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Eye-Tracking Measures in Aviation: A Selective Literature Review
Objective: The aim of this article is to present a comprehensive review of eye-tracking measures and discuss different application areas of the method of eye tracking in the field of aviation. Background: Psychophysiological measures such as eye tracking in pilots are useful for detecting fatigue or high-workload conditions, for investigating motion sickness and hypoxia, or for assessing display improvements and expertise. Method: We review the uses of eye tracking on pilots and include eye-tracking studies published in aviation journals, with both a historical and contemporary view. We include 79 papers and assign the results to the following three categories: Human performance, aircraft design, health and physiological factors affecting performance. We then summarize the different uses of eye tracking in each category and highlight metrics which turned out to be useful in each area. Our review is complementary to that of Ziv (2016). Results: On the basis of these analyses, we propose useful application areas for the measurement of eye tracking. Eye tracking has the potential to be effective in terms of preventing errors or injuries by detecting, for example, fatigue or performance decrements. Applied in an appropriate manner in simulated or real flight it can help to ensure optimal functioning of manmachine systems. Conclusion: Further aviation psychology and aerospace medicine research will benefit from measurement of eye movements. 2018, 2018 The Author(s). Published with license by Taylor and Francis Group, LLC. -
The Role of the Gut Microbiota in Neurodegenerative Diseases
The human gut has a rich and dynamic microbial population that plays an important role in many physiological activities. This review explores the complex interaction between the gut microbiota and human health, with an emphasis on its effect on neurodegenerative illnesses. The makeup of the gut microbiome and its impact on brain function through the gutbrain axis is highlighted. Dysbiosis, characterized by changes in the gut microbiotas composition, has been linked to the development of neurodegenerative diseases such as Alzheimers, Parkinsons, Huntingtons, and amyotrophic lateral sclerosis. A Bidirectional communication between the stomach and the brain takes place via a variety of channels, including neurotransmitters and metabolites generated by gut bacteria. We investigate the processes through which dysbiosis causes neuroinflammation, oxidative stress, and neuronal damage, which drive disease development. Potential therapeutic approaches that focus on the gut microbiota, such as antibiotics, probiotics, prebiotics, and fecal microbiota transplantation, are reviewed, with promising preclinical and clinical findings. Overall, this study emphasizes the relevance of gut microbiota to neurodegenerative illnesses, as well as the need to understand and target the gut-brain axis for future treatment options. 2024 by the authors. -
A survey of the studies on Gallai and anti-Gallai graphs
The Gallai graph and the anti-Gallai graph of a graph G are edge disjoint spanning subgraphs of the line graph L(G). The vertices in the Gallai graph are adjacent if two of the end vertices of the corresponding edges in G coincide and the other two end vertices are nonadjacent in G. The anti-Gallai graph of G is the complement of its Gallai graph in L(G). Attributed to Gallai (1967), the study of these graphs got prominence with the work of Sun (1991) and Le (1996). This is a survey of the studies conducted so far on Gallai and anti-Gallai of graphs and their associated properties. 2021 Azarbaijan Shahid Madani University. -
Influence of career re-entry enablers on job search outcomes: COVID strengthening the disparity virus?
Women in India when faced with the predicament of managing their homes and work, many a times are forced to take a break from their job. On completion of their personal responsibilities when they contemplate re-entering work, they face numerous hindrances. Covid has only raised additional concerns in their career landscape. In this context based on the social cognitive career theory that adopts human agency perspective we theorize that women are not mere bystanders but themselves contribute to their life outcomes through their self-efficacy and resultant job search efforts. Using the components in the SCCT model (Social cognitive career theory) of career self-management (CSM), data from 385 respondents was analysed using Exploratory Factor Analysis, Confirmatory Factor Analysis and Structure Equation Modeling. The study confirmed the direct and indirect relationship between self-efficacy in job search behaviour, outcome expectations, search goals, search actions and the final job search outcome measured through the number of offers received. Implications of this study to the managers, family and society are also discussed. 2021 Ecological Society of India. All rights reserved. -
Study of the personal factors influencing voluntary turnover amongst women
In a country where the economic and social independence of a woman is dependent on the way households are structured and organised, the rise in their education and decline in their workforce participation rate is an indication of their paradoxical situation. In this study we evaluate the direct effect of the factors in the personal domain of women on her career break decision. The data from 402 Indian women was analysed using Exploratory Factor Analysis and Confirmatory Factor Analysis, which was then followed by Structural Equation Modelling to check the conceptual model developed through literature review. In present study support personal predictors to turnover intention outcome model, confirming the influence of role conflict, role expectation, role perception, stress, financial soundness, role overload and guilt. Role perception and expectation of women were most significant factors influencing turnover intention of women, implying that the most important change needed is for a change in their own mindset and those around them to arrest their exit from the workforce. 2021 Ecological Society of India. All rights reserved. -
Exploring the far-reaching consequences of malnutrition during pregnancy and beyond: A comprehensive review
In India, maternal and infant malnutrition continues to be a significant contributor to health problems. Fetal malnutrition can result from an inadequate nutrient supply, necessary nutrition services, and ideal practices before, during, and following pregnancy. This comprehensive review delves into the complex relationships among hormone changes, microbial ecosystems, and nutrition, and how these relationships affect the health of mothers and their offspring. The review highlights how important it is to maintain good nutrition during pregnancy and to comprehend the dietary modifications that pregnant people make on their own to create interventions that work. Important minerals like calcium, iron, folic acid, iodine, and vitamin D are covered. Acknowledging the mutualistic association between the eating habits of mothers and the diverse microbiomes found in their gut, vagina, and oral channels, the review explores the influence on hormone levels and their consequences during gestation. Diverse fetal developmental needs are depicted by the table that outlines food requirements for each of the three trimesters. The detrimental effects of poor prenatal nutrition on a mothers health and its repercussions for neonates are examined. The effects of malnutrition after delivery, including difficulties throughout pregnancy, healing periods, and general effects on mental and physical health, are well studied. The study, which adopts a worldwide viewpoint, finds that societal norms, information gaps, and poverty are the main causes of malnutrition. Prevention techniques are discussed, emphasizing the significance of taking a comprehensive approach to addressing this vital issue in both the Indian and global contexts. 2024 Visagaa Publishing House. -
X-Ray and ?-Ray Shielding Efficiency of Polymer Composites: Choice of Fillers, Effect of Loading and Filler Size, Photon Energy and Multifunctionality
Use of X-rays and ?-rays have become inevitable in medical sectors like radiology, interventional cardiology and diagnostic imaging, radiation physics laboratories, nuclear reactors and accelerator facilities. As radiation exposures above permitted levels pose potential risk to personnel working in close proximity to these facilities, protective measures aimed at reducing the exposure for safeguarding against harmful effects of ionizing radiations are essential. Traditionally, lead and lead based materials have been used as efficient radiation shielding materials owing to the high atomic number and high density of lead. Presently, use of lead is discouraged due to its heavy weight, toxicity and long-term effects on the environment. Consequently, the last two decades have seen research on light weight and cost-effective polymer composites with appropriate additives, having good workability, high specific strength, thermo-chemical stability and radiation shielding efficacy, gaining momentum. This article gives an overview of the state-of-the-art polymer composites reinforced with different fillers studied for their use as effective radiation shields. Here, we summarize the recent advancement and current trends in polymer composites-based radiation shields highlighting the different approaches adopted, choice of polymer/fillers, shielding effectiveness in terms of either linear and/or mass attenuation coefficients, for those who venture into radiation research and development. 2022 Taylor & Francis Group, LLC. -
2,2,6,6-Tetramethylpiperidinyloxyl (TEMPO) Radical Mediated Electro-Oxidation Reactions: A Review
Over the last few decades, the interest in green and sustainable chemistry has led to the development of different synthetic methodologies which utilize clean reagents. In that direction, the electro-oxidation reactions are considered as one of the most interesting and promising methods. This is predominantly due to their environmentally benign nature, as oxidation can be achieved without the need for commonly used oxidizing agents. 2,2,6,6-Tetramethylpiperidinyloxyl radical commonly known as TEMPO is a stable aminoxyl radical utilized for the oxidation of various classes of alcohols to carbonyl compounds by using cyclic voltammetry. The present review focuses on the various electrochemical reactions utilizing TEMPO as a mediator such as the oxidative conversion of alcohols, carbohydrates, amines, sulphur-containing compounds, and alkenes in both laboratory as well as industrial scales and covers literature from 1950 till present date. The properties, reactivity, and yield percentages of these reactions would provide a basis for better electrocatalyst design in future studies involving TEMPO and its derivatives as mediators. 2021 Wiley-VCH GmbH -
Is robotics education and training gender dependent? A suggestive robotics syllabus for teacher training
Application of robotics is rapidly increasing in all fields of life. Though robotics education became popular in the 21st century, its teaching and training has not gained much importance across the world, especially in developing and low-income countries. There are various reasons for its neglect and one of them could be gender-science stereotypes. Research studies are yet to explore the reasons for its slow emergence. The present study explores the need and training for educational robotics considering the role of students, teachers, teacher-educators and parents, determining whether it is gender-dependent or not. The study also proposes to come up with a syllabus for robotics training. The study employs exploratory, sequential, qualitative-quantitative mixed-method research design and applies purposive sampling techniques. Researchers conducted semi-structured interviews, including five science teacher-educators, five science teachers, and five trainee teachers majoring in sciences to understand the need, scope and benefits of robotics education. They recruited 100 high school students, 50 teacher-educators, and 100 parents to test whether their interest in robotics is gender-dependent through Chi-square analysis. The study revealed the need for robotics education under four themes and seven subthemes. It has been found that the interest of students and parents and the readiness of teacher-educators for robotics education is gender-dependent. The study came up with a suggestive syllabus for robotics training. It recommends that future researchers should focus on the implementation of robotics teaching for teacher and school education. 2021 Authors. -
Diazanorbornene: A Valuable Synthon towards Carbocycles and Heterocycles
Desymmetrization of meso compounds is well recognized as a powerful method for delivering biologically relevant molecular skeletons in a few synthetic steps. Heterobicyclic olefins are a class of meso compounds which exhibit exceptional reactivity due to their high ring strain originating from the unfavorable bond angles and eclipsing interactions. Extensive research was carried out towards the synthetic transformations of oxa-, aza-, and diazanorbornenes/norbornadienes for the synthesis of a wide variety of carbocycles and heterocycles in a single step, most importantly in a stereo- and chemo-selective manner. This review summarizes the relevant aspects of diazanorbornene reactivity which will inspire the synthetic community for exploiting these highly strained bicyclic systems for the creation of extensive libraries of novel structurally and biologically interesting molecules. The review is divided into several sections based on the type of reactions that diazanorbornenes are subjected to. 2020 Wiley-VCH GmbH -
Discovering Consumer Behavior Towards Back-of-Pack Nutrition Labels: A Systematic Literature Review
This systematic literature review aims to examine the impact of back-of-pack (BOP) labels on food manufacturers' practices in the field of consumer behaviour research. The review comprehensively analyses a wide range of articles spanning over two decades to provide an up-to-date and comprehensive analysis of the subject matter. It focuses specifically on how BOP labels affect consumers, food manufacturers' behaviors and practices. The findings highlight that BOP labels conveying intuitive information effectively prompt product reformulation, particularly in reducing unhealthy nutrients such as sodium, sugar, and calories. Voluntary BOP labeling has limited uptake and is often applied to already healthier products. Consumers and food producers' response varies based on label design and enforcement type, suggesting strategic labeling of healthier choices. The review provides valuable insights for future public health research and policymaking efforts, emphasizing the importance of mandatory policies and specific guidance in BOP labels. This research brings novelty by comprehensively examining the impact of back-of-pack (BOP) labeling on consumers and food manufacturers' practices. The findings contribute to the literature by highlighting the differential effects of mandatory and voluntary BOP labeling approaches and offering insights into label design and enforcement types. As per the researcher knowledge there is no available systematic literature review (SLR) specifically focusing on BOP labeling in recent years. Future research should explore the long-term impacts of mandatory versus voluntary BOP labeling on consumer dietary habits and food manufacturers' product reformulation strategies. 2024 The Author(s). -
Advancements in Sustainable Techniques for Dried Meat Production: an Updated Review
Dried meat is one of the ethnic and aesthetic food products popular among global civilizations and communities. The background of the production is associated with several methods practiced conventionally in the olden days. This review focused on investigating the advantages, challenges, research gaps, and technological intervention in dried meat production in the modern era. Moreover, it presented a gestalt of cutting-edge thermal and non-thermal food processing technologies and their effectiveness in extending shelf life. It delved into the specific characteristics of dried meat, including biochemical, sensory, and microbiological properties and processing techniques, and addressed the contamination sources. The pros and cons of various drying methods like hot-air drying, vacuum pulsed electric field, microwave-assisted techniques, and non-thermal drying processes are comprehended. The impact on meat's structural properties, nutritional value, shelf-life, quality control, and food safety are thoroughly presented. Moreover, the review explored the biochemical dynamics of the drying process and underscored the health risks associated with mycotoxin contamination in dried meat products. Furthermore, the study also presented the avenues of AI-based platforms and non-destructive technology for validating the quality of dried meat products. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. -
Out of Box Thinking to Tangible Science: A Benchmark History of 3D Bio-Printing in Regenerative Medicine and Tissues Engineering
Advancements and developments in the 3D bioprinting have been promising and have met the needs of organ transplantation. Current improvements in tissue engineering constructs have enhanced their applications in regenerative medicines and other medical fields. The synergistic effects of 3D bioprinting have brought technologies such as tissue engineering, microfluidics, integrated tissue organ printing, in vivo bioprinted tissue implants, artificial intelligence and machine learning approaches together. These have greatly impacted interventions in medical fields, such as medical implants, multi-organ-on-chip models, prosthetics, drug testing tissue constructs and much more. This technological leap has offered promising personalized solutions for patients with chronic diseases, and neurodegenerative disorders, and who have been in severe accidents. This review discussed the various standing printing methods, such as inkjet, extrusion, laser-assisted, digital light processing, and stereolithographic 3D bioprinter models, adopted for tissue constructs. Additionally, the properties of natural, synthetic, cell-laden, dECM-based, short peptides, nanocomposite and bioactive bioinks are briefly discussed. Sequels of several tissue-laden constructs such as skin, bone and cartilage, liver, kidney, smooth muscles, cardiac and neural tissues are briefly analyzed. Challenges, future perspectives and the impact of microfluidics in resolving the limitations in the field, along with 3D bioprinting, are discussed. Certainly, a technology gap still exists in the scaling up, industrialization and commercialization of this technology for the benefit of stakeholders. 2023 by the authors. -
Mucormycosis (black fungus) ensuing COVID-19 and comorbidity meets - Magnifying global pandemic grieve and catastrophe begins
Post COVID-19, mucormycosis occurred after the SARS-CoV-2 has rampaged the human population and is a scorching problem among the pandemic globally, particularly among Asian countries. Invasive mucormycosis has been extensively reported from mild to severe COVID-19 survivors. The robust predisposing factor seems to be uncontrolled diabetes mellitus, comorbidity and immunosuppression acquired through steroid therapy. The prime susceptive reason for the increase of mucormycosis cases is elevated iron levels in the serum of the COVID survivors. A panoramic understanding of the infection has been elucidated based on clinical manifestation, genetic and non- genetic mechanisms of steroid drug administration, biochemical pathways and immune modulated receptor associations. This review lime-lights and addresses the What, Why, How and When about the COVID-19 associated mucormycosis (CAM) in a comprehensive manner with a pure intention to bring about awareness to the common public as the cases are inevitably and exponentially increasing in India and global countries as well. The article also unearthed the pathogenesis of mucormycosis and its association with the COVID-19 sequela, the plausible routes of entry, diagnosis and counter remedies to keep the infection at bay. Cohorts of case reports were analysed to spotlight the link between the pandemic COVID-19 and the nightmare-mucormycosis. 2021 Elsevier B.V. -
The crux of bioactive metabolites in endophytic and thermophilic fungi and their proximal prospects in biotechnological and industrial domains
Fungi are ubiquitous in distribution and are found in grasses to hot springs. Their mode of nutrition provides sustenance for living and propagation. Ironically, varied fungal species have developed customized strategies for protection and survival by producing diverse secondary metabolites. The review aimed to project the contrasting potential features of the endophytic and thermophilic fungi groups. The metabolites and the enzymes of endophytic and thermophilic fungi served as the backbone to thrive and adapt within-host and in extreme conditions like higher pH, heat, and salinity, respectively. Identification, knowledge of their biochemistry and pathway, exploration, production, and utilization of these bioactive molecules in various commercial, industrial, and pharmaceutical domains were briefly discussed. The uniqueness of endophytes includes stress management and improved biomass production of the host, green fuel production, omnipresence, selected triple-symbiosis with the virus, synthesis of polyketides, and other active metabolites are widely used in biomedical applications and agriculture management. This review attempted to limelight the specific applications of thermophilic fungal metabolites and the roles of thermo-stable enzymes in bioprospecting. Moreover, probing the metabolites of thermophiles rendered novel antibiotic compounds, which were proven effective against multi-drug resistant bacteria and harboured the potential to curtail infectious diseases. 2022 Elsevier Ltd -
Occurrence, identification, and decontamination of potential mycotoxins in fruits and fruit by-products
The incidence of aflatoxins, ochratoxin A, and patulin in fruits and processed fruit products has been ever more challenging and gained additional focus on ecofriendly mitigation strategies. The onset of these toxins is due to several factors involving insect attacks, agricultural practices, and climate change. Acute and chronic health hazards are clinically proven after consuming contaminated foodstuffs, even at lower concentrations of mycotoxins. Synergistic, masked, and substantial occurrence in fruit matrices increase their complexity in detection and detoxification; apparently, this article reviewed the available information on the occurrence of mycotoxins in several fruits and their products, focused on the conventional and advanced methods of identification, quantification, and decontamination techniques. Strengthening and implementing stringent international and national guidelines are required for impactful, tangible measures in the future. Nevertheless, controlling the mycotoxins in fruits will certainly be challenging for scientists. Therefore, more impactful technologies are still needed to eliminate the toxins at the threshold level of the food chain and ensure sustainable global food safety. 2023 The Authors. Food Frontiers published by John Wiley & Sons Australia, Ltd and Nanchang University, Northwest University, Jiangsu University, Zhejiang University, Fujian Agriculture and Forestry University. -
Potential of insect-based milk moiety from Pacific beetle cockroach, Diploptera punctata (Blattodea): Insights as superfood
Diploptera punctata is a viviparous cockroach and secretes a concoction of glycosylated proteins as a basis of nutrition for developing embryos termed as cockroach milk. The milk proteins were identified as the lipocalin-like milk proteins (Lili-Mip) which are present in the brood sac of the gestated female D. punctata. Blotting techniques and RNA transcriptome assays have reported analogous Lili-Mip in the midgut of D. puncta embryos, which proved the ingestion during development inside brood sac. Thermodynamics and kinetic studies augmented the stability of the milk crystals and their controlled release mechanism of sustenance. Gene ontogeny reported the evolution of the ovoviviparous to viviparous due to selective pressures posed during the development stages of the embryos. Molecular simulation modelling studied unveiled the binding efficacies of the milk protein to build strong affiliates to the ligands to form a stable milk protein complex. Ahead of its nutritional benefits, cockroach milk also offers environmental advantages compared to traditional dairy and plant-based milk production. Nevertheless, there are still important hurdles to overcome to include this unconventional superfood as staple in human diets which are also discussed in the review. This review explored the existing molecular, evolutionary and biochemical insights for understanding the phenomena of the production of milk crystals and addressed the research gaps for developing a novel nutrient prospective from insect source. 2024 Korean Society of Applied Entomology -
Emerging Nanoparticle-Based Diagnostics and Therapeutics for Cancer: Innovations and Challenges
Malignant growth is expected to surpass other significant causes of death as one of the top reasons for dismalness and mortality worldwide. According to a World Health Organization (WHO) study, this illness causes approximately between 9 and 10 million instances of deaths annually. Chemotherapy, radiation, and surgery are the three main methods of treating cancer. These methods seek to completely eradicate all cancer cells while having the fewest possible unintended impacts on healthy cell types. Owing to the lack of target selectivity, the majority of medications have substantial side effects. On the other hand, nanomaterials have transformed the identification, diagnosis, and management of cancer. Nanostructures with biomimetic properties have been grown as of late, fully intent on observing and treating the sickness. These nanostructures are expected to be consumed by growth in areas with profound disease. Furthermore, because of their extraordinary physicochemical properties, which incorporate nanoscale aspects, a more prominent surface region, explicit geometrical features, and the ability to embody different substances within or on their outside surfaces, nanostructures are remarkable nano-vehicles for conveying restorative specialists to their designated regions. This review discusses recent developments in nanostructured materials such as graphene, dendrimers, cell-penetrating peptide nanoparticles, nanoliposomes, lipid nanoparticles, magnetic nanoparticles, and nano-omics in the diagnosis and management of cancer. 2025 by the authors. -
The shadow of truth: Ethical Concerns in the Writings of Alexander Solzhenitsyn
"One word of truth will outweigh the entire world." These were the words of Alexander Solzhenitsyn while accepting the Nobel Prize in 1974. The twentieth century was the bloodiest century in human history, thanks largely to two ideologies - Fascism and Marxism. While there have been numerous studies on Nazi Germany, there have been relatively few on what transpired in Soviet Russia. This paper examines the contributions of the Russian writer and philosopher Alexander Solzhenitsyn to the understanding of the workings of totalitarianism. Solzhenitsyn wrote numerous works like The First Circle, Cancer Ward and The Gulag Archipalego. This paper will be examining his major work called One Day in the Life of Ivan Denisovich. The main intention is to probe the ethical concerns that the writer raises in this work, along with his deep understanding of human nature. This paper also seeks to compare Solzhenitsyn's views with that of thinkers like Jean Paul Sartre and Vaclav Havel. The key query here will be the essence-existence debate that Sartre initiated in his seminal work 'Existentialism Is a Humanism' and an attempt will be made to show how Havel and Solzhenitsyn would differ from Sartre. Finally there will be an attempt to establish how Solzhenitsyn reaffirms Lev Tolstoy's theory of history, according to which history is a process where 'great individuals' play a minimal role. 2013 Journal of Dharma: Dharmaram Journal of Religions and Philosophies (Dharmaram Vidya Kshetram, Bangalore). -
Dharma in Manusmrti: Agent of social cohesion and equilibrium
Dharma, through its role as a moral ideal and through its manifestations that permeate every part of the society, binds all the individuals in Manu's society as envisaged in Manusmrti. It serves as a common value and dictates common goals for the people that could be attained by functioning for the good of the institutions they belong to and, ultimately, for the survival of the society. Social institutions like marriage, family, varna system, as?rama system, political system and legal system were structured with accurate positions and roles for their efficient and smooth functioning. They were made to function compatibly with each other to ensure the survival of the society. Manu carefully avoided conflicts and competitions in the society. Thus, by acting as a cohesive agent, Dharma, as a foundational moral principle, integrates both individuals and the institutions to maintain the equilibrium of Manu's state. 2013 Journal of Dharma: Dharmaram Journal of Religions and Philosophies (Dharmaram Vidya Kshetram, Bangalore), ISSN: 0253-7222.