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Novel Applications of Graphene and its Derivatives: A Short Review
Graphene, a layered allotropic form of graphitic carbon, has fascinated the scientific world since its discovery. Its unique structural, physical, chemical, mechanical, and electrical properties find application in many areas. Because of its large surface area and its apt electrical property, it is used in electromagnetic interference shielding. With excellent carrier mobility, it is used for sensing purposes. Mechanical strength and elastic properties coupled with its lightweight make graphene a promising material as a supercapacitor. The 2-dimensional structural properties of the graphene layers can be used for the purification treatment of water and gas. The number of research in graphene applications is increasing every day, showing the importance and excellency of graphene properties. This short review provides a comprehensive understanding of graphene's properties and progress in electromagnetic interference shielding, sensors, water treatment, energy production, storage, and conversion applications such as supercapacitors, fuel cells, solar cells and electrocatalysts. 2023 Bentham Science Publishers. -
Production of anthraquinones from cell and organ cultures of Morinda species
Abstract: Since ancient times, Morinda species, particularly Morinda citrifolia, have been used for their therapeutic benefits. Iridoids, anthraquinones, coumarins, flavonoids, lignans, phytosterols, and carotenoids are examples of natural substances with bioactivity. Anthraquinone derivatives are the most significant of these chemicals since they are utilized as natural coloring agents and have a wide range of medicinal functions. Utilizing cell and organ cultures of Morinda species, various biotechnological methods have been developed for the bioproduction of anthraquinone derivatives. The generation of anthraquinone derivatives in cell and organ cultures is summarized in this article. The methods used to produce these chemicals in bioreactor cultures have also been examined. Key points: This review investigates the potential of cell and organ cultures for anthraquinone synthesis. The overproduction of anthraquinones has been addressed using a variety of techniques. The use of bioreactor technologies for anthraquinone manufacturing is highlighted. 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. -
Biotechnological approaches for the production of gymnemic acid from Gymnema sylvestre R. Br.
Abstract : Diabetes is a chronic disease that affects several organs and can be treated using phytochemicals found in medicinal plants. Gymnema sylvestre (Asclepiadaceae) is one such medicinal plant rich in anti-diabetic properties. The plant is commonly known as madhunashini in Sanskrit because of its ability to cure diabetes (sugar). Gymnemic acid(GA) is a phytochemical (a triterpenoid saponin) responsible for the herbs main pharmacological activity. This secondary metabolite has a lot of potential as a phytochemical with pharmacological properties including nephroprotection, hypoglycemia, antioxidant, antimicrobial, and anti-inflammatory. Gymnema has acquired a lot of popularity in recent years due to its low side effects and high efficacy in healing diabetes, which has led to overexploitation by pharmaceutical enterprises for its biomass in the wild for the purification of gymnemic acid. Modern biotechnological techniques involving the establishment of cell and organ cultures from G. sylvestre will assist us in fulfilling the need for gymnemic acid production. The present review provides insights on the establishment of cell and organ cultures for the production of a potent antidiabetic molecule gymnemic acid. Further, the review also delves into the intricacies of the different strategies for improved production of gymnemic acid using various elicitors. There is huge potential for sustainable production of gymnemic acid which could be met by establishment of bioreactor scale production. Understanding and engineering the biosynthetic pathway could also lead to improved GA production. Key points: Gymnemic acid is one of the potential anti-diabetic molecules from madhunashini Cell and organ culture offers potential approach for gymnemic acid production Elicitation strategies have improved the gymnemic acid production Graphical Abstract: [Figure not available: see fulltext.] 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. -
The role of meditation and mindfulness in the management of polycystic ovary syndrome: a scoping review
Polycystic Ovary Syndrome (PCOS) presents multifaceted challenges affecting womens reproductive, metabolic, and psychological systems, consequently impacting their psychological and emotional well-being. The utilization of meditation and mindfulness interventions (MMIs) is found to be increasing for the management of PCOS. This scoping review systematically explored the current literature to identify the type and application of MMIs for PCOS management. A systematic search of literature was conducted using CINAHL, PsycINFO, Scopus, MEDLINE, and PubMed databases for identifying studies conducted on the usage of MMIs in women diagnosed with PCOS, irrespective of age. The comprehensive search identified 14 trials (comprising 17 citations) meeting inclusion criteria, involving 723 participants across various age groups. Among these, nine were randomized controlled trials (RCTs), while the remaining comprised non-RCTs. Several types of MMIs, including Rajayoga of Brahmakumaris, Yoga Nidra, OM cyclic meditation, unspecified forms of meditation, mindfulness-based stress reduction programs, mindful yoga, and mindfulness-based activities, were used. Outcomes were predominantly assessed in psychological domains (n=11), followed by anthropometric (n=9), quality of life (n=7), and metabolic metrics (n=7). The review findings suggest the integration of meditation with conventional treatment modalities. Preliminary data indicate that MMIs have the potential to improve psychosocial well-being and quality of life among PCOS-affected women. However, adequately powered studies with extended follow-up periods are required to investigate the mechanisms and therapeutic efficacy of MMIs, particularly concerning reproductive outcomes and weight management. Furthermore, diligent monitoring and reporting of adverse events and adherence are essential for a comprehensive understanding of MMI utilization in PCOS management. Copyright 2024 Rao, Pena, James, Phadke, Grover, Blendis, Choudhary and Kampegowda. -
An In-Depth Analysis of Collision Avoidance Path Planning Algorithms in Autonomous Vehicles
Path planning is a way to define the motion of an autonomous surface vehicle (ASV) in any existing obstacle environment to enable the vehicle's movement by setting directions to avoid that can react to the obstacles in the vehicle's path. A good, planned path perceives the environment to the extent of uncertainty and tries to build or adapt its change in the path of motion. Efficient path planning algorithms are needed to alleviate deficiencies, that are to be modified using the deterministic path that leads the ASV to reach a goal or a desired location while finding optimal solution has become a challenge in the field of optimization along with a collision-free path, making path planning a critical thinker. The traditional algorithms have a lot of training and computation, making it difficult in a realistic environment. This review paper explores the different techniques available in path planning and collision avoidance of ASV in a dynamic environment. The objective of good path planning and collision avoidance for a dynamic environment is compared effectively with the existing obstacles movement of different vehicles. Different path planning technical approaches are compared with their performance and collision avoidance for unmanned vehicles in marine environments by early researchers. This paper gives us a clear idea for developing an effective path planning technique to overcome marine accidents in the dynamic ocean environment while choosing the shortest, obstacle-free path for Autonomous Surface Vehicles that can reduce risk and enhance the safety of unmanned vehicle movement in a harsh ocean environment. 2024 Bentham Science Publishers.