Facile Synthesis of Polymer Dot and Its Antibacterial Action Against Staphylococcus aureus
- Title
- Facile Synthesis of Polymer Dot and Its Antibacterial Action Against Staphylococcus aureus
- Creator
- Mathew A.A.; Joseph N.; Daniel E.C.; Balachandran M.
- Description
- Antimicrobial resistance (AMR) rising from nosocomial infections is an escalating threat to human life nowadays due to the overuse of drugs. The multidrug-resistant pathogenic bacteria have increased morbidity and mortality rates, becoming a crucial global clinical challenge. Gram-positive Staphylococcus aureus bacteria is one of the nosocomial pathogens that cause severe invasive diseases and skin infections to human health worldwide. Herein, a non-conjugated polymer dot (NCPD) was synthesized from less toxic and biocompatible polyvinyl alcohol (PVA) via hydrothermal treatment. The fluorescence of the polymer dots was enhanced by nitrogen doping. The as-synthesized nitrogen-doped polymer dots (PDs) exhibit excitation-dependent luminescence emission and show green color fluorescence under UV light. The average size of the synthesized functionalized non-conjugated polymer dot is obtained as 4.08nm, and they exhibit an amorphous structure. No antibacterial property was observed for bulk polymer, but the doped polymer dots showed antibacterial activity against Gram-positive Staphylococcus aureus bacteria. The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd 2024.
- Source
- Springer Proceedings in Materials, Vol-27, pp. 313-317.
- Date
- 2024-01-01
- Publisher
- Springer
- Subject
- Antibacterial; Fluorescence; Nitrogen doping; Polymer dot
- Coverage
- Mathew A.A., CHRIST (Deemed to be University), Bengaluru, 560029, India; Joseph N., CHRIST (Deemed to be University), Bengaluru, 560029, India; Daniel E.C., Kristu Jayanti College (Autonomous), Bengaluru, 560077, India; Balachandran M., CHRIST (Deemed to be University), Bengaluru, 560029, India
- Rights
- Restricted Access
- Relation
- ISSN: 26623161
- Format
- Online
- Language
- English
- Type
- Book chapter
Collection
Citation
Mathew A.A.; Joseph N.; Daniel E.C.; Balachandran M., “Facile Synthesis of Polymer Dot and Its Antibacterial Action Against Staphylococcus aureus,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 23, 2025, https://archives.christuniversity.in/items/show/18149.