ItemArticle

Anti-inflammatory and anti-diabetic activities of lanthanum oxide nanoparticles using Plectranthus amboinicus leaf extract

Title
Anti-inflammatory and anti-diabetic activities of lanthanum oxide nanoparticles using Plectranthus amboinicus leaf extract
Creator
Vijayan, Kousalya Devi; Alagarsamy, Nivedhitha Bharathi; Sangaraju, Sambasivam; Arumugam, Venkatesan; Muthusamy, Krishna Kumar; Sakkarapani, Sudhahar
Description
Lanthanum oxide nanoparticle (La2O3 NPs) were synthesized by co-precipitation technique using Plectranthus amboinicus (P. amboinicus ) leaf extract. A yellowish green color was observed after the addition of leaf extract to the NaOH solution. The synthesis of nanoparticles plays a vital role in the field of science and technology. The cubic structure of the La2O3 was confirmed by Powder XRD. The functional groups present in the NPs were confirmed by FT-IR spectroscopy. The absorbance spectrum was observed at 274nm in the wavelength range of 230850nm. The calculated band gap value was 4.32eV. The structural morphology of La2O3 NPs was observed as cubic and irregular shape obtained from SEM image and EDAX spectrum which confirms the presence of La and O elements. The average particle sizes of the NPs were observed to be 40.22nm analyzed by high resolution transmission electron microscopy (HR-TEM) analysis. The main objective of this research work was focused on prepared La2O3 NPs act as a potential inhibitor to handle various inflammations and diabetes problems. Bovine serum albumin (BSA) denaturation approach produced a strong anti-inflammatory response with 92.89% inhibition at 500g/mL while ?-amylase showed significant antidiabetic activity of about 94.55% inhibition at 500g/mL. These results suggest that the green synthesized nanoparticles can be used for ?-amylase and BSA denaturation inhibitory activities, which may be crucial for biomedical applications. The Author(s), under exclusive licence to Society for Plant Biochemistry and Biotechnology 2026.
Source
Journal of Plant Biochemistry and Biotechnology;
Date
01-01-2026
Publisher
Springer
Subject
Anti-diabetic; Anti-inflammatory; Green synthesis; Lanthanum oxide NPs; Morphology; Structural
Coverage
Vijayan K.D., Department of Physics, Alagappa University, Karaikudi, 630003, India; Alagarsamy N.B., Department of Physics, Alagappa University, Karaikudi, 630003, India; Sangaraju S., National Water and Energy Center, United Arab Emirates University, Al Ain, 15551, United Arab Emirates; Arumugam V., Department of Physics, Panimalar Engineering College, Tamilnadu, Chennai, 600123, India; Muthusamy K.K., Department of Physics and Electronics, CHRIST (Deemed to be University), Bengaluru, 560029, India; Sakkarapani S., Department of Physics, Alagappa University, Karaikudi, 630003, India
Rights
Restricted Access; Hardcopy may be available in the library
Relation
ISSN: 9717811; CODEN: JPBBE
Format
online
Language
English
Type
Article

Citation

Vijayan, Kousalya Devi; Alagarsamy, Nivedhitha Bharathi; Sangaraju, Sambasivam; Arumugam, Venkatesan; Muthusamy, Krishna Kumar; Sakkarapani, Sudhahar, “Anti-inflammatory and anti-diabetic activities of lanthanum oxide nanoparticles using Plectranthus amboinicus leaf extract,” CHRIST (Deemed To Be University) Institutional Repository, accessed June 18, 2026, https://archives.christuniversity.in/items/show/22049.

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