Microbial Enzymes for Synthesis of Chiral Drug Intermediates
- Title
- Microbial Enzymes for Synthesis of Chiral Drug Intermediates
- Creator
- Arun K.B.; Sindhu R.; Nair B.G.; Parameswaran B.; Pandey A.; Awasthi M.K.; Kuddus M.; Madhavan A.
- Description
- Microbes or microbial enzymes can catalyze the synthesis of bioorganic compounds, and this process is defined as biocatalysis. Biocatalysis has become an essential technique in organic biotransformation, typically applied in chemical industries. Biocatalysts generally show high activity and excellent enantio, stereo, regio, and chemo-selectivity. They offer practical and cost-effective ways to synthesize semi-synthetic analogues and novel drug molecules. Many bacteria and fungi-derived enzymes could catalyze highly specific hydroxylations of various substrates that are highly complex to synthesize by chemical methods. This chapter details and discusses different biocatalytic microbial platforms that permit to produce the chiral drug intermediates. 2023 selection and editorial matter, Ranjna Sirohi, Amit Kumar Rai, Luciana Porto de Souza Vandenberghe, and Binod Parameswaran; individual chapters, the contributors
- Source
- Microbial Enzymes and Metabolites for Health and Well-Being, pp. 41-52.
- Date
- 2023-01-01
- Publisher
- CRC Press
- Coverage
- Arun K.B., Department of Life Sciences CHRIST (Deemed to be University), Karnataka, Bengaluru, India; Sindhu R., Department of Food Technology, TKM Institute of Technology, Kerala, Kollam, India; Nair B.G., School of Biotechnology, Amrita Vishwa Vidyapeetham Amritapuri, Kerala, Kollam, India; Parameswaran B., Microbial Processes and Technology Division CSIR, National Institute for Interdisciplinary Science and Technology (NIIST), Kerala, Thiruvananthapuram, India; Pandey A., Center for Innovation and Translational Research CSIR Indian Institute of Toxicology Research (CSIR-IITR), India, Centre for Energy and Environmental Sustainability, Uttar Pradesh, Lucknow, India; Awasthi M.K., Awasthi College of Natural Resources and Environment, Northwest A&F University, Shaanxi, Yangling, China; Kuddus M., Department of Biochemistry, University of Hail, Saudi Arabia; Madhavan A., School of Biotechnology, Amrita Vishwa Vidyapeetham Amritapuri, Kerala, Kollam, India
- Rights
- Restricted Access
- Relation
- ISBN: 978-100088826-3; 978-103243619-7
- Format
- Online
- Language
- English
- Type
- Book chapter
Collection
Citation
Arun K.B.; Sindhu R.; Nair B.G.; Parameswaran B.; Pandey A.; Awasthi M.K.; Kuddus M.; Madhavan A., “Microbial Enzymes for Synthesis of Chiral Drug Intermediates,” CHRIST (Deemed To Be University) Institutional Repository, accessed April 18, 2025, https://archives.christuniversity.in/items/show/18479.