Saccharomyces - eukaryotic probiotic for human applications

Title

Saccharomyces - eukaryotic probiotic for human applications

Creator

Malaviya A.; Malviya S.; Agarwal A.; Mishra M.; Dalmida V.

Description

Probiotics are viable microorganisms which are meant to confer health benefits to host after ingestion. Any probiotic strain has a special characteristic to survive in the extremely acidic and hostile conditions of stomach and intestine. Among all the commercially available probiotic strains, prokaryotes constitute the bulk of it, with quite a few belonging to eukaryotic yeasts. Eukaryotic probiotics are very limited and currently there are only two yeast strains (Saccharomyces boulardii and Kluyveromyces sp.), which are approved for human consumption and are available commercially in market. S. boulardii has been reported to have tremendous therapeutic potential. The main mechanism of action for S. boulardii includes strong antagonistic effect against a number of enteric pathogens, trophic effects on the intestinal mucosa, neutralisation of bacterial toxins as well as modification of host cell signaling pathways involved in inflammatory and non-inflammatory intestinal disease. Pertaining to these advantages, S. boulardii have been reported to be exceptionally effective against diarrheal diseases and intestinal inflammatory conditions including inflammatory bowel disease (IBD). Increasing scientific reports confirming the therapeutic potential of eukaryotic probiotics and their advantages over prokaryotic probiotic strains have dramatically increased the worldwide interest in these probiotics. 2019 Scrivener Publishing LLC.

Source

A Handbook on High Value Fermentation Products, Volume 2: Human Welfare, pp. 211-229.

Date

2019-01-01

Publisher

wiley

Subject

Diarrheal diseases; Eukaryotic probiotic; Inflammatory bowel disease; Saccharomyces boulardii

Coverage

Malaviya A., Department of Chemistry, Christ (Deemed to be University), Hosur Road, Bengaluru, 560029, India; Malviya S., National Centre for Biological Sciences, Tata Institute of Fundamental Research, GKVK Campus, Bellary Road, Bengaluru, 560065, India; Agarwal A., Department of Chemistry, Christ (Deemed to be University), Hosur Road, Bengaluru, 560029, India; Mishra M., Department of Chemistry, Christ (Deemed to be University), Hosur Road, Bengaluru, 560029, India; Dalmida V., Department of Chemistry, Christ (Deemed to be University), Hosur Road, Bengaluru, 560029, India

Rights

Restricted Access

Relation

ISBN: 978-111955538-4; 978-111955483-7

Format

Online

Language

English

Type

Book chapter

Identifier

https://doi.org/10.1002/9781119555384.ch11

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102325810&doi=10.1002%2f9781119555384.ch11&partnerID=40&md5=eedaa8e98358e1f8182385f5972ded2e