Upconversion nanoparticles for detection of small biomolecules and ions

Title

Upconversion nanoparticles for detection of small biomolecules and ions

Creator

Varghese, Nikita; Das, Raktima; Nair, Yamuna

Description

In recent years, upconversion nanoparticles (UCNPs) have resulted in substantial advances in the area of sensitive and selective detection of small biomolecules and ions. UCNPs possess a unique optical property known as lanthanide upconversion luminescence. This phenomenon enables them to absorb low-energy light from the near-infrared region and subsequently emit higher-energy light in the visible or ultraviolet part of the spectrum. This process, often referred to as the anti-Stokes shift, resists the conventional fluorescence behavior by absorbing lower-energy photons, followed by emission of higher-energy photons. This chapter provides a comprehensive overview of the mechanism of upconversion fluorescence and explores the properties of UCNPs. It then delves into the applications of UCNPs in detection of biomolecules like proteins and amino acids, nucleic acids, and tumor biomarkers, thus facilitating early diagnosis and patient care. Additionally, UCNPs are useful in the detection of ions by altering their surface chemistry to bind selectively to target ions, expanding their utility in environmental monitoring and chemical analysis. 2026 Elsevier Ltd. All rights reserved.

Source

Upconversion Nanoparticles for Biomedical Applications;pp.623-679

Date

01-01-2025

Publisher

Elsevier

Subject

biomolecules; fluorescence sensing; ions detection; Upconversion of nanoparticles

Coverage

Varghese N., Department of Chemistry, Christ University, Karnataka, Bangalore, India; Das R., Department of Chemistry, Christ University, Karnataka, Bangalore, India; Nair Y., Department of Chemistry, Christ University, Karnataka, Bangalore, India

Rights

Restricted Access; Hardcopy may be available in the library

Relation

ISBN: 978-044326661-4; 978-044326662-1;

Format

online

Language

English

Type

Book chapter

Identifier

https://doi.org/10.1016/B978-0-443-26661-4.00017-X

https://www.scopus.com/pages/publications/105023926151?origin=resultslist