ItemArticle

Cognitive Behavioral Therapy for Tinnitus: An Applied Bioanalytical Perspective

Title
Cognitive Behavioral Therapy for Tinnitus: An Applied Bioanalytical Perspective
Creator
Anuja., V.; Rangaswamy, Rashmi; Shukla, Priyanka; Das, Papri; Prabavathy, M.; Lodha, Niraj
Description
Tinnitus affects 1015% of adults worldwide, with 23% experiencing severe and chronic symptoms that impair quality of life. Conventional treatments often provide limited long-term relief, while Cognitive Behavioral Therapy (CBT) has emerged as an evidence-based intervention. The present study evaluated the effectiveness of CBT for tinnitus through an integrated psychometric and bioanalytical approach. A total of 100 participants were randomized into a CBT group (n = 50) and a waitlist control group (n = 50). The CBT program consisted of 12 weekly sessions delivered over 12 weeks. Psychometric assessments included the Tinnitus Handicap Inventory (THI), Hospital Anxiety and Depression Scale (HADS), Pittsburgh Sleep Quality Index (PSQI), and WHOQOL-BREF. Bioanalytical measures comprised functional MRI, EEG, salivary cortisol, heart rate variability (HRV), and inflammatory cytokines (IL-6, TNF-?). The CBT group achieved a 45% reduction in THI scores (58.4 9.2 to 32.1 8.5), while the control group showed only a 5% change. Anxiety and depression scores decreased by 42% and 40%, respectively, and sleep quality improved by 38%. Morning cortisol increased by 48%, HRV improved by 38%, and inflammatory cytokines decreased significantly (IL-6: ?26%; TNF-?: ?19%). Neuroimaging and EEG findings confirmed reduced auditory cortex hyperactivity and abnormal connectivity. These results demonstrate that CBT not only alleviates tinnitus distress but also induces measurable neurophysiological and systemic changes, reinforcing its role as a cornerstone of evidence-based tinnitus management. 2025, Green Publication. All rights reserved.
Source
Journal of Applied Bioanalysis;Volume;11;Issue;4;pp.1077-1084
Date
01-01-2025
Publisher
Green Publication
Subject
Biomarkers; Cognitive Behavioral Therapy; Neuroimaging; Psychometrics; Tinnitus
Coverage
Anuja. V., S. A. Collage of Arts & Science Chennai, Tamil Nadu, India; Rangaswamy R., Christ University, India; Shukla P., School of Arts, Humanities & Social Sciences, CSJMU, Kanpur, India; Das P., Institute of Nursing, Brainware University, West Bengal, India; Prabavathy M., Centre for Differently Abled Persons Bharathidasan University, Tamil Nadu, India; Lodha N., Lodha Hospital and Research Centre, Rajasthan, Pali, India
Rights
All Open Access; Gold Open Access
Relation
ISSN: 2405710X;
Format
online
Language
English
Type
Article

Citation

Anuja., V.; Rangaswamy, Rashmi; Shukla, Priyanka; Das, Papri; Prabavathy, M.; Lodha, Niraj, “Cognitive Behavioral Therapy for Tinnitus: An Applied Bioanalytical Perspective,” CHRIST (Deemed To Be University) Institutional Repository, accessed June 18, 2026, https://archives.christuniversity.in/items/show/23683.

Output Formats