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The Role of Nanoparticles in Response of Plants to Abiotic Stress at Physiological, Biochemical, and Molecular Levels
In recent years, the global agricultural system has been unfavorably impacted by adverse environmental changes. These changes in the climate, in turn, have altered the abiotic conditions of plants, affecting plant growth, physiology and production. Abiotic stress in plants is one of the main obstacles to global agricultural production and food security. Therefore, there is a need for the development of novel approaches to overcome these problems and achieve sustainability. Nanotechnology has emerged as one such novel approach to improve crop production, through the utilization of nanoscale products, such as nanofertilizer, nanofungicides, nanoherbicides and nanopesticides. Their ability to cross cellular barriers makes nanoparticles suitable for their application in agriculture. Since they are easily soluble, smaller, and effective for uptake by plants, nanoparticles are widely used as a modern agricultural tool. The implementation of nanoparticles has been found to be effective in improving the qualitative and quantitative aspects of crop production under various biotic and abiotic stress conditions. This review discusses various abiotic stresses to which plants are susceptible and highlights the importance of the application of nanoparticles in combating abiotic stress, in addition to the major physiological, biochemical and molecular-induced changes that can help plants tolerate stress conditions. It also addresses the potential environmental and health impacts as a result of the extensive use of nanoparticles. 2023 by the authors. -
Synthetic biology for sustainable food ingredients production: recent trends
Problems with food security result from increased population, global warming, and decrease in cultivable land. With the advancements in synthetic biology, microbial synthesis of food is considered to be an efficient alternate approach that could permit quick food biosynthesis in an eco-friendly method. Furthermore, synthetic biology can be assumed to the synthesis of healthy or specially designed food components like proteins, lipids, amino acids and vitamins and widen the consumption of feedstocks, thus offering possible resolutions to high-quality food synthesis. This review describes the impact of synthetic biology for the microbial synthesis of various food ingredients production. 2022, Jiangnan University. -
Recent Advances in Nanomaterials Based Molecularly Imprinted Electrochemical Sensors
Nanotechnology and molecular imprinting both are omnipresent in the modern scientific world. Molecular recognition in the biological systems was mimicked to an extreme extent with its difficulties through molecular imprinting. Solving the problems related to this mimicking was the goal of science and technology. Some challenges like difficulties with the imprinting of protein, poor compatibility with aqueous environments, template leakage, and heterogeneous populations of binding sites in the polymers that contribute to a high level of nonspecific binding sites were addressed with recent advancement in the modern era. These issues were solved later with nano level instrumentations and inventions. Different types of nanomaterials were employed for this research on molecular recognition through MIPs to enhance selectivity, sensitivity and stability to specific systems such as sensors. This review paper attempts to give all the recent advances in molecular imprinting and the potential of nanomaterials in electrochemical sensors. 2021 Taylor & Francis Group, LLC. -
Reimagining North Korea in a new frame: review of the series Crash Landing on You (2019)
[No abstract available] -
Gratitude as a path to human prosperity during adverse circumstances: a narrative review
Although each person faces their own share of challenges, it is their individual perception and responses to these difficulties that determine how they are affected by them. In this paper we investigate the association between gratitude and human prosperity including the underlying mechanism that helps people thrive during trying circumstances. We survey the literature, examining how gratitude enables people to prosper amidst adversity and employ a narrative style to present these unique characteristics. This review suggests that gratitude enhances coping abilities, such as meaning-focused coping and positive reframing, which foster positive emotions and augment personal resources like resilience, perseverance, and social bonds. These elements, in turn, may possibly explain the association between gratitude and human prosperity during dire circumstances. 2023 Informa UK Limited, trading as Taylor & Francis Group. -
Essential Oil from Coriandrum sativum: A review on Its Phytochemistry and Biological Activity
Essential oils are hydrophobic liquids produced as secondary metabolites by specialized secretory tissues in the leaves, seeds, flowers, bark and wood of the plant, and they play an important ecological role in plants. Essential oils have been used in various traditional healing systems due to their pharmaceutical properties, and are reported to be a suitable replacement for chemical and synthetic drugs that come with adverse side effects. Thus, currently, various plant sources for essential oil production have been explored. Coriander essential oil, obtained from the leaf and seed oil of Coriandrum sativum, has been reported to have various biological activities. Apart from its application in food preservation, the oil has many pharmacological properties, including allelopathic properties. The present review discusses the phytochemical composition of the seed and leaf oil of coriander and the variation of the essential oil across various germplasms, accessions, at different growth stages and across various regions. Furthermore, the study explores various extraction and quantification methods for coriander essential oils. The study also provides detailed information on various pharmacological properties of essential oils, such as antimicrobial, anthelmintic, insecticidal, allelopathic, antioxidant, antidiabetic, anticonvulsive, antidepressant, and hepatoprotective properties, as well as playing a major role in maintaining good digestive health. Coriander essential oil is one of the most promising alternatives in the food and pharmaceutical industries. 2023 by the authors. -
Review on the Biogenesis of Platelets in Lungs and Its Alterations in SARS-CoV-2 Infection Patients
Thrombocytes (platelets) are the type of blood cells that are involved in hemostasis, thrombosis, etc. For the conversion of megakaryocytes into thrombocytes, the thrombopoietin (TPO) protein is essential which is encoded by the TPO gene. TPO gene is present in the long arm of chromosome number 3 (3q26). This TPO protein interacts with the c-Mpl receptor, which is present on the outer surface of megakaryocytes. As a result, megakaryocyte breaks into the production of functional thrombocytes. Some of the evidence shows that the megakaryocytes, the precursor of thrombocytes, are seen in the lungs interstitium. This review focuses on the involvement of the lungs in the production of thrombocytes and their mechanism. A lot of findings show that viral diseases, which affect the lungs, cause thrombocytopenia in human beings. One of the notable viral diseases is COVID-19 or severe acute respiratory syndrome caused by SARS-associated coronavirus 2 (SARS-CoV-2). SARS-CoV-2 caused a worldwide alarm in 2019 and a lot of people suffered because of this disease. It mainly targets the lung cells for its replication. To enter the cells, these virus targets the angiotensin-converting enzyme-2 (ACE-2) receptors that are abundantly seen on the surface of the lung cells. Recent reports of COVID-19-affected patients reveal the important fact that these peoples develop thrombocytopenia as a post-COVID condition. This review elaborates on the biogenesis of platelets in the lungs and the alterations of thrombocytes during the COVID-19 infection. 2023, SAGE Publications Ltd. All rights reserved. -
Green-synthesized nanoparticles and their therapeutic applications: A review
Antibiotic-resistant microorganisms are a rising issue when it comes to human health. Microbial pathogens that cause harmful infections are quickly becoming resistant to the antimicrobial action of traditional antibiotics. Nanotechnology, an innovative sector being an indispensable part of healthcare and research, has in-depth and extensive applications. Nano-compounds have been promising antimicrobial agents, anti-cancerous mediators, vehicles for drug delivery, formulations for functional foods, identification of pathogens, food and drug packaging industry, and many more. However, the chemical synthesis of nanoparticles (NPs) has certain drawbacks such as causing toxicity and other adverse effects. For more than a decade, the use of NPs that are conjugated or green-synthesized has gained popularity due to the two-fold action of metallic NPs mixed with biological sources. In contrast, NPs synthesized using plant or microbial extracts, conjugated with biologically active components, appear to be a safe alternative approach as they are environmentally friendly and cost-effective. Such environmentally safe techniques are referred to as "green nanotechnology"or "clean technology"and are feasible alternatives to chemical methods. Furthermore, NPs conjugated with natural biomolecules have improved bioavailability and have minimal side effects, as they are smaller in size and have higher permeability in addition to being reducing and stabilizing agents possessing excellent antioxidant activity. NPs serve as potential antimicrobial agents due to their affinity towards sulphur-rich amino acids, adhere to microbial cell walls by means of electrostatic attraction, and disrupt the cytoplasmic membrane along with the nucleic acid of microbes. They possess anticancer activity owing to oxidative stress, damage to cellular DNA, and lipid peroxidation. The green-synthesized NPs are thus a promising and safe alternative for healthcare therapeutic applications. 2023 the author(s), published by De Gruyter. -
Bioreactor systems for micropropagation of plants: present scenario and future prospects
Plant micropropagation has been adapted in the fields of agriculture, horticulture, forestry, and other related fields for large-scale production of elite plants. The use of liquid media and adoption of bioreactors have escalated the production of healthy plants. Several liquid-phase, gas-phase, temporary immersion, and other modified bioreactors have been used for plant propagation. The design, principle, operational mode, merits, and demerits of various bioreactors used for the regeneration of propagules, such as bulblets, cormlets, rhizomes, microtubers, shoots (subsequent rooting), and somatic embryos, are discussed here. In addition, various parameters that affect plant regeneration are discussed with suitable examples. Copyright 2023 Murthy, Joseph, Paek and Park. -
Disclosure of University Social Responsibility A Review of Select Higher Educational Institutions
This paper explores the disclosure of university social responsibility by higher educational institutions. Based on the disclosure of information on institutional websites, 39 universities were selected for the study. The data, which was assessed on the criteria used by regulatory authorities for grading institutions, revealed that while 12 institutions performed above average in most of the criteria, 17 were in the medium range, and 10 performed below average. The study proposes that disclosure of social responsibility activities with adequate evidence from institutional websites can attract more viewers and prospective students. 2023 Tata Institute of Social Sciences. All rights reserved. -
A Survey on P4 Challenges in Software Defined Networks: P4 Programming
Software Defined Networking (SDN) has been a prominent technology in the last decade that increases networking programmability. The SDN philosophy decouples the application, control, and data plane to increase the network programmability. The data plane is an essential but unsolved component that receives less attention than control and application planes. Traditionally, the data plane uses fixed functions that forward packets using a limited number of protocols. The P4 (Programming Protocol-independent Packet Processors) language makes it possible to program SDN data plane, which push the SDN to the next level. In the research community and industry, programming the data plane has garnered significant attention. Surprisingly, there has been no comprehensive reviews of programmable data-plane switches, which have many advantages in today's networks. The authors reviewed the evolution of networks from legacy to programmable data planes, explained the fundamentals of programmable switches, and summarized the network generation from traditional to programmable networks. In this paper, SDN is described from a P4-centric standpoint and discusses over 75 related research papers. Several taxonomies for the field are provided, outline potential research areas, and provide greater details regarding the patterns that have led to the development of this technology. 2013 IEEE. -
A Review on Advanced Nanomaterials for Antibacterial Applications
The management of infectious diseases is one of the major public health challenges of the 21st century. Mutation of the microbes, biofilm formation, and other structural-morpholo-gical behaviors have resulted in pathogens acquiring multi-drug resistance. The development of advanced materials that can provide long-lasting and effective protection against harmful microbes is becoming a need of the hour. Biocompatibility, efficient microbial inactivation, thermal and chemical stability of nanomaterials help to reduce the excessive use of antibiotics and, thus, to overcome antimicrobial resistance. Metal and metal oxide nanostructures, graphene, carbon dots, and other two-dimensional materials exhibit excellent antimicrobial properties. This review provides a comprehensive overview of antibacterial mechanisms and factors that help to inactivate the bacteria by nanomaterials. It also points out the enhanced antibacterial behaviors of the modified nanomaterials for future research concerns. 2023 Bentham Science Publishers. -
Examining the Domain of Green Finance Through Bibliometric Research Analysis of 22 Years (20002022): An Analytical Retrospective
Green finance has evolved as a concept aiming to integrate environmental protection and economic profits. Growing global concern towards climate change, greenhouse gas emissions, industrial pollution control, waste management, and environmental protection has caught the attention of countries and policymakers towards innovative financial products and services that are used to address a broader range of environmental concerns. Financial instruments such as green bonds, green stocks and loans effectively guide capital investment towards environment-friendly projects and promote the United Nations sustainable development goals. Thus, green finance is considered a compelling concept that plays a vital role in promoting sustainability. The authors used the Scopus database to perform a bibliometric review of green finance from 2001 to 2022 to determine the current trend and progress in the field. The article presents a thorough bibliometric and temporal analysis that provides inputs that other researchers on this topic have not evaluated. VoS Viewer and Biblioshiny. The software was used to visually analyse the data and identify patterns of co-occurrences and prominent research themes. The graphical and systematic mapping illustrates the evolution in publications over time and identifies areas of current research interests. The findings show that the research on green finance has gained momentum from 2014 onwards. The analysis provides a comprehensive overview of the green finance-related research, which will help the researchers and policymakers to examine better the trends and future direction of the development of green finance. 2023 MDI. -
Eco-friendly synthesized nanoparticles as antimicrobial agents: an updated review
Green synthesis of NPs has gained extensive acceptance as they are reliable, eco-friendly, sustainable, and stable. Chemically synthesized NPs cause lung inflammation, heart problems, liver dysfunction, immune suppression, organ accumulation, and altered metabolism, leading to organ-specific toxicity. NPs synthesized from plants and microbes are biologically safe and cost-effective. These microbes and plant sources can consume and accumulate inorganic metal ions from their adjacent niches, thus synthesizing extracellular and intracellular NPs. These inherent characteristics of biological cells to process and modify inorganic metal ions into NPs have helped explore an area of biochemical analysis. Biological entities or their extracts used in NPs include algae, bacteria, fungi, actinomycetes, viruses, yeasts, and plants, with varying capabilities through the bioreduction of metallic NPs. These biosynthesized NPs have a wide range of pharmaceutical applications, such as tissue engineering, detection of pathogens or proteins, antimicrobial agents, anticancer mediators, vehicles for drug delivery, formulations for functional foods, and identification of pathogens, which can contribute to translational research in medical applications. NPs have various applications in the food and drug packaging industry, agriculture, and environmental remediation. Copyright 2023 Borehalli Mayegowda, Roy, N. G., Pandit, Alghamdi, Almehmadi, Allahyani, Awwad and Sharma. -
Effectiveness of dialectical behavior therapy as a transdiagnostic treatment for improving cognitive functions: a systematic review
Dialectical behavior therapy (DBT) has been found to be an efficacious treatment for disorders characterized by high levels of emotional instability. In view of the multifaceted applications of DBT and the extent to which mental disorders can incapacitate cognitive functions, the current systematic review aimed to investigate the effect of DBT in strengthening cognitive functions across various mental health conditions. Original research studies employing both experimental and quasi-experimental designs were included in the review. The literature search was done using different electronic databases, from the first available literature until June 2022, that covered an approximate period of ten years. Joanna Briggs Institute checklist was used to assess the methodological rigor of the studies. Twelve studies conducted on adolescents with emotional dysregulation, and adults with borderline personality disorder, bipolar disorder, attention deficit hyperactivity disorder, and multiple sclerosis were selected. Results indicate that DBT has the potential to improve key cognitive functions such as attention, memory, fluency, response inhibition, planning, set shifting, tolerance for delayed rewards and time perception, as assessed by neuropsychological tests, self-report of cognitive functions, and neuroimaging techniques. Considering the review's findings that showcase the effectiveness of DBT in fostering improvements in cognitive functions, DBT may possibly be chosen as a preferred treatment to ensure that patients reach optimal levels of cognitive functioning. Limitations include lack of sufficient studies encompassing all the common mental health conditions, usage of neuroimaging techniques as only an indirect measure of cognitive functioning and nuances related to the quality of individual studies. Author(s), 2023. -
ANALYTICAL METHODS FOR TRAMADOL IN PHARMACEUTICAL AND FORENSIC CONTEXT A REVIEW
Tramadol is a centrally-acting weak opioid recept or analgesic and is a racemic mixture of (+)-tramadol and ()-tramadol enantiomers. Tramadol does not show many adverse severe effects without any dependency potential in therapeutic doses, as seen in other opioids only if not used for extended periods in doses higher than recommended. Symptoms of tramadol intoxication are similar to those of other opioid analgesics but may include serotonergic and noradrenergic components. Fatal intoxications are rare and appear synergetic with other drugs and alcohol. There is growing evidence of abuse of tramadol in many countries. Due to its extensive use in the medical field as an analgesic of choice, pharmaceutical analysis in both process and quality control is essential. Due to its abuse and overdose cases, forensic toxicological analysis of tramadol in body fluids and tissues is also vital in medico-legal practice. Tramadol and its metabolites are found in wastewater also. This analytical review (from 2016-2021) focuses on identifying and determining t ramadol in bulk dr ugs, formulations, forensic drug seizures, forensic toxicological specimens, and wastewater. The analytical methods covered include UV/Visible/IR spectrophotometric methods, thin-l ayer, gas and li quid chromat ographic met hods, electrochemical methods, GC-MS, LC-MS, LC-MS-MS methods, and electrochemical methods. The review will i nt eres t phar maceut i cal chemi st s, pharmacol ogis ts, biochemists, forensic chemists, forensic toxicologists, and environmental scientists. 2023, Medico Legal Society. All rights reserved. -
Functional Foods: Exploring the Health Benefits of Bioactive Compounds from Plant and Animal Sources
"Let food be the medicine"(Hippocrates) is a historic quote that became the basis of food science and nutraceuticals. Due to their possible therapeutic advantages, extracts from food have attracted much interest in the medical community. These extracts are abundant in bioactive compounds, which are natural molecules that may be found in various foods and have been demonstrated to affect health positively. Food components have lots of bioactive components, including primary and secondary metabolites and nutritional components, for example, carbohydrates, proteins, vitamins, minerals, fatty acids, antioxidants, phenolics, and flavonoids. This study's primary focus is on the make-up and purpose of these bioactive components found in food extracts. This review aims to give readers a thorough grasp of the bioactive substances found in food extracts and their possible physiological uses. These bioactive substances' functional traits, such as their antioxidant, anti-inflammatory, antibacterial, anticancer, and neuroprotective actions, are also studied. Further research is required to create new functional foods, nutraceuticals, and dietary supplements with specific health advantages that can benefit from understanding these molecules' structure and function. 2023 Versha Dixit et al. -
Tuning the output of the higher plants Circadian Clock
The circadian clock is an ascribed regulator found in the cells of creatures, that keeps biological and behavioral processes in stnc with dailt environmental changes throughout the 24-hour ctcles. When the circadian clock in humans malfunctions or is misaligned with environmental signals, the timing of the sleep-wake ctcle is altered and several circadian rhtthm sleep disorders result. Due to the Earth's rotation on its axis, predictable environmental changes are anticipated bt complex processes. The combined term for these ststems is the circadian clock. The circadian rhtthm regulates photostnthesis and photoperiodism, making it the "primart controller of plant life." The circadian clock is made up of post-translational alterations to core oscillators, epigenetic tweaks to DNA and histones, and auto regulatort feedback loops in transcription. In addition, the circadian clock is cell-autonomous and regulates the circadian rhtthms of distinct organs. Biochemical elements such as photostnthetic products, mineral nutrients, calcium ions, and hormones are used bt the core oscillators to communicate with one another. Arabidopsis is utilized to identift clock-related genes that govern plant growth, germination, pollination, flowering, abiotic and biotic stress responses, and more. The biological ctcles of all species, notablt humans, are undoubtedlt impacted bt other elements, including high altitude and changing ecoststems, in addition to the ones alreadt stated. Although it hasn't tet published ant experimental or scientific evidence to support them, the implication that living things have lives does appear inescapable. Hence, the present studt elaborates on the higher plants related to the circadian clock. The Author(s). -
A review on anti-cancer plants of India
India has a high level of endemism and a diverse range of floral species. Cancer is one of the most significant challenges facing global health today. The indigenous peoples and residents who live in India have, for a very long time, made use of specific medicinal plants to fight cancer. This practice is still prevalent today. Several different drugs may be utilized in the treatment of cancer. Because of the potential drawbacks associated with such treatments and the development of drug resistance, the quest for new therapies that are both safer and much more effective is still the most challenging field of study. Several cancer medicines used today come from natural sources. We're returning to our old ways because medicinal plants are a good, natural way to make medicines that prevent cancer without causing major side effects. Within the scope of this study, a few herbs traditionally used to treat cancer are looked at to see what they might be good for. The cytotoxicity of these plants, the processes that lead to them, and the different compounds they make were looked into. This study has tried to focus on how these plants fight cancer. The Author(s).