Phytochemical profiling and evaluation of antioxidant and anti-inflammatory activities of Ipomoea alba L.

Title

Phytochemical profiling and evaluation of antioxidant and anti-inflammatory activities of Ipomoea alba L.

Creator

Harshitha, K.R.; Xavier, Jobi

Description

Plant-based medicine has been one of the oldest therapeutic practices in India and continues to offer valuable treatments for various ailments. Ipomoea alba, commonly known as morning glory, belongs to the family Convolvulaceae and is native to the tropical and subtropical regions of North and South America. It is renowned for its large, fragrant, nocturnal blooms, this plant holds significant potential in traditional medicine, particularly for managing gastrointestinal disorders, inflammation, and skin conditions. The nutrient content of Ipomoea alba leaves and seeds has demonstrated promising health benefits. This study investigated the phytochemical profile of Ipomoea alba leaves using three solvents: water, methanol, and chloroform. Phytochemical analysis confirmed the presence of carbohydrates, proteins, alkaloids, flavonoids, saponins, and tannins. HPLC analysis identified the presence of phenols in the aqueous extract, albeit in small quantities. Among the three extracts,the methanolic extract exhibited the highest antioxidant activity, as determined by DPPH, ABTS, and FRAP assays. Anti-inflammatory activity, assessed using a proteinase inhibitory assay, demonstrated that the methanolic extract showed the greatest inhibition at lower concentrations compared to the aqueous and chloroform extracts. The results suggest that the antioxidant and anti-inflammatory properties of Ipomoea alba may hold potential applications in cancer prevention and treatment. Future studies will aim to evaluate its cytotoxic effects, thereby exploring its potential role in cancer therapy. The Author(s).

Source

Plant Science Today;Volume;12;Issue;2;

Date

01-01-2025

Publisher

Horizon e-Publishing Group

Subject

anti-inflammatory activity; antioxidants; HPLC analysis; Ipomoea alba; phytochemicals

Coverage

Harshitha K.R., Life science, Christ (deemed to be University), Karnataka, Bangalore, 560 029, India; Xavier J., Life science, Christ (deemed to be University), Karnataka, Bangalore, 560 029, India

Rights

All Open Access; Gold Open Access; Green Open Access

Relation

ISSN: 23481900;

Format

online

Language

English

Type

Article

Identifier

https://doi.org/10.14719/pst.6231

https://www.scopus.com/pages/publications/105008431992?origin=resultslist