, caspase-3, ?8, and ? 9), suggesting possible modulation of oxidative and apoptotic signaling pathways. In vivo, PD was induced by MPTP (30mg/kg, i.p., for 7days), followed by oral administration of cirsimaritin (25 and 50mg/kg). Behavioral assessmentsincluding the open field, narrow beam walking, and wire hanging testsdemonstrated significant improvement in locomotor and neuromuscular performance in cirsimaritin-treated mice. Biochemical analyses revealed that cirsimaritin restored dopamine and its metabolites, decreased lipid peroxidation (TBARS), and enhanced antioxidant enzyme activities (CAT, SOD, and GPx). Additionally, cirsimaritin attenuated apoptosis by upregulating Bcl-2 and downregulating Bax and caspase-3 expression. Histopathological examination confirmed reduced neurodegeneration in the brain hippocampus of treated mice. These findings indicate that cirsimaritin exerts potent neuroprotective effects in MPTP-induced PD mice, likely through its antioxidant and anti-apoptotic actions, supporting its potential as a therapeutic candidate for Parkinsons disease. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2026.
Wei, Yan; Li, Qi; Hirad, Abdurahman Hajinur; Alarfaj, Abdullah A.; Thangavelu, Indumathi; Arulselvan, Palanisamy
Journal of Pharmaceutical Innovation;Volume;21;Issue;3;Article No.;244;
https://doi.org/10.1007/s12247-025-10345-5 https://www.scopus.com/pages/publications/105031736329?origin=resultslist
Wei Y., Department of Encephalopathy, Xian Hospital of Traditional Chinese Medicine, Xian, China; Li Q., Department of Encephalopathy, Xian Hospital of Traditional Chinese Medicine, Xian, China; Hirad A.H., Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box. 2455, 11451, Riyadh, Saudi Arabia; Alarfaj A.A., Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box. 2455, 11451, Riyadh, Saudi Arabia; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, India; Arulselvan P., Department of Biochemistry, Karpagam Academy of Higher Education (Deemed to be University), Tamilnadu, Coimbatore, 641021, India
Evaluation of therapeutic potentials of selected phytochemicals against Nipah virus, a multi-dimensional in silico study
Drug-likeliness; In silico; Molecular docking; Nipah virus; Phytochemicals; Simulation; Statistics
The current study attempted to evaluate the potential of fifty-three (53) natural compounds as Nipah virus attachment glycoprotein (NiV G) inhibitors through in silico molecular docking study. Pharmacophore alignment of the four(4) selected compounds (Naringin, Mulberrofuran B, Rutin and Quercetin 3-galactoside) through Principal Component Analysis (PCA) revealed that common pharmacophores, namely four H bond acceptors, one H bond donor and two aromatic groups were responsible for the residual interaction with the target protein. Out of these four compounds, Naringin was found to have the highest inhibitory potential ( 9.19kcalmol?1) against the target protein NiV G, when compared to the control drug, Ribavirin ( 6.95kcalmol?1). The molecular dynamic simulation revealed that Naringin could make a stable complex with the target protein in the near-native physiological condition. Finally, MM-PBSA (Molecular Mechanics-PoissonBoltzmann Solvent-Accessible Surface Area) analysis in agreement with our molecular docking result, showed that Naringin ( 218.664kJmol?1) could strongly bind with the target protein NiV G than the control drug Ribavirin ( 83.812kJmol?1). 2023, King Abdulaziz City for Science and Technology.
Springer Science and Business Media Deutschland GmbH
https://doi.org/10.1007/s13205-023-03595-y https://www.scopus.com/inward/record.uri?eid=2-s2.0-85159038122&doi=10.1007%2fs13205-023-03595-y&partnerID=40&md5=7f91fbceb04e03a679cd2f4e1acd86c0
Rababi D., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore Central Campus, Bangalore, India; Nag A., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore Central Campus, Bangalore, India
Evaluation of tourism infrastructure around the ancient marvels of Mahabalipuram and Pattadakal
India is rich in culture and well-known for its mythological knowledge. It has plenty of architectural marvels recognized by UNESCO and maintained by the Archaeological Survey of India (ASI). For this chapter, two of the cultural UNESCO sites, Mahabalipuram and Pattadakal, have been taken as the scope of the chapter. The introduction section talks about the history of the monuments and provides a brief overview of the tourism infrastructure. The following section, evaluation of tourism infrastructure, aims to analyze Mahabalipuram and Pattadakal's tourism infrastructure using four parameters: transportation and connectivity, accommodation, gastronomical facilities, and tourist amenities. An observational study of the sites was conducted between December 2023 and January 2024. This is followed by the recommendations provided by the authors to improve the tourism infrastructure in these sites and, finally, the chapter's conclusion and future scope for researchers. 2024, IGI Global. All rights reserved.
Building Community Resiliency and Sustainability With Tourism Development, pp. 148-170.
Kumar S.S., Christ University, India; John S., Christ University, India
Evaluation of Virtual Reality Experiential Dimensions using Sentiment Analysis
Customer Satisfaction; Illusion; Immersion; Virtual Reality
Experiential technologies like Virtual Reality (VR) are revitalizing the gaming industries through higher immersive and interactive gaming experiences. The immersive technology has a considerable impact on the industry and will evolve simultaneously as the technology continues to update and improve further. Indian tech cities Bangalore, Delhi NCR, Mumbai, Kolkata, Chennai, Pune, and Hyderabad were chosen for the study and the user-generated content was scraped from the top gaming centers of each city. User Generated Content analysis is gaining immense interest among businesses for devising better decision-making and marketing strategies. The study devised an integrated framework comprised of web data scraping, data cleaning, data pre-processing, AI model designing, sentiment analysis, logistic regression model, and support vector machine model. Logistic Regression predicted the sentiment of the text and the Support Vector Machine classified the VR experiential dimensions and helped in understanding the most important dimension for customer satisfaction. The study has found that VR experiences are gaining positive responses among the customers and illusion emerges as the most significant dimension for their satisfaction. 2024 IEEE.
Proceedings of the 2nd International Conference on Intelligent and Innovative Technologies in Computing, Electrical and Electronics, ICIITCEE 2024
Institute of Electrical and Electronics Engineers Inc.
Rina Daline T., Christ University, Bengaluru, India; Thomas J., Christ University, Bengaluru, India
Evaluation of web applications based on UX parameters
HCI; Responsive web; User experience; UX parameters; Web 2.0
The objective of evaluating User Experience (UX) in this era of technology is to enhance the user satisfaction. Earlier applications were built with the aim of reducing the work of users. But with the evolution of the technology, the emergence of new gadgets and new trends in the information technology, the applications had to be more user-centric. The primary objective of this research is to evaluate the user experience of web applications based on different UX parameters using different techniques and given a rating. Each of these ratings are combined to determine the overall rating of UX for the web application. Also, the secondary objective of this research is to provide suggestions or recommendations based on the ratings to improve the UX of the web applications. An experimental study was conducted and the results show a significant improvement. Areas of further enhancements have also been identified and presented. 2019 Institute of Advanced Engineering and Science.
International Journal of Electrical and Computer Engineering, Vol-9, No. 4, pp. 2564-2570.
Institute of Advanced Engineering and Science
All Open Access; Gold Open Access; Green Open Access
https://doi.org/10.11591/ijece.v9i4.pp2564-2570 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85066243393&doi=10.11591%2fijece.v9i4.pp2564-2570&partnerID=40&md5=19a1dd7f3d2fc18593adf429e62bcd7d
Mistry A., Department of Computer Science, CHRIST (Deemed to Be University), Bengaluru, Karnataka, 560 029, India; Rajan R.A.P., Department of Computer Science, CHRIST (Deemed to Be University), Bengaluru, Karnataka, 560 029, India
Evaluation of Wound Healing Effect of Curcumin Loaded OPL Carbon Nanospheres Embedded Chitosan Membranes
Carbon nanospheres; Chitosan; Curcumin; MRSA infection; Wound healing
Biowaste-derived carbon biomaterial scaffolds are being used for wound healing and are the focus of interest. Carbon nanospheres derived from oil palm leaves without any catalysts via pyrolysis were loaded with a traditional drug curcumin. The wound healing scaffolds were fabricated on the PP non-woven fabric support using chitosan as the biopolymer matrix. Prepared carbon nanospheres and the scaffolds were characterized using ATR-IR and FESEM techniques. The wettability of scaffolds was examined to ensure the feasible moisture absorption ability, in vitro drug release profile and in vitro antibacterial activity against two strains of bacteria. The in vivo wound healing feature of scaffolds was studied by excision wound model for MRSA infected wound. Measured wound contraction percentage and the bacterial count on wounds at regular time intervals proved that, the scaffold dressed with chitosan and curcumin loaded carbon nanospheres showed an efficient reconstruction of skin through histopathological investigations. 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
M R.; S J.M.; Velmurugan R.; Hegde G.; Soontarapa K.; Keri R.S.
Journal of Polymers and the Environment, Vol-30, No. 12, pp. 5190-5201.
M R., Centre for Nano and Material Sciences, Jain University, Jain Global Campus, Kanakapura, Ramanagaram, Bangaluru, 562112, India; S J.M., Department of Chemistry, AMC Engineering College, Bannerughatta Main Road, Bengaluru, 560083, India; Velmurugan R., Department of Biochemistry, Chulalongkorn University Bangkok, Bangkok, 10330, Thailand; Hegde G., Center for Advanced Research and Development (CARD), CHRIST (Deemed to be University), Bangalore, 560029, India, Department of Chemistry, CHRIST (Deemed to be University), Bangalore, 560029, India; Soontarapa K., Department of Chemical Technology, Faculty of Sciences, Center of Excellence on Petrochemical and Materials Technology, Chulalongkorn University, Phayathai Road, Bangkok, 10330, Thailand; Keri R.S., Centre for Nano and Material Sciences, Jain University, Jain Global Campus, Kanakapura, Ramanagaram, Bangaluru, 562112, India, Organic and Medicinal Chemistry Laboratory, Centre for Nano and Material Sciences, Jain University, Jain Global Campus, Jakkasandra Post Kanakapura Road Ramanagara District, Karnataka, Bengaluru, 562112, India
Evaluation on effect of alkaline activator on compaction properties of red mud stabilised by ground granulated blast slag
Alkaline activator; Assessing compaction energy; Evaluating compaction properties; Ground granulated blast slag; Red mud
Any industrial waste has a potential to be used as a civil engineering material with an effective and appropriate waste management system. Like many industrial wastes, red mud (RM) and Ground granulated blast slag (GGBS) are some of the industrial wastes produced from aluminium and steel industries respectively. Utilization of only waste materials will not be effective without a suitable stabilizer, which forced to use an alkaline activator to satisfy the needs of a building materials. This paper evaluates measurements to assess the effect of alkaline activator on the compaction properties of GGBS stabilized RM. Different ratios of NaOH to Na2SiO3 was used as an alkaline activator with 10, 20 and 30 percentage replacement of GGBS to RM and measured the compaction properties by using a mini compaction apparatus. Upon conducting standard and modified proctor compaction tests for various combinations of RM and GGBS, the compaction curves depicted that huge variation in maximum dry density and optimum moisture content with the change of GGBS percentage and different ratios of NaOH to Na2SiO3 are measured and analysed. Further the influence of compaction energy on the density characteristics of these trails were assessed for better understanding. Copyright: This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
International Measurement Confederation (IMEKO)
https://doi.org/10.21014/acta_imeko.v11i1.1200 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85128212957&doi=10.21014%2facta_imeko.v11i1.1200&partnerID=40&md5=33882a8894153a5664336afa403fd8ba
Chandra S., Department of Civil Engineering, Jawaharlal Nehru Technological University Anantapur, Anantapur, India, Department of Civil Engineering, Christ (Deemed to be University), Karnataka, Bangalore, 560029, India; Krishnaiah S., Department of Civil Engineering, Jawaharlal Nehru Technological University Anantapur, Andhra Pradesh, Anantapur, 515002, India