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                <text>Osteosarcoma (MG-63) is a type of bone cancer affects mostly adolescents and young adults. Disease-causing microorganisms like Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae and Candida albicans pose serious illness in humans. There is a need to develop multifunctional composite to combat cancer and other most common disease caused by disease causing microorganisms. In this context, BaO2 and pluronic F127, L-Ornithine coated BaO2 (BaO2-PF127-LO) composite have been prepared and characterized by XRD, FTIR, UV-Vis, SEM, HRTEM, EDAX, and XPS analytical techniques. BaO2 and BaO2-PF127-LO were orthorhombic crystalline structure and the crystallite size was found as 32nm for BaO2 and 26nm for modified BaO2 PL studies revealed the green emission observed at 506nm for BaO2-PF127-LO composite which is absent in the case of bare BaO2. Antimicrobial activity of BaO2 and BaO2-PF127-LO was investigated. MTT assay was performed to determine the anticancer potential while the DPPH free radical scavenging assay was carried out to determine the antioxidant potential. The experiment study revealed that the BaO2-PF127-LO exhibited enhanced antimicrobial, antioxidant, and anticancer activity and low toxicity when compared to pristine BaO2. The experimental results revealed that the BaO2-PF127-LO composite holds promising potential for biomedical applications.  The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.</text>
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                <text>Bhran A.A., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11432, Saudi Arabia; Ben Hamida M.B., Deanship of Scientific Research, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, 560029, India; Tadepalli S., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11432, Saudi Arabia</text>
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                <text>In the present study, ?-TCP and NiTi@?-TCP nanocomposite were synthesized using a modified solgel method. DLS analysis revealed hydrodynamic particle sizes of ?290 nm for ?-TCP and ?231 nm for NiTi@?-TCP, suggesting improved dispersion after NiTi modification. Optical studies showed a red shift in UVVis absorption from 321 nm (?-TCP) to 396 nm (NiTi@?-TCP) with a reduced band gap from 3.8 eV to 3.1 eV, indicating enhanced electronic interactions. Morphological analysis using SEM and HRTEM revealed nanoscale particles (?1530 nm) with clear lattice fringes and polycrystalline diffraction patterns. The NiTi@?-TCP nanocomposite exhibited enhanced antibacterial activity against S. aureus, S. pneumoniae, K. pneumoniae, and Escherichia coli, producing inhibition zones of 17, 13, 14, and 12 mm, respectively, compared with approximately 10 mm for pure ?-TCP. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values for S. aureus were 0.3 mg mL? and 0.5 mg mL? for NiTi@?-TCP, respectively, which were lower than those of ?-TCP (MIC 0.5 mg mL?; MBC 0.7 mg mL?). Histidine scavenger experiments demonstrated that reactive oxygen species (ROS) play a dominant role in bacterial inhibition. Biocompatibility studies using L929 fibroblast cells showed high cell viability (&amp;gt;87% at 150 ?g mL?), confirming good cytocompatibility. In contrast, the nanocomposite exhibited enhanced anticancer activity against MG-63 osteosarcoma cells, with an IC?? value of 115 ?g mL?, compared with 138 ?g mL? for ?-TCP. These results demonstrate that NiTi@?-TCP nanocomposite possesses improved antibacterial and anticancer properties while maintaining good biocompatibility, making it a promising multifunctional biomaterial for biomedical and bone-related therapeutic applications.  2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.</text>
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                <text>Alothaim, Abdulaziz S.; Suresh, Mickymaray; ALFaleh, Faleh A.; Alsowayeh, Noorah; Suresh, Kaviya; Thangavelu, Indumathi; Arulselvan, Palanisamy</text>
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                <text>Alothaim A.S., Department of Biology, College of Science Al-Zulfi, Majmaah University, Saudi Arabia; Suresh M., Department of Biology, College of Science Al-Zulfi, Majmaah University, Saudi Arabia; ALFaleh F.A., Department of Biology, College of Science Al-Zulfi, Majmaah University, Saudi Arabia; Alsowayeh N., Department of Biology, College of Science Al-Zulfi, Majmaah University, Saudi Arabia; Suresh K., Department of Pharmaceutics, Sri Ramachandra Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research (DU), Chennai, India; Thangavelu I., Department of Chemistry, CHRIST (Deemed to Be University), Karnataka, Bangalore, India; Arulselvan P., Department of Chemistry, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India</text>
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                <text>Infectious diseases and cancer are two significant groups of diseases attributed to the major death around the globe. There is a need to develop innovative strategies to treat antibiotic resistance bacteria and cancer effectively. In this context, the present work focused on development of calcium oxide (CaO) and CaO modified with chitosan and dopamine nanocomposites (CaOCsDop) as potential antibacterial, anticancer, and antioxidant agents. The prepared nanoparticles were characterized using various characterization techniques. FTIR revealed the functional groups of prepared samples indicating the successful preparation of nanoparticles. XRD revealed the fcc cubic nature of CaO nanoparticles and the crystallite size was found to be 23 nm for CaOCsDOP and 31 nm for CaO nanoparticles. DLS results confirmed the mean particle hydrodynamic size was found as nm for 231.90 CaO and 189.90 nm for CaOCsDOP nanocomposite. The disk diffusion assay was carried out against common pathogenic bacterial strains as Pseudomonas aeruginosa, Klebsiella pneumoniae, Vibrio cholerae, Escherichia coli, and Shigella dysenteriae. MTT assay was carried out to determine the anticancer activity against MOLT-4 cell line, a human acute lymphoblastic leukemia model. The results indicated that CaOCsDOP nanocomposites exhibited enhanced antibacterial and anticancer activities compared with bare CaO nanoparticles, making them a promising multifunctional agent in biomedical applications.  2025 Wiley Periodicals LLC.</text>
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              <elementText elementTextId="219987">
                <text>Journal of Engineering and Applied Science;Volume;72;Issue;1;Article No.;100;</text>
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                <text>&lt;a href="https://doi.org/10.1186/s44147-025-00658-0" target="_blank" rel="noreferrer noopener"&gt;https://doi.org/10.1186/s44147-025-00658-0&lt;/a&gt; &lt;br /&gt;&lt;br /&gt;&lt;a href="https://www.scopus.com/pages/publications/105009984516?origin=resultslist" target="_blank" rel="noreferrer noopener"&gt;https://www.scopus.com/pages/publications/105009984516?origin=resultslist&lt;/a&gt;</text>
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                <text>Xavier L.F., Department of Mechanical and Automobile Engineering, CHRIST University, Karnataka, Bangalore, 560074, India</text>
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                <text>This paper presents a study on the development of carbonaceous battery anode material derived from biomass sources, particularly cornstalk for energy storage applications. The carbonization process was optimized, followed by activation and doping with transition metal oxides like nickel and cobalt to enhance the electrochemical performance of the anode material. Cyclic voltammetry and chronopotentiometry studies were employed to characterize the electrochemical properties, specifically the charge storage behavior of the synthesized materials. Fourier transform infrared spectroscopy spectrum, BrunauerEmmettTeller analysis, and scanning electron microscopy were employed to study the impact of doping, surface area, pore size distribution, and surface morphology. The results indicate that doping with metal oxides significantly improves the conductivity and charge storage capacity of the carbon-based materials, making them promising candidates for sustainable battery applications.  The Author(s) 2025.</text>
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                <text>Anode materials; Biomass-derived carbon; Carbonaceous materials; Cobalt oxide; Cyclic voltammetry; Energy storage; Nickel oxide</text>
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                <text>Development of CeO2ZrO2 bimetallic oxide catalyst for quinoxaline synthesis</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="83666">
                <text>bimetallic; biological activity; ceria; quinoxaline; zirconia</text>
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                <text>In recent years, heterogeneous catalysts have led to environment-friendly transformations with better yields and reusability. Pd, one of the initial metals employed in heterogeneous organic synthesis, suffered from limitations like its high cost. This justifies the need for development of catalysts with abundant, low-cost metals, which has been receiving a lot of attention in the scientific community. In this work, a bimetallic oxide catalyst, CeO2ZrO2, is synthesized by a solgel route. The structure and morphology of the catalyst are investigated using X-ray diffraction, scanning electron microscopy, energy-dispersive X-ray analysis, thermogravimetric analysis, BrunauerEmmettTeller measurements, and temperature-programmed desorption. It is utilized for obtaining quinoxaline derivatives at room temperature. 2,3-Diphenylquinoxaline is obtained via a simple condensation reaction between 1,2-diaminobenzene and 1,2-diketones, catalyzed by CeO2(50)ZrO2(50) with 87% yield in 15 min. Quinoxalines are known for their biological and therapeutic activities; hence, they are essential molecules. The biological activity of the synthesized quinoxaline derivatives has been evaluated against bacterial and fungal strains.  2023 Society of Chemical Industry.  2023 Society of Chemical Industry.</text>
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              <elementText elementTextId="83668">
                <text>Anand S.; Devi K. R. S.</text>
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            <elementTextContainer>
              <elementText elementTextId="83669">
                <text>Journal of Chemical Technology and Biotechnology, Vol-99, No. 2, pp. 426-436.</text>
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            <name>Publisher</name>
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              <elementText elementTextId="83670">
                <text>John Wiley and Sons Ltd</text>
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                <text>&lt;a href="https://doi.org/10.1002/jctb.7544" target="_blank" rel="noreferrer noopener"&gt;https://doi.org/10.1002/jctb.7544&lt;/a&gt;
&lt;br /&gt;&lt;br /&gt;&lt;a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85176958407&amp;amp;doi=10.1002%2Fjctb.7544&amp;amp;partnerID=40&amp;amp;md5=7d7fac8749f245bdf4c0b770a2d12bc8" target="_blank" rel="noreferrer noopener"&gt;https://www.scopus.com/inward/record.uri?eid=2-s2.0-85176958407&amp;amp;doi=10.1002%2fjctb.7544&amp;amp;partnerID=40&amp;amp;md5=7d7fac8749f245bdf4c0b770a2d12bc8&lt;/a&gt;</text>
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              <elementText elementTextId="83673">
                <text>Restricted Access</text>
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                <text>ISSN: 2682575; CODEN: JCTBD</text>
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                <text>Anand S., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India; Devi K. R. S., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India</text>
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          <element elementId="50">
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            <description>A name given to the resource</description>
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              <elementText elementTextId="75855">
                <text>Development of classical swine fever virus E2-protein based indirect ELISA for detection of antibodies against the virus in pigs</text>
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            </elementTextContainer>
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          <element elementId="49">
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            <description>The topic of the resource</description>
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              <elementText elementTextId="75856">
                <text>Classical swine fever; CSFV; E2; ELISA</text>
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              <elementText elementTextId="75857">
                <text>Classical swine fever (CSF) is an economically important and highly contagious disease of pigs caused by CSF virus, genus Pestivirus. Serological diagnosis of the disease is highly valuable for surveillance and thereby containment of spread of the disease. In this study, we have demonstrated the development of CSFV envelope glycoprotein E2-based indirect ELISA (E2-iELISA) for the detection of CSFV specific antibodies. The full-length E2 protein was expressed in E. coli and the purified protein was used as a coating antigen in indirect ELISA for detecting CSFV specific antibodies in pigs. A panel of 506 pig sera samples was used to validate the ELISA and the results were highly comparable to the results obtained with the commercial antibody detection kit (PrioCHECK CSFV Ab kit). The in-house E2-iELISA demonstrated high diagnostic sensitivity (95.4%) and specificity (95.5%), highlighting its potential application for sero-surveillance or monitoring of the disease in the swine population.  The Author(s), under exclusive licence to Springer Nature B.V. 2024.</text>
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              <elementText elementTextId="75858">
                <text>Gopinath S.; Hosamani M.; Joseph B.V.; Patil S.S.</text>
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                <text>Background: In the somatoform and dissociative spectrum, family functioning has been poorly researched based on the search in PubMed, Google Scholar, Science Direct, PROQUEST, EBSCO and Cochrane Reviews. In Psychogenic Non-Epileptic Seizures (PNES) primarily, family functioning has been understood as a comparison between Epileptic Seizures (ES) and PNES. However, an attempt to study different aspects of family functioning and its ability to influence the newlinemanifestation of the disorder is yet to be made. Methods: This study attempted to understand different family functions qualitatively by interviewing both the patients and family members of these patients. Nine patients and seven families of these patients participated in the study. Braun and Clarke s thematic model was used. Latent thematic analysis was used to analyse the data. Based on the analysis, major and sub-themes were used to develop family intervention and a family psychoeducational model. Both were developed with the help of the GUIDED Checklist to report health interventions; the TIDieR format and Delphi newlinetechnique was used to collect the expert opinion of the developed intervention. newlineResults: Two sets of results and analyses were compiled with qualitative data, that is, for patients and families. Major themes and sub-themes were developed for both, including family interaction, attachment, poor communication, structural-systemic aspects, distressful family aspects, negative newlineexpressed emotions, cultural aspects, nature of the illness, family s views of the illness and coping mechanisms. These themes indicated the importance of family functioning and its impact on the manifestation of the disorder. newlineConclusion: The researcher concludes that family dysfunction can impact the manifestation of the disorder. Hence, an additional family intervention or psychoeducation is essential for holistic newlinetreatment.</text>
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