ItemArticle

Green synthesis of NiTiO? and tartaric acid-coated NiTiO? nanoparticles using Tagetes erecta: Characterization and biological applications

Title
Green synthesis of NiTiO? and tartaric acid-coated NiTiO? nanoparticles using Tagetes erecta: Characterization and biological applications
Creator
Thangavelu, Indumathi; Tadepalli, Srinivas; Kasibatla, Murthy S.
Description
This study investigated the environmentally friendly synthesis, structural characterization, and biomedical potential of nickel titanate (NiTiO?) nanoparticles (NPs) prepared using Tagetes erecta (marigold) flower extract, with particular emphasis on their tartaric acid-coated, functionalized derivative (NiTiO?-T NPs). Structural analyses via FTIR spectroscopy revealed functional groups characteristic of the tartaric acid coating on NiTiO?-T NPs, while XRD confirmed the crystalline hexagonal phase for both NiTiO? and NiTiO?-T NPs. FESEM images demonstrated that both types of NPs exhibited uniform, spherical morphologies. Biomedical evaluations highlighted the enhanced efficacy of NiTiO?-T NPs, which achieved 85.2 % DPPH radical scavenging at 100 ?g/mL, significantly outperforming uncoated NiTiO? NPs (72.4 %). Antimicrobial testing against various pathogens showed that NiTiO?-T NPs generated larger inhibition zones compared to their counterparts, effectively targeting Gram-positive bacteria (S. aureus, B. subtilis), Gram-negative bacteria (E. coli, P. aeruginosa), and fungi (C. albicans). Further analysis revealed notably lower minimum inhibitory concentrations (MICs: 1000 ?g/mL) and minimum bactericidal concentrations (MBCs: 1500 ?g/mL) for NiTiO?-T NPs, confirming their potent bactericidal action. These findings position tartaric acid-functionalized NiTiO?-T NPs as promising candidates for dual-functional therapeutic applications. 2025
Source
Journal of Molecular Structure;Volume;1355;Issue;;Article No.;144941;
Date
01-01-2026
Publisher
Elsevier B.V.
Subject
Antibacterial activity; DPPH; NiTiO3-T NPs; Tagetes erecta
Coverage
Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, 560029, India; Tadepalli S., Department of Chemical Engineering, College of Engineering, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11432, Saudi Arabia; Kasibatla M.S., Department of Chemistry, Applied Science Cluster, University of Petroleum and Energy Studies, Uttarakhand, Dehradun, 248007, India
Rights
Restricted Access; Hardcopy may be available in the library
Relation
ISSN: 222860; CODEN: JMOSB
Format
online
Language
English
Type
Article

Citation

Thangavelu, Indumathi; Tadepalli, Srinivas; Kasibatla, Murthy S., “Green synthesis of NiTiO? and tartaric acid-coated NiTiO? nanoparticles using Tagetes erecta: Characterization and biological applications,” CHRIST (Deemed To Be University) Institutional Repository, accessed June 19, 2026, https://archives.christuniversity.in/items/show/22409.

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