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The unique risk factor profile of triple-negative breast cancer: a comprehensive meta-analysis
Background: Triple-negative breast cancer (TNBC) has a poor prognosis compared with other breast cancer subtypes. This systematic review and meta-analysis examines whether known risk factors for breast cancer are also associated with TNBC in adult women. Methods: EMBASE, Medline, SCOPUS, and gray literature were queried with no limit on the date or language of publication. The exposures of interest included parity, breastfeeding, duration of breastfeeding, age at menarche, age at first live birth, oral contraceptive (OC) use, duration of OC use, use of menopausal hormone therapy (MHT), family history, body mass index (BMI), alcohol use, smoking, and breast density. The main outcome of interest was TNBC. Study quality was determined using the Newcastle-Ottawa scale for case control studies and cohort studies. We estimated weighted odds ratios from random effects models to study the exposureoutcome associations. Protocol was registered under the number: PROSPERO 2021 CRD42021254594. Results: Thirty-three studies were included. Family history, longer duration of OC use, and higher breast density were significantly associated with increased risk for TNBC, whereas later age at menarche, later age at first birth, and breastfeeding were protective against TNBC. Parity, MHT, alcohol, smoking, and BMI were not significantly associated with TNBC overall, but higher parity was associated with higher risk among Black women. Conclusion: Our findings highlight that TNBC has a distinct risk factor profile compared with overall breast cancer. This can be the foundational work in identification of actionable TNBC risk factors to improve prevention and early detection of these poor prognosis breast tumors. The Author(s) 2024. -
Discovering Consumer Behavior Towards Back-of-Pack Nutrition Labels: A Systematic Literature Review
This systematic literature review aims to examine the impact of back-of-pack (BOP) labels on food manufacturers' practices in the field of consumer behaviour research. The review comprehensively analyses a wide range of articles spanning over two decades to provide an up-to-date and comprehensive analysis of the subject matter. It focuses specifically on how BOP labels affect consumers, food manufacturers' behaviors and practices. The findings highlight that BOP labels conveying intuitive information effectively prompt product reformulation, particularly in reducing unhealthy nutrients such as sodium, sugar, and calories. Voluntary BOP labeling has limited uptake and is often applied to already healthier products. Consumers and food producers' response varies based on label design and enforcement type, suggesting strategic labeling of healthier choices. The review provides valuable insights for future public health research and policymaking efforts, emphasizing the importance of mandatory policies and specific guidance in BOP labels. This research brings novelty by comprehensively examining the impact of back-of-pack (BOP) labeling on consumers and food manufacturers' practices. The findings contribute to the literature by highlighting the differential effects of mandatory and voluntary BOP labeling approaches and offering insights into label design and enforcement types. As per the researcher knowledge there is no available systematic literature review (SLR) specifically focusing on BOP labeling in recent years. Future research should explore the long-term impacts of mandatory versus voluntary BOP labeling on consumer dietary habits and food manufacturers' product reformulation strategies. 2024 The Author(s). -
Epidemiological Transition in India and Determinants that Are Shifting Disease Burden: A Systematic Review
Indias disease burden patterns are shifting towards increased morbidity and mortality from Non-communicable disease and chronic diseases. This is one of the first studies conducted using the PRISMA guidelines and checklist to understand the role played by various determinants of health in this epidemiological transition happening in India. The search on 9 reputed bibliographic databases yielded 459 articles and finally 58 articles were selected based on carefully curated selection criteria. The results confirm the relation between India's demographic transition and the increasing disease burden from Non-communicable diseases (NCDs). 21 studies significantly associated urban residential status, increasing income, better living conditions and education with increasing NCDs' prevalence. 12 studies found that NCDs were more prevalent among women than men. Increased physical activity, a healthy diet and a lower hipto-waist ratio were observed to protect against NCDs. While 9 studies found smoking tobacco and alcohol consumption were not significantly associated with the prevalence of NCDs. It is of foremost importance that Indias public health policy focus must shift towards inclusivity as there is an affluent gradient to the increased morbidity and mortality from NCDs. Copyright2024 by authors, all rights reserved. -
Three decades of advances in extraction and analytical techniques for guava (Psidium guajava L.): A review
Despite extensive experimental focus, there remains a notable gap in comprehending the progressive development of these techniques over time. This comprehensive review is dedicated to cataloging the evolution of extraction and analytical methods spanning several decades. In this article, we meticulously traced the development of analytical and extraction techniques. Additionally, we intricately map the periodic discovery of metabolites within guava fruit, aligning them with the chronological utilization of analytical methods. This article results from extensive research and literature analysis to bridge the knowledge gap. Our efforts highlight the advantageous phytochemicals in guava and the diverse extraction techniques available. By encompassing various facets of analytical methods and delving into metabolomics, this review can offer substantial benefits to cultivating future guava varieties. Subsequent sections within this review will serve as a valuable resource, aiding prospective researchers in identifying the most effective extraction and analytical methods for discovering novel metabolites in guava or similar biological samples. Furthermore, through a comprehensive timeline detailing methodological advancements, this review enhances our understanding of the evolutionary path of guava research. Such insights empower researchers to make informed decisions and actively contribute to the continual advancement of the field of research. 2024 -
A Review on Fish Skin-Derived Gelatin: Elucidating the Gelatin PeptidesPreparation, Bioactivity, Mechanistic Insights, and Strategies for Stability Improvement
Fish skin-derived gelatin has garnered significant attention recently due to its abundant availability and promising bioactive properties. This comprehensive review elucidates various intricacies concerning fish skin-derived gelatin peptides, including their preparation techniques, bioactive profiles, underlying mechanisms, and methods for stability enhancement. The review investigates diverse extraction methods and processing approaches for acquiring gelatin peptides from fish skin, emphasizing their impact on the peptide composition and functional characteristics. Furthermore, the review examines the manifold bioactivities demonstrated by fish skin-derived gelatin peptides, encompassing antioxidant, antimicrobial, anti-inflammatory, and anticancer properties, elucidating their potential roles in functional food products, pharmaceuticals, and nutraceuticals. Further, mechanistic insights into the functioning of gelatin peptides are explored, shedding light on their interactions with biological targets and pathways. Additionally, strategies aimed at improving the stability of gelatin peptides, such as encapsulation, modification, and integration into delivery systems, are discussed to extend the shelf life and preserve the bioactivity. Overall, this comprehensive review offers valuable insights into using fish skin-derived gelatin peptides as functional ingredients, providing perspectives for future research endeavors and industrial applications within food science, health, and biotechnology. 2024 by the authors. -
Emerging Nanomaterials as Versatile Nanozymes: A New Dimension in Biomedical Research
The enzyme-mimicking nature of versatile nanomaterials proposes a new class of materials categorized as nano-enzymes, ornanozymes. They are artificial enzymes fabricated by functionalizing nanomaterials to generate active sites that can mimic enzyme-like functions. Materials extend from metals and oxides to inorganic nanoparticles possessing intrinsic enzyme-like properties. High cost, low stability, difficulty in separation, reusability, and storage issues of natural enzymes can be well addressed by nanozymes. Since 2007, more than 100 nanozymes have been reported that mimic enzymes like peroxidase, oxidase, catalase, protease, nuclease, hydrolase, superoxide dismutase, etc. In addition, several nanozymes can also exhibit multi-enzyme properties. Vast applications have been reported by exploiting the chemical, optical, and physiochemical properties offered by nanozymes. This review focuses on the reported nanozymes fabricated from a variety of materials along with their enzyme-mimicking activity involving tuning of materials such as metal nanoparticles (NPs), metal-oxide NPs, metalorganic framework (MOF), covalent organic framework (COF), and carbon-based NPs. Furthermore, diverse applications of nanozymes in biomedical research are discussed in detail. The Author(s), under exclusive licence to Springer Nature Switzerland AG 2024. -
A rapid investigation of near-infrared (NIR) fluorescent switch-on probes for detection and in cellulo tracking of G-quadruplex and double-stranded DNA
This review provides a comprehensive overview of the recent advancements in Near Infrared (NIR) fluorescence switch-on probes designed for the detection and in cellulo tracking of G-quadruplex and double-stranded DNA (dsDNA). G-quadruplexes, non-canonical DNA structures, play pivotal roles in regulating various biological processes, making them critical targets for therapeutic and diagnostic applications. The unique properties of NIR fluorescence probes, such as deep tissue penetration, minimal photodamage, and low autofluorescence background, offer significant advantages for bioimaging. We critically analyze the design strategies, photophysical properties, and binding mechanisms of various NIR fluorescence switch-on probes. Additionally, we discuss their efficacy and specificity in identifying G-quadruplexes and dsDNA within cellular environments. Key challenges and future directions for improving the sensitivity, selectivity, and biocompatibility of these probes are also highlighted. This review aims to underscore the potential of NIR fluorescence probes in advancing our understanding of DNA dynamics and their applications in biomedical research. 2024 The Royal Society of Chemistry. -
Nanomaterials as novel elicitors of pharmacologically active plant specialized metabolites in cell and organ cultures: current status and future outlooks
Specialized plant metabolites, such as phenolics, terpenes, terpenoids, nitrogen-containing compounds, and sulfur-containing compounds, are commercially valuable owing to their wide array of applications in the medical, pharmacological, cosmetic, agriculture, and food industries. Procuring valuable specialized metabolites from wild or cultivated plants is desirable; however, the concentrations and quality of secondary compounds vary between samples. Therefore, plant cells and organ cultures have been selected as viable alternatives for producing specialized metabolites. Elicitation is a strategy used to enhance the accumulation of specialized compounds in cell and organ cultures. Different biotic substances, including signaling chemicals such as salicylic acid and methyl jasmonate, elements of plant cell walls (cellulose and pectin), polysaccharides from microbes (chitin and glucan), and abiotic substances such as inorganic salts, heavy metals, UV radiation, and high salinity, have been successfully tested and used as elicitors for the hyperaccumulation of bioactive substances in cell and organ cultures. Recently, metals, metal oxide nanoparticles, and carbon-based nanomaterials have been used as unique elicitors to boost the synthesis of bioactive compounds in cell and organ cultures. The applications and usage of nanoparticles as elicitors in plant cell and organ cultures are summarized in this review. The mechanism of elicitation, toxicity, benefits, and drawbacks of using nanoparticles in plant cell and organ cultures are discussed. Graphical abstract: (Figure presented.) The Author(s), under exclusive licence to Springer Nature B.V. 2023. -
Mapping the literature on school bullying in India: A scoping review
School bullying has been identified as a major issue among students throughout the world. With around 260 million school students, the largest student population in the world, it becomes essential to investigate this issue in the Indian context. The present work uses the Arksey and O'Malley (2005) framework for scoping review to examine the nature of research on school bullying in India and identify research gaps to be addressed by future research. The review maps the concepts examined, research approaches used, sample characteristics, data collection methods, researcher characteristics, and nature of publications in relation to bullying. Seven databases - JSTOR, PsycNET, Cochrane Reviews, ERIC, MEDLINE, Web of Science, and Cochrane Central Register for Controlled Trials - were searched for sources containing the terms bullying and India published in English and between the years 2015 and 2022. Thirty-eight sources selected for the review suggest that existing research in India on school bullying is limited compared to the West and yet provides a guiding light to future researchers. The findings from this review highlight research gaps in the existing literature and outline areas for further exploration. 2024 Elsevier Ltd -
Developmental prospects of carrageenan-based wound dressing films: Unveiling techno-functional properties and freeze-drying technology for the development of absorbent films A review
This review explores the intricate wound healing process, emphasizing the critical role of dressing material selection, particularly for chronic wounds with high exudate levels. The aim is to tailor biodegradable dressings for comprehensive healing, focusing on maximizing moisture retention, a vital element for adequate recovery. Researchers are designing advanced wound dressings that enhance techno-functional and bioactive properties, minimizing healing time and ensuring cost-effective care. The study delves into wound dressing materials, highlighting carrageenan biocomposites superior attributes and potential in advancing wound care. Carrageenan's versatility in various biomedical applications demonstrates its potential for tissue repair, bone regeneration, and drug delivery. Ongoing research explores synergistic effects by combining carrageenan with other novel materials, aiming for complete biocompatibility. As innovative solutions emerge, carrageenan-based wound-healing medical devices are poised for global accessibility, addressing challenges associated with the complex wound-healing process. The exceptional physico-mechanical properties of carrageenan make it well-suited for highly exudating wounds, offering a promising avenue to revolutionize wound care through freeze-drying techniques. This thorough approach to evaluating the wound healing effectiveness of carrageenan-based films, particularly emphasizing the development potential of lyophilized films, has the potential to significantly improve the quality of life for patients receiving wound healing treatments. 2024 Elsevier B.V. -
Review on lightweight cryptography techniques and steganography techniques for IoT environment
In the modern world, technology has connected to our day-to-day life in different forms. The Internet of Things (IoT) has become an innovative criterion for mass implementations and a part of daily life. However, this rapid growth leads the huge traffic and security problems. There are several challenges arise while deploying IoT. The most common challenges are privacy and security during data transmission. To address these issues, various lightweight cryptography and steganography techniques were introduced. These techniques help secure the data over the IoT. The hybrid of cryptography and steganography mechanisms provides enhanced security to confidential messages. Any messages can be secured by cryptography or by embedding the messages into any media files including text, audio, image, and video using steganography. Hence, this article has provided a detailed review of efficient, lightweight security solutions based on cryptography and steganography and their function over IoT applications. The objective of the paper is to study and analyze various Lightweight cryptography techniques and Steganography techniques for IoT. A few works of literature were reviewed in addition to their merits and limitations. Furthermore, the common problems in the reviewed techniques are explained in the discussion section with their parametric comparison. Finally, the future scope to improve IoT security solutions based on lightweight cryptography and steganography is mentioned in the conclusion part. The Author(s) under exclusive licence to The Society for Reliability Engineering, Quality and Operations Management (SREQOM), India and The Division of Operation and Maintenance, Lulea University of Technology, Sweden 2024. -
GrapheneLiquid Crystal Synergy: Advancing Sensor Technologies across Multiple Domains
This review explores the integration of graphene and liquid crystals to advance sensor technologies across multiple domains, with a focus on recent developments in thermal and infrared sensing, flexible actuators, chemical and biological detection, and environmental monitoring systems. The synergy between graphenes exceptional electrical, optical, and thermal properties and the dynamic behavior of liquid crystals leads to sensors with significantly enhanced sensitivity, selectivity, and versatility. Notable contributions of this review include highlighting key advancements such as graphene-doped liquid crystal IR detectors, shape-memory polymers for flexible actuators, and composite hydrogels for environmental pollutant detection. Additionally, this review addresses ongoing challenges in scalability and integration, providing insights into current research efforts aimed at overcoming these obstacles. The potential for multi-modal sensing, self-powered devices, and AI integration is discussed, suggesting a transformative impact of these composite sensors on various sectors, including health, environmental monitoring, and technology. This review demonstrates how the fusion of graphene and liquid crystals is pushing the boundaries of sensor technology, offering more sensitive, adaptable, and innovative solutions to global challenges. 2024 by the authors. -
Light as an elicitor for enhanced production of secondary metabolites in plant cell, tissue, and organ cultures
Currently, in vitro cell, tissue, and organ cultures are used to produce plant secondary metabolites that are used as natural coloring agents, nutraceuticals, and medications. Various strategies have been applied for the hyperaccumulation of biomass and bioactive secondary compounds in vitro. The elicitation of cultured cells and organs with biotic and abiotic elicitors is an excellent strategy that has yielded promising results. Among various abiotic elicitors, light parameters such as light quality, intensity, and photoperiod have evolved as biotechnological tools to elicit cultures. Of the various light sources tested, ultraviolet (UV) lights, particularly UV-B, red, blue, and a mixture of light emitted by fluorescent light or light-emitting diodes, have yielded outstanding results and boosted the accumulation of bioactive compounds in cultured cells and organs. The objective of the current study was to evaluate light as an elicitor source and summarize the advantages and limitations of various light sources as elicitors for the bioaccumulation of secondary metabolites in vitro. The mechanism of the elicitation of secondary metabolism by UV and spectral light is discussed in this review. The Author(s), under exclusive licence to Springer Nature B.V. 2024. -
Unraveling connections with artificial sweeteners and their impact on human health: A comprehensive review
There is a recent trend showing an uptick in the artificial sweetener's usage, particularly the nonnourishing variety. The allure of a low-calorie choice that lets people indulge in their sweet tooths while consuming less calories overall is what motivates this. Children's food products often contain a substantial number of artificial sweeteners due to their properties that aid in moisture retention, act as fillers, and serve as bulking agents. This article provides a comprehensive overview of artificial sweeteners and influences in human wealth. Studies have linked the use of artificial sweeteners to premature birth, highlighting the teratogenic potential of these compounds, particularly in beverages. Pregnant women who incorporate nonnutritive sweeteners into their diet during pregnancy are more likely to have children with birth defects, as indicated by studies on the subject. Artificial sweeteners should not be added to food for children because studies show that eating them while a child's body is still developing might disturb the balance of gut microbiota and cause potential problems like heart disease, stroke, and cognitive decline. The ingestion of nonnourishing sweeteners has adverse effects on the fertility of both men and women. Studies indicate that exceeding the recommended daily consumption that the FDA has set for artificial sweeteners can result in conditions of infertility for both genders. Additionally, there is a connection between the onset of cancer and the use of artificial sweeteners. Presently, a considerable amount of research relies on animal models rather than human ones, creating a notable gap in research. The limitation of extensive human model studies represents a drawback in validating results. Furthermore, there is a necessity for increased research focused on advancing techniques that can minimize the adverse effects of artificial sweeteners, making them more suitable for addressing issues related to obesity and various types of diabetes. 2024 The Author(s). eFood published by John Wiley & Sons Australia, Ltd. on behalf of International Association of Dietetic Nutrition and Safety. -
Bioactive nanoparticles derived from marine brown seaweeds and their biological applications: a review
The biosynthesis of novel nanoparticles with varied morphologies, which has good implications for their biological capabilities, has attracted increasing attention in the field of nanotechnology. Bioactive compounds present in the extract of fungi, bacteria, plants and algae are responsible for nanoparticle synthesis. In comparison to other biological resources, brown seaweeds can also be useful to convert metal ions to metal nanoparticles because of the presence of richer bioactive chemicals. Carbohydrates, proteins, polysaccharides, vitamins, enzymes, pigments, and secondary metabolites in brown seaweeds act as natural reducing, capping, and stabilizing agents in the nanoparticles synthesis. There are around 2000 species of seaweed that dominate marine resources, but only a few have been reported for nanoparticle synthesis. The presence of bioactive chemicals in the biosynthesized metal nanoparticles confers biological activity. The biosynthesized metal and non-metal nanoparticles from brown seaweeds possess different biological activities because of their different physiochemical properties. Compared with terrestrial resources, marine resources are not much explored for nanoparticle synthesis. To confirm their morphology, characterization methods are used, such as absorption spectrophotometer, X-ray diffraction, Fourier transforms infrared spectroscopy, scanning electron microscope, and transmission electron microscopy. This review attempts to include the vital role of brown seaweed in the synthesis of metal and non-metal nanoparticles, as well as the method of synthesis and biological applications such as anticancer, antibacterial, antioxidant, anti-diabetic, and other functions. Graphical abstract: (Figure presented.). The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024. -
Exploring the far-reaching consequences of malnutrition during pregnancy and beyond: A comprehensive review
In India, maternal and infant malnutrition continues to be a significant contributor to health problems. Fetal malnutrition can result from an inadequate nutrient supply, necessary nutrition services, and ideal practices before, during, and following pregnancy. This comprehensive review delves into the complex relationships among hormone changes, microbial ecosystems, and nutrition, and how these relationships affect the health of mothers and their offspring. The review highlights how important it is to maintain good nutrition during pregnancy and to comprehend the dietary modifications that pregnant people make on their own to create interventions that work. Important minerals like calcium, iron, folic acid, iodine, and vitamin D are covered. Acknowledging the mutualistic association between the eating habits of mothers and the diverse microbiomes found in their gut, vagina, and oral channels, the review explores the influence on hormone levels and their consequences during gestation. Diverse fetal developmental needs are depicted by the table that outlines food requirements for each of the three trimesters. The detrimental effects of poor prenatal nutrition on a mothers health and its repercussions for neonates are examined. The effects of malnutrition after delivery, including difficulties throughout pregnancy, healing periods, and general effects on mental and physical health, are well studied. The study, which adopts a worldwide viewpoint, finds that societal norms, information gaps, and poverty are the main causes of malnutrition. Prevention techniques are discussed, emphasizing the significance of taking a comprehensive approach to addressing this vital issue in both the Indian and global contexts. 2024 Visagaa Publishing House. -
Spiritual Intelligence and Spiritual Care in Nursing Practice: A Bibliometric Review
Spiritual intelligence (SI) has recently gained traction in various fields, including nursing. Given the increasing emphasis on patient-centred care and the holistic well-being of patients and nurses, SI is particularly relevant in nursing practice. A bibliometric analysis of recent publications (20142024) in the field helps synthesise and evaluate the existing research on SI in the general field of nursing, identify literature gaps, suggest future research directions and raise awareness of the importance of SI in nursing practice. The present study reports bibliometric data (n = 461) from the Scopus database on SI, spiritual quotient and spiritual care in nursing and health care. The data are analysed using MS Excel and VOSviewer software. The publications trend analysis revealed a significant increase in SI-related publications since 2015. The study presents top-cited articles. Journal of Religion and Health was found to be a prominent journal with the maximum number of publications, and Sage was found to be the top publisher of journals with articles on SI. Network visualisation reveals central figures such as Wilfred McSherry, Trove Giske, Elizabeth Johnston Taylor, Fiona Timmins, Silvia Caldeira and Linda Ross as key researchers in the field. The United States and Iran have the most substantial connections of authors publishing on SI. This study reveals an increasing interest in SI and care within nursing research, confirming its growing significance in the field. By reporting areas where research on SI in nursing remains underdeveloped, the study paves the way for the development of new or updated curricula in nursing programs. The study can guide faculty development initiatives by highlighting the importance of SI and providing resources for educators to incorporate these concepts into their teaching. This study presents specific research questions to address these knowledge gaps. Future studies which can address these questions will enrich nursing education and practice, leading to improved patient outcomes and enhanced nurse well-being using the full potential of SI in nursing practice. 2024 Published by Scientific Scholar on behalf of Indian Journal of Palliative Care. -
Amyotrophic Lateral Sclerosis: Insights and New Prospects in Disease Pathophysiology, Biomarkers and Therapies
Amyotrophic Lateral Sclerosis (ALS) is a severe neurodegenerative disorder marked by the gradual loss of motor neurons, leading to significant disability and eventual death. Despite ongoing research, there are still limited treatment options, underscoring the need for a deeper understanding of the diseases complex mechanisms and the identification of new therapeutic targets. This review provides a thorough examination of ALS, covering its epidemiology, pathology, and clinical features. It investigates the key molecular mechanisms, such as protein aggregation, neuroinflammation, oxidative stress, and excitotoxicity that contribute to motor neuron degeneration. The role of biomarkers is highlighted for their importance in early diagnosis and disease monitoring. Additionally, the review explores emerging therapeutic approaches, including inhibitors of protein aggregation, neuroinflammation modulators, antioxidant therapies, gene therapy, and stem cell-based treatments. The advantages and challenges of these strategies are discussed, with an emphasis on the potential for precision medicine to tailor treatments to individual patient needs. Overall, this review aims to provide a comprehensive overview of the current state of ALS research and suggest future directions for developing effective therapies. 2024 by the authors. -
Influencer Marketing and Consumer Behaviour: A Systematic Literature Review
Influencer marketing is an emerging area in the field of marketing. Specifically, this topic grabs the attention of several academicians and practitioners because of the key role played by influencers to stimulate consumer behaviour. Significantly, a systematic way of analysing and summarising the works of literature in this nascent area is necessary. A systematic literature review provides a comprehensive overview of the whole literature studied. From this knowledge, a systematic literature review has been undertaken from the period of 2016 to 2021 based on 65 articles from the ABDC journal to fetch relevant research themes, methodology, theories, variables, antecedents and consequences and potential research gaps. From this information, this research proposed an integrative framework which depicts the role of social media influencers in activating consumer behaviour. Future research direction has presented comprising of knowledge gap in the existing literature from key areas such as theory, methodology and settings. This research provides implications for both theories and practice. 2022 Management Development Institute. -
Partition Refugees in Jammu Cry for Protection of Land and Job Rights
Article 370 was presented as an obstacle in the complete integration of Kashmir and it had denied citizenship and land rights to around 1.5 lakh West Pakistan Refugees (all Hindus) since their migration in 1947. However, after the lapse of merely five years of the abrogation, these WPRs, the new citizens of Jammu and Kashmir, have started feeling disillusioned and demanding protection of lands and jobs under Article 371 of the Indian Constitution. 2024 Economic and Political Weekly. All rights reserved.