Therapeutic effects of vitamin D and cancer: An overview
- Title
- Therapeutic effects of vitamin D and cancer: An overview
- Creator
- Varghese J.E.; Balasubramanian B.; Velayuthaprabhu S.; Thirunavukkarasu V.; Rengarajan R.L.; Murugesh E.; Manikandan P.; Arun M.; Anand A.V.
- Description
- Since vitamin D's discovery, strenuous efforts to investigate its physiological exploit and deficiency on human health were done. Our body synthesizes fat-soluble vitamin D when get exposed to sunlight. In recent years, experimental data indicate that sunlight exposure and an adequate level of circulating vitamin D can reduce the incidence of cancer. Several in vitro and in vivo studies also suggest vitamin D as a potentially valuable supplement for cancer treatment and prevention. Nevertheless, there need to be adequate clinical studies performed to substantiate the suppressive ability of vitamin D concerning cancer incidence. Thus, understanding the cellular mechanisms of vitamin D can be advantageous for preventing several chronic diseases. Consequently, this review concentrates on different studies that have been conducted to characterize the outcome of vitamin D in reducing cancer incidence and its medication by cellular progression mechanism. 2021 The Authors. Food Frontiers published by John Wiley & Sons Australia, Ltd and Nanchang University, Northwest University, Jiangsu University, Zhejiang University, Fujian Agriculture and Forestry University.
- Source
- Food Frontiers, Vol-2, No. 4, pp. 417-425.
- Date
- 2021-01-01
- Publisher
- John Wiley and Sons Inc
- Subject
- calcitriol; cancer; cholecalciferol; single nucleotide polymorphism; vitamin D
- Coverage
- Varghese J.E., Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, India; Balasubramanian B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, South Korea; Velayuthaprabhu S., Department of Biotechnology, Bharathiar University, Tamil Nadu, India; Thirunavukkarasu V., Department of Biotechnology, Bharathiar University, Tamil Nadu, India; Rengarajan R.L., Department of Animal Science, Bharathidasan University, Tamil Nadu, India; Murugesh E., Nutritional Improvement of Crops, International Centre for Genetic Engineering and Biotechnology, New Delhi, India; Manikandan P., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, India; Arun M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, India; Anand A.V., Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, India
- Rights
- Restricted Access
- Relation
- ISSN: 26438429
- Format
- Online
- Language
- English
- Type
- Review
Collection
Citation
Varghese J.E.; Balasubramanian B.; Velayuthaprabhu S.; Thirunavukkarasu V.; Rengarajan R.L.; Murugesh E.; Manikandan P.; Arun M.; Anand A.V., “Therapeutic effects of vitamin D and cancer: An overview,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 23, 2025, https://archives.christuniversity.in/items/show/21566.