MnO2 Nanoclusters Decorated on GrapheneModified Pencil Graphite Electrode for Non-Enzymatic Determination of Cholesterol
- Title
- MnO2 Nanoclusters Decorated on GrapheneModified Pencil Graphite Electrode for Non-Enzymatic Determination of Cholesterol
- Creator
- Rison S.; Akshaya K.B.; Bhat V.S.; Shanker G.; Maiyalagan T.; Joice E.K.; Hegde G.; Varghese A.
- Description
- Electrochemically deposited MnO2 on graphene coated Pencil Graphite Electrode (PGE) has been used to develop a facile electrochemical sensor for the determination of Cholesterol. Cyclic voltammetric (CV) studies and electrochemical impedance spectroscopic (EIS) technique were used to investigate the electrochemical properties of the modified sensing platform. The physicochemical properties of the modified electrodes were characterized by X-ray photoelectron spectroscopy (XPS), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR). The experimental conditions such as effect of scan rate, concentration and pH were optimized. The linear dynamic range for the determination of Cholesterol was found to be 120?10 M2400?10 M under optimum conditions. The ultralow level of detection limit (0.42 nM) demonstrates the high sensitivity of the proposed method. The developed method was successfully applied for the non-enzymatic determination of Cholesterol in human blood samples at ultralow levels. 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
- Source
- Electroanalysis, Vol-32, No. 10, pp. 2128-2136.
- Date
- 2020-01-01
- Publisher
- Wiley-VCH Verlag
- Subject
- Cholesterol; Electrooxidation; Graphene; MnO2; Pencil graphite electrode
- Coverage
- Rison S., Christ Academy Institute for Advanced Studies, Christ Nagar, Bangalore, 560083, India, Department of Chemistry, CHRIST Deemed to be University, Bangalore, 560029, India; Akshaya K.B., Department of Chemistry, CHRIST Deemed to be University, Bangalore, 560029, India; Bhat V.S., Centre for Nano-materials and Displays, B.M.S. College of Engineering, Bull Temple Road, Bengaluru, 560019, India; Shanker G., Department of Chemistry, JnanaBharati Campus, Bangalore University, Bangalore, India; Maiyalagan T., Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur, 603203, India; Joice E.K., Christ Academy Institute for Advanced Studies, Christ Nagar, Bangalore, 560083, India; Hegde G., Centre for Nano-materials and Displays, B.M.S. College of Engineering, Bull Temple Road, Bengaluru, 560019, India; Varghese A., Department of Chemistry, CHRIST Deemed to be University, Bangalore, 560029, India
- Rights
- Restricted Access
- Relation
- ISSN: 10400397; CODEN: ELANE
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Rison S.; Akshaya K.B.; Bhat V.S.; Shanker G.; Maiyalagan T.; Joice E.K.; Hegde G.; Varghese A., “MnO2 Nanoclusters Decorated on GrapheneModified Pencil Graphite Electrode for Non-Enzymatic Determination of Cholesterol,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 25, 2025, https://archives.christuniversity.in/items/show/16222.