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Nanomaterials for A431 Epidermoid Carcinoma Treatment
Malignancy is the ancient sickness that causes an increased rate of mortality worldwide. Traditional malignant growth treatments that are clinically utilized comprise chemotherapy, radiotherapy, and medical procedure. Despite the fact that there have been motivating enhancements in the nanotechnology and biomedical field, malignant growth remains the most urgent condition to treat, as the central reason for mortality. Nanotechnology has the possibility to improve medication transport and delivery by modifying pharmacokinetics and conveyance, resulting in reduced negative reactions and in this manner improving precision. Some issues exist regarding destinations and the difficulties that occur, and the potential for success becomes closer with every discovery. Nanomaterials are smaller in size than organic macromolecules. More correctly, they as a rule have a width of many nanometers (nm), which makes them from 100 up to multiple times smaller than even one malignancy cell. Nanoparticles can occur in sizes running from 10 up to 400nm, and can likewise be used with a simple set up or a blend of pharmacologically dynamic medications, depending on a superficial level of properties. The various aspect of nanotechnology for malignant growth treatment include exact targeting of the lively segments in cell/tissues, producing upgrades responsive medication discharge, defeating natural obstructions, interfacing against disease dynamic system with imaging atoms, improving disease examination, and imaging. For the most part, nanoparticles burdened with mending operators are conveyed experimentally for firm malignancy treatment. Todays nanotechnology is a magnificent platform for the treatment of differing malignant growths. 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG. -
Nanomaterials-Based Chemical Sensing
Nanotechnology is an achievement in the modern period because of its adaptable properties as per its size alterations. Nanomaterials with their size ranging from 1 to 100nm hold incredible novel properties and functionalities because of their molecular arrangements in nano-scale. Nanotechnologies add to pretty much every field of science, including material science, materials chemistry, physics, biology, software and computational engineering and so on. Lately, nanotechnology has been applied to different fields with promising outcomes, particularly in the field of detecting and remediation of toxicity levels, imperilling the ecological solidness just as it does to human wellbeing. One of the principal research interests using nanomaterials is detecting poisonous heavy metal ions. Carbon-based nanomaterials, which are remarkable in view of their toxic-free nature, high surface area and biocompatibility, are valuable for ecological treatments. Heavy metal pollution of water resources is a major issue that poses danger to health and wellbeing. Carbon-based nanomaterials have incredible potential for the detection as well as treatment of heavy metals from water sources in light of their large surface area, nano-scale and accessibility towards various functionalities as they are simpler to be chemically altered and hence reused. Apart from the conventional gas sensors based on SnO2, Fe2O3, In2O3 etc., gas sensors based on nanocarbons materials like carbon nanotubes (CNTs), nanosheets of graphene, carbon nano-fibres etc. exhibit high efficacy when it comes to gas-sensing strategy. Likewise, nanocarbon with hybrids of noble metals or semiconducting oxides can lead to a better performance considering gas-sensing applications. Here in this review, we describe the progress of carbon-based nanomaterials in toxicity detection and remediation. In addition to that, recent trends in nanomaterials-based sensing revealed the advancement of gas sensors based on nanocarbons. 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. -
Nanomedicine: Insight analysis of emerging biomedical research and developments
The field of nanomedicine has undergone a revolution owing to the specific optical, electrical, and mechanical behaviors of nanomaterials that are extensively utilized for the detection of biomolecules, improved therapeutics, and imaging of diseased tissues. Different cells have their own unique markers which can be detected by specific nanomaterials which in turn can be used to target micro levels of medicine in precision medicine. Most of the advances in nanomedicine will have effects on the healthcare delivery systems. More works have focused on screening procedures that have better sensitivity and specificity for disease detection, which in turn will greatly improve diagnostic and prognostic domains, thereby reducing healthcare costs. Nanomedicine has the advantages of facilitating early disease detection, quantification of tumor cells and toxicmolecules, delivery of drugs to specific cells like the tumor cells etc. This chapter deals with research and development in nanomedicine which has been a top priority in most of the developed countries, with a view to optimize factors like dose response, efficacy, targeting ability, safety and bioavailability. The Author(s), under exclusive license to Springer Nature Switzerland AG 2023. All rights reserved. -
Nanoparticle aggregation effects on radiative heat transport of nanoliquid over a vertical cylinder with sensitivity analysis
A sensitivity analysis is performed to analyze the effects of the nanoparticle (NP) aggregation and thermal radiation on heat transport of the nanoliquids (titania based on ethylene glycol) over a vertical cylinder. The optimization of heat transfer rate and friction factor is performed for NP volume fraction (1% ? ? ? 3%), radiation parameter (1 ? Rt ? 3), and mixed convection parameter (1.5 ? ? ? 2.5) via the face-centered central composite design (CCD) and the response surface methodology (RSM). The modified Krieger and Dougherty model (MKDM) for dynamic viscosity and the Bruggeman model (BM) for thermal conductivity are utilized to simulate nanoliquids with the NP aggregation aspect. The complicated nonlinear problem is treated numerically. It is found that the temperature of nanoliquid is enhanced due to the aggregation of NPs. The friction factor is more sensitive to the volume fraction of NPs than the thermal radiation and the mixed convection parameter. Furthermore, the heat transport rate is more sensitive to the effect of radiative heat compared with the NP volume fraction and mixed convection parameter. 2021, Shanghai University and Springer-Verlag GmbH Germany, part of Springer Nature. -
Nanoparticle aggregation kinematics on the quadratic convective magnetohydrodynamic flow of nanomaterial past an inclined flat plate with sensitivity analysis
The study focuses on the aggregation kinematics in the quadratic convective magneto-hydrodynamics of ethylene glycol-titania ((Formula presented.)) nanofluid flowing through an inclined flat plate. The modified Krieger-Dougherty and Maxwell-Bruggeman models are used for the effective viscosity and thermal conductivity to account for the aggregation aspect. The effects of an exponential space-dependent heat source and thermal radiation are incorporated. The impact of pertinent parameters on the heat transfer coefficient is explored by using the Response Surface Methodology and Sensitivity Analysis. The effects of several parameters on the skin friction and heat transfer coefficient at the plate are displayed via surface graphs. The velocity and thermal profiles are compared for two physical scenarios: flow over a vertical plate and flow over an inclined plate. The nonlinear problem is solved using the RungeKutta-based shooting technique. It was found that the velocity profile significantly decreased as the inclination of the plate increased on the other hand the temperature profile improved. The heat transfer coefficient decreased due to the increase in the Hartmann number. The exponential heat source has a decreasing effect on the heat flux and the angle of inclination is more sensitive to the heat transfer coefficient than other variables. Further, when radiation is incremented, the sensitivity of the heat flux toward the inclination angle augments at the rate 0.5094% and the sensitivity toward the exponential heat source augments at the rate 0.0925%. In addition, 41.1388% decrement in wall shear stress is observed when the plate inclination is incremented from (Formula presented.) to (Formula presented.). IMechE 2021. -
Nanoparticles and convergence of artificial intelligence for targeted drug delivery for cancer therapy: Current progress and challenges
Cancer is a life-threatening disease, resulting in nearly 10 million deaths worldwide. There are various causes of cancer, and the prognostic information varies in each patient because of unique molecular signatures in the human body. However, genetic heterogeneity occurs due to different cancer types and changes in the neoplasms, which complicates the diagnosis and treatment. Targeted drug delivery is considered a pivotal contributor to precision medicine for cancer treatments as this method helps deliver medication to patients by systematically increasing the drug concentration on the targeted body parts. In such cases, nanoparticle-mediated drug delivery and the integration of artificial intelligence (AI) can help bridge the gap and enhance localized drug delivery systems capable of biomarker sensing. Diagnostic assays using nanoparticles (NPs) enable biomarker identification by accumulating in the specific cancer sites and ensuring accurate drug delivery planning. Integrating NPs for cancer targeting and AI can help devise sophisticated systems that further classify cancer types and understand complex disease patterns. Advanced AI algorithms can also help in biomarker detection, predicting different NP interactions of the targeted drug, and evaluating drug efficacy. Considering the advantages of the convergence of NPs and AI for targeted drug delivery, there has been significantly limited research focusing on the specific research theme, with most of the research being proposed on AI and drug discovery. Thus, the study's primary objective is to highlight the recent advances in drug delivery using NPs, and their impact on personalized treatment plans for cancer patients. In addition, a focal point of the study is also to highlight how integrating AI, and NPs can help address some of the existing challenges in drug delivery by conducting a collective survey. 2023 Das and J. -
Nanoparticles as fillers in composites for x-ray and gamma-ray shielding: A review
In last few decades, nanomaterials have gained enormous attention in the scientific industry due to their tunable physico-chemical and biological properties with enhanced performance over their bulk counterparts. In particular, nanoparticles have been extensively investigated for their usefulness in X-ray and gamma-ray shielding applications. Various elements and compounds, with high atomic numbers and effective atomic numbers respectively, have the potential to form nanoparticles that offer remarkable enhancement in the shielding performance. Composites, obtained by doping different nanoparticles into structural matrices (concrete, glass, or polymers), not only possess striking thermo-mechanical properties but also are effective shielding materials to replace conventional lead shields. This review is an attempt to throw light on various aspects of nanoparticles and their influence on shielding effectiveness. The authors also summarize the experimental findings so as to highlight the potential underlying the radiation-matter interaction mechanism in nanostructured systems. Copyright 2023, IGI Global. -
Nanosheets of nickel, cobalt and manganese triple hydroxides/oxyhydroxides as efficient electrode materials for asymmetrical supercapacitors
Transition metals play a significant role in energy storage applications mainly as electrode materials in supercapacitors. In this work, triple hydroxide/oxyhydroxide nanosheets of a nickel, cobalt and manganese (NCM) composite were electrochemically deposited on carbon cloth (CC) and used as electrode materials in supercapacitors. In a three electrode system the composite delivered a specific capacitance of 707 F g -1 at a current density of 3 A g -1 which retained its stability even at a higher current density of 50 A g -1 . An asymmetric supercapacitor (ASC) was assembled and characterized using NCM as the positive electrode, activated carbon as the negative electrode and Whatman filter paper soaked in KOH as the separator. The device operated in a working potential window of 1.75 V and it delivered a power density of 13.12 kW kg -1 and an energy density of 23.7 W h kg -1 . 2019 The Royal Society of Chemistry. -
Nanostructured ZnCo2S4@metal organic frameworks composite for supercapacitor by ultrasonication supported hydrothermal reaction
Electrode materials for supercapacitors, sensors, and battery applications were frequently manufactured using the chemistry of metal organic framework nanostructured materials. These materials have three-dimensional networks between organic linkers and metal precursors thanks to diverse chemical alterations. Due to their enhanced surface characteristics, porous nature, and strong connecting organic molecules for numerous possible applications, MOFs have a wide range of uses. In this study, we used a sonicated enhanced hydrothermal reaction to fabricate ZnCo2S4 and ZnCo2S4 on the metal organic framework composite materials. Raman, FTIR, XRD, XPS, SEM, and SEM-EDS tests were utilized to confirm the composite's structural and morphological features. With 1 M KOH electrolyte, composite electrodes for supercapacitor fabrication were produced. The composite electrodes have a stability under cycles count of 5000 and a capacitance of 550 F/g at a density of 1 A/g. 2024 Elsevier B.V. -
Nanotechnological approach in nutraceuticals
Nanonutraceuticals are a fabrication process for extending the food quality and shelf life using nanocomposites for the protection of nutrition supplements in food, which acts as encapsulation against the factors causing spoilage. This chapter discusses the advantages of nanotechnology in food processing, packaging, and post packaging. The use of nanomaterials as ingredients, packaging materials, and for processing packed food imparts better taste, texture, and consistency. Nanotechnology improves the flavor, taste, and has better delivery of culinary balance. Encapsulation in food packaging helps maintain the taste and odor by maintaining the permeability of packaging, food texture, and the matrix, while regulating the specific release of active agents at a specific rate and time. Thus, a nanopackaging delivery system helps maintain the moisture and temperature. The impact of the use of nanomaterials should be studied under various circumstances to help understand nanomaterial use to deliver bioactive compounds. 2024 John Wiley & Sons, Inc. All rights reserved. -
Nanovaccinology and superbugs
Superbugs pose a serious threat to humans as many of the currently available antibiotics are not effective in treating the diseases inflicted by these microbes.Among the different bacteria causing clinical infections, Klebsiella pneumoniae, Escherichia coli, Serratia marcescens, Pseudomonas aeruginosa, Staphylococcusaureus, Proteus mirabilis, and so on, are some of the most vicious ones emergingat an unprecedented rate with huge impact on public health. In this context, prophylacticmeasures for these diseases assume great significance and NVs indeedfit in as a promising measure. Sustained release, improved antigen stability, betterimmunogenicity, better access to lymph nodes and low minimum immunotoxicitytranslates to the better efficacy of nano-based vaccines. Lipid-based NP (nanoparticles),dendrimers, Polymeric NP, self-assembled peptide NP, virus like particles(VLPs), and so on, are the promising NV (nanovaccines) delivery approaches.Improvisations of NVs by decorating NP surfaces with ligands that target specificimmune cells like the dendritic cells is also a promising approach to induce both Tand B cell responses. The current review focuses on the breakthroughs in the NVdomain with the challenges and opportunities of creating NVs to curb the menaceof superbugs. 2022 Scrivener Publishing LLC. All rights reserved. -
Narrating 'Devdas' through cinema: A study on characterization and power relations /
Sarat Chandra Chattopadhyay’s Bengali romance novel ‘Devdas’ has been adapted into movies for over eight decades, four of which are in Hindi. Many directors have applied their own creativity in order to bring out and present a different Devdas every time they remake the film. This paper tries to analyze the way the movies have changed over the years in relation to the change in characterization and power relations, with narration weaving these parameters together. -
Narrating the City: Calcutta in Raj Kamal Jha???s If You Are Afraid of Heights and The Blue Bedspread
The portrayal of the city in literature is not a recent phenomenon. The city in literature has a history as old as the history of the city itself. This thesis titled ???Narrating the City: Calcutta in Raj Kamal Jha???s If You are Afraid of Heights and The Blue Bedspread??? is an attempt to understand how the city of Calcutta is portrayed in these two novels and how the city affects the people and vice versa. Every narration happens within the coordinates of time and space. Narrative is the representation of movement within the coordinates of time and space. Literary narrative is the literary or semiotic representation of movement within the coordinates of time and space. In the same manner narrating the city is the literary representation of the movement of the city and things in the city both living and non-living within the coordinates of time and space. The introductory chapter places the study in the context analysing the representation of the city in literature. The definition of key concepts and a literature review are done in order to understand the narrative, city and above all the narrating of the city in literature. The second chapter titled ???Calcutta in The Blue Bedspread???, shows how the city of Calcutta is portrayed in the novel The Blue Bedspread. This chapter is divided into different subsections according to the different themes identified. The third chapter titled ???Calcutta in If You are Afraid of Heights??? shows how the city of Calcutta is portrayed in the novel If You are Afraid of Heights. The fourth and the final chapter details the general conclusions derived from the study. Calcutta is narrated differently through these two novels. The Blue Bedspread presents a city of Calcutta which is more of a realistic nature. There is an over emphasis given to the description of the places as the novel is stacked with references to the buildings and places in the city. Thus it becomes a story of the city than the story of a specific person (character) or persons viii (characters). There is a close connection between the city and the people and vice versa. The names of the characters are not mentioned in the novel and this anonymity of the main characters points to the fact that this is a novel about anybody who is influenced by the city, in this case the city of Calcutta. If You are Afraid of Heights is a magic realist portrayal of the city of Calcutta. The characters of the city oscillate between reality and fantasy. This novel is not stacked with references to the places or spaces in the city, even though there are some references to them. The Blue Bedspread is the story of the city being projected through the realistic places and on the other hand If You are Afraid of Heights is the story of the city being projected through the magic realist presentation of the places, spaces and time in the city. -
Narrating Trauma as Victims of Human Trafficking in China: A Study on Select North Korean Memoirs
The memoirs titled In Order to Live; A North Korean Girl's Journey, to Freedom and; A Thousand Miles to Freedom: My Escape from North Korea are written by Yeonmi Park and Eunsun Kim two women who managed to escape from North Korea. They went through an experience of being forced into labour in China as victims of trafficking. In their memoirs these authors vividly depict the pain that comes with being exploited. The main aim of this study is to analyse how memoirs can effectively address the issue of trafficking. These remarkable women skilfully use the memoir genre to make a personal plea for action. They strategically make choices appeal to readers emotions openly share their distressing experiences and support their stories with research and evidence that connect their experiences with the broader problem of human trafficking in China. This study clearly shows that both these memoirs emphasize the importance of the memoir genre in advocating for rights. It also highlights how survivor memoirs have the potential to inspire advocacy and involvement, in combating trafficking. 2025 Sciedu Press. All rights reserved. -
Narration of Self in the Autobiographies of Augustine of Hippo and Teresa of Avila
This dissertation is a study of narration of self in the autobiographies of Augustine of Hippo and Teresa of Avila. Confessions, the autobiography of Augustine of Hippo, is considered the first organized spiritual autobiography in the Western Europe and The Life of Teresa of Jesus measured as the first spiritual autobiography among women. In the main argument I propose that the self narrated in Confessions is a confessional self and the self narrated in The Life of Teresa of Jesus is an inquisitional self. According to Christian tradition confession is the disclosure of sins to a priest and acknowledging and praising the Holiness of God for his mercy towards a sinful man. In Confessions, Augustine makes a confession to God, to himself, and to the human kind. Augustine narrates a confessional self because all throughout the text we observe a total surrendering of his sins and flaws to God without any justification or argument similar to a confession. The self narrated by Teresa in The Life of Teresa of Jesus, I argue, is an inquisitional self. It is because Teresa has written the autobiography by the command of her confessors. Teresas vision and spiritual ecstasies made a contradiction in the church and predicted that it was from devil. In order to prove the reality and truth it was necessary to submit her life history to the judicial court, which was established as an inquisitional court. Therefore her confessors asked her to write her life story only with the explanation of spiritual favours she received. She was forced to write a life story with many restrictions. Consequently the self narrated in The Life of Teresa of Jesus became an inquisitional self where she hides many incidents of the real life. -
Narrative Therapy with Dalit Female Survivors of Violence
Narrative therapy is an evidence-based therapeutic intervention that can help address trauma experienced by women who have experienced violence. Narrative therapists open up new perspectives for their clients by examining moments of strength, vitality, and autonomy, which are often hidden in stories about oppression, suffering, and marginalization. Dalit women who participated in the research revealed how the stories opened up new possibilities for constructing unique narratives. A multiple case study design was used to elicit the responses of female survivors with severe mental illness to physical, sexual, and psychological abuse perpetrated by Dalit and higher caste men. 2024 Mary Ann Liebert Inc.. All rights reserved. -
Narratives of the self: Comments and confessions on Facebook
Narratives are structured around events, which are used to tell a story. The self is perpetually being constructed through narratives of experience. This chapter focuses on the phenomenon of Facebook confession pages and how they contribute to the construction of digital identity. Drawing on insights from my project on the role of Facebook College Confession pages, the chapter examines how these platforms have transformed the way users express and shape their identities. The anonymity provided by these pages allows users to post confessions without revealing their identities, encouraging a form of virtual self-exploration. These confessions, often written by nameless authors, generate a complex and ongoing narrative of identity, shaped by the interaction of multiple voices and viewpoints. The chapter also explores the motivations behind sharing personal confessions, even when the responses may be negative, and how this contributes to the perpetual construction of the digital self. By examining the intersection of public and private spheres in these online spaces, this chapter highlights how the breaking of the public-private divide enables users to create and negotiate their identities in a digital, networked world. The narrative constructed is endless, and the post is not an end in itself. It paves the way for the generation of an endless narrative by multiple authors with multiple viewpoints. This chapter explores the reasons behind sharing such posts on Facebook, even if the comments are negative in tone. It will refer to Anthony Giddens' concept of time-space "distanciation" (Keefer et al., 2019) to show how multiple tellers through their narratives help to build the complex networked identity of a user. The study will also analyse the role played by the breaking of the public-private divide in creating such spaces for the construction of a private self through public voices. 2024 Rimi Nandy. -
Narratives on using critical approaches in teacher education
Using the approach of autoethnographic narrative, three teacher educators from a cosmopolitan city in South India discuss how they use critical approaches in preparing preservice teachers and educational psychologists in the courses that they teach at a private university. The students are sensitized about the marginalized and the privileged sections in a multicultural and multilingual nation as India and to become culturally responsive in their classrooms or with their clientele in terms of their dispositions, knowledge, and skills. The chapter also describes the integration of critical approaches in the doctoral program aimed at addressing educational disparities and promoting social justice in education. 2024, IGI Global. All rights reserved. -
Narrativity and the Problematics of Authenticity in Hungry Ghosts by Kevin Jared Hosein
Postcolonial historical fictions, set in turbulent times, grapple with the question of authenticity in their fictional representations of events and individuals of the past. Trinidadian novelist Kevin Jared Hoseins Hungry Ghosts (2023), set in the estate barracks and surrounding milieu of 1940s Trinidad, is no exception. The paper argues for a nuanced understanding of the term authenticity in our reading of historical fictions, and explores Hoseins use of the formal, imaginative and affective dimensions of narration in negotiating representational adequacy and strengthening the significant thematic concerns in the text. Through textual analysis, the paper explores how Hosein situates his text firmly within the spatio-temporal reality of the period and captures the struggles of becoming confronting a population whose lives are coloured by historical trauma and continuing spatial hierarchy. 2024 The Editorial Board, Current Writing. -
Narrowband and Wideband Directional Beamformer with Reduced Side Lobe Level
In this paper, the synthesis of narrow and wideband beamformers with reduced side lobe level and wide beam steering capability is presented. A closed form expression with slope equalization technique is derived for array factor of the beamformer to meet the desired beam-pattern specifications of Half Power Beam-Width (HPBW)and Side Lobe Level (SLL). The proposed beamformer design is adaptable to any bandwidth and null placement in the desired direction. The slope equalization method improves the SLL of the beamformer. Compared to Kaiser, Chebyshev, DPSS and Taylor beamformers, the proposed narrowband and wideband beamformers exhibit lower and tapered side lobes, hence improved First Null to Last Null (FNLN)ratio. The proposed wideband beamformer exhibits superior performance in the wideband frequency range of 1-3GHz. 2019 IEEE.