ItemArticle

Metabolite profiling and bioactivity assessment of diverse endophytic fungi from the endangered plant, Nilgirianthus ciliatus

Title
Metabolite profiling and bioactivity assessment of diverse endophytic fungi from the endangered plant, Nilgirianthus ciliatus
Creator
Priyadarshini, Pragyan; Sarojini, Suma
Description
Endophytic fungi are potential sources of bioactive compounds with therapeutic properties. This study investigated the fungal endophytes associated with Nilgirianthus ciliatus, an endangered medicinal plant, to discover its secondary metabolites and bioactivities. Molecular analysis revealed the prominent species to be Aspergillus niger, Didymella sp., Trichoderma viride, Bipolaris zeicola and Nigrospora sphaerica. Alkaloids, flavonoids, phenolics, terpenes and saponins were detected in ethyl acetate extracts employing phytochemical screening. Didymella sp. has showed the highest level of antioxidant activity, demonstrating strong DPPH radical scavenging and reduction capability. T. viride had strong antibacterial action against Klebsiella pneumoniae and Escherichia coli, meanwhile Didymella sp. and N. sphaerica were most effective against E. coli. GC-MS analysis uncovered many bioactive chemicals, including trans-farnesol and pentadecanoic acid, which are renowned for their antibacterial and antioxidant properties. These findings highlight the presence of the rich variety of diverse endophytic fungi harboring such medicinal plants, which offer promising applications in medicine, biotechnology and agriculture as sources of novel bioactive compounds. Further exploration and characterization of these strains could unlock valuable sustainable resources for various industries. The Author(s).
Source
Plant Science Today;Volume;12;Issue;2;
Date
01-01-2025
Publisher
Horizon e-Publishing Group
Subject
antibacterial; antioxidant; didymellanosine; endophytic fungi; Nilgirianthus ciliatus
Coverage
Priyadarshini P., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560 029, India; Sarojini S., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560 029, India
Rights
All Open Access; Gold Open Access; Green Open Access
Relation
ISSN: 23481900;
Format
online
Language
English
Type
Article

Citation

Priyadarshini, Pragyan; Sarojini, Suma, “Metabolite profiling and bioactivity assessment of diverse endophytic fungi from the endangered plant, Nilgirianthus ciliatus,” CHRIST (Deemed To Be University) Institutional Repository, accessed June 18, 2026, https://archives.christuniversity.in/items/show/23273.

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