582
20
16481
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Dublin Core
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Title
A name given to the resource
Articles
Article
Faculty Publications -Articles
Dublin Core
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Title
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PCR and Bio-signature for data confidentiality and integrity in mobile cloud computing
Subject
The topic of the resource
Bio-signature; Data security; DNA cryptography; Mobile cloud computing (MCC); Polymerase chain reaction (PCR); Primers
Description
An account of the resource
Cloud computing technology got relevance as computing paradigm, which delivers massively scalable computing technologies based on the Internet for the organizations. Mobile Cloud Computing (MCC) allows users more possibilities to access services conveniently. But data security and privacy issues still act as barriers for adoption to cloud technology when dealing with confidential data. Encryption techniques play a significant role in ensuring data security in the Cloud. Various data encryption techniques have been evolved till the date of which DNA Computing techniques got wider acceptance due to biological complexity and computational properties of DNA. These features can be exploited to solve data security issues in MCC. This paper highlights the security issues in the MCC and proposes biocomputing solution approaches to address data security. A methodology is proposed based on the principle concepts of polymerase chain reaction and primer generation for ensuring data confidentiality and integrity. The security analysis of the proposed cryptosystem is evaluated by theoretical analysis, complexity and probability analysis. Formal analysis of the proposed protocol is done using Scyther and all the modeled claims are validated and positive results are obtained. 2018 The Authors
Creator
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Sukumaran S.C.; Misbahuddin M.
Source
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Journal of King Saud University - Computer and Information Sciences, Vol-33, No. 4, pp. 426-435.
Publisher
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King Saud bin Abdulaziz University
Date
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2021-01-01
Identifier
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<a href="https://doi.org/10.1016/j.jksuci.2018.03.008" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.jksuci.2018.03.008</a>
<br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85044331689&doi=10.1016%2Fj.jksuci.2018.03.008&partnerID=40&md5=afb2fbdb6aee97382c415e0d2da57c1f" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85044331689&doi=10.1016%2fj.jksuci.2018.03.008&partnerID=40&md5=afb2fbdb6aee97382c415e0d2da57c1f</a>
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All Open Access; Gold Open Access
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A related resource
ISSN: 13191578
Format
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Online
Language
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English
Type
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Article
Coverage
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Sukumaran S.C., Dept. of Computer Science, Christ (Deemed to be University), Bengaluru, 560029, India; Misbahuddin M., Computer Networks & Internet Engineering (CNIE) Division, Centre for Development of Advanced Computing, Bengaluru, 560100, India
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Dublin Core
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Title
A name given to the resource
Conference Papers
Conference Paper
Faculty Publications- Conference Papers
Dublin Core
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Title
A name given to the resource
PCRS: Personalized Course Recommender System Based on Hybrid Approach
Subject
The topic of the resource
E-learning; Knowledge Modelling; Ontology; Personalization; Recommendation
Description
An account of the resource
The traditional system of selecting courses to carry out research work is time consuming, risky and a tedious task, that not only badly affect the performance but the learning experience of a researcher as well. Therefore, choosing appropriate courses in seminal years could help to do research in a better way. This Study presents a recommender system that will suggest and guide a learner in selecting the courses as per their requirement. The Hybrid methodology has been used along with ontology to retrieve useful information and make accurate recommendations. Such an approach may be helpful to learners to increase their performance and improve their satisfaction level as well. The proposed recommender systems would perform better by mitigating the weakness of basic individual recommender systems. 2018 The Authors. Published by Elsevier B.V.
Creator
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Gulzar Z.; Leema A.A.; Deepak G.
Source
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Procedia Computer Science, Vol-125, pp. 518-524.
Publisher
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Elsevier B.V.
Date
A point or period of time associated with an event in the lifecycle of the resource
2018-01-01
Identifier
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<a href="https://doi.org/10.1016/j.procs.2017.12.067" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.procs.2017.12.067</a>
<br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85040664066&doi=10.1016%2Fj.procs.2017.12.067&partnerID=40&md5=109e1b40fdd856ca31b0f31aa3c04b02" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85040664066&doi=10.1016%2fj.procs.2017.12.067&partnerID=40&md5=109e1b40fdd856ca31b0f31aa3c04b02</a>
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All Open Access; Gold Open Access
Relation
A related resource
ISSN: 18770509
Format
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Online
Language
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English
Type
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Conference paper
Coverage
The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant
Gulzar Z., BSAR Crescent University, Chennai, India; Leema A.A., BSAR Crescent University, Chennai, India; Deepak G., Christ Univerisy, Bangalore, India
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Dublin Core
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Title
A name given to the resource
Conference Papers
Conference Paper
Faculty Publications- Conference Papers
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
PE-v-SVR based Architecture to Predict and Prevent Low and Slow-Rate DDoS Attacks using Machine Learning
Subject
The topic of the resource
cyber threats; Cybersecurity; DDoS attacks; Entropy; Predictive models; Regression
Description
An account of the resource
Distributed Denial of Service (DDoS) attacks continue to emerge; low and slow attacks pose a serious threat. These small-scale attacks often evade traditional security protections and increase the risk of long-term outages and loss of service. Our research aims to develop effective predictive models and strategic defences to detect and mitigate slow DDoS attacks. The proposed model combines Power Spectral entropy and V-Support Vector Regression. More importantly, the version achieves the first-class error price in the variety of zero to at least one, demonstrating its effectiveness in detecting and predicting DDoS attacks. Research results show the effectiveness of the proposed design using PSD (power spectral density) entropy and V-SVR. The best mean square error obtained further confirms the ability of the model in this context. V-SVR in low and sluggish DDoS assaults. 2024 Bharati Vidyapeeth, New Delhi.
Creator
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Chhettri D.; George F.J.; Nair A.M.; Alapatt B.P.
Source
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Proceedings of the 18th INDIAcom; 2024 11th International Conference on Computing for Sustainable Global Development, INDIACom 2024, pp. 1612-1616.
Publisher
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Institute of Electrical and Electronics Engineers Inc.
Date
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2024-01-01
Identifier
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<a href="https://doi.org/10.23919/INDIACom61295.2024.10498399" target="_blank" rel="noreferrer noopener">https://doi.org/10.23919/INDIACom61295.2024.10498399</a>
<br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85191695656&doi=10.23919%2FINDIACom61295.2024.10498399&partnerID=40&md5=75aa15129b743699d94569b991947f29" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85191695656&doi=10.23919%2fINDIACom61295.2024.10498399&partnerID=40&md5=75aa15129b743699d94569b991947f29</a>
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Restricted Access
Relation
A related resource
ISBN: 978-938054451-9
Format
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Online
Language
A language of the resource
English
Type
The nature or genre of the resource
Conference paper
Coverage
The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant
Chhettri D., Christ (Deemed to Be University), Bangalore, India; George F.J., Christ (Deemed to Be University), Bangalore, India; Nair A.M., Christ (Deemed to Be University), Bangalore, India; Alapatt B.P., Christ (Deemed to Be University), Bangalore, India
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https://archives.christuniversity.in/files/original/a1d7ca5d5852a51943c6951311578b83.jpg
050af8f80c7f1283d6f60aedaee6ee5f
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Exhibit
Still Image
A static visual representation. Examples include paintings, drawings, graphic designs, plans and maps. Recommended best practice is to assign the type Text to images of textual materials.
Original Format
The type of object, such as painting, sculpture, paper, photo, and additional data
Engraved solid pure silver ingots, layered with pure 24-carat gold
Physical Dimensions
The actual physical size of the original image
Stamp size is 29.50 mm x 39.50 mm
Gold Replica is 2.2mm thick with diamond cut perforations
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Peacock Motif
Subject
The topic of the resource
Stamp ingot collection
Description
An account of the resource
Peacock Motif: 19th Century Minakari is a set of 2 postage stamps which was issued on 29 November, 2003 by the Department of Posts which commemorate the multi-dimensional bilateral relation and diplomatic ties between India (Peacock) and France (Rooster). Indian stamp depicts a peacock from a 19th century piece of jewellery crafted in Minakari tradition.
Creator
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Hallmark Group Limited
Source
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Pride of India Collection
Publisher
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Authority of India Post
Date
A point or period of time associated with an event in the lifecycle of the resource
2003-12-21
Format
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JPG
Type
The nature or genre of the resource
Image
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Faculty Publications
Article
Faculty Publications -Articles
Dublin Core
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Creator
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Raja, Ponmani; Sujatha, S.; Prajoon, P.
Title
A name given to the resource
Peak-to-Average Power Ratio (PAPR) Aware Signal Shaping in UFMC: An Adaptive Orthogonal Precoding and Gaussianized Companding Approach
Date
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01-01-2026
Source
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International Journal of Advanced Science and Engineering;Volume;12;Issue;3;pp.6084-6103
Identifier
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<a href="https://doi.org/10.29294/IJASE.12.3.2026.6084-6103" target="_blank" rel="noreferrer noopener">https://doi.org/10.29294/IJASE.12.3.2026.6084-6103</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105034293562?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105034293562?origin=resultslist</a>
Coverage
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Raja P., Department of Electronics & Communication Engineering, Christ (Deemed to be University), Bangalore, 560074, India; Sujatha S., Department of Electronics & Communication Engineering, Christ (Deemed to be University), Bangalore, 560074, India; Prajoon P., Department of Electronics & Communication Engineering, Jyothi Engineering College, Kerala, 679531, India
Description
An account of the resource
Universal Filtered Multi-Carrier (UFMC) is a promising waveform for 5G and beyond wireless systems due to its superior spectral localization and low-latency characteristics; however, its high Peak-to-Average Power Ratio (PAPR) significantly degrades power amplifier efficiency and causes nonlinear distortion and out-of-band (OOB) emissions. To address these limitations, this paper proposes an Adaptive Hybrid Orthogonal Precoding with Gaussianized Companding (AHO-PCG) framework for PAPR-aware UFMC transmission. The proposed approach integrates adaptive orthogonal precoding, Gaussianized Dynamic Companding (GDC), and Selective Subcarrier Companding (SSC) within a joint optimization loop to balance PAPR reduction, signal fidelity, and spectral containment. Gaussianization reshapes the signal amplitude distribution to suppress extreme peaks, while adaptive precoding dynamically selects suitable orthogonal transforms based on signal characteristics, and SSC limits nonlinear processing to dominant peak-contributing subcarriers. Simulation results under 3GPP LTE-compliant parameters using QPSK, 16-PSK, and 64-QAM demonstrate that AHO-PCG achieves up to 4.4 dB PAPR reduction at a CCDF of 10-3, reduces EVM to 2.9%, suppresses OOB emissions to 42 dBm, and improves BER by up to an order of magnitude compared to baseline UFMC. These gains are achieved with a modest processing overhead, making the framework suitable for real-time 5G baseband implementations and extensible to future 6G waveform designs. 2026 Mahendrapublications.com, All rights reserved.
Subject
The topic of the resource
Adaptive Hybrid Orthogonal Precoding, Gaussianized Companding; Amplifiers; Energy Efficacy; Selective subcarrier companding; Universal Filtered Multi-Carrier
Publisher
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Mahendra Publications
Relation
A related resource
ISSN: 23495359;
Language
A language of the resource
English
Type
The nature or genre of the resource
Article
Rights
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All Open Access; Bronze Open Access
Format
The file format, physical medium, or dimensions of the resource
online
-
Dublin Core
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Title
A name given to the resource
Faculty Publications
Article
Faculty Publications -Articles
Dublin Core
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Creator
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Vaithianathan, Krishnakumar; Pernabas, Julian Benadit; Lamani, Manjunath Ramanna; Venkatachalam, K.; Askar, S.S.; Abouhawwash, Mohamed
Title
A name given to the resource
Pearson correlation-based clustering with collaborative task allocation in 5G Industrial Internet of Things divergent health networks
Date
A point or period of time associated with an event in the lifecycle of the resource
01-01-2025
Source
A related resource from which the described resource is derived
Scientific Reports;Volume;15;Issue;1;Article No.;43344;
Identifier
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<a href="https://doi.org/10.1038/s41598-025-27366-2" target="_blank" rel="noreferrer noopener">https://doi.org/10.1038/s41598-025-27366-2</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105024216086?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105024216086?origin=resultslist</a>
Coverage
The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant
Vaithianathan K., Department of Computer Engineering, Karaikal Polytechnic College, Varichikudy, Puducherry, Karaikal, 609609, India; Pernabas J.B., Department of Computer Science and Engineering, CHRIST (Deemed to be University), Kengeri Campus, Karnataka, Bangalore, 560074, India; Lamani M.R., Department of Computer Science and Engineering, Moodlakatte Institute of Technology Kundapura, Karnataka, Moodalkatte, 576217, India; Venkatachalam K., Department of Applied Cybernetics, Faculty of Science, University of Hradec Krov Hradec Krov 50003, Czech Republic; Askar S.S., Department of Statistics and Operations Research, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia; Abouhawwash M., Department of Industrial and Systems Engineering, King Fahd University of Petroleum & Minerals, Dhahran, 31261, Saudi Arabia, Interdisciplinary Research Center for Smart Mobility and Logistics (IRC-SML), King Fahd University of Petroleum & Minerals, Dhahran, 31261, Saudi Arabia
Description
An account of the resource
Simultaneous task allocation is crucial for enhancing service quality in Industrial Internet of Things (IIoT) environments. The distribution and management of tasks remain among the biggest challenges in the IIoT era. Efficient allocation strategies are needed to enable transparent network configurations and maximize task throughput. Although recent methods address the dynamic management of objects, they often overlook the correlations between tasks and their associated functionalities. This paper introduces a novel Connected Harmonical Adaptive Task Allocation (CHATA) model for IIoT health networks to ensure fair task distribution. CHATA leverages similarity measures of object functionalities to identify the most suitable object to perform each task. Simulations conducted in NS-3 demonstrate that CHATA achieves up to 90% allocation efficiency in 5G Radio Access Technologies IIoT health environments and significantly outperforms recent approaches in task assignment performance. The Author(s) 2025.
Subject
The topic of the resource
5G; Clustering; IIoT-health; Task allocation
Publisher
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Nature Research
Relation
A related resource
ISSN: 20452322;
Language
A language of the resource
English
Type
The nature or genre of the resource
Article
Rights
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All Open Access; Gold Open Access; Green Open Access
Format
The file format, physical medium, or dimensions of the resource
online
-
https://archives.christuniversity.in/files/original/7354dcf880cd006795dee4423c04e073.pdf
3fbc0ec74b783c278bd9735a5ba2908e
Dublin Core
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Title
A name given to the resource
MPHIL
Mphil
Mphil Thesis
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Pedagogic Use of Commercial Feature Film in Christ University Deanery of Humanities and Social Sciences
Creator
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Pushpendra Kumar Bali Aasita
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
Source
A related resource from which the described resource is derived
Media Studies
Description
An account of the resource
This thesis discusses the use of commercial feature film as a pedagogical tool in the classrooms within the Deanery of Humanities and Social Sciences of Christ University. It investigates the purpose of using films as pedagogy in higher education and the reasons behind its popularity among both teachers and students.
Triangulation method was used for gathering data combining qualitative and quantitative methods such as pretesting posttesting, survey and in depth interviews. Information was gathered by using interview schedule and online questionnaires from teachers and students of the Deanery of Humanities and Social Sciences to analyze the plausible impact of feature films as pedagogy in subjects taught.
The findings suggest that films are popular pedagogical tool and are effective if used along with discussions post screening.
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Articles
Article
Faculty Publications -Articles
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Pedagogical exploration for generation z students: Experiments using student-developed video case studies, gamification, student-developed case simulation and a movie reflection exercise in an organizational behaviour course
Subject
The topic of the resource
Generation Z students; Innovative pedagogy; Management education in India; Positive learning outcomes
Description
An account of the resource
This paper will focus on three experiments performed while teaching undergraduate and graduate students using innovative pedagogy. In all three studies, the purpose was to understand how effective these pedagogical tools were in generating enthusiasm and engaging the students in the learning process. In study 1, teams developed and presented video case studies on the organizational behaviour themes studied in the course, applying them to practical scenarios. Later, the facilitators conducted a modified gamification quiz based on the video case studies, and the quiz results were considered to be the actual assessment of the students learning process. In study 2, student teams were asked to brain-storm and develop case simulations based on actual incidents encountered by those students who had work experience. In study 3, the undergraduate students were shown the classic movie 12 Angry Men as a means of learning about team decision-making processes. They reflected on and discussed the movie in relation to theory. Feedback collected at the end of each study conveyed that students experienced high levels of enthusiasm and engagement with positive learning outcomes. 2020 NeilsonJournals Publishing.
Creator
An entity primarily responsible for making the resource
Annamalai S.; Sebastian S.
Source
A related resource from which the described resource is derived
Journal of Organizational Behavior Education, Vol-13, pp. 143-168.
Publisher
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NeilsonJournals Publishing
Date
A point or period of time associated with an event in the lifecycle of the resource
2020-01-01
Identifier
An unambiguous reference to the resource within a given context
<a href="" target="_blank" rel="noreferrer noopener"></a>
<br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115881860&partnerID=40&md5=278dd921e0a9a90cb0609a987bc52526" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115881860&partnerID=40&md5=278dd921e0a9a90cb0609a987bc52526</a>
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Restricted Access
Relation
A related resource
ISSN: 16497627
Format
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Online
Language
A language of the resource
English
Type
The nature or genre of the resource
Article
Coverage
The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant
Annamalai S., Christ University, Bangalore, India; Sebastian S., Christ University, Bangalore, India
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Dublin Core
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Title
A name given to the resource
Book Chapter
Book Chapter
Faculty Publications- Book Chapter
Dublin Core
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Title
A name given to the resource
Pedagogy: The 1947 Partition Archive: A contemporary pedagogical resource to teach the rival history of the partition of India
Description
An account of the resource
[No abstract available]
Creator
An entity primarily responsible for making the resource
Bisht P.; Sharma M.
Source
A related resource from which the described resource is derived
The Routledge Companion to Literature and Social Justice, pp. 499-511.
Publisher
An entity responsible for making the resource available
Taylor and Francis
Date
A point or period of time associated with an event in the lifecycle of the resource
2023-01-01
Identifier
An unambiguous reference to the resource within a given context
<a href="https://doi.org/10.4324/9781003246428-43" target="_blank" rel="noreferrer noopener">https://doi.org/10.4324/9781003246428-43</a>
<br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85176859466&doi=10.4324%2F9781003246428-43&partnerID=40&md5=3cb6a10e0bb8759c56613ba9b3e151d8" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85176859466&doi=10.4324%2f9781003246428-43&partnerID=40&md5=3cb6a10e0bb8759c56613ba9b3e151d8</a>
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Restricted Access
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A related resource
ISBN: 978-100324642-8; 978-103215942-3
Format
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Online
Language
A language of the resource
English
Type
The nature or genre of the resource
Book chapter
Coverage
The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant
Bisht P., Christ University, Delhi, India; Sharma M., Christ University, Delhi, India
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Conference Papers
Conference Paper
Faculty Publications- Conference Papers
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Pedestrian crossing behaviour between transport terminals
Subject
The topic of the resource
Behaviour; Crosswalks; Pedestrians; Transport
Description
An account of the resource
Pedestrians possess special requirements for protecting their privacy while interacting with other users of a transport network. There exists a need in order to obtain a deeper knowledge of pedestrian traffic behaviour in between transport terminals. When different transportation terminals come closer, there will be an increased pedestrian flow caused due to change in modes used. The main aim was to analyses the general pedestrian behaviour while crossing a road and to find out different human factors which affect this behaviour. The crossing patterns were observed and also the chances of conflict with vehicles. The paper brought out the fact that the pedestrians always preferred different types of crossings. These varied with the gender and age of the pedestrians and also with luggage carrying or not. There seemed to be a greater flow of pedestrians during the peak hours and then they faced difficulty in crossing due to heavy traffic. Crosswalks are locations in which pedestrians are exposed to fewer rights of accident prevention even though they may approach the roadway and be alert of approaching traffic. Pedestrian unlawful crossing attitude is a crucial factor inside area issue of safety on the road. Thus, there is a requirement to take more steps towards bringing safety. 2023 Author(s).
Creator
An entity primarily responsible for making the resource
Jamwal S.; Gupta C.; Devi S.R.; Ganesh V.N.; Sankar P.; Parthiban P.
Source
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AIP Conference Proceedings, Vol-2690
Publisher
An entity responsible for making the resource available
American Institute of Physics Inc.
Date
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2023-01-01
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<a href="https://doi.org/10.1063/5.0120102" target="_blank" rel="noreferrer noopener">https://doi.org/10.1063/5.0120102</a>
<br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85152706621&doi=10.1063%2F5.0120102&partnerID=40&md5=973d71aa4f8335de588569a513b21f92" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85152706621&doi=10.1063%2f5.0120102&partnerID=40&md5=973d71aa4f8335de588569a513b21f92</a>
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All Open Access; Bronze Open Access
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A related resource
ISSN: 0094243X; ISBN: 978-073544334-1
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Online
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English
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Conference paper
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Jamwal S., Department of English, Government College of Education, Jammu and Kashmir, Jammu, India; Gupta C., Christ University, Karnataka, Bengaluru, India; Devi S.R., Department of English, School of Liberal Arts and Special Education, Kalasalingam Academy of Research and Education, Tamilnadu, Krishnankoil, India; Ganesh V.N., Department of Civil Engineering, PSG Institute of Technology and Applied Research, Coimbatore, India; Sankar P., Department of Civil Engineering, Vinayaka Mission's Kirupananda Variyar Engineering College, Tamilnadu, Salem, India; Parthiban P., Department of Civil Engineering, Jyothi Engineering College, Kerala, Thrissur, India
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Faculty Publications
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Faculty Publications -Articles
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Praghash, K.; Chalasani, Vidyadhari; Balan, Santhosh Kumar; Daniya, T.
Title
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Pediatric brain tumor segmentation and classification framework using SGC-U-NET and ARC-DEEP-CNN
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01-01-2025
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International Journal of Information Technology (Singapore);
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<a href="https://doi.org/10.1007/s41870-025-02966-3" target="_blank" rel="noreferrer noopener">https://doi.org/10.1007/s41870-025-02966-3</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105025465649?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105025465649?origin=resultslist</a>
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Praghash K., Department of Electronics and Communication Engineering, Christ University, Bengaluru, India; Chalasani V., Department of Information Technology, Gokaraju Rangaraju Institute of Engineering and Technology, Bachupally, Hyderabad, India; Balan S.K., Department of Computer Science and Engineering, Guru Nanak Institute of Technology, Ranga Reddy (District), Ibrahimpatnam, Telangana, 501506, India; Daniya T., Department of CSE (AI & ML), GMR Institute of Technology, Rajam, Andhra Pradesh, Vizianagaram, India
Description
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Timely and precise pediatric Brain Tumor (BT) classification is challenging in the prevailing studies owing to the lack of growth rate calculation. Therefore, this paper proposes a growth rate-aware intelligent BT classification using child Magnetic Resonance Imaging (MRI) based on Arcsin Deep Convolutional Neural Network (Arc-Deep-CNN). Initially, the child's MRI is collected and then pre-processed for angle correction, resolution improvement, skull removal, and edge sharpening to improve the image quality. Meanwhile, the binary image dilation is done in the postpre-processing for accurate tumor location identification using the Central Limit Theorem-based Battle Royale Optimization Algorithm (CLT-BROA). From the pre-processed images, the wavelet features are extracted to improve the detection rate. Based on the tumor-identified images, pre-processed images, and extracted features, a robust Shuffled Group Convolutional layer added U-Net (SGC-U-Net) significantly segments the normal brain, benign, core, and malignant tumors affected brain. Then, the 3D tumor reconstruction is done by performing splitting, feature extraction, and growth rate calculation. Finally, a novel Arc-Deep-CNN proficiently classifies the BT into Medulloblastoma, Glioma, and Meningioma tumors with respect to the growth rate. The proposed Arc-Deep-CNN achieved maximum accuracy and minimum training time of 98.77% and 52136ms, respectively, showing impressive performance in pediatric BT classification. Bharati Vidyapeeth's Institute of Computer Applications and Management 2025.
Subject
The topic of the resource
Arcsin deep convolutional neural network (Arc-Deep-CNN); Brain tumor; Central limit theorem-based battle royale optimization algorithm (CLT-BROA); Magnetic resonance imaging (MRI); Medulloblastoma; Shuffled group convolutional layer added U-net (SGC-U-Net)
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Springer Science and Business Media B.V.
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ISSN: 25112104;
Language
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English
Type
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Article
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Restricted Access; Hardcopy may be available in the library
Format
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online
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Title
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Faculty Publications
Article
Faculty Publications -Articles
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Hemanth, Hinnakki; Paari, Kuppusamy Alagesan
Title
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Pediococcus pentaceous-mediated fermentation of Gracilaria corticate: A sustainable reutilisation of renewable resource to enhance its nutritional profile, optimised through response surface methodology for improved growth and pathogenic resistance in Oreochromis niloticus
Date
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01-01-2026
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Research Journal of Biotechnology;Volume;21;Issue;1;pp.297-308
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<a href="https://doi.org/10.25303/211rjbt2970308" target="_blank" rel="noreferrer noopener">https://doi.org/10.25303/211rjbt2970308</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105025362573?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105025362573?origin=resultslist</a>
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Hemanth H., Department of Life Sciences, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bengaluru, 560029, India; Paari K.A., Department of Life Sciences, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bengaluru, 560029, India
Description
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Seaweed, as a functional food and a sustainable alternative to synthetic additives, is gaining attention. It can enhance the nutritive value, improve antioxidant properties and mitigate oxidative stress induced by pathogens. This study investigates the utilisation of fermented seaweeds in feed formulations to reduce oxidative stress, improve fish health and enhance disease resistance. Seaweeds Gracilaria corticate, rich in bioactive compounds such as polyphenols and antioxidants, were fermented using probiotic Pediococcus pentosaceus MK459540. Nile tilapia (Oreochromis niloticus) was fed a diet supplemented with fermented seaweed, which indicates lower levels of Superoxide Dismutase (SOD), Glutathione (GSH) and Glutathione-S-Transferase (GST) activities compared to control and non-fermented seaweeds when challenged with Vibrio harveyi, Aeromonas hydrophila and a mixture of both pathogens. These findings highlight the potential of seaweed, a sustainable and renewable marine resource in advancing aquaculture practices by promoting fish health and immunity. 2026, World Researchers Associations. All rights reserved.
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Box-Behnken model; Functional foods; Solid state fermentation
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World Researchers Associations
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ISSN: 9736263;
Language
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English
Type
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Article
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Restricted Access; Hardcopy may be available in the library
Format
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online
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Title
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Articles
Article
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Title
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PEDOT decorated with PTIR nanoclusters on carbon fiber paper toward electrocatalytic reduction of a hypertensive drug olmesartan medoxomil
Description
An account of the resource
A facile electrochemical sensor was developed by electrochemical deposition of PtIr nanoparticles on poly(3,4ethylenedioxythiophene) (PEDOT) modified carbon fiber paper electrode (CFP). The modified electrodes were characterized by Field emission scanning electron microscopy (FESEM) with energy-dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), RAMAN spectroscopy, Fourier transform infrared spectroscopy (FTIR) and electroanalytical techniques. PtIr-PEDOT modified CFP electrode was used successfully in the determination of an anti-hypertensive prodrug Olmesartan medoxomil (OM) at femtomolar (fM) level for the first time. Under optimal conditions, the prepared electrochemical sensor has shown broad linear range between 0.001 pM and 0.220 pM and superior detection limit of 3.42 fM was observed based on Differential pulse voltammetric (DPV) study. In addition, the designed electrochemical sensor was successfully demonstrated as a novel platform in the electrochemical determination of OM in human urine and pharmaceutical samples. 2018 The Electrochemical Society.
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Akshaya K.B.; Vinod T.P.; Nidhin M.; Varghese A.; George L.
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Journal of the Electrochemical Society, Vol-165, No. 13, pp. B582-B595.
Publisher
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Electrochemical Society Inc.
Date
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2018-01-01
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<a href="https://doi.org/10.1149/2.0671813jes" target="_blank" rel="noreferrer noopener">https://doi.org/10.1149/2.0671813jes</a>
<br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85067402870&doi=10.1149%2F2.0671813jes&partnerID=40&md5=d7e8cb5488197a67c7d97e67f95bf826" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85067402870&doi=10.1149%2f2.0671813jes&partnerID=40&md5=d7e8cb5488197a67c7d97e67f95bf826</a>
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Restricted Access
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A related resource
ISSN: 134651; CODEN: JESOA
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Online
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English
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Article
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Akshaya K.B., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560 029, India; Vinod T.P., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560 029, India; Nidhin M., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560 029, India; Varghese A., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560 029, India; George L., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560 029, India
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Articles
Article
Faculty Publications -Articles
Dublin Core
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Title
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PEDOT-Doped Mesoporous Nanocarbon Electrodes for High Capacitive Aqueous Symmetric Supercapacitors
Subject
The topic of the resource
carbon matrix; carbon nanoparticles; electrode fabrication; FESEM/ATR-FTIR/XRD/BET/BJH/CV/GCD/EIS; mesopores; nanocomposites; onion peels pyrolysis; poly(3,4-ethylenedioxythiophene); supercapacitors
Description
An account of the resource
Poly(3,4-ethylenedioxythiophene) (PEDOT) and PEDOT-functionalized carbon nanoparticles (f-CNPs) were synthesized by in situ chemical oxidative polymerization and pyrolysis methods. f-CNP-PEDOT nanocomposites were prepared by varying the concentration of PEDOT from 1 to 20% by weight (i.e., 1, 2.5, 5, 10, and 20 wt%). Several characterization techniques, such as field-emission scanning electron microscopy (FESEM), attenuated total reflectance-Fourier transform infrared (ATR-FTIR), X-ray diffraction (XRD), N2 BrunauerEmmettTeller (BET) and BarrettJoynerHalenda (BJH) analyses, as well as cyclic voltammetry (CV), galvanostatic charge discharge (GCD), and electrochemical impedance spectroscopy (EIS), were applied to investigate the morphology, the crystalline structure, the N2 adsorption/desorption capability, as well as the electrochemical properties of these new synthesized nanocomposite materials. FESEM analysis showed that these nanocomposites have defined porous structures, and BET surface area analysis showed that the standalone f-CNP exhibited the largest surface area of 801.6 m2/g, whereas the f-CNP-PEDOT with 20 wt% exhibited the smallest surface area of 116 m2/g. The BJH method showed that the nanocomposites were predominantly mesoporous. CV, GCD, and EIS measurements showed that f-CNP functionalized with 5 wt% PEDOT had a higher capacitive performance compared to the individual f-CNPs and PEDOT constituents, exhibiting an extraordinary specific capacitance of 258.7 F/g, at a current density of 0.25 A/g, due to the combined advantage of enhanced electrochemical activity induced by PEDOT doping, and highly developed porosity of f-CNPs. Symmetric aqueous supercapacitor devices were fabricated using the optimized f-CNP-PEDOT doped with 5 wt% of PEDOT as active material, exhibiting a high capacitance of 96.7 F/g at 1.4 V, holding practically their full charge, after 10,000 chargedischarge cycles at 2 A/g, thus providing the highest electrical electrodes performance. Hereafter, this work paves the way for the potential use of f-CNP-PEDOT nanocomposites in the development of high-energy-density supercapacitors. 2024 by the authors.
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Taj M.; Bhat V.S.; Sriram G.; Kurkuri M.; Manohara S.R.; Padova P.D.; Hegde G.
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Nanomaterials, Vol-14, No. 14
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Multidisciplinary Digital Publishing Institute (MDPI)
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2024-01-01
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<a href="https://doi.org/10.3390/nano14141222" target="_blank" rel="noreferrer noopener">https://doi.org/10.3390/nano14141222</a>
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All Open Access; Gold Open Access; Green Open Access
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ISSN: 20794991
Format
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Online
Language
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English
Type
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Article
Coverage
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Taj M., Nano-Composites and Materials Research Laboratory, Department of Physics, Siddaganga Institute of Technology (Affiliated to Visvesvaraya Technological University, Belagavi), Karnataka, Tumakuru, 572103, India, Department of Physics, HKBK College of Engineering, Karnataka, Bengaluru, 560045, India; Bhat V.S., Department of Materials Science, Mangalore University, Karnataka, Mangalagangotri, 574199, India; Sriram G., School of Chemical Engineering, Yeungnam University, Gyeongsan, 38541, South Korea; Kurkuri M., Centre for Research in Functional Materials (CRFM), Jain (Deemedtobe University), Jain Global Campus, Karnataka, Bengaluru, 562112, India; Manohara S.R., Nano-Composites and Materials Research Laboratory, Department of Physics, Siddaganga Institute of Technology (Affiliated to Visvesvaraya Technological University, Belagavi), Karnataka, Tumakuru, 572103, India; Padova P.D., Consiglio Nazionale delle Ricerche, Istituto di Struttura della Materia (CNRISM), Via Fosso del Cavaliere, 100, Rome, 00133, Italy, Istituto Nazionale di Fisica NucleareLaboratori Nazionali di Frascati (INFNLNF), Via E. Fermi, 54, Frascati, 00040, Italy; Hegde G., Centre for Advanced Research and Development, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India, Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India
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Title
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Faculty Publications
Book Chapter
Faculty Publications- Book Chapter
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Singha, Ranjit; Yogesh Kanna, Sathyamoorthy
Title
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Peer Influence on Students Online Addiction Behaviors: Implications for Prevention Strategies Through Multidimensional Addiction Behavior Scale
Date
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01-01-2025
Source
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Students Online Risk Behaviors: Psychoeducational Predictors, Outcomes, and Prevention;pp.1-19
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<a href="https://doi.org/10.4018/979-8-3693-4191-9.ch001" target="_blank" rel="noreferrer noopener">https://doi.org/10.4018/979-8-3693-4191-9.ch001</a> <br /><br /><a href="https://www.scopus.com/pages/publications/105007381340?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/105007381340?origin=resultslist</a>
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Singha R., Christ University, India; Yogesh Kanna S., Christ University, India
Description
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This chapter explores how peer influence affects students online addiction behaviours, emphasizing peer pressure, social norms, and modelling. It outlines the risks and protective factors in peer interactions, supported by empirical evidence, and considers moderating factors such as peer group dynamics and individual traits. The chapter proposes prevention strategies, including educational programs, peer- led initiatives, and institution- based efforts. It also highlights the Multidimensional Addiction Behaviour Scale (MABS) as a critical tool for assessing addiction across five dimensions-Psychological, Biological, Social and Environmental, Cognitive and Behavioral, Motivation and Readiness for change. MABS is invaluable for detecting, preventing, and intervening in digital addiction by offering comprehensive insights into how peer dynamics influence online behaviours and supporting the development of targeted strategies for healthier digital habits. 2025 by IGI Global Scientific Publishing.
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IGI Global
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ISBN: 979-836934192-6; 979-836934191-9;
Language
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English
Type
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Book chapter
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Restricted Access; Hardcopy may be available in the library
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Dublin Core
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Title
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Articles
Article
Faculty Publications -Articles
Dublin Core
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Title
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Peers, Parents and Families as agents of influence on adolescents perspectives towards people with Mental Health Problems: Mental Health Professionals Views
Subject
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Adolescents; Attitudes; Mental health professionals; Peers experiencing mental health problems; Stigma
Description
An account of the resource
Purpose: This study aims to explore mental health professionals views on adolescent attitudes towards their peers with mental health problems and the influence of parental, familial and societal environments on these attitudes. Design/methodology/approach: A qualitative research design was used. Semi-structured interviews were conducted with seventeen mental health professionals in Bangalore, India, with at least two years of experience working with adolescents. Thematic analysis was used to analyze the interview data. Findings: Mental health professionals reported diverse adolescent attitudes towards peers with mental health issues, ranging from support to bullying and exclusion. Family dynamics, peer influence and societal stigma were identified as significant factors shaping these attitudes. Research limitations/implications: The remote interviews during the pandemic limited access to non-verbal cues and work settings. The study focused on professionals' views from Bangalore, not capturing the diverse needs of adolescents across India. Additionally, practitioners from urban settings might not represent the challenges of their rural counterparts. The high concentration of female participants hinders generalisability. Variable interview lengths and participant openness might introduce bias, likely influenced by experience and views on mental health awareness. Practical implications: The findings underscore that adolescents' views on peer mental health are crucial for mental health professionals to design targeted interventions and support systems. Implementing programs that raise mental health awareness and reduce stigma can benefit schools and communities. Social implications: This study highlights the necessity of a holistic strategy to tackle adolescent mental health. Creating supportive peer environments, encouraging open family communication, and combating societal stigma can foster a more inclusive and mentally healthy society for adolescents. Originality/value: This study contributes to the growing body of research on adolescent mental health by providing insights into professionals views of peer attitudes. It highlights the need for interventions addressing family stigma, promoting open communication and using social media for awareness. 2024, Emerald Publishing Limited.
Creator
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A.S M.; N.T S.
Source
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Journal of Public Mental Health, Vol-23, No. 4, pp. 316-329.
Publisher
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Emerald Publishing
Date
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2024-01-01
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<a href="https://doi.org/10.1108/JPMH-04-2024-0048" target="_blank" rel="noreferrer noopener">https://doi.org/10.1108/JPMH-04-2024-0048</a>
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Restricted Access
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ISSN: 17465729
Format
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Online
Language
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English
Type
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Article
Coverage
The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant
A.S M., School of Psychological Sciences, Christ University, Bangalore, India; N.T S., Department of Psychology School of Psychological Sciences, CHRIST (Deemed to be University), Bangalore, India
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Articles
Article
Faculty Publications -Articles
Dublin Core
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Title
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PEGylated Platinum Nanoparticles: A Comprehensive Study of Their Analgesic and Anti-Inflammatory Effects
Subject
The topic of the resource
Analgesic property; Anti-inflammatory Property; Cytotoxicity; DPPH assay; Platinum nanoparticles; Polyethylene glycol
Description
An account of the resource
Pain and inflammation are common symptoms of a majority of the diseases. Chronic pain and inflammation, as well as related dreadful disorders, remain difficult to control due to a lack of safe and effective medications. In this work, biocompatible platinum nanoparticles with significant analgesic and anti-inflammatory action were synthesized through a wet chemical method using polyethylene glycol-400 as a capping agent and sodium borohydride as a reducing agent. The average particle size of these Pt nanospheres was determined to be 3.26 nm using TEM analysis, and X-ray diffraction confirmed their face-centered cubic crystalline structure. Fourier transform infrared and UV-visible spectroscopy confirm that Pt-NPs are coated with the PEG-400 molecule. The significantly negative zeta potential value (?26.8 mV) indicates the stability of the produced nanoparticles. In vitro cytotoxicity studies on normal cell lines show nontoxic behavior with over 96% cell viability at 100 ?g/mL of the test sample. In vitro assays of inhibition of protein denaturation and DPPH free radical scavenging elucidated the anti-inflammatory and antioxidant properties of PEGylated Pt NPs with promising EC50 values 57.99 and 9.324 ?g/mL, respectively. In vivo animal trials confirmed that PEG-capped Pt-NPs are more effective than conventional medicines. The in vivo hot plate assay for the analgesic study shows a maximum response time of 14.5 1.22 s (92.54% analgesia) at a dosage of 50 mg/kg and 13.8 0.71 s (86.05% analgesia) at a dosage of 25 mg/kg after 180 and 240 min of administration, respectively. In the rat paw edema model for anti-inflammatory activity, the PEG-capped Pt NPs exhibit significant inhibitory action, with the maximum percentage of edema inhibition at a dosage of 50 mg/kg identical to that of the aspirin-based standard medication administered at a higher dosage of 100 mg/kg, resulting in 42% inhibition, suggesting a versatile solution for inflammation and persistent pain. 2025 American Chemical Society.
Creator
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Waliaveettil F.A.; Jose J.; Anila E.I.
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ACS Applied Bio Materials, Vol-8, No. 1, pp. 628-641.
Publisher
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American Chemical Society
Date
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2025-01-01
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<a href="https://doi.org/10.1021/acsabm.4c01498" target="_blank" rel="noreferrer noopener">https://doi.org/10.1021/acsabm.4c01498</a>
<br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85215382018&doi=10.1021%2Facsabm.4c01498&partnerID=40&md5=4de439a70d17da2b455df9c022dd0bff" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85215382018&doi=10.1021%2facsabm.4c01498&partnerID=40&md5=4de439a70d17da2b455df9c022dd0bff</a>
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ISSN: 25766422; PubMed ID: 39746938
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Online
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English
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Article
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Waliaveettil F.A., Department of Physics and Electronics, Christ University, Karnataka, Bengaluru, 560029, India; Jose J., Division of Microbiology, Department of Biosciences, Rajagiri College of Social Sciences (Autonomous), Kerala, Cochin, 683104, India; Anila E.I., Department of Physics and Electronics, Christ University, Karnataka, Bengaluru, 560029, India
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Faculty Publications
Article
Faculty Publications -Articles
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Waliaveettil, Felicia Aswathy; Jose, Jiya; Anila, E.I.
Title
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PEGylated Platinum Nanoparticles: A Comprehensive Study of Their Analgesic and Anti-Inflammatory Effects
Date
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01-01-2025
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ACS Applied Bio Materials;Volume;8;Issue;1;pp.628-641
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<a href="https://doi.org/10.1021/acsabm.4c01498" target="_blank" rel="noreferrer noopener">https://doi.org/10.1021/acsabm.4c01498</a> <br /><br /><a href="https://www.scopus.com/pages/publications/85215382018?origin=resultslist" target="_blank" rel="noreferrer noopener">https://www.scopus.com/pages/publications/85215382018?origin=resultslist</a>
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Waliaveettil F.A., Department of Physics and Electronics, Christ University, Karnataka, Bengaluru, 560029, India; Jose J., Division of Microbiology, Department of Biosciences, Rajagiri College of Social Sciences (Autonomous), Kerala, Cochin, 683104, India; Anila E.I., Department of Physics and Electronics, Christ University, Karnataka, Bengaluru, 560029, India
Description
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Pain and inflammation are common symptoms of a majority of the diseases. Chronic pain and inflammation, as well as related dreadful disorders, remain difficult to control due to a lack of safe and effective medications. In this work, biocompatible platinum nanoparticles with significant analgesic and anti-inflammatory action were synthesized through a wet chemical method using polyethylene glycol-400 as a capping agent and sodium borohydride as a reducing agent. The average particle size of these Pt nanospheres was determined to be 3.26 nm using TEM analysis, and X-ray diffraction confirmed their face-centered cubic crystalline structure. Fourier transform infrared and UV-visible spectroscopy confirm that Pt-NPs are coated with the PEG-400 molecule. The significantly negative zeta potential value (?26.8 mV) indicates the stability of the produced nanoparticles. In vitro cytotoxicity studies on normal cell lines show nontoxic behavior with over 96% cell viability at 100 ?g/mL of the test sample. In vitro assays of inhibition of protein denaturation and DPPH free radical scavenging elucidated the anti-inflammatory and antioxidant properties of PEGylated Pt NPs with promising EC50 values 57.99 and 9.324 ?g/mL, respectively. In vivo animal trials confirmed that PEG-capped Pt-NPs are more effective than conventional medicines. The in vivo hot plate assay for the analgesic study shows a maximum response time of 14.5 1.22 s (92.54% analgesia) at a dosage of 50 mg/kg and 13.8 0.71 s (86.05% analgesia) at a dosage of 25 mg/kg after 180 and 240 min of administration, respectively. In the rat paw edema model for anti-inflammatory activity, the PEG-capped Pt NPs exhibit significant inhibitory action, with the maximum percentage of edema inhibition at a dosage of 50 mg/kg identical to that of the aspirin-based standard medication administered at a higher dosage of 100 mg/kg, resulting in 42% inhibition, suggesting a versatile solution for inflammation and persistent pain. 2025 American Chemical Society.
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Analgesic property; Anti-inflammatory Property; Cytotoxicity; DPPH assay; Platinum nanoparticles; Polyethylene glycol
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American Chemical Society
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ISSN: 25766422;
Language
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English
Type
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Article
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Restricted Access; Hardcopy may be available in the library
Format
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online
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Title
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Articles
Article
Faculty Publications -Articles
Dublin Core
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Pemetrexed loaded gold nanoparticles as cytotoxic and apoptosis inducers in lung cancer cells through ROS generation and mitochondrial dysfunction pathway
Subject
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apoptosis; gold nanoparticles; lung cancer; mitochondrial damage; Pemetrexed; ROS generation
Description
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Supramolecular nanoparticles containing peptides and drugs have recently gained recognition as an effective tumor treatment drug delivery system. A multitarget drug termed pemetrexed is effective against various cancers, including nonsmall cell lung cancer. The work aims to establish the capability of pemetrexed gold nanoparticles (PEM-AuNPs) to induce apoptosis and explore molecular changes. X-ray diffraction, Fourier-transform infrared spectroscopy, ultravioletvisible spectroscopy, scanning electron microscope, and transmission electron microscope were used to investigate the synthesized nanoparticles. The MTT assay was utilized to investigate the anticancer properties of PEM-AuNPs at varying concentrations (50, 100, and 200M). PEM-AuNPs demonstrated a decrease in cell viability with 55.87%, 43.04%, and 25.59% for A549 cells and 54.31%, 37.40%, and 25.84% for H1299 cells at the respective concentrations. To assess apoptosis and perform morphological analysis, diverse biochemical staining techniques, including acridine orange-ethidium bromide and 4?,6-diamidino-2-phenylindole nuclear staining assays, were employed. Additionally, 2?,7?-dichlorofluorescein diacetate staining confirmed the induction of reactive oxygen species generation, while JC-1 staining validated the impact on the mitochondrial membrane at the IC50 concentration of PEM-AuNPs. Thus, the study demonstrated that the synthesized PEM-AuNPs exhibited enhanced anticancer activity against both A549 and H1299 cells. 2024 International Union of Biochemistry and Molecular Biology, Inc.
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Baby Shakila P.; Periasamy T.; Alarfaj A.A.; Arulselvan P.; Ravindran R.; Suriyaprakash J.; Thangavelu I.
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Biotechnology and Applied Biochemistry, Vol-71, No. 4, pp. 779-790.
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John Wiley and Sons Inc
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2024-01-01
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<a href="https://doi.org/10.1002/bab.2576" target="_blank" rel="noreferrer noopener">https://doi.org/10.1002/bab.2576</a>
<br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85187516810&doi=10.1002%2Fbab.2576&partnerID=40&md5=4ab787b1c57b49a449e5fd39401baee6" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85187516810&doi=10.1002%2fbab.2576&partnerID=40&md5=4ab787b1c57b49a449e5fd39401baee6</a>
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Restricted Access
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ISSN: 8854513; PubMed ID: 38475937; CODEN: BABIE
Format
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Online
Language
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English
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Article
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Baby Shakila P., Department of Biochemistry, Vivekanandha College of Arts and Sciences for Women (Autonomous), Tiruchengode, Tamilnadu, Namakkal, India; Periasamy T., Department of Biochemistry, Muthayammal College of Arts and Science (Autonomous), Namakkal, India; Alarfaj A.A., Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia; Arulselvan P., Department of Chemistry, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India; Ravindran R., Preclinical Department, Faculty of Medicine, Universiti Kuala Lumpur, Royal College of Medicine Perak, Ipoh, Malaysia; Suriyaprakash J., Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices, School of Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou, China; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, India
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https://archives.christuniversity.in/files/original/ba104d68d7c3a9231b03d84b5942783d.jpg
0b6dfeeadbd8dbf97f5aef738454f6b9
Dublin Core
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Patents
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Patent
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Patent
Patent
Patents
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Pen mouse/14-02
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Computer Science
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Patent Number: 365494-001, Applicant: Ritwika Das Gupta.
Creator
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Samanta, Debabrata.
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<a href="https://drive.google.com/file/d/1h-1ymgMvhIAgAy1tjlGDm_Vh91Bm0LrE/view" target="_blank" title="Pen mouse/14-02" rel="noreferrer noopener">https://drive.google.com/file/d/1h-1ymgMvhIAgAy1tjlGDm_Vh91Bm0LrE/view</a>
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Intellectual Property India
Date
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2022-05-22
Language
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English
Type
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Patent