Engineered biocorona on microplastics as a toxicity mitigation strategy in marine environment: Experiments with a marine crustacean Artemia salina
subject: Algae; Brine shrimp; Cell free extract; Engineered biocorona; Microplastics; Toxicity mitigation
description: The marine environment has become a major sink for microplastics (MPs) wastes. When MPs interact with biological macromolecules, the biocorona forms on their surface, which can alter their biological reactivity and toxicity. In this study, we investigated the impact of biocorona formation on the toxicity of aminated (NH2) and carboxylated (COOH) polystyrene MPs towards the marine crustacean Artemia salina. Biocoronated MPs were prepared using cell-free extracts (CFEs) from microalgae Chlorella sp. (phytoplankton) and the brine shrimp Artemia salina (zooplankton). The results revealed that biocorona formation effectively reduced the toxicity of MPs. Pristine NH2-MPs exhibited higher reactive oxygen species production (ROS) (182%) compared to COOH-MPs (162%) in Artemia salina. Notably, NH2-MPs coronated with brine shrimp CFE exhibited a substantial reduction in ROS production (127%) than those coronated with algal CFE, with COOH-MPs showing a similar trend (120%). Biocorona formation also significantly decreased malondialdehyde (MDA) levels and antioxidant activity compared to pristine MPs. Molecular docking and dynamics simulations demonstrated a strong binding between polystyrene and acetylcholinesterase (AChE). In vitro studies indicated that pristine NH2-MPs exhibited more reduction in AChE activity (84%) compared to COOH-MPs (95%). However, no significant reduction in AChE activity was observed upon exposure to MPs coronated with either algal or brine shrimp cell-free extracts. Independent action modeling indicated an antagonistic interaction for MPs coronated with both the CFEs. Pearson correlation and cluster heatmap analysis suggested that the toxicity reduction in Artemia salina might be driven by decreased oxidative stress followed by the corona formation. Overall, this study provides valuable insights into the potential of biomolecules from phytoplankton and zooplankton to reduce MPs toxicity in Artemia salina, while highlighting their role in modulating th…
creator: Rex M C.; Bairoliya A.; Gairola S.; Sureshkumar P.; Niranjan V.; Nag A.; Mukherjee A.
source: Journal of Hazardous Materials Advances, Vol-17
publisher: Elsevier B.V.
date: 2025-01-01
rights: All Open Access; Gold Open Access
relation: ISSN: 27724166
format: Online
language: English
type: Article
coverage: Rex M C., Centre for Nanobiotechnology, VIT, Tamil Nadu, Vellore, 632014, India; Bairoliya A., Centre for Nanobiotechnology, VIT, Tamil Nadu, Vellore, 632014, India; Gairola S., Centre for Nanobiotechnology, VIT, Tamil Nadu, Vellore, 632014, India; Sureshkumar P., R V College of Engineering, Karnataka, Bengaluru, India; Niranjan V., R V College of Engineering, Karnataka, Bengaluru, India; Nag A., Department of Life Sciences, Christ University, Karnataka, Bengaluru, India; Mukherjee A., Centre for Nanobiotechnology, VIT, Tamil Nadu, Vellore, 632014, India

Designing a One-Pot Ternary Fe-Mn-Zn Oxide Positive Electrode with Enhanced Energy-Storage Properties for Hybrid Supercapacitors
description: In recent years, ternary metal-oxide nanocomposite-based active electrodes have been investigated more effectively for supercapacitor applications due to the existence of a greater number of electroactive sites and the synergistic effect of three different transition-metal ions. Herein, Fe-Mn-Zn oxide ternary nanocomposites are synthesized using a simple and cost-effective one-pot hydrothermal approach. The characterizations of XRD, FTIR, FESEM, EDX, HRTEM, and XPS are analyzed for the synthesized Fe-Mn-Zn oxide nanocomposites to study their phases, functional groups, morphologies, purity, and binding energies. The electrochemical characteristics for the developed electrodes are studied in a three-electrode technique using CV, GCD, EIS, and a cyclic stability test. As expected, the ternary nanocomposite electrode of Fe-Mn-Zn oxide reveals a maximum specific capacitance (Cspc1) of 1673.4 F/g in comparison to other developed electrodes of ZnFe2O4 (271.7 F/g) and ZnMn2O4 (412.7 F/g) at the appropriate scan rate of 10 mV/s. In addition, the Fe-Mn-Zn oxide ternary nanocomposite active electrode exhibits 2616.25 F/g of total capacitance (qT**), 686.94 F/g of outer capacitance (qO**), and 1929.30 F/g of inner capacitance (qI**) which are determined by Trasatti analysis. Moreover, the fabricated hybrid supercapacitor device provides a good specific capacitance of 320.8 F/g, a high energy density of 75.3 Wh/kg at the power density of 649.9 W/kg at 1 A/g of current density range, and 88.75% of superior capacitive retention over 10,000 cycles at 10 A/g. Therefore, a ternary metal-oxide nanocomposite electrode is proposed to be a promising material for energy-storage devices. 2024 American Chemical Society.
creator: Subramaniyan S.; Veerasingam M.; Feroz Gandhi K.; Arumugam V.; Muthusamy K.K.; Sakkarapani S.
source: Energy and Fuels, Vol-39, No. 1, pp. 906-920.
publisher: American Chemical Society
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 8870624; CODEN: ENFUE
format: Online
language: English
type: Article
coverage: Subramaniyan S., Department of Physics, Alagappa University, Tamil Nadu, Karaikudi, 630003, India; Veerasingam M., Department of Chemistry, Mount Zion College of Engineering and Technology, Thirumayam, Pudukkottai, 622 507, India; Feroz Gandhi K., Department of Physics, Alagappa University, Tamil Nadu, Karaikudi, 630003, India; Arumugam V., Department of Physics, Panimalar Engineering College, Tamilnadu, Chennai, 600 123, India; Muthusamy K.K., Department of Physics and Electronics, CHRIST (Deemed to be University), Bengaluru, 560 029, India; Sakkarapani S., Department of Physics, Alagappa University, Tamil Nadu, Karaikudi, 630003, India

Unveiling the realm of AI governance in outer space and its importance in national space policy
subject: Artificial intelligence; Machine learning; Outer space; Regulation; Space objects
description: This article explores the notable legal concerns that may arise from the growing utilisation of artificial intelligence and machine learning in outer space. Whether it is conducting space exploration, clearing orbital debris, or extracting resources from specific areas in space, these activities are becoming more popular. Therefore, it is necessary to establish a regulatory framework to ensure consistency and objective standards. In order for national space legislation to effectively address the challenges presented by activities involving robots with different levels of autonomy and numerous objectives, it is essential to appraise the nature of these challenges. The article aims to investigate the relationship between the Montreal Declaration for a Responsible Development of Artificial Intelligence, 2017, and outer space laws and principles. It also examines the legal status of autonomous space objects, such as planetary rovers that are currently in operation or will be in the near future. Ultimately, the article highlights the importance of national space policy in addressing the appropriate regulation of artificial intelligence in outer space. In conclusion, this article has also discussed the potential effectiveness of utilising artificial intelligence-based methodologies and strategies to enhance current space policy. 2024 IAA
creator: Dey A.; Jagadanandan J.
source: Acta Astronautica, Vol-228, pp. 253-264.
publisher: Elsevier Ltd
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 945765; CODEN: AASTC
format: Online
language: English
type: Article
coverage: Dey A., School of Law, Christ University, Bangalore Campus, Karnataka, 560 029, India; Jagadanandan J., School of Law, Christ University, Bangalore Campus, Karnataka, 560 029, India

A strong technique for solving the fractional model of multi-dimensional Schnakenberg reaction-diffusion system
subject: fractional derivative; Laplace transform; Mathematical modeling; PDE with biochemisty; Power series method
description: In recent times, researchers have increasingly directed their focus toward Reaction-Diffusion models, attracted by their versatile applications across various scientific domains. Within these models, the Schnakenberg Reaction-Diffusion System (SRDS) has gained significant attention for its ability to explain intricate phenomena such as oscillatory behavior, limit cycles, pattern formations and diffusion in biochemistry. This paper specifically delves into the Fractional Schnakenberg Reaction Diffusion System (FSRDS), an extension of SRDS that incorporates principles of fractional calculus. This extension provides a more comprehensive framework for understanding complex dynamics. The unique aspect of this work lies in the innovative approach used to derive an analytical solution for FSRDS - the Residual Power Series Method with Laplace Transform (L.T.)/Laplace Residual Power series Method (LRPSM). By employing LRPSM and considering the provided initial conditions, our objective is to unveil an analytical solution for FSRDS. 2025 World Scientific Publishing Company.
creator: Jagatheeshwari R.; Ravichandran C.; Veeresha P.; Nisar K.S.
source: Modern Physics Letters B
publisher: World Scientific
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 2179849; CODEN: MPLBE
format: Online
language: English
type: Article
coverage: Jagatheeshwari R., Department of Mathematics, Kumaraguru College of Liberal Arts and Science, Tamil Nadu , Coimbatore, 641049, India; Ravichandran C., Department of Mathematics, Kongunadu Arts and Science College, Tamil Nadu , Coimbatore, 641029, India; Veeresha P., Department of Mathematics, CHRIST (Deemed to be University), Bengaluru, 560029, India; Nisar K.S., Department of Mathematics, College of Science and Humanities in Alkharj, Prince Sattam Bin Abdulaziz University, Alkharj, 11942, Saudi Arabia

Optical properties of MnTe2 few-layer quantum dots
subject: DFT; MnTe2; Photoluminescence; QDs
description: Quantum dots (QDs) are gaining attention as a possible emissive material that might be used in flexible optoelectronic and photonic systems. In the present work, the temperature-dependent photoluminescence (TDPL) property of manganese di-telluride (MnTe2) QDs was investigated. The room-temperature PL is attributed to the abrupt breakage of the large-area MnTe2 nanosheets by ultrasonication, which integrates defect-mediated localized trap states inside the electronic bandgap. As a result, deliberately generated defect states ultimately generate such PL emission of QDs. Density functional theory (DFT) results further validate the experimental interpretations of the origin of TDPL. In addition, through an in-situ liquid diffusion approach, the QDs were also integrated into a NaCl matrix. Due to light scattering properties, the hybrid crystals exhibit fluorescence centres at various excitation wavelengths. These results suggest that these MnTe2 QDs can be used as an effective basis for future flexible optoelectronic applications. 2024 Elsevier B.V.
creator: Ninan G.G.; Varghese M.; Gowda C.C.; Bylappa Y.; Nag A.; Balachandran M.; Junior L.R.; Tromer R.; Galvao D.S.; Tiwary C.S.; Kumbhakar P.
source: Optical Materials, Vol-159
publisher: Elsevier B.V.
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 9253467; CODEN: OMATE
format: Online
language: English
type: Article
coverage: Ninan G.G., Department of Physical Sciences and Mathematics, St. Francis de Sales College (Autonomous), Electronics City, Karnataka, Bengaluru, 560100, India, Department of Physics and Electronics, CHRIST (Deemed to be University), Bangalore, 560029, India; Varghese M., Department of Physics and Electronics, CHRIST (Deemed to be University), Bangalore, 560029, India; Gowda C.C., School of Nano Science and Technology, Indian Institute of Technology, West Bengal, Kharagpur, 721302, India; Bylappa Y., Department of Life Science, CHRIST (Deemed to be University), Bangalore, 560029, India; Nag A., Department of Life Science, CHRIST (Deemed to be University), Bangalore, 560029, India; Balachandran M., Department of Physics and Electronics, CHRIST (Deemed to be University), Bangalore, 560029, India; Junior L.R., Institute of Physics, University of Brasilia, DF, Brasilia, 70910-970, Brazil; Tromer R., Applied Physics Department, State University of Campinas, SP, Campinas, 13083-970, Brazil; Galvao D.S., Applied Physics Department, State University of Campinas, SP, Campinas, 13083-970, Brazil; Tiwary C.S., School of Nano Science and Technology, Indian Institute of Technology, West Bengal, Kharagpur, 721302, India, Metallurgical and Materials Engineering, Indian Institute of Technology Kharagpur, Kharagpur, 721302, India; Kumbhakar P., Department of Physics and Electronics, CHRIST (Deemed to be University), Bangalore, 560029, India, Metallurgical and Materials Engineering, Indian Institute of Technology Kharagpur, Kharagpur, 721302, India

Redefining copreneurs: a four decadal review adopting computer aided text analysis
subject: Copreneurs; Copreneurship; Definition; Family business; Structured review; Text-analysis
description: The study defines copreneurs and presents a four decadal review on copreneurial literature. The purpose is to bring conceptualization and characterization of copreneurs, on surface from its fragmented literature. A structured literature review on copreneurship research published between 1984 and 2023 is conducted. The search is made adopting indexing (Scopus, Clarivate and ABDC), digital libraries including ProQuest and EBSCO, and research articles published in journals by renowned publishers namely Elsevier, Emerald, Inderscience, Sage, Springer, Taylor & Francis and Wiley. Inclusion/exclusion criteria was defined and duplicates were eliminated. Finally, using POWER review model, the existing literature is organized under six themes namely Gender Roles, Spousal Support & Relationship Satisfaction, Work Life Balance, Business Commitment & Motivation, Leadership & Decision Making and Division of Labour & Responsibilities in the Intertwined Worlds. Using Inter- Rater Reliability, five definitions of copreneurs were framed and rated by nine experts from academics and industry. Finally, the definition with highest score and acceptable I-CVI value for simplicity & clarity is proposed. The fragmented literature on copreneurs speaks volume about the need for more impactful research on them. By using the proposed definition of copreneurs, scholars can uniformly identify the copreneurs, with future opportunities for micro-level research on copreneurs. Policy makers can utilise the findings of these research and formulate schemes, policies & programmes for betterment of copreneurs. The study intends to bridge the disciplinary gaps existing for identifying copreneurs and serve as a foundation for information sharing, regarding copreneurs and their entrepreneurial practices. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.
creator: Mahanti K.; Bhatia N.; Rana S.
source: International Entrepreneurship and Management Journal, Vol-21, No. 1
publisher: Springer
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 15547191
format: Online
language: English
type: Article
coverage: Mahanti K., Department of Business Administration, School of Management Sciences, Central University of Jharkhand, Jharkhand, Ranchi, India, School of Business and Management, CHRIST University, Karnataka, Bengaluru, India; Bhatia N., Department of Business Administration, School of Management Sciences, Central University of Jharkhand, Jharkhand, Ranchi, India; Rana S., College of Healthcare Management and Economics, Gulf Medical University, Ajman, United Arab Emirates

Comprehensive spectro-temporal studies of GX 17+2 using AstroSat observations
subject: Accretion, accretion discs; Stars: neutron; X-rays: binaries: GX 17+2
description: We performed a comprehensive spectro-temporal study of the Z-type neutron star low-mass X-ray binary GX 17+2 using long term data from the AstroSat/Soft X-ray Telescope (SXT) and Large Area X-ray Proportional Counter (LAXPC). The hardnessintensity diagrams (HIDs) of the source revealed a positive correlation between the hardness and intensity, characteristic of soft spectral state. Additionally, the LAXPC-20 HID showed the presence of secular shifts in both hardness and intensity. Time-averaged spectral modelling in the 0.7 ? 30.0 keV energy range indicated that the spectra could be well fitted with the model combination: constant edge edge tbabs thcomp bbodyrad. This analysis yielded a blackbody radius (Rbb) of ?59 km, photon index (?) of ?2.84 and electron temperature (kTe) of ?4.84 keV. Time-averaged temporal analysis revealed normal branch oscillations (NBOs) at ? 7 Hz in Observations 1 and 3, flaring branch oscillation (FBO) at ?15 Hz in Observation 2, and horizontal branch oscillation (HBO) at ?36 Hz in Observation 5. Flux resolved spectro-temporal analysis indicated that the source remained in the soft spectral state throughout all observations. A positive correlation was observed between kTbb, Fbb and Fbol, whereas an anti-correlation was noted between kTe and Fbol. The constant frequency of NBOs with an increase in Fbol suggests that their origin lies in a region strongly influenced by the corona, as explained by the radiation-hydrodynamic model. The origin of FBOs may be attributed to the damped radiation-hydrodynamic mode of radial flow, while the origin of HBOs is supported by the beat-frequency model. 2024 Elsevier B.V.
creator: Thomas N.T.; Lavanya S.; Gudennavar S.B.; Bubbly S.G.
source: Journal of High Energy Astrophysics, Vol-45, pp. 250-261.
publisher: Elsevier B.V.
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 22144048
format: Online
language: English
type: Article
coverage: Thomas N.T., Department of Physics and Electronics, CHRIST University, Karnataka, Bangalore, 560029, India; Lavanya S., Department of Physics and Electronics, CHRIST University, Karnataka, Bangalore, 560029, India; Gudennavar S.B., Department of Physics and Electronics, CHRIST University, Karnataka, Bangalore, 560029, India; Bubbly S.G., Department of Physics and Electronics, CHRIST University, Karnataka, Bangalore, 560029, India

Construction of multifunctional hyaluronic acid modified gold nanoparticles clocked with Irinotecan and indocyanine green: Investigation of chemotherapy and cancer cell imaging
subject: Cancer; Gold nanoparticles; Hyaluronic acid; Imaging; Indocyanine green; Irinotecan
description: To overcome the inherent limits of conventional cancer therapy, there is an immediate need to establish multifunctional drugs that combine accurate diagnosis with treatment. The work describes a small nanocomposite's mild and easy fabrication, including Irinotecan, folic acid, hyaluronic acid, and indocyanine green-integrated gold nanoparticles. The gold nanoparticles with indocyanine green integrated (HA@ICG/Au) were developed in one step for photodynamic treatment and biological fluorescence imaging. Both the drug delivery of Irinotecan and the enhancement of cellular selectivity are achieved by the hyaluronic acid-altered ICG/Au (HA@ICG/Au). To regulate the release of Irinotecan during tumour chemotherapy, the dual-targeted and pH-responsive system known as HA@ICG/Au:FA@IRI was developed. The nanocomposite composed of HA@ICG/Au:FA@IRI had a tiny surface area and was highly efficient at encapsulation and loading drugs. In an acidic milieu, the nanocomposite showed excellent biocompatibility, colloidal stability, photostability, and a rapid cumulative release rate. The improved cellular uptake of HA@ICG/Au:FA@IRI for fluorescence imaging was validated by fluorescence microscopy in vitro. The nanocomposite showed impressive cancer cell death when exposed to laser irradiation using a combination of synergistic chemotherapy and photodynamic treatment (PDT). Taken as a whole, the results show that the nanocomposite was successfully developed to target tumors in two different ways, resulting in a potentially helpful theranostics agent. 2025 Elsevier B.V.
creator: Menon S.V.; Juneja B.; Joshi U.; Faujdar M.; Chinnathambi A.; Alahmadi T.A.; Arulselvan P.; Thangavelu I.
source: Journal of Drug Delivery Science and Technology, Vol-105
publisher: Editions de Sante
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 17732247; CODEN: JDDSA
format: Online
language: English
type: Article
coverage: Menon S.V., Department of Chemistry and Biochemistry, JAIN (Deemed-to-be University), Karnataka, Bangalore, 560069, India; Juneja B., Centre of Research Impact and Outcome, Chitkara University, Punjab, Rajpura, 140417, India; Joshi U., Department of Mechanical Engineering, PIET, Parul University, Gujarat, Vadodara, 391760, India; Faujdar M., Department of Sciences, Vivekananda Global University, Jaipur, 391760, India; Chinnathambi A., Department of Botany and Microbiology, College of Science, King Saud University, PO Box -2455, Riyadh, 11451, Saudi Arabia; Alahmadi T.A., Department of Pediatrics, College of Medicine and King Khalid University Hospital, King Saud University, Medical City, PO Box-2925, Riyadh, 11461, Saudi Arabia; Arulselvan P., Department of Chemistry, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, 602105, India; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India

Deep Learning Based Multi Constraint Hybrid Optimization Algorithm for Transshipment-Based Inventory Routing with Dynamic Demands
subject: Dynamic demands; Inventory routing; Quantum neural network; Snake artificial ecosystem optimization; Transshipments
description: The Inventory-Routing Problem (IRP) is considered a major issue in supply chain management as it comprises two areas: vehicle routing and inventory control. The existing techniqueswere unable to incorporate location details for enhancing the decision-making and it failed to consider the uncertainty of the demands. Hence to solve this issue, a Snake Artificial Ecosystem Optimization (SAEO) algorithm is proposed in this paper. The SAEO algorithm is developed to address the transshipment IRP with dynamic demands by combining the AEO model and SO to enhance the optimizer's performance. Further, a penalty strategy is proposed, where Deep Quantum Neural Network (DQNN) is employed for calculating the penalty for verifying the feasibility of the solution generated in case of violations in model constraints. In addition, the efficiency of the proposed SAEO-DQNN technique is examined by considering metrics, like transportation cost, transshipment cost, and total cost, and it achieved improved values of 0.391, 0.518, and 1.012 when compared to existing techniques such as Genetic Algorithm with Deep Reinforcement Learning (GA + Deep RL) and Kernel Search Multi-vehicle IRP (KSMIRP). The Author(s) 2024.
creator: Sivadevuni S.S.; J N.
source: International Journal of Networked and Distributed Computing, Vol-13, No. 1
publisher: Springer Science and Business Media B.V.
date: 2025-01-01
rights: All Open Access; Gold Open Access
relation: ISSN: 22117938
format: Online
language: English
type: Article
coverage: Sivadevuni S.S., Department of Computer Science and Engineering, School of Engineering and Technology, Christ University, Karnataka, Bangalore, 560001, India; J N., Department of Computer Science and Engineering, School of Engineering and Technology, Christ University, Karnataka, Bangalore, 560001, India

Serendipitous detection of an intense X-ray flare in the weak-line T Tauri star KM Ori with SRG/eROSITA
subject: stars: activity; stars: flare; stars: individual (KM Ori); stars: pre-main sequence; stars: variables: T Tauri; X-rays: stars
description: Weak-line T Tauri stars (WTTS) exhibit X-ray flares, likely resulting from magnetic reconnection that heats the stellar plasma to very high temperatures. These flares are difficult to identify through targeted observations. Here, we report the serendipitous detection of the brightest X-ray flaring state of the WTTS KM Ori in the eROSITA DR1 survey. Observations from SRG/eROSITA, Chandra X-ray Observatory, and XMM-Newton are analysed to assess the X-ray properties of KM Ori, thereby establishing its flaring state at the eROSITA epoch. The long-term (1999-2020) X-ray light curve generated for the Chandra observations confirmed that eROSITA captured the source at its highest X-ray flaring state recorded to date. Multi-instrument observations support the X-ray flaring state of the source, with time-averaged X-ray luminosity reaching at the eROSITA epoch, marking it the brightest and possibly the longest flare observed so far. Such intense X-ray flares have been detected only in a few WTTS. The X-ray spectral analysis unveils the presence of multiple thermal plasma components at all epochs. The notably high luminosity , energy (erg), and the elevated emission measures of the thermal components in the eROSITA epoch indicate a superflare/megaflare state of KM Ori. Additionally, the H line equivalent width of from our optical spectral analysis, combined with the lack of infrared excess in the spectral energy distribution, were used to re-confirm the WTTS (thin disc/disc-less) classification of the source. The long-duration flare of KM Ori observed by eROSITA indicates the possibility of a slow-rise top-flat flare. The detection demonstrates the potential of eROSITA to uncover such rare, transient events, thereby providing new insights into the X-ray activity of WTTS. The Author(s), 2025. Published by Cambridge University Press on behalf of Astronomical Society of Australia.
creator: Ezhikode S.H.; Anilkumar H.; Arun R.; Mathew B.; Jithesh V.; Bhattacharyya S.; Nedhath S.; Cysil T.B.; Muneer S.; Kartha S.S.; Kumar S.P.
source: Publications of the Astronomical Society of Australia, Vol-42
publisher: Cambridge University Press
date: 2025-01-01
rights: All Open Access; Green Open Access
relation: ISSN: 13233580
format: Online
language: English
type: Article
coverage: Ezhikode S.H., Department of Physics and Electronics, CHRIST (Deemed to Be University), Bangalore, India, St. Francis de Sales College (Autonomous), Electronics City, Bengaluru, India; Anilkumar H., Department of Physics and Electronics, CHRIST (Deemed to Be University), Bangalore, India; Arun R., Indian Institute of Astrophysics, Koramangala, Bangalore, India; Mathew B., Department of Physics and Electronics, CHRIST (Deemed to Be University), Bangalore, India; Jithesh V., Department of Physics and Electronics, CHRIST (Deemed to Be University), Bangalore, India; Bhattacharyya S., Department of Physics and Electronics, CHRIST (Deemed to Be University), Bangalore, India, European Organisation for Astronomical Research in the Southern Hemisphere (ESO), Casilla 19001, Santiago, Chile; Nedhath S., Department of Physics and Electronics, CHRIST (Deemed to Be University), Bangalore, India, Indian Institute of Astrophysics, Koramangala, Bangalore, India; Cysil T.B., Department of Physics and Electronics, CHRIST (Deemed to Be University), Bangalore, India; Muneer S., Indian Institute of Astrophysics, Koramangala, Bangalore, India; Kartha S.S., Department of Physics and Electronics, CHRIST (Deemed to Be University), Bangalore, India; Kumar S.P., Indian Institute of Astrophysics, Koramangala, Bangalore, India

Appraisal of prolyl 4-hydroxylase alpha subunit gene polymorphisms in Spondyloepimetaphyseal dysplasia of Handigodu type (SEMDHG)
subject: 4-hydroxyproline; Collagen; Handigodu; Prolyl 4-hydroxylase; Spondyloepimetaphyseal dysplasia
description: Background: The Handigodu variant of Spondyloepimetaphyseal Dysplasia (SEMDHG) is a severe, progressive osteoarthritic disorder characterized by chronic pain and joint degeneration. Clinically, the disorder presents in three distinct phenotypic forms, each exhibiting varying degrees of stature reduction and disease severity. Urine analysis of affected individuals reveals an elevated peptide-bound proline to 4-hydroxyproline ratio relative to controls, suggesting disruptions in collagen metabolism. Given the critical role of prolyl 4-hydroxylase enzymes in stabilizing collagen structure, this study undertook a comprehensive sequence analysis of all three isoforms of prolyl 4-hydroxylase in both affected and unaffected individuals to elucidate potential molecular underpinnings of the disorder. Method: The entire exonic regions and 2000 base pairs upstream of the translation start sites of the P4HA1, P4HA2, and P4HA3 genes were sequenced in a cohort of 300 individuals, comprising 166 affected and 134 unaffected individuals. Results: Sequence analysis of the ? (I), ? (II), and ? (III) subunit genes identified three novel SNPs and a 39-bp deletion variant, in addition to ten previously reported SNPs catalogued in dbSNP. The SNP rs28384495 in P4HA1, the 39-bp deletion variant, and a novel mutation (SNP3) in P4HA3 exhibited significantly different allele frequencies between patients and controls. Genotype association analysis revealed that SNPs in P4HA1 and P4HA3 were associated with Type 2 and Type 3 HD under various genetic models. Notably, all Type 2 HD patients were heterozygous for the 39-bp deletion, whereas all Type 3 HD patients were homozygous for the variant. Haplotype analysis corroborated the findings of the genotype association analysis. Conclusion: This study is the first to account an association between the P4H gene and disease. Further research is needed to evaluate the functional implications of the identified mutations. 2024
creator: Venugopal P.N.; Rao I.A.; Mollick S.A.; Chandrasekar A.
source: Human Gene, Vol-43
publisher: Elsevier B.V.
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 27730441
format: Online
language: English
type: Article
coverage: Venugopal P.N., Anthropological Survey of India, Southern Regional Centre, Karnataka, Mysore, India; Rao I.A., Department of Life Sciences, Christ University, Karnataka, Bengaluru, India; Mollick S.A., Anthropological Survey of India, Southern Regional Centre, Karnataka, Mysore, India; Chandrasekar A., Anthropological Survey of India, Southern Regional Centre, Karnataka, Mysore, India

A Methodological Framework for Descriptive Phenomenological Research
subject: descriptive phenomenology; healthcare research; Husserl; methodological framework; nursing research; phenomenology; qualitative methods
description: Background: Descriptive phenomenological research is crucial in nursing for understanding individuals experiences, perceptions, and relationships, which are essential for person-centered healthcare. However, a common critique is that researchers often use phenomenological methods without fully comprehending their historical and philosophical foundations. Existing literature highlights discrepancies in the application of phenomenological principles by nurse researchers, particularly in their presentation of philosophical underpinnings and methodological details. Aim: This article aims to provide a comprehensive methodological framework for descriptive phenomenological research in nursing, addressing both theoretical and practical aspects to guide novice researchers. Data Sources: This framework synthesizes existing scholarship on descriptive phenomenology. Discussion: Starting from Husserl, this article provides a detailed overview of the history, foundations, and philosophical assumptions of the methodology. It also includes key terms and a comprehensive detailing of all aspects of the research process. Conclusion: This framework enriches existing scholarship by offering a streamlined, step-by-step methodological guide for researchers embarking on descriptive phenomenological studies. It emphasizes the importance of establishing minimum, yet critical criteria for publishing research employing this methodology. Implications for Research: Future nurse researchers are encouraged to enhance methodological transparency in their descriptive phenomenological studies to facilitate rigorous evaluation of method effectiveness and study quality. This framework aims to alleviate potential apprehensions and provide clarity and structure to novice researchers in the field. The Author(s) 2024.
creator: Abraham D.M.; P P.
source: Western Journal of Nursing Research, Vol-47, No. 2, pp. 125-134.
publisher: SAGE Publications Inc.
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 1939459; PubMed ID: 39723632
format: Online
language: English
type: Article
coverage: Abraham D.M., Christ University Bangalore, Karnataka, India; P P., Christ University Bangalore, Karnataka, India

Cross Correlation Between Plasmaspheric Hiss Waves and Enhanced Radiation Levels at Aviation Altitudes
subject: aviation altitudes; dose rates; enhanced radiation; plasmaspheric hiss waves; space hazards; Van Allen radiation belt
description: Enhanced radiation in the Earth's atmosphere can pose serious hazards to pilots, aircraft passengers, and commercial space travelers. Recent results have shown, statistically, that there is a strong correlation between dose rates observed by Automated Radiation Measurements for Aerospace Safety (ARMAS) instruments at aviation altitudes (>9km) and plasmaspheric hiss wave power measured by NASA's Van Allen Probes within the inner magnetosphere. Plasmaspheric hiss waves play a very important role in removing energetic electrons from the Earth's radiation belts by precipitating them into the upper atmosphere. These relativistic electrons generally drift eastwards along closed magnetic drift shells. In this study, we use magnetic conjunction events between ARMAS and the Van Allen Probes to analyze the causality between plasmaspheric hiss waves and enhanced radiation observed at aviation altitude. We specifically study how the size of the conjunction window and a shift in L and MLT of the conjunction window affect the correlation between dose rates and plasmaspheric hiss wave power. This is to determine if the observed enhanced radiation at aviation altitude is indeed caused by the plasmaspheric hiss waves in the inner magnetosphere. The results show that the enhanced radiation levels are only correlated with plasmaspheric hiss waves within conjunction windows of ?1 (Formula presented.) L (Formula presented.) 1 and 0 (Formula presented.) MLT (Formula presented.) 2. The correlation between dose rate and hiss wave power increases slightly if ARMAS is shifted approximately 1hr in MLT to the east of the Van Allen Probes, consistent with the drift trajectory of the electrons precipitating into the atmosphere. 2025. The Author(s).
creator: Aryan H.; Bortnik J.; Tobiska W.K.; Mehta P.; Siddalingappa R.; Hogan B.
source: Space Weather, Vol-23, No. 2
publisher: John Wiley and Sons Inc
date: 2025-01-01
rights: All Open Access; Gold Open Access
relation: ISSN: 15427390
format: Online
language: English
type: Article
coverage: Aryan H., University of California Los Angeles, Atmospheric and Oceanic Sciences, Los Angeles, CA, United States; Bortnik J., University of California Los Angeles, Atmospheric and Oceanic Sciences, Los Angeles, CA, United States; Tobiska W.K., Space Weather Division, Space Environment Technologies, Pacific Palisades, CA, United States; Mehta P., West Virginia University, Mechanical and Aerospace Engineering, Morgantown, WV, United States; Siddalingappa R., West Virginia University, Mechanical and Aerospace Engineering, Morgantown, WV, United States, Department of Computer Science, Christ University, Karnataka, Bangalore, India; Hogan B., Space Weather Division, Space Environment Technologies, Pacific Palisades, CA, United States

A First Report of Docosahexaenoic Acid-Clocked Polymer Enveloped Gold Nanoparticles: A Way to Precision Breast Cancer and Triple Negative Breast Cancer Therapy and Its Apoptosis Induction
subject: apoptosis; breast cancer; docosahexaenoic acid; drug delivery; gold nanoparticles
description: Functionalized gold nanoparticles (GNPs) are extensively utilized in various disciplines due to their excellent bioactivity, biocompatibility, and extended drug half-life, influenced by the ligands and size that are changed on surfaces. In this study, we successfully fabricated GNPs coated with ligands containing docosahexaenoic acid (DHA) and polyethylene glycol (PEG) clocked by a carboxyl group. These nanoparticles are referred to as MPA@GNPs-PEG-DHA. The cytotoxicity results demonstrate that MPA@GNPs-PEG-DHA exhibits superior cell selectivity, explicitly inhibiting the proliferation of breast cancerous cells than noncancerous cell lines. Apoptosis is involved in the reduction of cell proliferation by MPA@GNPs-PEG-DHA, as demonstrated clearly through many assays measuring apoptotic index, including AO/EB staining, DAPI, annexin V-FITC staining, mitochondrial membrane potential (MMP), and reactive oxygen species (ROS) measurement. The efficacy of MPA@GNPs-PEG-DHA in inducing apoptosis was demonstrated by its inhibition of mitochondrial dysfunction by ROS. MPA@GNPs-PEG-DHA has the potential to improve the induction of apoptosis in breast cancerous cells. 2024 Wiley Periodicals LLC.
creator: Khanna L.; Ballal S.; Awasthi K.K.; Singh D.; Chinnathambi A.; Alahmadi T.A.; Abudoleh S.M.; Thangavelu I.
source: Journal of Applied Polymer Science, Vol-142, No. 8
publisher: John Wiley and Sons Inc
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 218995; CODEN: JAPNA
format: Online
language: English
type: Article
coverage: Khanna L., Chitkara Centre for Research and Development, Chitkara University, Himachal Pradesh, Pinjore, India; Ballal S., Department of Chemistry and Biochemistry, JAIN (Deemed-to-be University), Karnataka, Bangalore, India; Awasthi K.K., Department of Sciences, Vivekananda Global University, Jaipur, India; Singh D., Centre of Research Impact and Outcome, Chitkara University, Punjab, Rajpura, India; Chinnathambi A., Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia; Alahmadi T.A., Department of Pediatrics, College of Medicine and King Khalid University Hospital, King Saud University, Medical City, Riyadh, Saudi Arabia; Abudoleh S.M., Faculty of Pharmacy, Middle East University, Amman, Jordan; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, India

Environmental value development among preadolescents: a content analysis of reflective responses
subject: climate change; empathy; Environmental education; environmental values; reflective-thinking
description: Addressing the environmentally detrimental values prevalent in society in the context of rapid climate change is the need of the hour. Combining empathy with cognitive skills such as reflective thinking effectively creates new values among people. The present study attempts to reveal the pattern of environmental value development among 33 preadolescents by reflecting upon the empathy-generating story experiences and the related contents. The study is part of a more extensive quasi-experimental study, and it specifically performs a content analysis on the participants responses in their workbooks. Biospheric nature-related values are the most highly developed, and social justice is the least developed value, implying the need to focus more on the value of social justice. Stories are aids, and reflective thinking and empathetic elicitation are effective techniques for passing environmental values. Empathy generation instead of negative emotions from self-concern and emotion regulation through reflective thinking may be helpful to promote well-being in the context of climate change. Reflective thinking helps environmental value development by enhancing comprehension, emotion regulation, and self-awareness of values, implying a shift from telling the moral of a story to exploring the same through reflective thinking. 2025 Informa UK Limited, trading as Taylor & Francis Group.
creator: Gopinath S.; K.C B.; Kumar A.
source: Reflective Practice
publisher: Routledge
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 14623943
format: Online
language: English
type: Article
coverage: Gopinath S., Department of Psychology, CHRIST (Deemed to be University), Bengaluru, India; K.C B., Department of Psychology, CHRIST (Deemed to be University), Bengaluru, India; Kumar A., Department of Psychology, CHRIST (Deemed to be University), Bengaluru, India

Influence of alkali treatment on physiochemical and morphological properties of palmyra fibers
subject: Alkali treatment; Chemical analysis; Palmyra fibers; Surface morphology; Tensile strength
description: As a part of sustainable development in construction, natural fibers are used as reinforcement in cement composites. The degradation of these natural fibers in matrix has led to growing interest among researchers to enhance the fiber properties by adopting suitable treatment techniques. This research focuses on examining the influence of alkali treatment on various aspects, including the physical, chemical, crystallinity, mechanical and surface characteristics of palmyra fibers. Herein, the palmyra fibers were immersed in alkaline solution for different duration (30 minutes, 60 minutes and 120 minutes) to arrive at optimum treatment period. The investigation utilizes XRD, FTIR, SEM and EDS analysis to gain insights into these properties. The findings indicated that the treatment effectively removed excess amorphous components like extractives, hemicellulose and lignin leading to the increase in crystallinity index and surface roughness. The crystallinity index increased by 11 %, 13 % and 23 % for 30 minutes, 60 minutes and 120 minutes treatment respectively. The water absorption of palmyra fibers reduced by 13 %, 14 % and 14 % for 30 minutes, 60 minutes and 120 minutes treatment duration respectively. Additionally, SEM-EDS exhibited best results for 60 min treatment of fibers, with 38 % increase in Oxygen to Carbon ratio of cellulose compared to untreated fibers. Among the different treatment duration, the 60 minutes treatment duration of fibers in 0.5 M sodium hydroxide solution has exhibited considerable enhancement in properties. These enhancements in palmyra fiber properties post-alkali treatment suggests their potential utility in the reinforcement of composites using alkali treated palmyra fibers. 2024 The Authors
creator: Rai P.S.; Unnikrishnan S.; Chandrashekar A.
source: Industrial Crops and Products, Vol-224
publisher: Elsevier B.V.
date: 2025-01-01
rights: All Open Access; Hybrid Gold Open Access
relation: ISSN: 9266690; CODEN: ICRDE
format: Online
language: English
type: Article
coverage: Rai P.S., Research Scholar, KVG College of Engineering, DK, Sullia, 574327, India; Unnikrishnan S., Christ University, Bengaluru, 560074, India; Chandrashekar A., KVG College of Engineering, DK, Sullia, 574327, India

Polypyrrole functionalized MoS2 for sensitive and simultaneous determination of heavy metal ions in water
description: Assessing heavy metal ion (HMI) contamination to sustain drinking water hygiene is a challenge. Conventional approaches are appealing for the detection of HMIs but electrochemical approaches can resolve the limitations of these approaches, such as tedious sample preparation, high cost, time consuming and the need for trained professionals. Here, an electrochemical approach is developed using a nano-sphered polypyrrole (PPy) functionalized with MoS2 (PPy/MoS2) by square wave anodic stripping voltammetry for the detection of HMIs. The developed sensor can detect Pb2+ with a limit of detection of 0.03 nM and a sensitivity of 36.42 ?A nM?1. Additionally, the PPy/MoS2 sensor was employed for the simultaneous detection of HMIs of Cd2+, Pb2+, Cu2+ and Hg2+. The reproducibility, stability and anti-interference studies confirm that the sensor can be used to monitor HMI contamination of water. 2025 The Royal Society of Chemistry.
creator: Manjunatha Kumara K.S.; Siddiqa A.; Shiva Kumar P.; Lavanya G.; Budagumpi S.; Hegde G.; Nagaraju D.H.; Usha Rani N.
source: RSC Advances, Vol-15, No. 1, pp. 467-476.
publisher: Royal Society of Chemistry
date: 2025-01-01
rights: All Open Access; Gold Open Access
relation: ISSN: 20462069; CODEN: RSCAC
format: Online
language: English
type: Article
coverage: Manjunatha Kumara K.S., Department of Chemistry, School of Applied Sciences, REVA University, Karnataka, Bangalore, 560064, India; Siddiqa A., Department of Chemistry, School of Applied Sciences, REVA University, Karnataka, Bangalore, 560064, India; Shiva Kumar P., Department of Chemistry, School of Applied Sciences, REVA University, Karnataka, Bangalore, 560064, India; Lavanya G., Department of Chemistry, School of Applied Sciences, REVA University, Karnataka, Bangalore, 560064, India; Budagumpi S., Center for Nano and Material Sciences, JAIN (Deemed-to-be-University), Jakkasandra, Karnataka (D), Ramanagar, 562112, India; Hegde G., Centre for Advanced Research and Development (CARD), CHRIST University, Hosur Road, Karnataka, Bangalore, 560029, India; Nagaraju D.H., Department of Chemistry, School of Applied Sciences, REVA University, Karnataka, Bangalore, 560064, India; Usha Rani N., Department of Freshman Engineering, PVP Siddhartha Institute of Technology, Andhra Pradesh, Vijayawada, 520007, India

An exploration of 'pull' and 'push' motivational factors among transgender entrepreneurs
subject: entrepreneurship; India; motivation; self-employment; transgender individual entrepreneur
description: To date, studies have focused on the men and women entrepreneurs and the gender difference in motivations among cisgender entrepreneurs. The study aims to determine whether a transgender individual entrepreneur is motivated through a push motivational factor or a pull motivational factor. This study employs a qualitative approach uses face-to-face interviews and a semi-structured interview with a sample size of 16 transgender entrepreneurs in India. It was found that the participants in this study were motivated by both push and pull factors. The motivational factors, which add to the knowledge of already existing push and pull factors, were to forego begging and commercial sex work, to break stereotypes, to create a business opportunity for other transgender individuals, to earn respect from society, to prove entrepreneurship is non-binary, to be a role model for other transgender individuals and to the society. In contrast, the push motivational factors were the limited opportunities, support received from society, the hijra guru, media, government support, family, friends, landlords, NGOs and another push motivational factor was the exhibitions conducted exclusively for the transgender individual entrepreneurs. 2025 Inderscience Enterprises Ltd.
creator: Sarah P.; Chellaswamy K.P.
source: International Journal of Business and Globalisation, Vol-39, No. 1, pp. 67-82.
publisher: Inderscience Publishers
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 17533627
format: Online
language: English
type: Article
coverage: Sarah P., Department of Commerce, Christ (Deemed to be University), Karnataka, Bangalore, 560029, India; Chellaswamy K.P., Department of Commerce, Christ (Deemed to be University), Karnataka, Bangalore, 560029, India

Electrical transport and magnetoresistance studies on the magnetic moment compensated Mn2V1-xCoxZ (Z=Ga, Al; x=0, 0.25, 0.5, 0.75, 1) Heusler alloys
description: We report the electrical resistivity and magnetoresistance properties of arc-melted Mn2V1-xCoxZ (Z=Ga, Al; x =0, 0.25, 0.5, 0.75, 1) alloys, which possess compensated ferrimagnetic behaviour with high TC when x=0.5. Apart from metallicity, the alloys in the Ga series with x= 0, 0.75, 1 composition showed a positive to negative crossover in the magnetoresistance versus temperature curves. This crossover was absent for Mn2V0.75Co0.25Ga and the fully compensated ferrimagnet Mn2V0.5Co0.5Ga. In contrast to this, Co-substituted Mn2VAl exhibits distinctly different resistive behaviour. While the alloys Mn2VAl and Mn2CoAl exhibit metallic and semiconducting behaviour respectively, the intermediate compositions show a gradual metallic to semiconducting transition as the Co concentration increases. The compensated ferrimagnet Mn2V0.5Co0.5Al showed a mixed transport behaviour of metallic and semiconducting nature with a resistivity minimum at 140 K. In contrast to this mixed response of the arc-melted bulk sample, the Mn2V0.5Co0.5Al melt-spun ribbon shows a clear semiconducting nature throughout the temperature range, indicating that the sample preparation methods could highly influence the electrical properties of the investigated compensated ferrimagnets. 2024 Elsevier B.V.
creator: Midhunlal P.V.; Chelvane J.A.; Babu P.D.; Kumar N.H.
source: Journal of Magnetism and Magnetic Materials, Vol-614
publisher: Elsevier B.V.
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 3048853; CODEN: JMMMD
format: Online
language: English
type: Article
coverage: Midhunlal P.V., Department of Sciences and Humanities, School of Engineering and Technology, Christ University, Karnataka, Bangalore, 560074, India; Chelvane J.A., Defence Metallurgical Research Laboratory, Kanchanbagh (PO), Hyderabad, 500058, India; Babu P.D., UGC-DAE Consortium for Scientific Research, Mumbai Center, 246-C, CFB, BARC Campus, Mumbai, Trombay, 400085, India; Kumar N.H., Department of Physics, Indian Institute of Technology Madras, Chennai, 600036, India

Unfolding the aggression and locus of control paradigm in sportspersons and non-sportspersons
subject: Anger; Combat sports; Non-combat sports; Physical education; Sports psychology
description: The present study investigated Aggression and Locus of Control on Combat Sports Persons, Non-Combat Sports Persons, and Non-Sports Persons. In this study, a sample of 240 individuals (80 Combat sports, 80 Non-Combat Sports & 80 Non-Sportspersons) was used through purposive sampling. The tools administered were the Buss and Perry Aggression Questionnaire by Arnold H. Buss and Mark Perry and Rotters Locus of Control Scale by Julian Rotter respectively. The objective of the study was to investigate Aggression and Locus of Control in males and females from Combat, Non-Combat, and Non-Sports persons. This research also aims to explore the relationship between Aggression and Locus of Control. Mean, t-test, F-value (ANOVA), and correlation have been computed over SPSS-16. Results suggest that males from Combat have higher Aggression than people from non-sports and non-combat sports. There is also a significant difference between non-sports persons and sports people over the Locus of Control, sports persons showed internal locus of control compared to non-sports persons who were higher on external locus of control. The result also indicates a significant relationship between the anger dimension of the Aggression and Locus of Control. 2025 ARD Asociaci Espala.
creator: Marwaha E.B.; Sharma A.; Arora K.
source: Journal of Human Sport and Exercise , Vol-20, No. 1, pp. 144-156.
publisher: Asociacion Espanola de Analisis del Rendimiento Deportivo
date: 2025-01-01
rights: All Open Access; Gold Open Access
relation: ISSN: 19885202
format: Online
language: English
type: Article
coverage: Marwaha E.B., Department of Applied Psychology, Shyama Prasad Mukherji College(w)(), University of Delhi, India; Sharma A., Department of Applied Psychology, Shyama Prasad Mukherji College(w)(), University of Delhi, India; Arora K., Christ Deemed to University, Bangalore, India