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Development of Green Synthesized Novel Carbon Dots from Ruta Graveolens L. for Fluorescent and Intracellular Sensing of Mercury Ions in Pico-molar (pm) Concentration
Green nanotechnology, which uses carbon nanomaterials for environmental remediation, is the pioneer among the prevailing approaches for the production and characterization. In the present study, highly fluorescent carbon dots (CDs) from Ruta Graveolens (ARH-CD) is developed, and its efficacy as a fluorescent sensor and biomarker is investigated. They act as a fluorescence sensor for Hg2+ over an extensive concentration range of 1 picomolar (pm) to 1 molar (m), with a detection limit as low as 26.75 pm. The studies reveal ARH-CD as an effective biomarker for intracellular toxicity analysis and a fluorescent probe for multi-colored (blue, green, and red) imaging of HEK293 cell lines. After 24 h of incubation, it is found that the ARH material reveals noticeable biocompatibility and visible fluorescence, with a viability of 98.88% at 5 gmL?1 and over 78.33% even at a concentration of 100 gmL?1. The IC50 value for the MTT assay for cell viability results is calculated to be 224.56 4.67 g, which further confirms the appreciable biocompatibility of the ARH-CD. The obtained samples are effective in being inspected for the intracellular detection of Hg2+ and serve as a possible candidate for cell imaging. 2024 Wiley-VCH GmbH. -
Development of Guidelines for Spouses Engaged in Home-Based Care of Persons With Motor Neuron Disease From Indian Context
Background: The caregivers of persons with motor neuron disease (MND) have several needs that are usually not voiced on any platform. Aim: To explore the lived experience of spouses of persons with MND, identify their needs and develop guidelines for better home-based care. Method: An exploratory study with 3-point in-depth interviews among 13 participants was conducted. Participants were the spouses of persons with MND under treatment at a national quaternary referral center. The interpretative phenomenological analysis identified participants needs. These needs, with literature review synthesis, guided the drafting of guidelines, which was validated by experts. Results: The needs were emotional, social, care systems, and skills. The guidelines developed contained 2 sections (1) Information for the spouses: understanding MND, communication, symptom management, marital relationship, palliative care, and everyday life made easier. (2) Well-being of the spouse caregivers: well-being of the spouse caregivers, self-care, mental health, supporting carers in palliative care, where to find help. Conclusion: The guidelines can be developed as a manual for the caregivers and for training healthcare professionals working with neurodegenerative conditions. The Author(s) 2022. -
Development of high performance polymer composites by additive manufacturing
Additive manufacturing, often known as 3D printing, is a process that involves the manufacture of physical things in a manner that is similar to building them up layer by layer. As a result of its utilization of automated procedures to generate complicated three-dimensional forms, which are either difficult or impossible to produce using conventional methods, fused deposition modeling is a typical approach that uses heat to assist in the extrusion process. The term "high-performance polymer" refers to a group of polymer materials that are known to maintain their desirable mechanical, thermal, and chemical properties when subjected to harsh environments such as high temperatures, high pressures, and corrosive chemicals. This chapter starts off with a brief introduction of conductive and high-performance polymer composites, followed by a rundown of how these materials are utilized in the 3D printing process. 2023, IGI Global. All rights reserved. -
Development of interactive e-content to enhance listening skill and language comprehension among secondary school students
The present study aimed to develop interactive e-content, conduct expert validation, and examine the appropriate level. The researchers used a purposive sampling technique to select the sample of 100 secondary school students and 35 teachers from the Kerala state scheme. The researchers adopted the analysis, design, development, implementation, and evaluation (ADDIE) model to develop interactive e-content. The study employed two quantitative methods. Firstly, the study administered expert validation sheets to three content and two media experts to validate developed interactive e-content. The study utilized the percentage analysis to evaluate the results of the expert validation sheets. Secondly, the study administered a survey questionnaire to 100 secondary school students and 35 teachers to examine the appropriate level of interactive e-content. The study employed the correlation method to analyze the questionnaire results, examining the strength and direction of relationships between variables. The average score of content expert validation is 95.5% and media expert validation is 91.5% confirm that the developed interactive e-content is highly valid and appropriate. A major challenge for the researchers was the insufficient internet speed in rural areas of Kerala. The study recommends that teachers have to develop interactive multimedia teaching-learning aids to improve listening, speaking, reading, and writing (LSRW) among students. 2026 Institute of Advanced Engineering and Science. All rights reserved. -
Development of Internet of Things Platform and Its Application in Remote Monitoring and Control of Transformer Operation
Internet of Things platforms deployed on the system will exhibit numerous benefits such as real time monitoring, faster operation and cost effectiveness. A system oriented IoT platform is developed which features database connotation, web services, setup portal, cloud hosting, drivers or listener for programming languages and hardware devices. The functional parameters of transformer in electrical power system vary around the limit and beyond, which is observed by the IoT platform for remote analysis and to report deformation in the winding. The frequency response measurement from the transformer terminal unit is send to cloud database which is then fetched to remote application through IoT client. At remote monitoring tool, the diagnostic algorithm is executed to estimate the location and extent of deformation. IoT based frequency response analyzer and transformer diagnostic tools developed reports the status of the transformer health condition. Depending upon the extent of deformation, the transformer is isolated from power system. Springer Nature Switzerland AG 2020. -
Development of LIDAR-SLAM Integrated Low Cost Health Care Monitoring Robot with Sustainable Material
Beyond the global pandemic, healthcare has faced a myriad of challenges, from rising costs and accessibility issues to the need for precision in patient care and efficient medication delivery. This project embodies a visionary response to the multifaceted challenges faced by healthcare systems in health centers located in rural areas. The proposed research work focused on design and development of a health care monitoring robot with integration of 3D LIDAR Simultaneous Localization and Mapping (SLAM) based navigation approach, introduction of sustainable materials like bamboo and wood composites for development of robotic arm and robotic body frames. Also, from the initial tests it has been observed that with the developed mobile robot functions like precision medicine delivery, Open AI-Enabled continuous monitoring, hospital environment sanitization and emergency oxygen supply can be performed efficiently. 2024 IEEE. -
Development of Mindfulness Based Solution Focused Brief Therapy for Children (MBSFT-C): An International Delphi Study
Internalizing and externalizing behavioral issues among children tend to appear together and are often interrelated. A combination of Solution-focused brief therapy (SFBT) and Mindfulness is theoretically promising in reducing the co-occurrences of internalizing and externalizing issues. In this study, we developed and validated MBSFT-C, which addresses internalizing and externalizing behavioral issues. Preliminary components of MBSFT-C were developed, integrating the philosophies of Mindfulness and Solution Focused Brief Therapy. We used a two-round Delphi survey to finalize and validate these components. In the first round, the experts provided a free-text review of the initial components of MBSFT-C, which were then analyzed thematically using QDA Miner v2.0.9 software. In the second round, the experts evaluated the final components of MBSFT-C and reached a consensus using a 10-point visual analog scale. Thematic analysis of review 1 revealed three themes, Validation, Additions, and Modifications, based on which the final draft of MBSFT-C was developed. The final draft included two major components, Mindful Solution Focused Engagement and Family Mindfulness Skills. All the components of MBSFT-C achieved international expert consensus with a 70% agreement in review 2. The mean score for components by the experts ranged between 7.50 and 8.00 out of 10 on a visual analog scale, with a standard deviation ranging from 1.94 to 2.95. MBSFT-C will provide clinicians with a well suited, empirically developed, manualized comprehensive therapy that meets the special requirements of children. 2025 Taylor & Francis Group, LLC. -
Development of perceived prenatal maternal stress scale
Background: Pregnancy is a state, which is often associated with extreme joy and happiness. Women undergo a number of physiological and psychological changes during pregnancy, which are often stressful if aligned with other adverse life events, compromising their health and well-being. However, there exists no comprehensive psychological instruments for measuring this stress. Objectives: The study was conducted to develop a multidimensional scale to assess prenatal maternal stress (PNMS) comprehensively. Methods: The initial phase of the study focuses on developing items and assessing the content validity of these items. The second phase focuses on pilot-testing and field-testing the newly developed perceived PNMS scale (PPNMSS) among 356 pregnant women belonging to different parity and trimester from November 2015 to October 2016. Results: The underlying factor structure of the 28-item PPNMSS had explored using exploratory factor analysis. The final scale is retained with 15 items having considerable item loading under four major factors as follows: perceived social support, pregnancy-specific concerns, intimate partner relations, and financial concerns. Reliability of each of these dimensions was assessed using Cronbach's alpha. Convergent and divergent validity of the scale was assessed by correlating the scores with perceived stress scale and the World Health Organization (five) well-being index (1998 version). Conclusions: As a comprehensive scale, PPNMSS is efficient to measure PNMS, which facilitates an early detection of stress and depression among pregnant women and timely intervention by health care professionals. -
Development of pluronic F127 and folic acid coated TiO2nanoparticles for antimicrobial and anticancer applications
Functionalizing metal oxide nanoparticles with polymers and folic acid enhances eco-friendly synthesis, therapeutic efficiency, and cost-effectiveness. This study reports the green synthesis of titanium dioxide (TiO?) and folic acidPluronic F127modified TiO?(TiPFFA) nanoparticles usingPsidium guajavaleaf extract as a natural reducing and stabilizing agent. X-ray diffraction (XRD) analysis confirmed that both nanoparticles crystallized in the rutile phase. Morphological characterization by FESEM and TEM showed that the nanoparticles were spherical with uniform size distribution. FTIR spectroscopy showed TiOTi (789cm?1) and TiO (666cm?1) for TiO?; TiPFFA had extra peaks at 951 and 640cm?1, confirming the lattice. PL spectra exhibited emission peaks at 518nm (TiO?) and 520nm (TiPFFA), indicating oxygen vacancies linked to reactive oxygen species generation. Antimicrobial tests against methicillin-resistantStaphylococcus aureus andCandida albicansshowed superior activity of TiPFFAnanoparticles compared to TiO?. Cytotoxicity assays on MDA-MB-231 breast cancer cells and L929 fibroblast cells demonstrated enhanced anticancer activity and better biocompatibility for TiPFFA. These findings highlight TiPFFA nanoparticles as promising candidates for targeted cancer therapy and as antimicrobial agents. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2025. -
Development of smart energy monitoring using NB-IOT and cloud
IoT-based applications are growing in popularity nowadays because they offer effective answers to numerous current problems. In this research, With the aim of decreasing human efforts for monitoring the power units and increasing users' knowledge of excessive electricity usage, an IoT-based electric metre surveillance system utilising an Android platform has been developed. With the help of an Arduino Uno and an optical sensor, the electric analyser pulse is captured. To reduce human mistake and the expense of energy usage, a low-cost wireless network of sensors for digital energy metres is implemented alongside a smartphone application that can autonomously read the metre of the unit. In this research, an intelligent power monitoring system with effective communication modules has been developed to make wise use of the electricity. The controller, NB-IoT connection module, and cloud are the three main components of an IOT-based smart energy metre system. The controller is essential for maintaining the functionality of each component. This solution reduces the need for human involvement in electricity maintenance by connecting energy metres to the cloud using an NB-IoT communication module. The IoT-based metre reading system in the proposed work is created to monitor and analyse the metre reading, and the service provider can cut off the source of electricity whenever the customer fails to pay the monthly bill. It also eliminates the need for human intervention, provides accurate metre reading, and guards against billing errors. The proposed SPM improves the overall accuracy ranges of 7.42, 27.83, and 20% better than DR, OREM, and SLN respectively. 2023 -
Development of the House of Collaborative Partnership to overcome supply chain disruptions: evidence from the textile industry in India
Collaboration in a supply chain becomes a significant competitive weapon for member firms in an uncertain business environment. The present study develops a model of supply chain collaboration named as House of Collaborative Partnership (HCP) and includes the enablers and impeders of a successful Collaborative Partnership (CP). Model development follows a three-phase process. The first phase consists of the identification of enablers and impeders of CP based on the literature review and experts opinions. The second phase applies Total Interpretive Structural Modelling (TISM) as a tool to construct hierarchical structures of the enablers and impeders of CP. The third phase deals with the development of HCP based on the hierarchical structures of enablers and impeders. The HCP is then validated with two case studies in the Indian textile industry. Eight enablers and seven impeders were identified in the first phase. After analyzing these factors with TISM, the HCP was developed consisting of four parts: Foundation, Columns, Beam, and Roof. The existence of trust, commitment to long-term collaboration, top management support, adequate financial support, ability to deal with technological changes, and providing regular training to employees constitute the HCP Foundation to achieve supply chain collaboration. The study concludes with the managerial implications of HCP to help supply chain partners in becoming resilient during an uncertain business environment. 2022 Informa UK Limited, trading as Taylor & Francis Group. -
Development ofNew Fidelity Theorems inQuantum Communication
Fidelity estimates the closeness or degree of overlap between a pair of unknown quantum systems. In quantum information processing study, a primary task is to estimate the fidelity of a pure states pair in a 2-dimensional Hilbert space or between a mixed state, ?, and pure state existing in N dimensional Hilbert space while transmitting them through noisy environments. This paper suggests two theorems to estimate fidelity while proving and justifying them numerically. The first theorem computes fidelity between pure states and the second estimates fidelity between mixed and pure states. The mathematical basis of the theorems confirms accuracy in estimation while dealing with single- and multiqubit system environments. The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2026. -
Development through ICT: A study on teachers perspectives on challenges in online education for tribal students amid COVID-19
Online education became an integral part of the education system during the COVID-19 pandemic. All the schools, colleges and universities adopted new technology in teaching-learning pedagogy. Academicians and students were taught to practice online education with many challenges and difficulties. The Constitution of India includes many beneficial provisions to promote the integral development of scheduled tribes. It enables them and protects them from socioeconomic status and forms of exploitation. In Kerala, the Scheduled Tribes Development Department is implementing various programs for the educational, social and economic development of Scheduled Tribes. Kerala is the most literate state in India. It creates a strong academic foundation at the school level. Even though the COVID-19 pandemic spread throughout the world, the government continued education in the state through the VICTERS educational television channel with the help of various ICT tools. This studys objective is to determine the challenges faced by tribal students in the Idukki District of Kerala State in online education and to understand the social and technological challenges they face in the learning process. An in-depth interview method was adopted for the study. This qualitative study explored the perspectives of teachers who teach tribal students. 2025 Malque Publishing. All rights reserved. -
Development through ICT: A study on teachers perspectives on challenges in online education for tribal students amid COVID-19
Online education became an integral part of the education system during the COVID-19 pandemic. All the schools, colleges and universities adopted new technology in teaching-learning pedagogy. Academicians and students were taught to practice online education with many challenges and difficulties. The Constitution of India includes many beneficial provisions to promote the integral development of scheduled tribes. It enables them and protects them from socioeconomic status and forms of exploitation. In Kerala, the Scheduled Tribes Development Department is implementing various programs for the educational, social and economic development of Scheduled Tribes. Kerala is the most literate state in India. It creates a strong academic foundation at the school level. Even though the COVID-19 pandemic spread throughout the world, the government continued education in the state through the VICTERS educational television channel with the help of various ICT tools. This studys objective is to determine the challenges faced by tribal students in the Idukki District of Kerala State in online education and to understand the social and technological challenges they face in the learning process. An in-depth interview method was adopted for the study. This qualitative study explored the perspectives of teachers who teach tribal students. 2025 Malque Publishing. All rights reserved. -
Development vs. Rights A Case for Sustainable Development of Onge Tribes of Little Andaman
Human rights and environmental protections are often violated as a consequence of development activities. In addition to harming the environment, this increases the marginalisation of those who are already marginalised. The development paradigm that is based on the interests of the majority not only tends to retard the indigenous people but also renders them incapable of competing with the majority. For the indigenous people, development has always been a problem rather than a solution. Development initiatives under the umbrella of globalisation with a label of monotony, ignore the aspects of the diverse livelihoods of many indigenous peoples. The Niti Aayog proposed in its vision document, the Sustainable Development of Little Andaman, in 2021, that the island should be developed into a megacity by utilising its natural features and strategic location. The long-term objective is to develop the island into a major financial tourism hub that can rival Hong Kong and Singapore. This plan will, on the one hand, advance commerce, employment, and economic growth; on the other hand, environmental conservation issues will also arise. Concerns over this vision document have indeed been voiced by several academics, environmentalists, and conservationists due to issues with Onge indigenous rights, ecological fragility, and earthquake and tsunami susceptibility. In this context, the research article aims to study and analyse the proposed megacity project and its impact on the rights of Onge tribes and the environment. Sahana Florence and Achyutananda Mishra, 2024. -
Development vs. Rights A Case for Sustainable Development of Onge Tribes of Little Andaman
Human rights and environmental protections are often violated as a consequence of development activities. In addition to harming the environment, this increases the marginalisation of those who are already marginalised. The development paradigm that is based on the interests of the majority not only tends to retard the indigenous people but also renders them incapable of competing with the majority. For the indigenous people, development has always been a problem rather than a solution. Development initiatives under the umbrella of globalisation with a label of monotony, ignore the aspects of the diverse livelihoods of many indigenous peoples. The Niti Aayog proposed in its vision document, the Sustainable Development of Little Andaman, in 2021, that the island should be developed into a megacity by utilising its natural features and strategic location. The long-term objective is to develop the island into a major financial tourism hub that can rival Hong Kong and Singapore. This plan will, on the one hand, advance commerce, employment, and economic growth; on the other hand, environmental conservation issues will also arise. Concerns over this vision document have indeed been voiced by several academics, environmentalists, and conservationists due to issues with Onge indigenous rights, ecological fragility, and earthquake and tsunami susceptibility. In this context, the research article aims to study and analyse the proposed megacity project and its impact on the rights of Onge tribes and the environment. Sahana Florence and Achyutananda Mishra, 2024. -
Developmental prospects of carrageenan-based wound dressing films: Unveiling techno-functional properties and freeze-drying technology for the development of absorbent films A review
This review explores the intricate wound healing process, emphasizing the critical role of dressing material selection, particularly for chronic wounds with high exudate levels. The aim is to tailor biodegradable dressings for comprehensive healing, focusing on maximizing moisture retention, a vital element for adequate recovery. Researchers are designing advanced wound dressings that enhance techno-functional and bioactive properties, minimizing healing time and ensuring cost-effective care. The study delves into wound dressing materials, highlighting carrageenan biocomposites superior attributes and potential in advancing wound care. Carrageenan's versatility in various biomedical applications demonstrates its potential for tissue repair, bone regeneration, and drug delivery. Ongoing research explores synergistic effects by combining carrageenan with other novel materials, aiming for complete biocompatibility. As innovative solutions emerge, carrageenan-based wound-healing medical devices are poised for global accessibility, addressing challenges associated with the complex wound-healing process. The exceptional physico-mechanical properties of carrageenan make it well-suited for highly exudating wounds, offering a promising avenue to revolutionize wound care through freeze-drying techniques. This thorough approach to evaluating the wound healing effectiveness of carrageenan-based films, particularly emphasizing the development potential of lyophilized films, has the potential to significantly improve the quality of life for patients receiving wound healing treatments. 2024 Elsevier B.V. -
Developmental Regulations to Conserve Catchment Area of an Urban Water Body: A Case of Upper Lake in the City of Bhopal, Madhya Pradesh, India
A lake reflects its catchment and provides a wide range of ecological services useful for the sustenance and betterment of human lives and other living organisms. The fast-paced developmental activities in the catchment area of lakes and over-consumption of available resources are resulting in the degradation of ecological services of the lake. The Upper Lake in Bhopal, a million-plus population city situated in the central part of India, has been selected for the study. The current regulatory regime for environmental conservation of the catchment area comprises a legislative framework and a set of regulatory institutions. Inadequacies in each accelerates environmental degradation of the Upper Lake, delays and escalates cost of developmental projects. This paper is an attempt to find out gaps in the existing institutional framework to conserve the catchment area. The present study focused on identifying and assessing major issues pertaining to the degradation of the Upper Lake, thereafter establishing a cause-and-effect relationship between anthropogenic activities and their environmental impacts. Subsequently, formulating developmental regulations forconserving theUpper Lake and its catchment area. Primarily, GIS application has been employed to delineate the catchment area of the Upper Lake by using catchment area assessment technique. Furthermore, a primary survey targeting the village stakeholders in the catchment area was conducted to analyze socio-economic profile and assess the agricultural practices adopted. Finally, formulated an institutional framework to conserve, govern and monitor the catchment area and the Upper Lake from the anthropogenic issues. The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2024. -
Developments in Feeds in Aquaculture Sector: Contemporary Aspects
Aquaculture, one of the largest protein food generating sectors, greatly relies on nutrition. Up to the present time, the dependency of the aqua feed sector on fish meal and fish oil as protein and lipid sources, respectively, was too high, which led to its inadequacy and over-exploitation of marine resources. Recently, numerous researches with locally available feed ingredients have been accomplished. There is urgency for a move from fish meal to plant/terrestrial animal/microbial proteins within the aquaculture industry as over-exploitation of wild fishes has negative ecological consequences. Plant proteins cannot successfully replace fish meal due to poor protein digestibility and essential amino acids imbalance, urging feed concerns to search for cheaper and nutritious fish meal alternatives from animal origin. In order to overcome the indiscriminate use of antimicrobial drugs, the concept of probiotics in aquaculture has received firm encouragement in recent years due to their wise inhibitory mechanisms and safeness. Negative perception for synthetic antioxidants among fish farmers and their unreliable nature has resulted in the research for non-synthetic, food derived antioxidants that could encounter and neutralize the detrimental effects of free radicals. In line with this, there is a strong captivation to research on the individual or synergistic effects of protein hydrolysates, peptide fragments, and free amino acids that could innately exhibit antioxidative activity. Commercialization of economical feeds with antioxidative feed ingredients could strengthen the profits of feed processors. Recent development in the aquaculture sector propelled by the application of biotechnological methods has clearly highlighted the need for development of functional feeds through incorporation of bioactive molecules. In the last few decades, the global aqua feed industry has witnessed milestones in the development of feed ingredients from waste raw materials and sustainable alternatives to antibiotics and chemicals used to tackle the disease outbreak in aquaculture. As the health and immunity of fishes primarily depend on their nutritional pattern, a great research interest is extended on incorporation of biomolecules like single-cell proteins, animal proteins, plant metabolites, biopolymers, and enzymes as feed ingredients to enhance the nutritive quality and immune tolerance in fishes. Besides the focus on the feed ingredients, the modification and development of fermentation strategies for producing probioticbased feed and enzyme-assisted bioconversion into valuable feed ingredients is also gaining more importance. This chapter deals with the recent development in the aqua feed industry with specific reference to the incorporation of non-conventional feed ingredients like animal/microbial proteins, biopolymers, enzymes, and other immunostimulatory compounds in aqua feed and their impact analysis in improving the growth profile and pathogen tolerance in fishes. The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2022. -
DFT Aware Test Architecture for Communication ICs: ATPG-Based Fault Detection on Lower Technology Node
In this research, hafnium dioxide (HfO2) and titanium dioxide (TiO2) are investigated as advanced gate dielectrics for GaN-based MISHEMTs on diamond substrates. AlGaN/GaN MISHEMTs, incorporating HfO2 and TiO2 as gate dielectrics, have been rigorously analyzed and optimized for RF and DC performance through ATLAS TCAD simulations. The MISHEMTs with HfO2 gate dielectrics exhibited impressive metrics: a high drain current density (IDS) of 3.62 A/mm, a breakdown voltage (VBR) of 998 V, a transconductance (gm) of 1.09 S/mm, and a cutoff frequency (fT) of 49 GHz. Conversely, the MISHEMTs utilizing TiO2 as the passivation layer demonstrated even superior performance, achieving an IDS of 3.7 A/mm, a V_B of 1168 V, a gm of 1.13 S/mm, and an fT of 48 GHz. Both dielectric materials contributed to a notably low on-resistance of 4.9 ?mm. The synergistic effect of the diamond substrate with high-performance HfO2 or TiO2 gate dielectrics positions these MISHEMTs as highly promising candidates for next-generation power switching and RF applications, due to their enhanced efficiency and robustness under high-power and high-frequency conditions. The proposed work improves the performance enhancement of Metal-Insulator-Semiconductor High Electron Mobility Transistors (MISHEMTs) with inclusion of diamond substrate. Diamond substrate to its wide energy bandgap ranges of 5.5 eV for used materials for both power electronics and RF applications electrical and Thermal properties are concerned in its high. 2025, Society for Communication and Computer Technologies. All rights reserved.