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Production of biomass and bioactive compounds from cell and organ cultures of ginseng, He-shou-wu, purple coneflower, and St. John's wort for the use in cosmetic industry
Plants and their products have been utilized as raw materials in the preparation of cosmetics for millennia. Currently, research is being done to find new plant materials that may be used as ingredients in cosmetic preparations, including body sprays, shampoos, conditioners, hair dyes/sprays, and other cosmetics. The plants that are used in the preparation of cosmetic products are usually procured from nature, however, the quality and quantity of bioactive ingredients present in the biomass vary based on the species, environment, and geographical locations from where the material has been procured. In addition, procurement of plant material from natural resources may lead to a shortage of material and even endanger the status of rare plants in the natural environment. Therefore, there is increased interest in the use of plant cell, tissue, and organ cultures (PCTOC) for the production of raw materials and bioactive specialized metabolites. There is also scope for increasing the accumulation of biomass and bioactive compounds in PCTOC by adopting various strategies such as optimization of culture medium, culture environment, elicitation, and other bioprocess methods. Furthermore, PCTOC-produced raw materials are free from contaminants, pesticides, and heavy metals and an important benefit of producing biomass in vitro is that it is easily accepted by regulatory authorities and consumers. In the current review, we describe the bioactive compounds of ginseng, purple coneflower, He-shou-wu, and St. John's wort which have cosmetological importance. Additionally, we elucidate the PCTOC method adopted for the production of biomass and bioactive compounds in these plants. 2023 SAAB -
Bioreactor configurations for adventitious root culture: recent advances toward the commercial production of specialized metabolites
In vitro plant cell and organ cultures are appealing alternatives to traditional methods of producing valuable specialized metabolites for use as: pharmaceuticals, food additives, cosmetics, perfumes, and agricultural chemicals. Cell cultures have been adopted for the production of specialized metabolites in certain plants. However, in certain other systems, adventitious roots are superior to cell suspension cultures as they are organized structures that accumulate high levels of specialized metabolites. The cultivation of adventitious roots has been investigated in various bioreactor systems, including: mechanically agitated, pneumatically agitated, and modified bioreactors. The main relevance and importance of this work are to develop a long-lasting industrial biotechnological technology as well as to improve the synthesis of these metabolites from the plant in vitro systems. These challenges are exacerbated by: the peculiarities of plant cell metabolism, the complexity of specialized metabolite pathways, the proper selection of bioreactor systems, and bioprocess optimization. This reviews major objective is to analyze several bioreactor types for the development of adventitious roots, as well as the advantages and disadvantages of each type of bioreactor, and to describe the strategies used to increase the synthesis of specialized metabolites. This review also emphasizes current advancements in the field, and successful instances of scaled-up cultures and the generation of specialized metabolites for commercial purposes are also covered. 2023 Informa UK Limited, trading as Taylor & Francis Group. -
Bioreactor systems for micropropagation of plants: present scenario and future prospects
Plant micropropagation has been adapted in the fields of agriculture, horticulture, forestry, and other related fields for large-scale production of elite plants. The use of liquid media and adoption of bioreactors have escalated the production of healthy plants. Several liquid-phase, gas-phase, temporary immersion, and other modified bioreactors have been used for plant propagation. The design, principle, operational mode, merits, and demerits of various bioreactors used for the regeneration of propagules, such as bulblets, cormlets, rhizomes, microtubers, shoots (subsequent rooting), and somatic embryos, are discussed here. In addition, various parameters that affect plant regeneration are discussed with suitable examples. Copyright 2023 Murthy, Joseph, Paek and Park. -
Anthraquinone Production from Cell and Organ Cultures of Rubia Species: An Overview
The Rubia genus includes major groups of medicinal plants such as Rubia cordifolia, Rubia tinctorum, and Rubia akane. They contain anthraquinones (AQs), particularly alizarin and purpurin, which have pharmacological effects that are anti-inflammatory, antioxidant, anticancer, hemostatic, antibacterial, and more. Alizarin and purpurin have been utilized as natural dyes for cotton, silk, and wool fabrics since the dawn of time. These substances have been used in the cosmetics and food industries to color products. The amount of AQs in different Rubia species is minimal. In order to produce these compounds, researchers have established cell and organ cultures. Investigations have been conducted into numerous chemical and physical parameters that affect the biomass and accumulation of secondary metabolites in a cell, callus, hairy root, and adventitious root suspension cultures. This article offers numerous techniques and approaches used to produce biomass and secondary metabolites from the Rubia species. Additionally, it has been emphasized that cells can be grown in bioreactor cultures to produce AQs. 2022 by the authors. -
Production of anthraquinones from cell and organ cultures of Morinda species
Abstract: Since ancient times, Morinda species, particularly Morinda citrifolia, have been used for their therapeutic benefits. Iridoids, anthraquinones, coumarins, flavonoids, lignans, phytosterols, and carotenoids are examples of natural substances with bioactivity. Anthraquinone derivatives are the most significant of these chemicals since they are utilized as natural coloring agents and have a wide range of medicinal functions. Utilizing cell and organ cultures of Morinda species, various biotechnological methods have been developed for the bioproduction of anthraquinone derivatives. The generation of anthraquinone derivatives in cell and organ cultures is summarized in this article. The methods used to produce these chemicals in bioreactor cultures have also been examined. Key points: This review investigates the potential of cell and organ cultures for anthraquinone synthesis. The overproduction of anthraquinones has been addressed using a variety of techniques. The use of bioreactor technologies for anthraquinone manufacturing is highlighted. 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. -
Nutritional Value, Fatty Acid and Phytochemical Composition, and Antioxidant Properties of Mysore Fig (Ficus drupacea Thunb.) Fruits
Ficus drupacea is a fruit-bearing tree that is distributed in Southeast Asia and Australia. The objective of this research was to ascertain the following with regard to ripened fruits: (i) their nutritional value, (ii) their mineral status, (iii) the fatty acid composition of fruit and seed oil, (iv) their phytochemical makeup, and (v) their antioxidant properties. The ripened fruits contained 3.21%, 3.25%, 0.92%, 1.47%, and 2.20% carbohydrate, protein, fat, ash, and fiber, respectively. Fruits had an energy content of 30.18 kcal/100 g. In terms of mineral content, the fruit was rich in potassium, magnesium, calcium, and nitrogen, with values of 21.03, 13.24, 11.07, and 4.13 mg/g DW. Iron, zinc, manganese, and boron had values of 686.67, 124.33, 114.40, and 35.78 g/g DW, respectively. The contents of oxalate and phytate were 14.44 and 2.8 mg/g FW, respectively. The fruit and seed oil content were 0.67 and 8.07%, respectively, and the oils physicochemical properties were comparable to those of fig fruit and seed oils. Omega-3 (?-linolenic acid), omega-6 (linoleic acid), and omega-9 (oleic acid) fatty acids were abundant in the oils. Fruit extracts in acetone, methanol, and water have greater concentrations of phenolics, flavonoids, and alkaloids. The 2,2-diphenyl-2-picrylhydrazyl, total antioxidant activity, and ferric reducing antioxidant power assays demonstrated increased antioxidant activities in close correlation with the higher concentrations of phenolics, flavonoids, and alkaloids. The results of this study demonstrate that the fruits of F. drupacea are a strong source of nutrients and phytochemicals, and they merit more investigation and thought for possible uses. 2024 by the authors. -
JUDE: An Ultraviolet Imaging Telescope pipeline
The Ultraviolet Imaging Telescope (UVIT) was launched as part of the multi-wavelength Indian AstroSat mission on 28 September, 2015 into a low Earth orbit. A 6-month performance verification (PV) phase ended in March 2016, and the instrument is now in the general observing phase. UVIT operates in three channels: visible, near-ultraviolet (NUV) and far-ultraviolet (FUV), each with a choice of broad and narrow band filters, and has NUV and FUV gratings for low-resolution spectroscopy. We have written a software package (JUDE) to convert the Level 1 data from UVIT into scientifically useful photon lists and images. The routines are written in the GNU Data Language (GDL) and are compatible with the IDL software package. We use these programs in our own scientific work, and will continue to update the programs as we gain better understanding of the UVIT instrument and its performance. We have released JUDE under an Apache License. 2017 Elsevier B.V. -
Fusion of medical image using STSVD
The process of uniting medical images which are taken from different types of images to make them as one image is a Medical Image Fusion. This is performed to increase the image information content and also to reduce the randomness and redundancy which is used for clinical applicability. In this paper a new method called Shearlet Transform (ST) is applied on image by using the Singular Value Decomposition (SVD) to improve the information content of the images. Here two different images Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) are taken for fusing. Initially the ST is applied on the two input images, then for low frequency coefficients the SVD method is applied for fusing purpose and for high frequency coefficients different method is applied. Then fuse the low and high frequency coefficients. Then the Inverse Shearlet Transform (IST) is applied to rebuild the fused image. To carry out the experiments three benchmark images are used and are compared with the progressive techniques. The results show that the proposed method exceeds many progressive techniques. Springer Nature Singapore Pte Ltd. 2017. -
Progress in psycho-oncology with special reference to developing countries
Purpose of reviewPsycho-oncology has completed 25 years. There is growing recognition of the psychosocial needs of persons living with cancer and the role of sociocultural factors in addressing the needs. This review addresses the research in developing countries relating to distress associated with living with cancer and psychosocial care.Recent findingsThere is growing recognition of the emotional needs, understanding of the sociocultural aspects of the emotional responses of persons, caregivers, role of resilience and posttraumatic growth and spirituality in cancer care. Psychosocial aspects of cancer are largely influenced by social, economic, cultural, religious and health systems. A number of innovative approaches to care like use of yoga, financial and material support and involvement of caregivers have been implemented. A positive development is the increasing professional attention to document and develop innovative care programmes.SummaryA significant proportion of the general population are living with cancer. There are significant psychosocial needs largely influenced by social, economic, cultural, religious aspects of the communities. There are a wide range of interventions from self-care to professional care to address the needs. In developing countries, there is need for longitudinal studies of psycho-social experiences, develop interventions that are culturally appropriate, along with enhanced use of information technology along with evaluation of interventions. 2019 Wolters Kluwer Health, Inc. All rights reserved. -
Prob(E)abilities for enhanced research and interdisciplinarity: An exploration of innovative practices in english studies, languages, and media
An analysis of the history of research as well as contemporary trends in higher education in India reveals the predominance of scientific research. Public policies, developmental strategies, and market forces often determine the nature and output of research in humanities and social sciences. Research in literatures, languages, and media needs articulationa process that reveals the significant interdisciplinary interventions that can be brought to the process of research and highlights the need for purpose-driven research as research rather than need-based research for research. This paper offers a critical overview of the role of research in universities in India, contemporary approaches to research at the national level, and the need to engage in interdisciplinary, collaborative, and action-based research, especially in humanities and social sciences departments in universities across India. Further, the paper offers a few examples of interdisciplinary and collaborative research to highlight the need for a symbiotic approach to academic research. 2020 IUP. All Rights Reserved. -
Amberlite-15 promoted an unprecedented aza Michael rearrangement for one pot synthesis of dihydroquinazolinone compounds
A new one pot multicomponent annulation strategy for the synthesis of various dihydroquinazolinone compounds has been developed using Amberlite-15 as a catalyst, giving good to moderate yields. In this reaction the substrate scope for amines and aldehydes was also investigated. The reaction has been checked on a large scale and the possible reaction mechanism has also been proposed. The Royal Society of Chemistry 2018. -
Multifunctional Inorganic Nanomaterials: Synthesis, Properties, and Applications
Multifunctional Inorganic Nanomaterials: Synthesis, Properties, and Applications focuses on the latest discoveries and advances in the field of inorganic nanomaterials dealing with synthesis, functionalization, morphology, and physio-chemical properties of 1D, 2D, and 3D advanced materials and their interdisciplinary applications. This book reveals the significance of understanding the synthesis methodologies in tuning the nano-size properties of inorganic materials using various parameters to functionalize to specific applications in a variety of sectors covering energy, environment, and health. 2026 selection and editorial matter, H. C. Ananda Murthy, Velumani Subramaniam, Mika Sillanp, R. Balachandran, and Gurumurthy Hegde; individual chapters, the contributors. -
Future Perspectives of Microplastic towards Environmental Assessment
Microplastic (MP) pollution is an outcome of the widespread use of non-biodegradable plastic and improper disposal. This leads to contamination of environmental resources, such as landfills, and all kinds of water reservoirs including but not limited to sea, fresh water, drinking water, and even wastewater. Recent reports have highlighted the presence of MPs in the human body, including blood, lungs, placentas, and breast milk, indicating the severity of the issue. It is thus crucial to eliminate these hazardous contaminants from the environment. One of the effective methods to address the concern while reducing the adverse effects is to remove the MPs at their discharge points. Nanomaterials with exceptional properties like high surface area, ease of functionalization, and high affinity toward various pollutants act as excellent adsorbents. In this chapter, we present an overview of emerging nanomaterial-based adsorbents, such as photocatalysts, metal-organic frameworks, carbon-based nanomaterials, and nanocomposites, for effective removal of MPs from aqueous media via adsorption, photo-catalysis, and membrane filtration. However, considering that the research in the area of MP pollution is still in its infant stage, we aim to provide a brief account of the strengths, weaknesses, and future research dimensions of nanomaterial-based adsorbents for removing MPs from aqueous media. 2025 selection and editorial matter, Nirmala Kumari Jangid and Rekha Sharma; individual chapters, the contributors. -
Augmented and Virtual Reality in Immersive Healthcare
Future-proof your medical expertise with this indispensable guide that offers a comprehensive, expert-led exploration of how Augmented and Virtual Reality (AR/VR) are revolutionizing healthcare. Augmented reality (AR) and virtual reality (VR) have profoundly impacted the healthcare sector, introducing ground-breaking applications ranging from surgical simulations and pain management to mental health therapies and patient education. This book delves into the various applications of AR and VR, including deep learning, surgical training, teleconsultation, and patient rehabilitation. By blending theoretical insights with practical case studies, it provides a deeper understanding of how these technologies are being integrated into medical practices to improve outcomes, enhance patient care, and train healthcare professionals. It also explores cutting-edge developments, such as AI-powered AR systems and VR-based mental health treatments, highlighting the future of healthcare innovation. With contributions from leading experts in healthcare, technology, and academia, this book offers a multidimensional perspective on the challenges and opportunities associated with AR and VR in the medical field. Through its accessible language and detailed illustrations, this book is an indispensable guide for anyone interested in the intersection of technology and medicine. Readers will find the volume: Provides a comprehensive exploration of how immersive technology is unlocking new possibilities in healthcare, education, and rehabilitation; Offers insights from top researchers and practitioners in the field, providing authoritative perspectives on the latest technologies, applications, and trends shaping the future of XR; Offers practical guidance and actionable insights to help you harness the power of AR and VR, accelerating innovation and driving real-world impacts; Uncovers the diverse range of applications empowered by the convergence of healthcare and gamification, revolutionizing healthcare delivery and improving patient outcomes. Audience Healthcare professionals, medical educators and students, engineers, developers, researchers, and policymakers looking for cutting-edge technologies to enhance patient care and treatment outcomes. 2026 Scrivener Publishing LLC. -
Bioactive Compounds in Edible Flowers
Many societies have found various utilities of edible flowers. They give a more ornamental look, enhances the taste, and also enhances its nutritional value. Numerous studies conducted recently have shown that edible flowers are also rich in nutrients such as carbohydrates, proteins, fats, fibre, vitamins, minerals. These flowers also contain a variety of phytochemicals, including phenolics, flavonoids, carotenoids, terpenoids, alkaloids, and other compounds that have been shown to increase biological activities, such as antioxidant, antimicrobial and antidiabetic, anticancer, cardioprotective, hepatoprotective, and neuroprotective qualities. Edible flowers have now found their way into a number of industries, including as cosmeceuticals, functional foods, and nutraceuticals. The book provides information on the nutritional value, phytochemical makeup, and bioactivity of both wild and cultivated flowers. It also describes edible flowers in depth to make them better-known to consumers and the food business. Each chapter discusses the possible toxicological effects of floral components. 2026 Hosakatte Niranjana Murthy.