Browse Items (5511 total)
Sort by:
-
Synthesis and Multifaceted Exploration of 4-Phenylpiperidin-4-ol Substituted Pyrazole: Photophysical Insights with Biological Activity
In this study, we successfully synthesized a pyrazole derivative, specifically 4-phenylpiperidin-4-ol substituted pyrazole (CHP), through the reaction of Grignard reagents in combination with pyrazole. This newly synthesized molecule was subjected to a comprehensive evaluation for both its photophysical and biological applications. Notably, CHP exhibited promising invitro antifungal and antibacterial activities, primarily attributed to the presence of the 4-phenylpiperidin-4-ol moiety and resulting component contributed to an enhanced absorption rate of lipids, thereby improving the pharmacological activity of CHP. This correlation between structure and function was further supported by the outcomes of structure-activity relationship studies. Additionally, we conducted in silico studies to examine the molecular interactions of the synthesized molecule with key proteins, including DNA Gyrase, Lanosterol 14 ?-demethylase, and KEAP1-NRF2. The results unveiled robust binding interactions at specific sites within these proteins, indicating potential therapeutic relevance. Furthermore, the photophysical properties of the synthesized compounds were thoroughly investigated using the ab-initio technique. This involved the determination of ground state optimization and HOMO-LUMO energy levels, all calculated with the DFT-B3LYP-6-31G(d) basis set. The assessment of the theoretically estimated HOMO-LUMO value provided insights into the global chemical reactivity descriptors, revealing that the synthesized molecule boasts a highly electronegative and electrophilic index. Taken together, our findings suggest that pyrazole derivatives with 4-phenylpiperidin-4-ol substitutions exhibit promising applications in both photophysical and biological contexts. 2024 Ghaferah H. Al-Hazmi et al., published by Sciendo. -
Moisture-Sensitive Fe2O3 Nanoparticle-Based Magnetic Soft Actuators
Multifunctional soft robots are emerging as a new-generation intelligent device for challenging environments. To meet the requirements of smart applications and soft robotics, developing a soft actuator capable of multiple functions and mechanical deformation is essential. In this study, we designed a free-standing magnetic soft actuator constructed from iron oxide (Fe2O3) nanoparticles and poly(vinyl alcohol) (PVA), that responds to both moisture and magnetic fields. We used computational modeling (density functional theory and ab initio molecular dynamics) to explain the experimental findings demonstrating the deformation and high-bending angle (?150), which is about twice as large under combined moisture and magnetic field exposure compared to their individual effect. Additionally, a flower-shaped soft robot was designed by using the continuous bending deformation of the actuator in response to moisture changes, performing directional bending in an ambient environment. These findings demonstrate the materials sensitivity to moisture and magnetic fields, opening up new possibilities for designing responsive structures in the smart device industry. 2024 American Chemical Society. -
Hepatoprotective activity of Peltophorum pterocarpum leaf and bark in the isoniazid and rifampicin-induced hepatotoxic rats
Background: In recent years, various phytomedicines have been used in the treatment of hepatic disorders. The aim of this study is to find out whether Peltophorum pterocarpum bark and leaves can help rats that have been exposed to isoniazid and rifampicin-induced hepatotoxicity. Materials and Methods: The rats were divided into 10 groups each with 6 rats. The liver damage is induced by isoniazid and rifampicin. The leaf and bark of P. pterocarpum extracted with ethanol are freshly mixed in sterile water (100, 200 and 400 mg/kg body weight), and given to rats orally in the early morning as a single dosage per day until the study period. The animals were sacrificed and the tissue and serum samples were collected for further investigations. Results: The liver damage induced by isoniazid and rifampicin altered the various biochemical parameters levels, but after the treatment of P. pterocarpum barks and leaves the levels were significantly altered when compared to the negative control rats. The drug silymarin was used as a standard. Conclusion: The extracts have the protective effect of liver markers and membrane-bound enzymes against the toxin-treated rats. This result highlights the hepatoprotective properties of the leaves and barks of the plant in a similar manner and the formulation (Group 10) have high beneficial effects than other groups. 2024 -
Ferrocenyl aniline modified electrode for the electrochemical synthesis of 2-(4-methoxyphenyl)-1H-benzo[d]imidazole
Ferrocenyl aniline is an excellent catalyst used conventionally for heterocyclic syntheses. The use of ferrocenyl aniline, in the presence of electropolymerized thiophene-3-acetic acid (TAA) on carbon fibre paper is novel and found to be an exceptional electrocatalyst, for the synthesis of a proven anti-fungal, anti-proliferative and anti-bacterial, 2-(4-methoxyphenyl)-1H-benzo[d]imidazole. The electrode performance was examined with activity studies and EIS, along with surface characterizations including optical profilometry, FE-SEM, FT-IR and XPS. The synthesis was performed in a single-cell three electrode system, using platinum as counter and saturated calomel electrode (SCE) as the reference, with ethanol as the electrolyte and lithium perchlorate supporting electrolyte. The reaction was performed with o-phenylenediamine and anisaldehyde as starting materials at ambient temperature and pressure, at 1.35 V constant potential for 3 h, and product was isolated and purified using column chromatography to obtain 91% yield and characterized with GCMS and NMR. This synthesis method is noteworthy, due to its environmentally friendly performance, and high yield for a benzimidazole derivative that is pharmacologically vital. 2024 -
THE ANALYSIS OF THE FLOW OF BLOOD IN A STENOSED ARTERY THROUGH SIMULATION: A COMPARISON AMONG VARIOUS NON-NEWTONIAN MODELS
This paper focuses on the dual quality of blood, Newtonian and non-Newtonian, in particular by exploring the energy curves. Careful investigation of the dual property of blood has been made by considering two different geometries to represent a stenosed arterial segment. We present a cautious assessment of non-Newtonian blood rheology impacts in arterial stream simulations by coupling the Newtonian and non-Newtonian models. The flow of energy through the two flow dimensions is meticulously investigated using velocity (kinetic energy), pressure, and wall shear stress (pressure energy). Besides, the proper implementation of an interface boundary condition (IBC) was emphasized to ensure consistency with the flow conditions downstream of a backward-facing step. The integration of the Newtonian and non-Newtonian models adjoins the novelty of the current research. The energy curves are obtained by implementing five different non-Newtonian models to designate a suitable non-Newtonian model for blood flow investigations. The combination of the non-Newtonian models enforced in this research is novel and particular attention is paid to the energy curves obtained. The conclusion was to elect the Carreau model as a suitable non-Newtonian rheological model for the blood flow study. This study was able to finalize the fact that the coupling of Newtonian and non-Newtonian models is necessary to obtain accurate results. For the sinusoidal waveform considered for the velocity, Carreau and the Power law models yield better results, eliminating the other non-Newtonian models from the list. With a better inlet condition imposed in the form of the Fourier series for pressure and velocity, the Carreau model yields the best results. 2024 World Scientific Publishing Company. -
Mentha spicata assisted AgCuO nanocomposite enables anti-diabetic and vitamin-C sensing activities
Diabetes mellitus (DM), a multifactorial chronic health condition, affects a sizable portion of the global population, and more people are expected to contract it in the future, according to the World Health Organisation (WHO). Diabetes mellitus can be treated with conventional drugs, but most of the medications have a variety of side effects. The use of nanocomposites (NCs) to treat diabetes has been prioritized in this scenario. In this study, AgCuO NCs were synthesized using a green method using Mentha spicata leaf extract and their physicochemical properties were investigated with a variety of analytical techniques. According to an extensive in vivo and in vitro analysis of the biological activities of as-synthesized AgCuO NCs, AgCuO NCs possess effective antibacterial, anti-diabetic, and anti-hyperlipidemic characteristics. When AgCuO NCs are administered to STZ-induced animals in a concentration-based manner, the blood levels of inflammatory and liver marker enzymes are reduced and antioxidant enzyme levels are increased. Besides, AgCuO NCs exhibit excellent sensing activity with a limit of detection of 86 nM against Vitamin-C. This study reveals that AgCuO NCs derived from Mentha spicata may, therefore, prove to be a very successful anti-diabetic and biosensor candidate in the future. 2024 Elsevier B.V. -
Assessing the Skill Sets from the NEP Policy 2020: Scale Development and Validation
Purpose: The central aspect of this paper is the National Education Policy (NEP) 2020, an education-based policy in the Indian context. The article captured the opportunities from the perspective of the skill set it offers to its important stakeholders, students; the current research has aimed to propose and validate an instrument to measure the skill set identified from the NEP document and academic expertise, which could be used to measure students skill-based performance. Design/Methodology/Approach: The first section used EFA to establish four skill sets: Employability Skills, Communal-Based Skills, Social and Emotional Skills, and Individualistic Skills. The CFA model was further deployed to confirm the factors; the study was administered to a sample of 820 students from various commerce and management colleges from South and North Bangalore. Findings: The research results could be applied to evaluate the effectiveness of skill sets on students performance to create holistic education. Originality: The first step is to develop and validate scales for measuring skill sets under NEP 2020. Second, in accordance with the pupils order of priority, to close the gap between the talents stated and those observed. Research Limitations/Implications: The study was conducted only with students of commerce and management disciplines in Bangalore. Practical Implications: NEP has placed a greater emphasis on competency development and skill enhancement, which aids in the development of higher-order cognitive, social-emotional, and 21st-century abilities necessary for employment in the future. NEP gave greater autonomy to students to choose their learning pathway and develop skill sets, which are likely to make them job creators, thereby giving rise to the entrepreneurial culture. Social Implications: To cultivate an aspirational student body, it is critical to instill the necessary skill sets in pupils. Policymakers and decision-makers could then organize their courses using these skill sets. 2024, Associated Management Consultants Pvt. Ltd.. All rights reserved. -
Nutritional Value, Fatty Acid and Phytochemical Composition, and Antioxidant Properties of Mysore Fig (Ficus drupacea Thunb.) Fruits
Ficus drupacea is a fruit-bearing tree that is distributed in Southeast Asia and Australia. The objective of this research was to ascertain the following with regard to ripened fruits: (i) their nutritional value, (ii) their mineral status, (iii) the fatty acid composition of fruit and seed oil, (iv) their phytochemical makeup, and (v) their antioxidant properties. The ripened fruits contained 3.21%, 3.25%, 0.92%, 1.47%, and 2.20% carbohydrate, protein, fat, ash, and fiber, respectively. Fruits had an energy content of 30.18 kcal/100 g. In terms of mineral content, the fruit was rich in potassium, magnesium, calcium, and nitrogen, with values of 21.03, 13.24, 11.07, and 4.13 mg/g DW. Iron, zinc, manganese, and boron had values of 686.67, 124.33, 114.40, and 35.78 g/g DW, respectively. The contents of oxalate and phytate were 14.44 and 2.8 mg/g FW, respectively. The fruit and seed oil content were 0.67 and 8.07%, respectively, and the oils physicochemical properties were comparable to those of fig fruit and seed oils. Omega-3 (?-linolenic acid), omega-6 (linoleic acid), and omega-9 (oleic acid) fatty acids were abundant in the oils. Fruit extracts in acetone, methanol, and water have greater concentrations of phenolics, flavonoids, and alkaloids. The 2,2-diphenyl-2-picrylhydrazyl, total antioxidant activity, and ferric reducing antioxidant power assays demonstrated increased antioxidant activities in close correlation with the higher concentrations of phenolics, flavonoids, and alkaloids. The results of this study demonstrate that the fruits of F. drupacea are a strong source of nutrients and phytochemicals, and they merit more investigation and thought for possible uses. 2024 by the authors. -
Deep learning framework for stock price prediction using long short-term memory
Forecasting stock prices is always considered as complicated process due to the dynamic and noisy characteristics of stock data influenced by external factors. For predicting the stock market, several approaches have been put forward. Many academics have successfully forecasted stock prices using soft computing models. Recently, there has been growing interest in applying deep learning techniques in combination with technical indicators to forecast stock prices, attracting attention from both investors and researchers. This paper focuses on developing a reliable model for anticipating future stock prices in one day advance using Long Short-Term Memory (LSTM). Three steps make up the suggested model. The approach begins with ten technical indicators computed from previous data as feature vectors. The second phase involves data normalization to scale the feature vectors. Finally, in the third phase, the LSTM model analyzes the closing price for the next day using the normalized characteristics as input. Two stock markets, NASDAQ and NYSE are chosen to evaluate the efficacy of the developed model. To demonstrate how effective the new model is in making predictions, its performance is compared to earlier models. Comparing the suggested model to other models, the findings revealed that it had a high level of prediction accuracy. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024. -
An efficient hybrid approach for numerical study of two-dimensional time-fractional Cattaneo model with Riesz distributed-order space-fractional operator along with stability analysis
In this article, we study and analyze the two-dimensional time-fractional Cattaneo model with Riesz space distributed-order. To obtain approximate solutions of this type of fractional model the combined and effective numerical approach based on the ADI Galerkin method and the Legendre spectral method used the ADI Galerkin numerical method uses the finite difference approach. The ADI Galerkin numerical method is used to approximate the proposed model in terms of the time variable, and the Legendre spectral method is applied to discretize the fractional model with respect to the space variable. Also, the convergence analysis and stability of the proposed method are discussed and reviewed in this manuscript. In the end, some numerical examples are tested for the effectiveness and accuracy of the proposed method. As well as, in the numerical examples section, the presented numerical approach is compared with two numerical methods and the results are reported in a table. 2024 IOP Publishing Ltd. All rights, including for text and data mining, AI training, and similar technologies, are reserved. -
Evaluating the role of soil EPS in modifying the toxicity potential of the mixture of polystyrene nanoplastics and xenoestrogen, Bisphenol A (BPA) in Allium cepa L.
The coexistence of emerging pollutants like nanoplastics and xenoestrogen chemicals such as Bisphenol A (BPA) raises significant environmental concerns. While the individual impacts of BPA and polystyrene nanoplastics (PSNPs) on plants have been studied, their combined effects are not well understood. This study examines the interactions between eco-corona formation, physicochemical properties, and cyto-genotoxic effects of PSNPs and BPA on onion (Allium cepa) root tip cells. Eco-corona formation was induced by exposing BPA-PSNP mixtures to soil extracellular polymeric substances (EPS), and changes were analyzed using 3D-EEM, TEM, FTIR, hydrodynamic diameter, and contact angle measurements. Onion roots were treated with BPA (2.5, 5, and 10 mgL-1) combined with plain, aminated, and carboxylated PSNPs (100 mgL-1), with and without EPS interaction. Toxicity was assessed via cell viability, oxidative stress markers (superoxide radical, total ROS, hydroxyl radical), lipid peroxidation, SOD and catalase activity, mitotic index, and chromosomal abnormalities. BPA alone increased cytotoxic and genotoxic parameters in a dose-dependent manner. BPA with aminated PSNPs exhibited the highest toxicity among the pristine mixtures, revealing increased chromosomal abnormalities, oxidative stress, and cell mortality with rising BPA concentrations. In-silico experiments demonstrated the relationship between superoxide dismutase (SOD), catalase enzymes, PSNPs, BPA, and their mixtures. EPS adsorption notably reduced cyto-genotoxic effects, lipid peroxidation, and ROS levels, mitigating the toxicity of BPA-PSNP mixtures. 2024 Elsevier B.V. -
Extraction of Fungal Chitosan by Leveraging Pineapple Peel Substrate for Sustainable Biopolymer Production
The cost-effective production of commercially important biopolymers, such as chitosan, has gained momentum in recent decades owing to its versatile material properties. The seasonal variability in the availability of crustacean waste and fish waste, routinely used for chitosan extraction, has triggered a focus on fungal chitosan as a sustainable alternative. This study demonstrates a cost-effective strategy for cultivating an endophytic fungus isolated from Pichavaram mangrove soil in a pineapple peel-based medium for harvesting fungal biomass. Chitosan was extracted using alkali and acid treatment methods from various combinations of media. The highest chitosan yield (139 0.25 mg/L) was obtained from the pineapple peel waste-derived medium supplemented with peptone. The extracted polymer was characterized by FTIR, XRD, DSC, and TGA analysis. The antioxidant activity of the fungal chitosan was evaluated using DPPH assay and showed an IC50 value of 0.22 mg/L. Subsequently, a transparent chitosan film was fabricated using the extracted fungal chitosan, and its biodegradability was assessed using a soil burial test for 50 days. Biodegradation tests revealed that, after 50 days, a degradation rate of 28.92 0.75% (w/w) was recorded. Thus, this study emphasizes a cost-effective strategy for the production of biopolymers with significant antioxidant activity, which may have promising applications in food packaging if additional investigations are carried out in the future. 2024 by the authors. -
Exploring the Psychosocial Challenges and Strengths of Indigent Adolescents: A Reflexive Thematic Analysis of Counsellors Insights
Background: The Bronfenbrenner bioecological model of human development provides a comprehensive framework for understanding the complex interactions between individual factors and environmental influences on adolescent mental health, such as limited access to resources, exposure to violence and trauma, and parental neglect. While discussing the challenges faced by at-risk adolescents, it is important to focus on the strengths of resilient adolescents living in similar conditions. These individual differences are the precursors in determining their futures. Methods: The present study aimed to explore the psychosocial challenges and strengths of indigent adolescents. Eight counselors who had been working with indigent adolescents for at least three years in school or NGO settings were identified through a snowball sampling design and interviewed using a semi-structured interview schedule. Results: Reflexive thematic analysis of the interviews was done using Braun and Clarks protocol to identify themes. Challenges faced by indigent adolescents were a lack of parental supervision, vulnerability to cybercrime, emotional dysregulation, engagement in drug use, ambiguity in life aspirations and career goals, and societal mistrust and bias. The strengths identified were empathy, reconciliation dynamics and forgiveness, a yearning for change, a love of learning, help-seeking and help-providing behavior, attachment to religion and festivals, and a sense of gratitude and hopefulness, which indigent resilient adolescents display to navigate through their challenging lives. A detailed discussion of these challenges and strengths, along with their various dynamics, has also been provided. Conclusion: Identifying both the difficulties and strengths of indigent adolescents would promote more strength-based approaches to preventive and promotive mental health programs. 2024 The Author(s). -
Economic globalization and unemployment: Evidence from high-, middle- and low-income countries
This study intends to empirically evaluate the effects of economic globalization and its components (i.e. trade and financial openness) on unemployment in high-, middle- and low-income countries from 1991 to 2020. Further, it considers real GDP per capita (sectoral divisions of income, i.e. agriculture, industry and service sector) and urbanization as control variables in the unemployment function. On the empirical front, this study employs the Panel Dynamic Simulated ARDL model and the Kernel-Based Regularized Least Squares for long-run influence estimations. The emanating outcome of these analyses states that economic globalization destroys employment opportunities for low-income countries as it enhances unemployment in the long run. However, in high- and middle-income countries, economic globalization creates employment, which implies reducing unemployment in the long run. The result also indicates that trade and financial openness destroy employment opportunities in low-income countries. Although trade openness in middle-income countries shows the same effect, financial openness does not mimic the same. For high-income countries, trade openness reduces unemployment, but financial openness fosters it. Therefore, these findings indicate that to keep unemployment at a low level, policies related to the opening up of the economy in terms of factor mobility, offshoring, outsourcing and international trade need to be implemented in low-income countries. Moreover, a similar consideration is needed for high and middle-income countries to avoid faraway repercussions on unemployment due to becoming a peripheral country. 2024 John Wiley & Sons Ltd. -
Spectroscopic investigation on shuttlecock-shaped liquid crystalline trimers: Mesomorphic behaviour and its application in optical storage devices
In this paper, we discuss the synthesis and characterization of 2,3,4-tris[n-((4-(-cyanophenyl)diazenyl)phenoxy)alkyloxy]benzonitrile obtained by coupling 2,3,4-trihydroxy benzonitrile and (E)-4-((4-((n-bromoalkyl)oxy)phenyl)diazenyl)benzonitrile, pertain to shuttlecock shaped liquid crystals. The molecular structure was confirmed by NMR spectroscopic and elemental analyzer. The thermal behavior of the trimers was assessed using a polarizing optical microscope (POM) and differential scanning calorimetry (DSC). The three diazo groups in the trimers enabled us to study the photo-isomerization effect and evaluate their potential applications in optical storage devices. Importantly, we found these trimers easy to synthesize and process, paving the way for cost-effective alternatives to traditional LC materials. We fabricated an optical storage device to study the light effects on shuttlecock-shaped LC trimers, demonstrating that the geometry of the trimers plays a crucial role in determining structure-property relationships. 2024 -
Psychoneuroimmunological Perspective of Animal - Assisted Therapy
Animal-assisted therapy is a new and upcoming form of therapy that has shown multifarious benefits to participants. It is a goal-oriented therapeutic process with the incorporation of a qualified therapy animal in the therapeutic activities and conversations. This paper explores these benefits from a psychoneuroimmunological lens, wherein the interplay of and impact on an individual's psychological, neurological and immune systems are discussed. Positive physical interaction with therapy animals reduces undesirable symptoms and ailments such as stress, anxiety, depressive symptoms, aggressive tendencies, harmful behaviours, cardiovascular issues and unhealthy tendencies amongst others. It further promotes a healthier lifestyle, promoting quality of life, better heart health, cognitive functioning and overall well-being. The biological basis of these benefits is discussed. 2024 Oriental Scientific Publishing Company. All rights reserved. -
Humour as a Moderator Between Hassles and Well-Being
Humour is a universal phenomenon that offers several physiological and psychological benefits across cultures. The objectives of this study were to examine the relationships between daily hassles, humour and well-being; and to investigate the moderating effect of humour on the relationship between hassles and well-being. A correlational design was adopted to collect data from 644 participants (men = 300, women = 344), aged between 18 and 58years using purposive and snowballing sampling techniques. The Daily Hassles Scale, Sense of Humour Questionnaire (SHQ-R) and the Personal Well-Being IndexAdult (PWI-A) were administered to the sample. The self-report measures were appropriately scored and the collective data were analyzed. Statistical analyses revealed a positive relationship between sense of humour and well-being. A negative relationship was observed between sense of humour and hassles; and between well-being and hassles. Further, sense of humour was found to be moderating the relationship between daily hassles and well-being. This study highlights the role of humour in softening the impact of hassles on the well-being of the Indian population. This strengthens the construct of humour in the context of positive psychology. The Author(s) under exclusive licence to National Academy of Psychology (NAOP) India 2024. -
Synergistic advancements in energy storage: g-C3N4/NiFe2O4/PANI composite with augmented electrochemical capabilities
This study examines the electrochemical behaviour of a hybrid composite material of graphitic carbon nitride/Nickel ferrite/Polyaniline (g-C3N4/NiFe2O4/PANI) synthesized by hydrothermal method, coupled with in-situ polymerisation. The ensuing g-C3N4/NiFe2O4/PANI composite demonstrates superior characteristics for energy storage applications. Through a comprehensive analysis, we elucidate the combined effects of the distinct components, revealing improved electrochemical properties. The composite exhibits improved galvanostatic charge/discharge exhibiting a specific capacitance of 770 Fg?1 at 1 Ag?1 current density. This research underscores the perspective of the g-C3N4/NiFe2O4/PANI composite as a promising candidate for advanced energy storage systems. 2024 Elsevier Ltd -
Renewable Musa Sapientum derived porous nano spheres for efficient energy storage devices
Biomass-based carbonaceous materials derived from Musa Sapientum have gained much attention in recent years for their application in energy storage devices, especially supercapacitors. In the present work, we synthesized carbonaceous material from banana peel as the biomass precursor by using a pyrolysis method carried out at various temperatures (600, 800, and 1000 C). The characterization of the prepared carbonaceous materials BP600, BP800 and BP1000 was done by using different characterization techniques such as FTIR, XRD, FE-SEM, and TEM, studies. The electrochemical study of the synthesized material was carried out by cyclic voltammetry (CV), galvanostatic charge-discharge (GCD) electrochemical impedance spectroscopy (EIS). The supercapacitive performance of the material was studied using a 3-electrode system with 3M KOH as an electrolyte. As a result, the BP600 exhibited a better specific capacitance with higher energy and power densities along with a maximum cyclic stability of 16,000 cycles. To show the practical applicability of the material BP 600, two electrode system studies were carried out as well, which showed preferentially good values for specific capacitance with appreciable power and energy density values. The study provides us with a green approach for the fabrication of non-toxic, low-cost, and environmentally friendly potential porous carbonaceous electrode materials by converting bio-waste into a clean and renewable source of energy. 2024 The Author(s). Published by IOP Publishing Ltd. -
Technology acceptance model and customer engagement: mediating role of customer satisfaction
The primary aim of this study is to examine the influence of the technological acceptance model on customer engagement. An additional aim of this study is to examine the mediating effect of customer satisfaction in the relationship between the technology acceptance model and customer engagement. The present study gathered primary data from users of retail banking services in specific metropolitan areas in India. The participants were chosen based on their considerable expertise in utilizing online, digital, and mobile banking platforms and their substantial knowledge of implementing advanced e-banking strategies. The application of confirmatory factor analysis investigated measurement validity. The studys findings indicate a significant correlation between emotional and rationalengagement, mediated via perceived usefulness. Additionally, the study revealed that the relationship between perceived usefulness and emotional engagementis mediated by customer satisfaction. Furthermore, it can be observed that this factor entirely mediates the relationship between transaction cost and emotional engagement. The studys findings suggest that customer satisfaction is a complete mediator in the association between transaction cost and rational engagement. The results of this study make a valuable contribution to the current body of literature on the technological acceptance model, customer satisfaction, and customer engagement. The Author(s), under exclusive licence to Springer Nature Limited 2023.