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Monoclonal antibodies targeting the Erns protein of classical swine fever virus: application for virus detection
Classical swine fever (CSF), caused by the classical swine fever virus (CSFV; genus Pestivirus), is a highly transmissible disease in pigs that leads to severe economic losses for pig farmers worldwide. Early and accurate diagnosis of CSFV infections is crucial for effective containment of the disease, especially in endemic areas. In this study, the full-length viral protein Erns was successfully expressed in E. coli. The recombinant protein was purified using Ni-NTA affinity chromatography, and its antigenicity confirmed by western blot and indirect ELISA (iELISA) using CSFV-specific antiserum. The purified Erns protein was then used as an immunogen to generate murine hybridomas producing monoclonal antibodies (mAbs). A panel of 15 mAbs targeting this protein was characterized using iELISA and western blotting, for their ability to react with native antigens in cultures infected with CSFV. These mAbs have the potential to be used in the development of diagnostic tools, particularly for the detection and titration of virus-infected cultures through endpoint dilution assays. 2025 Elsevier B.V. -
Interplay of financial inclusion and economic growth in emerging economies
This study delves into the complex link between financial inclusionboth traditional and digitaland economic growth across emerging economies from 1990 to 2022, using Dynamic Simulated ARDL and Driscoll-Kraay Standard Error techniques. Key findings highlight that traditional financial inclusion correlates positively with economic growth, whereas digital financial inclusion presents obstacles. Additionally, fiscal, monetary, and trade policies play vital roles: fiscal policies in Brazil, Colombia, and Mexico focus on infrastructure, social programs, and tax reforms, respectively, to spur growth. Monetary policies include Brazil's inflation targeting, Turkey's interest rate adjustments, and India's MUDRA scheme, which promotes entrepreneurship. Trade policies, such as Chile's Free Trade Agreements and Mexico's participation in NAFTA, improve market access and economic resilience, while Egypt and Saudi Arabia focus on foreign direct investment and economic diversification. The study emphasizes coordinated policy efforts for sustained growth, advocating for financial inclusion supported by robust regulations and government investments in critical areas like infrastructure and healthcare. Central banks contribute by maintaining price stability and credit access, while strategic trade agreements and export diversification enhance economic resilience. The focus of the study on emerging economies and macro-level insights calls for further research at the micro-level to refine these results. By maintaining policy coherence and regular evaluations, these strategies aim to foster inclusive, long-term economic growth. 2025 The Author(s) -
Lived experiences of urban working mothers during pandemic: A matricentric exploration in the Indian context
In India, entrenched patriarchal norms dictate gender roles, perpetuating men-headed families and patrilineal traditions deeply ingrained in its culture. Within this framework, working mothers daily confront gender biases despite society undervaluing their crucial roles in caregiving and the economy. The Covid-19 pandemic intensified these challenges, as working mothers faced heightened expectations to excel in both professional and maternal roles. With inadequate support and intensified caregiving demands, their physical and mental well-being significantly suffered. This article explores the complex realities experienced by Indian working mothers during the pandemic. Viewing motherhood through a matricentric lens underscores its importance to society while highlighting the need to redistribute caregiving responsibilities beyond mothers alone. The researchers conducted a qualitative study, interviewing 30 Indian working mothers from various professional backgrounds using semi-structured interviews. Thematic analysis revealed that despite seventy-seven years of independence, mothers in India continue to grapple with patriarchal oppression, inequality, and violence, underscoring the persistent challenges faced in navigating societal norms and expectations. By gaining insight into their experiences, policymakers can better grasp these burdens and implement measures to address associated physical and mental health concerns. 2025 Elsevier Ltd -
Thermosensitive In-situ gel based on halloysite nanotube/chitosan for site-specific delivery of aceclofenac
Periodontitis, a severe and chronic inflammatory gum disease, necessitates the development of advanced drug delivery strategies due to the limitations of conventional therapies, such as rapid drug clearance and inadequate site-specific retention. This study addresses these challenges by formulating and evaluating a novel aceclofenac-loaded halloysite nanotube (HNT) In-situ gel designed for effective local treatment of periodontitis. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID) known for its potent anti-inflammatory action and reduced gastrointestinal side effects, was encapsulated within HNTs to achieve sustained drug release and enhanced therapeutic efficacy. These drug-loaded HNTs were subsequently incorporated into a thermosensitive In-situ gelling system composed of medium molecular weight chitosan, sodium bicarbonate, and sodium ?-glycerophosphate. This gel formulation demonstrated favourable properties, including syringeability, swelling capacity, and temperature-responsive gelation at physiological conditions. The comprehensive characterization techniques such as FTIR, SEM, TEM, PXRD, DSC/TGA, confirmed successful drug encapsulation, structural stability, and uniform distribution within the gel matrix. The in vitro release studies revealed a sustained drug release profile, following zero-order and KorsmeyerPeppas kinetics, indicative of a Super Case-II transport mechanism. This novel, thermoresponsive local drug delivery system shows strong potential to improve the clinical management of periodontitis by providing prolonged therapeutic action, targeted delivery, and improved patient compliance. 2026 American Pharmacists Association. -
Internet chat based intervention as a mode for therapy and counselling
Increasing mental health issues in India demands for a strong intervention to curb the rise. According to the World Health Organization, roughly around 21 Indians out of 100,000 die by suicide every year. The burden on mental health domain increases due to the existing system as most of the existing services follow a traditional approach and are most sought after but lack reachability and ease of access. This study recognises the need for programmes that help in reachability and ease of access while simultaneously maintaining anonymity, therefore, analyses the impact of chat-based therapy provided online through the platform. The paper analyses the difference in subjective unit of well-being (SUW) pre and post chat-based sessions among 2624 college students and 805 corporate employees. The Wilcoxon signed rank test between pre and post intervention indicates significant results with the p < 0.001 (Z = -44.100a) suggesting and increase in SUW scores post intervention. Further, the Kruskal-Wallis test revealed that the gender of the clients has an association with the SUW scores (p < 0.05). It was also found that the duration of the sessions had a positive relation with the impact scores (p < 0.001). The Author(s), 2025. -
A bibliometric analysis of scientific literature on adverse childhood experiences (2004-2024)
Adverse childhood experiences (ACE) significantly impact physical, mental and social well-being, making them a critical area of research. This study analyzed the emerging trends and intellectual structure of ACE research and identified key contributors, including the most productive nations, journals and authors. Using bibliometric tools and VOSviewer software (version 1.6.20), 1,957 articles from the Scopus database (2004 to March 2024) were systematically analyzed. A notable finding was the surge in ACE-related publications during the COVID-19 pandemic, potentially reflecting increased global attention on childhood adversity amid heightened social and economic challenges. The analysis also revealed a striking dearth of studies from the Global South, with the field predominantly shaped by Western nations, like the United States, the United Kingdom, Australia and Canada. Leading journals, such as the Journal of Interpersonal Violence, and prolific authors, like Kevin T. Wolff, played a central role in advancing the field. Co-citation analysis uncovered four thematic clusters: (1) conceptualization and assessment of ACE, (2) health implications, (3) mental health impacts and (4) juvenile delinquency. These clusters, though distinct, showed significant thematic overlaps, reflecting the interconnected nature of ACE research and its intellectual structure. These findings underscore the need for more regionally diverse and interdisciplinary approaches to understanding global childhood adversity. The Author(s), 2025. -
Serendipitous detection of an intense X-ray flare in the weak-line T Tauri star KM Ori with SRG/eROSITA
Weak-line T Tauri stars (WTTS) exhibit X-ray flares, likely resulting from magnetic reconnection that heats the stellar plasma to very high temperatures. These flares are difficult to identify through targeted observations. Here, we report the serendipitous detection of the brightest X-ray flaring state of the WTTS KM Ori in the eROSITA DR1 survey. Observations from SRG/eROSITA, Chandra X-ray Observatory, and XMM-Newton are analysed to assess the X-ray properties of KM Ori, thereby establishing its flaring state at the eROSITA epoch. The long-term (1999-2020) X-ray light curve generated for the Chandra observations confirmed that eROSITA captured the source at its highest X-ray flaring state recorded to date. Multi-instrument observations support the X-ray flaring state of the source, with time-averaged X-ray luminosity reaching at the eROSITA epoch, marking it the brightest and possibly the longest flare observed so far. Such intense X-ray flares have been detected only in a few WTTS. The X-ray spectral analysis unveils the presence of multiple thermal plasma components at all epochs. The notably high luminosity , energy (erg), and the elevated emission measures of the thermal components in the eROSITA epoch indicate a superflare/megaflare state of KM Ori. Additionally, the H line equivalent width of from our optical spectral analysis, combined with the lack of infrared excess in the spectral energy distribution, were used to re-confirm the WTTS (thin disc/disc-less) classification of the source. The long-duration flare of KM Ori observed by eROSITA indicates the possibility of a slow-rise top-flat flare. The detection demonstrates the potential of eROSITA to uncover such rare, transient events, thereby providing new insights into the X-ray activity of WTTS. The Author(s), 2025. Published by Cambridge University Press on behalf of Astronomical Society of Australia. -
The Indian Pulsar Timing Array data release 2: I. Dataset and timing analysis
The Indian Pulsar Timing Array (InPTA) employs unique features of the upgraded Giant Metrewave Radio Telescope (uGMRT) to monitor dozens of the International Pulsar Timing Array (IPTA) millisecond pulsars (MSPs), simultaneously in the 300500 MHz and the 12601460 MHz bands. This dual-band approach ensures that any frequency-dependent delays are accurately characterised, significantly improving the timing precision for pulsar observations, which is crucial for pulsar timing arrays. We present details of InPTAs second data release that involves 7 yr of data on 27 IPTA MSPs. This includes sub-banded times of arrival (ToAs), dispersion measures (DM), and initial timing ephemerides for our MSPs. A part of this dataset, originally released in InPTAs first data release, is being incorporated into IPTAs third data release, which is expected to detect and characterise nanohertz gravitational waves (GWs) in the coming years. The entire dataset is reprocessed in this second data release providing some of the highest precision DM estimates so far and interesting solar wind-related DM variations in some pulsars. This is likely to characterise the noise introduced by the dynamic inter-stellar ionised medium much better than the previous release thereby increasing sensitivity to any future GW search. The Author(s), 2025. Published by Cambridge University Press on behalf of Astronomical Society of Australia. -
Probing the resolved K-S relation in nearby galaxies: Insights from UVIT and ALMA observations
This study examines the resolved Kennicutt-Schmidt (rK-S) relation, defined as the connection between the star formation rate surface density (?SFR) and the molecular gas mass surface density (?H2) in the high-density central regions of three nearby barred spiral galaxies hosting AGN: NGC 1365, NGC 1433, and NGC 1566. Utilising high-resolution archival data from AstroSat/UVIT for UV imaging and Atacama Large Millimetere/submillimetre Array (ALMA) for CO(2-1) molecular gas mapping, we explore recent star formation and gas distribution with a spatial resolution of ?120132 pc. Our findings reveal a sublinear rK-S law, with slopes ranging from ?0.17 to ?0.71. Notably, NGC 1566 exhibits a robust rK-S relation consistent with previous studies, while NGC 1365 and NGC 1433 exhibit weaker correlations. These differences are likely due to the smaller number of identified star-forming regions in these galaxies compared to NGC 1566, as well as the central molecular gas concentrations and varying star formation activity in their bars and nuclear regions. These results also support the idea that the rK-S relation deviates from linearity in extreme environments, such as starburst galaxies and galactic centres. Additionally, we find a generally low median star formation efficiency (SFE) within the bars of these galaxies, suggesting that while bars may drive nuclear starbursts and contribute to bulge growth, they do not significantly increase SFE. Furthermore, a negative correlation between SFE and ?H2 is observed across the sample, both within and outside the bar regions, suggesting that higher ?H2 may lead to lower SFE in the central regions of these galaxies. Our findings highlight that ?H2 plays a primary role in shaping the observed trends in SFE, rather than the presence of a bar itself. The Author(s), 2025. Published by Cambridge University Press on behalf of Astronomical Society of Australia The Author(s) -
Connecting the dots: Tracing the evolutionary pathway of polar ring galaxies in the cases of NGC 3718, NGC 2685, and NGC 4262
Polar ring galaxies (PRGs) are a unique class of galaxies characterised by a ring of gas and stars orbiting nearly orthogonal to the main body. This study delves into the evolutionary trajectory of PRGs using the exemplary trio of NGC 3718, NGC 2685, and NGC 4262. We investigate the distinct features of PRGs by analysing their ring and host components to reveal their unique characteristics through spectral energy distribution (SED) fitting. Using CIGALE, we performed SED fitting to independently analyse the ring and host spatially resolved regions, marking the first decomposed SED analysis for PRGs, which examines stellar populations using high-resolution observations from AstroSat UVIT at a resolved scale. The UV-optical surface profiles provide an initial idea that distinct patterns in the galaxies, with differences in FUV and NUV, suggest three distinct stages of ring evolution in the selected galaxies. The study of resolved-scale stellar regions reveals that the ring regions are generally younger than their host galaxies, with the age disparity progressively decreasing along the evolutionary sequence from NGC 3718 to NGC 4262. Star formation rates (SFR) also exhibit a consistent pattern, with higher SFR in the ring of NGC 3718 compared to the others, and a progressive decrease through NGC 2685 and NGC 4262. Finally, the representation of the galaxies in the HI gas fraction versus the NUV- plane supports the idea that they are in three different evolutionary stages of PRG evolution, with NGC 3718 in the initial stage, NGC 2685 in the intermediate stage, and NGC 4262 representing the final stage. This study concludes that PRGs undergo various evolutionary stages, as evidenced by the observed features in the ring and host components. NGC 3718, NGC 2685, and NGC 4262 represent different stages of this evolution, highlighting the dynamic nature of PRGs and emphasising the importance of studying their evolutionary processes to gain insights into galactic formation and evolution. The Author(s), 2025. -
High-resolution spectral analysis of three high-latitude carbon stars
We present the results of a detailed high-resolution spectroscopic analysis (SUBARU/HDS spectra, R 50 000) of three faint high-latitude carbon stars HE 1104 0957, HE 1205 0521, and HE 1244 3036. Our estimated metallicity for these objects is 2.96, 2.63, and 2.49, respectively. The surface chemical compositions of the objects are found to be characterised by enhanced carbon and heavy elements, such as Y, Ba, La, and Ce. Using the classification criteria for carbon-enhanced metal-poor (CEMP) stars the objects HE 1104 0957 and HE 1205 0521 could not be classified into any known CEMP sub-classes, whereas the object HE 1244 3036 is found to be likely a CEMP-s star. The observed abundance patterns in HE 1244 3036 are also found to match well with the yields of a 2 M AGB star with [Fe/H] = 2.50. Although our kinematic analysis indicates that the objects belong to the halo population, the elemental abundance ratios of HE 1104 0957 and HE 1205 0521 do not match well with those of typical halo objects. Estimated elemental abundances are presented, and kinematic properties of the stars are discussed. The Author(s), 2025. -
Designing a One-Pot Ternary Fe-Mn-Zn Oxide Positive Electrode with Enhanced Energy-Storage Properties for Hybrid Supercapacitors
In recent years, ternary metal-oxide nanocomposite-based active electrodes have been investigated more effectively for supercapacitor applications due to the existence of a greater number of electroactive sites and the synergistic effect of three different transition-metal ions. Herein, Fe-Mn-Zn oxide ternary nanocomposites are synthesized using a simple and cost-effective one-pot hydrothermal approach. The characterizations of XRD, FTIR, FESEM, EDX, HRTEM, and XPS are analyzed for the synthesized Fe-Mn-Zn oxide nanocomposites to study their phases, functional groups, morphologies, purity, and binding energies. The electrochemical characteristics for the developed electrodes are studied in a three-electrode technique using CV, GCD, EIS, and a cyclic stability test. As expected, the ternary nanocomposite electrode of Fe-Mn-Zn oxide reveals a maximum specific capacitance (Cspc1) of 1673.4 F/g in comparison to other developed electrodes of ZnFe2O4 (271.7 F/g) and ZnMn2O4 (412.7 F/g) at the appropriate scan rate of 10 mV/s. In addition, the Fe-Mn-Zn oxide ternary nanocomposite active electrode exhibits 2616.25 F/g of total capacitance (qT**), 686.94 F/g of outer capacitance (qO**), and 1929.30 F/g of inner capacitance (qI**) which are determined by Trasatti analysis. Moreover, the fabricated hybrid supercapacitor device provides a good specific capacitance of 320.8 F/g, a high energy density of 75.3 Wh/kg at the power density of 649.9 W/kg at 1 A/g of current density range, and 88.75% of superior capacitive retention over 10,000 cycles at 10 A/g. Therefore, a ternary metal-oxide nanocomposite electrode is proposed to be a promising material for energy-storage devices. 2024 American Chemical Society. -
Utilizing Highly Reactive Lewis Pairs Generated by Oxygen Vacancies in the Cu3Mo2O9 Solid Catalyst for Cycloaddition of CO2 to 1,2-Propanediol
This work emphasizes generating highly reactive Lewis pair sites on CuMo oxides for CO2 activation and utilization in the cyclization reaction to produce propylene carbonate from 1,2-propanediol. The CuMo oxides were synthesized by enabling the oxygen vacancies that enhance the catalytically active sites, resulting in the formation of metastable cations (Mo5+ and Cu1+) and oxygen vacancies. Under ethanol-PEG-400 medium, the pure phase of Cu3Mo2O9 obtained at 500 C exposed maximum defects without any secondary phase compared to other screened catalysts. The experimental and theoretical investigations provide evidence for determining and correlating the characteristics of active sites with catalytic performance. The catalysts were extensively characterized along with density functional theory (DFT) studies, which revealed the presence of defect centers as one of the key factors in the enhanced activity. From the chemical bonding analysis, i.e., Crystal Orbital Hamiltonian Population (COHP) and Electron Localization Function (ELF), the CO2 molecule is known to form a strong chemisorption interaction with the catalyst surface that is facilitated by the oxygen vacancy/Lewis pairs. The Cu-Mo oxide catalyst achieved 99% conversion of 1,2-propanediol and 97% yield of propylene carbonate, outperforming previously reported catalysts. Thus, Cu-Mo oxide was shown to be highly efficient catalyst with good recyclability for 1,2-propanediol and the CO2 reaction. 2025 American Chemical Society. -
Buffer-Induced Electrocatalytic Hydrogen Evolution by a Cobalt Pentadentate Complex in Water
Elucidating proton transfer dynamics in water represents one of the most challenging problems in water splitting reactions due to the presence of multiple proton donors, which complicates the overall reaction kinetics. This study examines the impact of buffer pKa and its concentration on catalytic performance for hydrogen evolution catalyzed by a CoIII complex (1). The results demonstrate that buffer increases the catalytic rate of the hydrogen evolution reaction. This enhanced activity is supported by the number of buffer acids possessing varying pKa values, with 2-(N-morpholino)ethanesulfonic acid yielding the maximum catalytic current. A linear free energy relationship, a characteristic of a Brsted-type mechanism, is observed between the buffers pKa and catalytic rate constants. This substantiates that the rate-limiting step is controlled by the proton delivery mediated by the buffer acids. Moreover, the observed inhibition in catalytic activity at a higher concentration of buffer reveals the possible binding interaction between buffer and the cobalt center, thereby impeding substrate access. These findings underscore the critical role of buffer identity and its concentration in optimizing the proton-dependent catalytic reactions in water. 2026 American Chemical Society -
Keggin-Type H5PMo10V2O40Intercalated MgAl-LDH: Structural Integrity and Bifunctional Electrocatalytic Activity
The development of earth-abundant electrocatalysts is central to sustainable water electrolysis, yet many systems are limited by poor electronic conductivity and inadequate durability. In particular, the high solubility of discrete polyoxometalates (POMs) clusters hinders their direct deployment as stable heterogeneous electrocatalysts. Here, a Keggin-type H5PMo10V2O40 POM is intercalated into MgAl layered double hydroxide (MgAl-LDH) by a formamide-assisted exfoliation-reassembly strategy to afford a POM@MgAl-LDH hybrid. Structural characterization confirms quantitative ion exchange of POM anions into the LDH galleries and an increase of the basal spacing to 9.210.5 Density functional theory calculations indicate thermodynamically favorable intercalation (?E ? ?2.3 eV per formula unit) and predict an equilibrium interlayer distance that matches the experiment. The hybrid exhibits a BET surface area of 50.6 m2 g1 and hierarchical porosity. In 1.0 M KOH, POM@MgAl-LDH functions as a bifunctional electrocatalyst, affording hydrogen and oxygen evolution overpotentials of 215 and 411 mV at 10 mA cm2, respectively, with ?97% current retention over 12 h of electrolysis. These results suggest that spatial confinement of redox-active POM clusters within an earth-abundant MgAl-LDH host reduces POM loss into solution and improves the electrocatalytic response of LDH framework, offering a practical route to nonprecious-metal bifunctional electrocatalysts for alkaline water splitting. 2026 American Chemical Society -
Investigating the Electrochemical Behavior of Flowerlike-Co-Pi-Decorated Ti3C2TxMXene for Cathodic CO2Utilization: A Sustainable Approach
The rising CO2 concentration in the atmosphere has sparked the need for research communities and industries to shift toward embracing technologies prioritizing CO2 conversion and utilization. This research presents the fabrication of flowerlike cobalt-inorganic phosphate-decorated Ti3C2Tx MXene-modified carbon fiber paper (Co-Pi/Ti3C2Tx/CFP) electrode for electrochemical CO2 fixation via benzyl chloride transformation to produce industrially and pharmaceutically important phenylacetic acid (PAA). The multilayered Ti3C2Tx, having a large specific surface area, functions as the nucleation centers for the deposition of Co-Pi and enhances its physical, chemical, and electron transmission attributes. The Co-Pi anchored to Ti3C2Tx in turn modifies the interlayer properties of MXene, prevents restacking of the layered MXene structure, provides additional electrocatalytic sites, and escalates the electrocatalytic efficiency. Cyclic voltammetry and potentiostatic electrolysis studies revealed a higher current response, lower reduction potential, and increased productivity at the Co-Pi/Ti3C2Tx/CFP electrode for benzyl chloride transformation with CO2 coupling, yielding the desired carboxylic acid. Under optimal conditions, potentiostatic electrolysis at ?1.6 V for 8 h yielded up to 62% PAA, following a diffusion-controlled two-electron reduction mechanism. Furthermore, the electrodes showed good repeatability, reproducibility of electrochemical responses, and excellent stability over 60 days. 2025 American Chemical Society -
Boosting Surface Coverage of CO Intermediates through Multimetallic Interface Interactions for Efficient CO2 Electrochemical Reduction
Given the inherent challenges of the CO2 electroreduction (CO2ER) reaction, solely from CO2 and H2O, it is desirable to develop selective product formation pathways. This can be achieved by designing multimetallic nanocomposites that provide optimal CO coverage, allowing for tunability in the product formation. In this work, Ag and Zn codoped-SrTiO3 (ZAST) composite immobilized carbon black (CB)-modified GCE working electrode (ZAST@CB/GCE) was developed for the electrochemical conversion of CO2 to multicarbon products. The complete reaction was carried out in a CO2-saturated aqueous system of 0.5 M KHCO3 electrolyte. A potential-dependent product selectivity was suggested based on the NMR results, wherein raising the potential value enhanced the formation of liquid products such as acetone and alcohols while suppressing competitive HER. The total Faradaic efficiency for liquid products reached an impressive 97% at a potential of ?0.6 V vs. RHE. This represents a significant advancement in acetone production pathways and valorization of CO2ER technology. 2025 American Chemical Society. -
Unveiling the Redox Characteristics of Rutin Trihydrate-Canvas-Based Sensor for Hydrazine Sensing in Water Samples
The inclusion of redox mediators into electrocatalytic systems facilitates rapid electron shuttling kinetics and boosts the overall catalytic performance of the electrode. This approach overcomes the sluggish reaction dynamics associated with direct electron transfer, which may be impeded by restricted analyte access to the electrodes active sites. In contrast to conventional synthetic redox mediators, naturally sourced phytomolecule rutin trihydrate (RT), extracted from apple juice, offers potential ecological advantages. This bands with green chemistry principles and sustainability in electroanalytical approaches. The current work presents an eco-friendly and direct electrochemical approach to fabricate a redox-active RT-immobilized MWCNT-infused PEDOT hybrid material-modified glassy carbon electrode (GCE/MWCNT + PEDOT@RT). The developed electrode showcased a sharp and stable redox signal at E0 = 0.63 V vs Ag/AgCl with no surface-fouling characteristics. The efficacious functionalization of RT onto MWCNT + PEDOT was corroborated by a remarkable increase in the surface characteristics, enhanced electrochemical current responses, and low charge transfer resistance. The GCE/MWCNT + PEDOT@RT exhibited highly selective and sensitive sensing responses toward the toxic and potentially carcinogenic hydrazine (HZ) via cyclic voltammetry and differential pulse voltammetry techniques, yielding a low detection limit (DL) of 1.02 ?M and a sensitivity of 0.032 ?A ?M-1 in a linear dynamic range between 0 and 1350 ?M. In addition, the method was highly efficient for HZ detection in real samples of tanker, tap, and wastewater samples, producing a good recovery of ?98%. 2025 American Chemical Society. -
Electroreduction of CO2 to Methanol Using a Coordination-Moiety-Anchored Carbon-Based Electrode
Electrochemical reduction of carbon dioxide (CO2ER) has gained wide attention lately because of its potential to create a closed carbon loop, offering a sustainable solution toward environmental as well as energy crisis. However, the key challenge lies in the selective conversion of CO2 into electrofuels, such as methanol, which necessitates six proton-coupled electron transfers. In this work, we report the first instance of an electrochemically prepared Cu-coordinated 2,5-dimercapto-1,3,4-thiadiazole-modified carbon fiber paper electrode (CDM@CFP). The hence-engineered novel electrode was applied for the CO2ER reaction to produce methanol exclusively with an F.E. of 59.6% at a low potential of ?0.73 V versus RHE. Unlike most of the copper-based electrocatalysts, which result in multiple hydrocarbons, here, we have optimized a potential-dependent selectivity for maximum efficiency, which is a significant milestone in the field. 2025 American Chemical Society. -
Electrochemical Transformation of Thiol-Iodine-Based Reactions toward Multiplexed Sensing Applications for Plant-Stress Hormone and Environmental Contaminant
Functionalized thiophenes are potential electroactive species that serve as efficient molecular electrochemical sensors. This work describes the fabrication of a 3-thiophene acetic acid (TAA)-modified screen-printed carbon electrode/multi-walled carbon nanotube (SPCE/MWCNT) platform via a facile electrochemical method in an aqueous medium. The effectual PT-Redox (product of TAA formed postpotentiostatic polarization) integration over SPCE/MWCNT was confirmed through various spectroscopic and electrochemical investigations. The SPCE/MWCNT showcased exceptional interaction with PT-Redox, creating a resilient platform for its precise binding, thereby enhancing the electrodeelectrolyte electroactive region, topographic roughness, electron conductivity, host response, and comprehensive electrochemical properties. The as-prepared electrode (SPCE/MWCNT@PT-Redox) was employed for the selective detection and quantification of glutathione (GT) as well as hydrazine (HyD) in an aqueous medium. The sensor showed excellent electrocatalytic oxidation responses toward these analytes, yielding a good sensitivity of 0.32 ?A mM1, a low detection limit (DL) of 0.225 ?M, a broad linear dynamic window of 0400 ?M for GT, a high sensitivity of 0.13 ?A mM1, a low DLof 0.56 ?M, and a linear window of 0350 ?M for HyD, obtained via the differential pulse voltammetry (DPV) technique. This substantiates that the modification with PT-Redox significantly boosted the electrodes interfacial activity and catalytic potential. Furthermore, the electrode exhibited robust antifouling and anti-interference traits, suggesting the composites enhanced stability and sensing capabilities for real-world applications. The captivating features, including excellent specificity, fast response dynamics, and simple sample preparation necessities of the proposed system, reveal a promising platform that accomplishes significant potential in futuristic sensing applications. 2025 American Chemical Society