Synthetic approaches toward butenolide-containing natural products
- Title
- Synthetic approaches toward butenolide-containing natural products
- Creator
- Tadiparthi K.; Venkatesh S.
- Description
- The butenolide scaffold is ubiquitous in many natural products and pharmaceutical active ingredients. These candidates appeal to organic chemists for the synthesis of products with various biological activities. This review delineates the efforts made in the total synthesis of natural products based on the butenolide core unit such as umbelactones, akolactones, ansepcinolide, lissoclinolide, fugomycin, and muricadienin. Many of the reported syntheses involve chiral pool, enzyme resolution, and chiral auxiliary, or enantioselective approaches as a key step. Overall, this review highlights the synthetic methods involved in the preparation of butenolide-containing molecules and aims to increase the profile of such scaffolds to the synthetic community. 2022 Wiley Periodicals LLC.
- Source
- Journal of Heterocyclic Chemistry, Vol-59, No. 8, pp. 1285-1307.
- Date
- 2022-01-01
- Publisher
- HeteroCorporation
- Coverage
- Tadiparthi K., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, India; Venkatesh S., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, India
- Rights
- Restricted Access
- Relation
- ISSN: 0022152X; CODEN: JHTCA
- Format
- Online
- Language
- English
- Type
- Review
Collection
Citation
Tadiparthi K.; Venkatesh S., “Synthetic approaches toward butenolide-containing natural products,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 24, 2025, https://archives.christuniversity.in/items/show/21520.